Mayo Clinic Antimicrobial Therapy

390 Pages·2011·2.43 MB·English

by  Mayo Clinic

Mayo Clinic
Antimicrobial Therapy
Second Edition
Mayo Clinic Scientifi c Press
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Mayo Clinic
Antimicrobial Therapy
Quick Guide
Second Edition
Editors
John W. Wilson, MD
Consultant
Division of Infectious Diseases, and
Assistant Professor of Medicine
College of Medicine, Mayo Clinic
Rochester, Minnesota
Lynn L. Estes, PharmD
Clinical Pharmacy Specialist
Assistant Professor of Pharmacy
College of Medicine, Mayo Clinic
Rochester, Minnesota
MAYO CLINIC SCIENTIFIC PRESS
OXFORD UNIVERSITY PRESS
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_______________________________________________
Library of Congress Cataloging-in-Publication Data
Wilson, John W., 1967-
Mayo Clinic antimicrobial therapy : quick guide / John W. Wilson, Lynn L. Estes. — 2nd ed.
p. ; cm.
Antimicrobial therapy
Rev. ed. of: Mayo Clinic antimicrobial therapy. c2008.
Includes bibliographical references and index.
ISBN 978-0-19-979778-3 (pbk.)
1. Anti-infective agents—Handbooks, manuals, etc. 2. Communicable diseases—Chemotherapy—
Handbooks, manuals, etc. I. Estes, Lynn L. II. Mayo Clinic. III. Mayo Clinic antimicrobial therapy. IV. Title.
V. Title: Antimicrobial therapy.
[DNLM: 1. Anti-Infective Agents—therapeutic use—Handbooks. 2. Communicable Diseases—drug
therapy—Handbooks. QV 39]
RM262.M377 2012
615’.1—dc23 2011018569
_______________________________________________
Mayo Foundation does not endorse any particular products or services, and the reference to any products
or services in this book is for informational purposes only and should not be taken as an endorsement by
the authors or Mayo Foundation. Care has been taken to confi rm the accuracy of the information
presented and to describe generally accepted practices. However, the authors, editors, and publisher are
not responsible for errors or omissions or for any consequences from application of the information in this
book and make no warranty, express or implied, with respect to the contents of the publication. This book
should not be relied on apart from the advice of a qualifi ed health care provider.
The authors, editors, and publisher have exerted efforts to ensure that drug selection and dosage set forth
in this text are in accordance with current recommendations and practice at the time of publication.
However, in view of ongoing research, changes in government regulations, and the constant fl ow of
information relating to drug therapy and drug reactions, readers are urged to check the package insert for
each drug for any change in indications and dosage and for added wordings and precautions. This is
particularly important when the recommended agent is a new or infrequently employed drug.
Some drugs and medical devices presented in this publication have US Food and Drug Administration
(FDA) clearance for limited use in restricted research settings. It is the responsibility of the health care
providers to ascertain the FDA status of each drug or device planned for use in their clinical practice.
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Printed in United States of America
on acid-free paper
We dedicate this book to the patients under our care and to our families,
who continue to support us in our work.

vii
About the Cover
The cover image illustrates the “journey to wellness” that patients and
their health care providers make through the appropriate use of antimi-
crobial therapy for infectious diseases. Health care providers and scien-
tists worldwide have an opportunity and growing responsibility, through
microbial epidemiology and antimicrobial stewardship, to collectively
work toward optimal diagnosis and management of infectious diseases.

ix
Preface
The medical management of infectious diseases and antimicrobial therapy
can be a daunting task for health care professionals. Although expansive
textbooks and online resources are available, we believe that a more
simplifi ed, quick reference guide is needed for the day-to-day offi ce and
hospital clinical practice. This book is designed to provide information
about infectious diseases and antimicrobial therapy in a format that is
readily accessible and easily applicable to the clinical environment.
Highlights of this book include simplifi ed and thorough drug dosing
recommendations for renal function and renal replacement therapies,
drugs of choice for specifi c organisms (including bacteria, fungi, and
viruses), and simplifi ed antimicrobial and management recommendations
for specifi c infectious syndromes.
We hope this book will assist health care providers in the management
of infectious diseases and in the selection of appropriate antimicrobial
therapy in a time-effi cient manner. This book is not meant to serve as a
comprehensive review of all infectious diseases topics. Instead, readers
are encouraged to seek supplemental information from additional
published resources and from the prescribing information provided by
pharmaceutical manufacturers.