Table Of ContentMedicinal Research Reviews
Author Index to Vol. 19 (1999)
Argilés, Josep M.: The Role of Cytokines in Cancer Gaul, Beverly S.: See Post, Carol Beth 295
Cachexia, 223 Gentry, Elmer J.: See Mitscher, Lester A., 477
Georg, Gunda: See Flynn, Daniel, 341
Barlocco, Daniela: See Costantino, Luca, 3 Graneto, Mathew J.: See Talley, John J., 199
Beller, Matthias: Catalysis as a Key Technology for Grucza, R. A.: SH2 Domains: From Structure to
the Environmentally Benign Synthesis of Amines Energetics, A Dual Approach to the Study of
and Amino Acids, 357 Structure—Function Relationships, 273*
3ergbreiter, David E.: Alternative Polymer Supports
for Organic Chemistry, 439 Hardy, Dwight J.: See Fernandes, Prabhavathi B.,
Bertenshaw, Stephen R.: See Talley, John J., 199 559
Bolm, Carsten: Metal-Catalyzed Asy mmetric Hecker, Scott J.: See Lee, Ving J., 521
Oxidations, 348 Heuer, Kimberley I.: The Development Cycle of a
Bradshaw, J. M.: See Grucza, R. A., 273 Pharmaceutical Discovery Chemi-Informatics
Brown, David L.: See Talley, John J., 199 System, 209
Bryans, Justin S.: 3-Substituted GABA Analogs with Hinkle, Kevin, W.: See Wender, Paul A., 388
Central Nervous System Activity: A Review, 149
Kato, Shiro: Nitrogen-Containing Heteroalicycles
Carter, Jeffrey S.: See Talley, John J., 199 with Serotonin Receptor Binding Affinity:
Chu, Daniel T. W.: Recent Progress in Novel Development of Gastroprokinetic and Antiemetic
macrolides, Quinolones, and 2-Pyridones to Agents, 25
Overcome Bacterial Resistance, 497 Katz, Leonard: Novel Macrolides through Genetic
Cignarella, Giorgio: See Costantino, Luca, 3 Engineering, 543
Coe, Diane, M.: See Drewry, David H., 97 Koboldt, Carol M.: See Talley, John J., 199
Costantino, Luca: Diabetes Complications and Koehler, Michael F. T.: See Wender, Paul A., 388
Their Potential Prevention: Aldose Reductase Kourie, Joseph I.: Role of Natriuretic Peptides in
Inhibition and Other Approaches, 3 lon Transport Mechanisms, 75
Curran, Dennis P: Parallel Synthesis with Fluorous Kévesdi, Istvan: Application of Neural Networks in
Reagents and Reactants, 432 Structural—Activity Relationships, 249
DeJohn, Dana E.: See Loo, Joseph A., 307 Lee Kuo-Hsiung: Novel Antitumor Agents from
Dominguez-Rodriquez, Maria Felisa: See Ké6vesdi, Higher Plants, 569
Istvan, 249 Lee, Ving, J.: Antibiotic Resistance versus Small
Drewry, David, H.: Solid-Support Reagents in Molecules, the Chemical Evolution, 521
Organic Synthesis, 97 Lippa, Blaise: See Wender, Paul A., 388
Du, Ping: See Loo, Joseph A., 307 Loc, Joseph A.: Application of Mass Spectrometry
for Target Identification and Characterization,
Eisenmesser, Elan Zohar: See Post, Carol Beth, 295 307
Elsemore, David A.: See Fernandes, Prabhavathi B., Lopez-Soriano, Francisco J.: See Argilés, Josep M.,
559 223
Fernandes, Prabhavathi B.: Microbial Resistance: Masferrer, Jaime L.: See Talley, John J., 199
Novel Screens for a Contemporary Problem, Mattos, Carla: See Ringe, Dagmar, 321
559 Matyus, Péter: See Kévesdi, Istvan, 249
Flynn, Daniel L: Editorial Announcement, 1 McDaniel, Robert: See Katz, Leonard, 543
————: Editorial Preface, 271 Mendonca, Aubrey J.: Optimization of Solid
———- Editorial Preface, 341 Supports for Combinatorial Chemical Synthesis,
———: Phase-Trafficking Reagents and Phase- 451
Switching Strategies for Parallel Synthesis, 408 Menzel, Rolf: See Fernandes, Prabhavathi B., 559
Fujiwara, Iwao: See Kato, Shiro, 25 Mitscher, Lester A.: Introduction to Special Issue on
Fiitterer, K.: See Grucza, R. A., 273 Multiple Drug Resistance, 475
Medicinal Research Reviews, Vol 19, No. 6, 603-604 (1999)
© 1999 John Wiley & Sons, Inc CCC 0198-6325/99/060603-02
603
AUTHOR INDEX
Multiple Drug Resistance, 477 Schneider, Michael L.: See Post, Carol Beth, 295
: The Retirement of Ruby deStevens, 95 Seibert, Karen: See Talley, John J., 199
Murphy, Kenneth P.: Predicting Binding Energetics Shankel, Delbert M.: See Mitscher, Lester A., 477
from Structure: Looking Beyond AG’, 333 Snieckus, Victor: Optimization in Organic
Synthesis, 342
Naray-Szab6, Gabor: See Kovesdi, Istvan, 249 —. See Flynn, Daniel, 341
Norman, Bryan H.: See Talley, John J., 199 Stevenson, Tracy I.: See Loo, Joseph A., 307
Stork, Gilbert: Some Contributions to Regio and
Orfi, Laszl6: See Kévesdi, Istvan, 249 Stero Control: From Cincholoipon and
Ogorzalek Loo, Rachel R.: See Loo, Joseph A., 307 Cantharidin to the Present, 370
Papp, Julius Gy.: See Kévesdi, Istvan, 249 falley, John J.: 4,5-Diaryloxazole Inhibitors of
Pilipauskas, Daniel R.: Can the Time From Cyclooxygenase-2 (COX-2), 199
Synthesis Design to Validated Chemistry be [se-Dinh, Yuk-Ching: See Fernandes, Prabhavathi
Shortened?, 463 B., 559
Pillai, Segaran P.: See Mitscher, Lester A., 477 Varro, Andras: See Kévesdi, Istvan, 249
Poon, Steve: See Drewry, David H., 97 Vianello, Paola: See Costantino, Luca, 3
Post, Carol Beth: NMR Structure of Phspho-
Tyrosine Signaling Complexes, 295 Waksman, G.: See Grucza, R. A., 273
Warren, Alicia: See Fernandes, Prabhavathi B., 559
Rafferty, Michael F.: See Flynn, Danie) } Wender, Pau) A.: The Rational Design of Potential
See Flynn, Daniel, 271 Chemotherapeutic Agents: Synthesis of
Rastelli, Giulio: See Costantino, Luca, 3 3ryostatin Analogues, 388
Ringe, Dagmar: Analysis of the Binding Surfaces of Wustrow, David J.: See Bruans, Justin S., 149
Proteins, 321
Rive, Megan J.: See Kourie, Joseph L., 75 Xiao, Xiao-Yi: See Mendonca, Aubrey J., 451
Rogier, Jr, D. Joseph: See Talley, John J., 199
Yoshida, Naoyuki: See Kato, Shiro, 25
Sanderson, Philip E. |.. Small, Noncovalent Serine
Protease Inhibitors, 179 Zweifel, Ben S.: See Talley, John J., 199
Medicinal Research Reviews
Title Index to Vol. 19 (1999)
Alternative Polymer Supports for Organic Chemistry
David E. Bergbreiter
Analysis of the Binding Surfaces of Proteins
Dagmar Ringe and Carla Mattos
Antibiotic Resistance versus Small Molecules, the Chemical Evolution
Ving J. Lee and Scott J. Hecker
Application of Mass Spectrometry for Target Identification and Characterization
Joseph A. Loo, Dana E. Defohn, Tract I. Stevenson, and Rachel Ogorzalek Loo
Application of Neural Networks in Structure—Activity Relationships
Istvan Kovesdi, Maria Felisa Dominguez-Rodriguez, Laszlé Orfi, Gabor Naray-Szab6,
Andras Varro, Julius Gy. Papp, and Péter Matyus
Can the Time From Synthesis Design to Validated Chemistry be Shortened?
Daniel R. Pilipauskas
Catalysis as a Key Technology for the Environmentally Benign Synthesis
of Amines and Amino Acids
Matthias Beller
Diabeties Complications and Their Potential Prevention: Aldose Reductase
Inhibition and Other Approaches
Luca Costantino, Giulio Rastelli, Paola Vianello, Giorgio Cignarella,
and Daniela Barlocco
Editorial Announcement
Daniel L. Flynn and Michael F. Rafferty
Editorial Preface
Dantel Flynn and Michael F Rafferty
Editoria) Pretace
Dantet Fiyn, Gunda Georg, and Victor Snieckus ©... cc cc cece cece ecncaees 341
4,5-Diaryloxazole [Inhibitors of Cyclooxygenase-2 (COX-2)
John J. Talley, Stephen R. Bertenshaw, David L. Brown, Jeffrey S. Carter,
Mathew J. Graneto, Carol M. Koboldt, jaime L. Masferrer, Bryan H. Norman,
D. Joseph Rogier, )r., Ben S. Zweife), and Karen Seibert
Introduction to Special Issue on Multiple Ding Resistance
Lester A. Mitscher
Metal-Catalyzed Asymmetric Oxidations
Carsten Bolm
Medicinal Research Reviews, Vol. 19, No. 6, 605-607 (1999)
© 1999 John Wiley & Sons, Inc CCC 0198-6325/99/060605-03
606 °«
Microbial Resistance: Novel Screens for a Contemporary Problem
Prabhavathi B. Fernandes, Rolf Menzel, Dwight J]. Hardy, Yuk-Ching Tse-Dinh,
Alicia Warren, and David A. Elsemore
Multiple Drug Resistance
Lester A. Mitscher, Segaran P. Pillai, Elmer J]. Gentry, and Delbert M. Shankel
Nitrogen-Containing Heteroalicycles with Serotonin Receptor Binding Affinity:
Development of Gastoprokinetic and Antiemetic Agents
Shiro Kato, Iwao Fujiwara, and Naoyuki Yoshida
NMR Structure of Phospho-Tyrosine Signaling Complexes
Carol Beth Post, Beverly S. Gaul, Elan Zohar Eisenmesser,
and Michael L. Schneider
Novel Antitumor Agents from Higher Plants
Kuo-Hstung Lee
Novel Macrolides through Genetic Engineering
Leonard Katz and Robert McDaniel .
Optimization in Organic Synthesis
Victor Snieckus
Optimization of Solid Supports for Combinatorial Chemical Synthesis
Aubrey J]. Mendonca and Xiao-Yi Xiao
Parallel Synthesis with Flourous Reagents and Reactants
Dennis P. Curran
Phase-Trafficking Reagents and Phase-Switching Strategies for Parallel Synthesis
Daniel L. Flynn
Predicting Binding Energetics from Structure: Looking Beyond AG°
Kenneth P. Murphy
Recent Progress in Novel Macrolides, Quinolones, and 2-Pyridones to Overcome
Bacterial Resistance
Daniel T. W. Chu
Role of Natriuretic Peptides in Ion Transport Mechanisms
Joseph I. Kouri and Megan J. Rive
SH2 Domains: From Structure to Energetics, a Dual Approach to the Study
of Structure-Function Relationshops
R. A. Grucza, ]. M. Bradshaw, K. Fiitterer, and G. Waksman
Small, Noncovalent Serine Protease Inhibitors
Philip E. J. Sanderson . .
Solid-Support Reagents in Organic Synthesis
David H. Drewry, Diane M. Coe, and Steve Poon
Some Contributions to Regio and Stereo Control: From Cincholoipon
and Cantharidin to the Present
Gilbert Stork
TITLE INDEX *
The Development Cycle of a Pharmaceutical Discovery Chemi-Informatics System
Kimberley I. Heuer
The Rational Design of Potential Chemotherapeutic Agents: Synthesis
of Bryostatin Analogues
Paul A. Wender, Kevin W. Hinkle, Michael F. T. Koehler, And Blaise Lippa....
The Retirement of Ruby deStevens
Lester A. Mitscher
The Role of Cytokines in Cancer Cachexia
Josep M. Argilés and Francisco J]. Lopez-Soriano
3-Substituted GABA Analogs with Central Nervous System Activity: A Review
Justin S. Bryans and David J. Wustrow
