Marine biomaterials : characterization, isolation, and applications

820 Pages·2013·153.78 MB·English

by  Se-Kwon Kim

Biomedical Engineering
Kim
Marine Biomaterials
CM
h
Characterization, Isolation
a
ra
a
and Applications
c
r
t
e
i
rn
i
z
Oceans are an abundant source of diverse biomaterials with potential a
for an array of uses. Marine Biomaterials: Characterization, Isolation te
i
o
and Applications brings together the wide range of research in this
n
important area, including the latest developments and applications,
,
from preliminary research to clinical trials. The book is divided into four B
I
parts, with chapters written by experts from around the world. Bioma- s
o
terials described come from a variety of marine sources, such as fish, i
algae, microorganisms, crustaceans, and mollusks. lao
t
i
o
Part I covers the isolation and characterization of marine bioma- m
n
terials—bioceramics, biopolymers, fatty acids, toxins and pigments,

nanoparticles, and adhesive materials. It also describes problems that a
may be encountered in the process as well as possible solutions. Part II na
looks at biological activities of marine biomaterials, including polysac- d
charides, biotoxins, and peptides. Chapters examine health benefits of At
the biomaterials, such as antiviral activity, antidiabetic properties, anti- pe
coagulant and anti-allergic effects, and more.
p
lr
i
Part III discusses biomedical applications of marine biomaterials, in- c
i
cluding nanocomposites, and describes applications of various mate- aa
rials in tissue engineering and drug delivery. Part IV explores commer- t
i
o
cialization of marine-derived biomaterials—marine polysaccharides
l
n
and marine enzymes—and examines industry perspectives and ap- s
s
plications. This book covers the key aspects of available marine bio-
materials for biological and biomedical applications, and presents
techniques that can be used for future isolation of novel materials from
marine sources.
K14576
ISBN: 978-1-4665-0564-3
90000
9 781466 505643
K14576_COVER_final_revised.indd 1 3/13/13 11:01 AM
Marine
Biomaterials

Marine
Biomaterials
Characterization, Isolation
and Applications
Edited by
Se-Kwon Kim
CRC Press
Taylor & Francis Group
6000 Broken Sound Parkway NW, Suite 300
Boca Raton, FL 33487-2742
© 2013 by Taylor & Francis Group, LLC
CRC Press is an imprint of Taylor & Francis Group, an Informa business
No claim to original U.S. Government works
Version Date: 20121220
International Standard Book Number-13: 978-1-4665-0565-0 (eBook - PDF)
This book contains information obtained from authentic and highly regarded sources. Reasonable efforts have been made to
publish reliable data and information, but the author and publisher cannot assume responsibility for the validity of all materials
or the consequences of their use. The authors and publishers have attempted to trace the copyright holders of all material repro-
duced in this publication and apologize to copyright holders if permission to publish in this form has not been obtained. If any
copyright material has not been acknowledged please write and let us know so we may rectify in any future reprint.
Except as permitted under U.S. Copyright Law, no part of this book may be reprinted, reproduced, transmitted, or utilized in any
form by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying, microfilming,
and recording, or in any information storage or retrieval system, without written permission from the publishers.
For permission to photocopy or use material electronically from this work, please access www.copyright.com (http://www.copy-
right.com/) or contact the Copyright Clearance Center, Inc. (CCC), 222 Rosewood Drive, Danvers, MA 01923, 978-750-8400.
CCC is a not-for-profit organization that provides licenses and registration for a variety of users. For organizations that have been
granted a photocopy license by the CCC, a separate system of payment has been arranged.
Trademark Notice: Product or corporate names may be trademarks or registered trademarks, and are used only for identifica-
tion and explanation without intent to infringe.
Visit the Taylor & Francis Web site at
http://www.taylorandfrancis.com
and the CRC Press Web site at
http://www.crcpress.com
Contents
Preface ..............................................................................................................................................ix
Acknowledgments .........................................................................................................................xi
Editor.............................................................................................................................................xiii
Contributors ...................................................................................................................................xv
Part I Isolation and Characterization of Marine Biomaterials
1. Introduction to Marine Biomaterials .................................................................................3
Se-Kwon Kim and Jayachandran Venkatesan
2. Hydroxyapatite from Marine Fish Bone: Isolation
and Characterization Techniques .....................................................................................17
Jayachandran Venkatesan and Se-Kwon Kim
3. Hydroxyapatite and Calcium Phosphates from Marine Sources:
Extraction and Characterization ........................................................................................29
Clara Piccirillo, Manuela M. Pintado, and Paula M.L. Castro
4. Isolation and Characterization of Chitin and Chitosan
as Potential Biomaterials ....................................................................................................45
Nitar Nwe, Tetsuya Furuike, and Hiroshi Tamura
5. Structure Elucidation and Biological Effects of Carrageenans from Red Algae ......61
Wei Zhang, Ming Liu, and Poul Erik Hansen
6. Study of Marine-Derived Fatty Acids and Their Therapeutic Importance ..............79
Parimal C. Sen
7. Marine Toxins for Natural Products Drug Discovery ..................................................89
Muthuvel Arumugam, Thangavel Balasubramanian, and Se-Kwon Kim
8. Conotoxins: A Source of Biomaterial for Pharmacology and Neuroscience ..........107
Ngo Dang Nghia
9. Pigmented Marine Heterotrophic Bacteria: Occurrence, Diversity,
and Characterization of Pigmentation ...........................................................................117
Marit H. Stafsnes and Per Bruheim
10. Antitumor Pigments from Marine Bacteria ..................................................................149
Azamjon B. Soliev and Keiichi Enomoto
11. Structural Characteristics of Bioactive Marine Natural Products ............................173
Snezana Agatonovic-Kustrin, David Morton, and Christine Kettle
v
vi Contents
12. Environmental and Human Impact on Marine
Microorganism–Synthesized Nanoparticles ................................................................253
L. Karthik, Gaurav Kumar, and K.V. Bhaskara Rao
13. Biosynthesis and Characterization of Different Nanoparticles
and Its Larvicidal Activity against Human Disease Vectors.....................................273
Arivarasan Vishnu Kirthi, Chidambaram Jayaseelan, and Abdul Abdul Rahuman
14. Mussel-Derived Adhesive Biomaterials ........................................................................289
Dong Soo Hwang, Yoo Seong Choi, and Hyung Joon Cha
Part II Biological Activities of Marine Biomaterials
15. Biological Applications of Marine Biomaterials ..........................................................313
A. Malshani Samaraweera and Janak K. Vidanarachchi
16. Health Benefits of Sulfated Polysaccharides from Marine Algae ............................333
Se-Kwon Kim, Dai-Hung Ngo, Thanh-Sang Vo, and Dai-Nghiep Ngo
17. Biological Activities and Potential Applications of Marine Biotoxins ...................345
Alberto Otero, María José Chapela, Jorge Lago, Juan M. Vieites, and Ana G. Cabado
18. Compounds from Marine Organisms with Antiviral Activity ................................397
Se-Kwon Kim, Fatih Karadeniz, and Mustafa Zafer Karagozlu
19. Biological Activities of Marine-Derived Bioactive Peptides .....................................405
Chen Zhang, Yuanfeng Ruan, and Se-Kwon Kim
20. Health Beneficial Effects of Docosahexaenoic Acid: A Marine Treasure ...............413
Na-Young Song and Young-Joon Surh
21. Treatment of Obesity and Diabetes with Marine-Derived Biomaterials ...............437
Se-Kwon Kim, Fatih Karadeniz, and Mustafa Zafer Karagozlu
22. Potential Anticoagulant Effect of Seaweed-Derived Biomaterials ..........................447
Se-Kwon Kim and Quang Van Ta
23. Microbial Biomaterials and Their Applications ..........................................................457
Se-Kwon Kim, Ira Bhatnagar, and Ramjee Pallela
24. Marine Biomaterials for Antiallergic Therapeutics ....................................................467
Se-Kwon Kim, Thanh-Sang Vo, and Dai-Hung Ngo
Contents vii
Part III Biomedical Applications of Marine Biomaterials
25. Biomedical Potential of Unchlorinated Briarane Diterpenes from Gorgonians
and Sea Pens ........................................................................................................................481
Bruce F. Bowden and Ioana M. Vasilescu
26. Application of Marine Collagen–Based Scaffolds in Bone Tissue Engineering ....519
Ramjee Pallela, Jayachandran Venkatesan, Ira Bhatnagar, Yoon-Bo Shim,
and Se-Kwon Kim
27. Biocomposites Containing Chitosan for Bone Tissue Engineering ........................529
Sekaran Saravanan, Mohita Trivedi, Ambigapathi Moorthi,
and Nagarajan Selvamurugan
28. Marine Plants and Algae as Promising 3D Scaffolds for Tissue Engineering ......541
M. López-Álvarez, J. Serra, J.M. Sánchez, A. de Carlos, and P. González
29. Application of Marine Biomaterials in Orthopedic and Soft
Tissue Surgical Challenges ..............................................................................................561
Samit Kumar Nandi, Uttam Datta, and Subhasish Biswas
30. Marine Materials in Drug Delivery and Tissue Engineering:
From Natural Role Models to Bone Regeneration and Repair and Slow
Delivery of Therapeutic Drugs, Proteins, and Genes .................................................575
Besim Ben-Nissan and David W. Green
31. Polysaccharides from Seaweeds: Modification and Potential
Application in Drug Delivery ..........................................................................................603
Héctor J. Prado, María C. Matulewicz, Pablo R. Bonelli, and Ana L. Cukierman
32. Marine Biomaterials: Role in Drug Delivery and Tissue
Engineering toward Biomedical Applications .............................................................633
Devarai Santhosh Kumar and Kota Sobha
33. Application of Marine Biomaterials for Gene Delivery .............................................657
You-Kyoung Kim, Hu-Lin Jiang, Bijay Singh, Yun-Jaie Choi, Myung-Haing Cho,
Toshihiro Akaike, and Chong-Su Cho
34. Advantages of Chitin-Based Nanobiomaterials in Nanomedicine ..........................673
S. Sowmya, Shantikumar V. Nair, and R. Jayakumar
35. Chitin Nanofibrils for Biomimetic Products: Nanoparticles
and Nanocomposite Chitosan Films in Health Care ...................................................681
P. Morganti, G. Tishchenko, M. Palombo, I. Kelnar, L. Brozova, M. Spirkova,
E. Pavlova, L. Kobera, and F. Carezzi
viii Contents
36. Role of Nanocomposites and Nanostructured Biomaterials in Biomedical
and Nanobiotechnology ....................................................................................................717
Abdul Bakrudeen Ali Ahmed, R. Arun Kumar, and Rosna Mat Taha
Part IV Industrial Applications of Marine-Derived Biomaterials
37. Industry Perspectives of Marine-Derived Proteins as Biomaterials .......................737
Se-Kwon Kim, Dai-Hung Ngo, Thanh-Sang Vo, and BoMi Ryu
38. Marine Polysaccharide (Chitosan) and Its Derivatives as Water Purifier ..............747
Y. Dominic Ravichandran and R. Rajesh
39. Industrial Applications of Marine Polysaccharides ....................................................765
S.N. Joshi, A.N. Bedekar, and P.N. Sudha
40. Application of Enzymes from Marine Microorganisms ............................................787
Xiujuan Shi, E. Song, and Chen Zhang
Preface
Oceans not only consist of water but are also an abundant source of diverse biomaterials
to mankind. Although marine biomaterial is an emerging area of research with significant
applications, its usage is limited due to lack of research. To date, countable specific books
are available for marine biomaterials as per my scientific knowledge. To bridge this gap
and to provide a more comprehensive coverage of marine biomaterials, I decided to com-
pile this literary work. This book presents the development of marine biomaterials and
discusses various topics such as isolation and their characterization as well as applications
from the preliminary research to clinical trials.
The focus of this book, Marine Biomaterials: Characterization, Isolation and Applications, is
to provide an up-to-date coverage of marine biomaterials. The book has been divided into
four major parts:
• Part I: Isolation and Characterization of Marine Biomaterials
Marine biomaterials have a wide range of bioactivity, which can be utilized
only once the isolation and characterization are accomplished in an appropriate
manner. Part I covers the isolation and characterization of marine biomaterials
(bioceramics, biopolymers, fatty acids, toxins and pigments, nanoparticles, and
adhesive materials) and problems associated with them together with probable
solutions for the same.
• Part II: Biological Activities of Marine Biomaterials
Proper characterization ensures further use of the isolated/purified marine bio-
material in different applications. Part II deals mainly with biological applications
of marine-derived biomaterials, for example, health benefits, potential biological
activities of peptides, and biotoxins. In addition, antiviral activity, antidiabetic
properties, and anticoagulant and anti-allergic effects of marine biomaterials have
also been explored.
• Part III: Biomedical Application of Marine Biomaterials
In recent days, significant development has been achieved with marine-derived
bionanomaterials and nanocomposites in the area of biomedical applications (tissue
engineering and drug delivery), and this is explored in Part III. Subsequently,
several subsections deal with marine-derived chitosan and collagen usage in
tissue engineering and scaffolding systems. The applicability of marine bioma-
terials in the drug delivery arena has also been discussed in light of the current
available literature.
• Part IV: Industrial Application of Marine-Derived Biomaterials
Last but not the least, the characterized material must reach the market, but
for that it needs to be scaled up to the pilot plant level, which can be done only
through industrialization. Part IV provides information about this important step
of commercialization of marine biomaterials. This part includes the industrial
application of marine polysaccharides and marine enzymes.
Various experts from around the globe (Europe, India, Asia-Pacific, Australia, Japan, Korea,
and Vietnam) have contributed their knowledge and experience in the form of chapters
ix