Table Of ContentManual of STEMI Interventions
Manual of STEMI Interventions
Edited by Sameer Mehta MD FACC MBA
University of Miami Miller School of Medicine,
and Lumen Foundation, Miami, FL, USA
This edition first published 2017 © 2017 by John Wiley & Sons Ltd
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Library of Congress Cataloging‐in‐Publication Data
Names: Mehta, Sameer, editor.
Title: Manual of STEMI interventions / edited by Sameer Mehta.
Description: Hoboken, NJ : Wiley, 2017. | Includes index. |
Identifiers: LCCN 2017014480 (print) | LCCN 2017015848 (ebook) | ISBN 9781119095439 (pdf) |
ISBN 9781119095422 (epub) | ISBN 9781119095415 (cloth)
Subjects: | MESH: Myocardial Infarction–therapy | Anticoagulants–therapeutic use | Stents
Classification: LCC RC685.I6 (ebook) | LCC RC685.I6 (print) | NLM WG 310 | DDC 616.1/23706–dc23
LC record available at https://lccn.loc.gov/2017014480
Cover design: Wiley
Cover images: (From left to right) © Feverpitched/Gettyimages; © Ryan McVay/Gettyimages;
© Nils Versemann/Shutterstock; © kupicoo/Gettyimages
Set in 10/12pt Warnock by SPi Global, Pondicherry, India
10 9 8 7 6 5 4 3 2 1
v
Contents
List of Contributors ix
Preface xiii
Part I Guidelines, Thrombolytic Therapy, Pharmacology 1
1 Compendium of STEMI Clinical Trials 3
Juanita Gonzalez Arango MD, Miguel Vega Arango MD, Estefania Calle Botero MD,
Isaac Yepes Moreno MD, Maria Botero Urrea MD, Alicia Henao Velasquez MD, Daniel Rodriguez MD,
Daniela Parra Dunoyer MD, Maria Teresa Bedoya Reina MD, Sameer Mehta MD
2 European Society of Cardiology and American College of Cardiology STEMI Guidelines 35
Estefania Oliveros MD, Sameer Mehta MD FACC, Alexandra Ferré MD, Tracy Zhang BS,
Michael Schweitzer MD, Miguel Vega Arango MD, Juanita Gonzalez Arango MD,
Maria Botero Urrea MD, Maria Teresa Bedoya Reina MD, Isaac Yepes MD
3 The Role of Thrombolytic Therapy in the Era of STEMI Interventions 55
Nestor Mercado MD, Theodore L. Schreiber MD, Cindy L. Grines MD
4 Anticoagulants in STEMI Interventions 65
Vincenzo Vizzi MD, Thomas W. Johnson BSc MBBS MD FRCP, Andreas Baumbach MD
5 New Oral and Intravenous Adenosine Diphosphate Blockers in STEMI Intervention 75
James J. Ferguson III MD
Part II The STEMI Procedure 105
6 The Role of Acute Circulatory Support in STEMI 107
Yousef Bader MD, Navin K. Kapur MD
7 Thrombus Management for STEMI Interventions 119
Sameer Mehta MD, Olga Reynbakh MD, Daniel Rodriguez MD, Tracy Zhang BS, Michael Schweitzer
MD, Maria Teresa Bedoya Reina MD, Miguel Vega Arango MD, Juanita Gonzalez Arango MD,
Maria Botero Urrea MD
vi Contents
8 Transradial Techniques to Improve STEMI Outcomes 145
Tejas Patel MD DM FACC FESC FSCAI, Sanjay Shah MD DM, Samir Pancholy MD FACC FSCAI
9 Management of Cardiogenic Shock 159
Holger Thiele MD, Suzanne de Waha MD
10 Present Role of Thrombectomy in STEMI Interventions 171
Francesco Giannini MD, Azeem Latib MD, Antonio Colombo MD
11 Choice of Stent in STEMI Interventions 187
Roopa Salwan MD
12 Illustrated STEMI Procedures I – Basic STEMI Skills 207
Sameer Mehta MD, Tracy Zhang BS, Michael Schweitzer MD, Alexandra Ferré MD,
Daniella Nacad MD, Landy Luna Diaz MD, Alicia Henao Velasquez MD
13 Illustrated STEMI Procedures II – Basic STEMI Skills 223
Sameer Mehta MD, Tracy Zhang BS, Michael Schweitzer MD, Alexandra Ferré MD,
Daniella Nacad MD, Landy Luna Diaz MD, Alicia Henao Velasquez MD
14 Illustrated STEMI Procedures III – Basic STEMI Skills 239
Sameer Mehta MD, Tracy Zhang BS, Michael Schweitzer MD, Alexandra Ferré MD,
Daniella Nacad MD, Landy Luna Diaz MD, Alicia Henao Velasquez MD
15 Remote Ischemic Conditioning for Acute Myocardial Infarction 255
Hans Erik Bøtker MD PhD FACC FESC, Gerd Heusch MD FACC FESC FRCP
Part III The STEMI Process 273
16 Reducing Door‐to‐Balloon Times 275
Michel Le May MD, Joshua PY Loh MD
17 Pre‐hospital Triage and Management 285
Ivan Rokas MD
18 Creating Networks for Optimal STEMI Management 299
David C. Lange MD, David M. Larson MD, David Hildebrandt RN, Timothy D. Henry MD
19 Pharmacoinvasive Management of STEMI 315
Neeraj Bhalla MD
Part IV Global STEMI Initiatives 325
20 Stent for Life: The European Perspective on STEMI Interventions 327
Sasko Kedev MD PhD FESC FACC
21 Urban Combined Pharmacoinvasive Management of STEMI Patients as Antidote
to Traffic in Large Metropolitan Cities 333
David G. Iosseliani MD FACC FESC
Contents vii
22 Lessons from the Puerto Rico Infarction National Collaborative Experience Initiative 343
Orlando Rodríguez‐Vilá MD MMS FACC FSCAI, Jose Escabi‐Mendoza MD FACC,
Fernando Lapetina‐Irizarry MD FACC, Miguel A. Campos‐Esteve MD FACC
23 The STEMI Care Program in China 357
Yan Zhang MD, Yong Huo MD
24 STEMI INDIA 363
Thomas Alexander MD, Ajit S Mullasari MD
25 The Role of Telemedicine in STEMI Interventions 371
Roberto Vieira Botelho MD PhD, Sameer Mehta MD FACC MBA, Julius Cezar Q. Ladeira DDS MSc,
Francisco Fernandéz MBA, Márcio Sanches MD, Denis Fabiano de Souza RN,
Wladimir Fernandes de Rezende MBA, Carlos Otávio Lara Pinheiro BSc
26 Innovative Telemedicine STEMI Protocols 379
Sameer Mehta MD FACC MBA, Roberto Vieira Botelho MD PhD, Freddy Bojanini MD,
Juan Corral MD, Marco Perin MD, María Teresa Bedoya Reina MD, Juliana Giraldo MD,
Laura Álvarez MD, Cindy Manotas MD, Sebastián Moreno MD, Sergio Reyes MD, María Botero
Urrea MD
Part V Future Perspectives 395
27 STEMI Interventions, Beyond the Culprit Lesion 397
Neil Ruparelia PhD MRCP, Antonio Colombo MD, Azeem Latib MD
28 Promising Technologies for STEMI Interventions 409
Joshua PY Loh MD, HC Tan
Index 421
ix
List of Contributors
Thomas Alexander MD Hans Erik Bøtker MD PhD FACC FESC
Kovai Medical Center and Hospital, Department of Cardiology, Aarhus
Coimbatore, India University Hospital Skejby, Aarhus,
Denmark
Laura Álvarez MD
Miguel A. Campos‐Esteve MD FACC
Lumen Foundation, Miami, FL, USA
Cardiac Catheterization Laboratories,
Juanita Gonzalez Arango MD Pavia Hospital Santurce, San Juan, Puerto Rico,
USA
Lumen Foundation, Miami, FL, USA
Antonio Colombo MD
Miguel Vega Arango MD
Interventional Cardiology Unit,
Lumen Foundation, Miami, FL, USA
San Raffaele Scientific Institute, Milan,
Italy; Interventional Cardiology Unit,
Yousef Bader MD
EMO‐GVM Centro Cuore Columbus,
Cardiovascular Center, Tufts Medical Center, Milan, Italy
Boston, MA, USA
Juan Corral MD
Andreas Baumbach MD Lumen Foundation, Miami, FL, USA
Bristol Heart Institute, Bristol, UK
Suzanne de Waha MD
Neeraj Bhalla MD University Heart Center Luebeck,
University Hospital Schleswig‐Holstein,
Department at BLK Super Speciality
Luebeck, Germany
Hospital, New Delhi
Landy Luna Diaz MD
Freddy Bojanini MD
Lumen Foundation, Miami, FL, USA
Lumen Foundation, Miami, FL, USA
Daniela Parra Dunoyer MD
Roberto Vieira Botelho MD PhD
Lumen Foundation, Miami, FL, USA
Eurolatino Medical Research, Lumen
Foundation, Miami, FL, USA Jose Escabi‐Mendoza MD FACC
Cardiac Care Unit and Chest Pain Center,
Estefania Calle Botero MD
VA Caribbean Healthcare System, San Juan,
Lumen Foundation, Miami, FL, USA Puerto Rico, USA
x List of Contributors
Denis Fabiano de Souza RN Thomas W. Johnson BSc MBBS MD FRCP
Research Nurse, Eurolatino Medical Bristol Heart Institute, Bristol, UK
Research, USA
Navin K. Kapur MD
James J. Ferguson III MD
Cardiovascular Center, Tufts Medical Center,
St Luke’s Episcopal Hospital, Boston, MA, USA
Texas, USA
Sasko Kedev MD PhD FESC FACC
Wladimir Fernandes de Rezende MBA
Medical Faculty, Ss Cyril and Methodius
Dax Tecnologia da Informação, Brasilão University, and Director, University Clinic of
Cardiology, Skopje, Macedonia
Francisco Fernandéz MBA
CIO ITMS do Brasil Julius Cezar Q. Ladeira DDS MSc
ITMS do Brasil
Alexandra Ferré MD
Lumen Foundation, Miami, FL, USA David C. Lange MD
Cedars‐Sinai Heart Institute, Los Angeles,
Francesco Giannini MD
CA, USA
Interventional Cardiology Unit,
San Raffaele Scientific Institute, Milan, Italy
Fernando Lapetina‐Irizarry MD FACC
Cardiology Department, Pavia Hospital
Juliana Giraldo MD
Santurce, San Juan, Puerto Rico, USA
Lumen Foundation, Miami, FL, USA
David M. Larson MD
Cindy L. Grines MD
Minneapolis Heart Institute, Minneapolis,
Detroit Medical Center, Heart Hospital,
MN, USA
Detroit, MI, USA
Azeem Latib MD
Timothy D. Henry MD
San Raffaele Scientific Institute, Milan,
Cedars‐Sinai Heart Institute, Los Angeles,
Italy; Interventional Cardiology Unit,
CA, USA
EMO‐GVM Centro Cuore Columbus,
Gerd Heusch MD FACC FESC FRCP Milan, Italy
Institute for Pathophysiology, West German
Michel Le May MD
Heart and Vascular Centre Essen, University
of Essen Medical School, Essen, Germany Director of the Coronary Care Unit, and
Director of the University of Ottawa Heart
David Hildebrandt RN Institute Regional STEMI Program, Ontario,
Cedars‐Sinai Heart Institute, Los Angeles, Canada
CA, USA
Joshua PY Loh MD
Yong Huo MD Consultant at the National University
Peking University First Hospital, Beijing, China Heart Centre, Singapore, and an Assistant
Professor at the Yong Loo Lin School of
David G. Iosseliani MD FACC FESC Medicine, Singapore
Moscow City Center of Interventional
Cindy Manotas MD
Cardioangiology, Moscow, Russian
Federation Lumen Foundation, Miami, FL, USA
List of Contributors xi
Sameer Mehta MD FACC MBA Daniel Rodriguez MD
University of Miami Miller School of Medicine, Lumen Foundation, Miami, FL, USA
and Lumen Foundation, Miami, FL, USA
Orlando Rodríguez‐Vilá MD MMS FACC FSCAI
Nestor Mercado MD Cardiac Catheterization Laboratories, and
Detroit Medical Center, Heart Hospital, Associate Chief of Medicine, VA Caribbean
Detroit, MI, USA Healthcare System, San Juan, Puerto Rico,
USA
Isaac Yepes Moreno MD
Ivan Rokos MD
Lumen Foundation, Miami, FL, USA
UCLA, California, USA
Sebastián Moreno MD
Neil Ruparelia PhD MRCP
Lumen Foundation, Miami, FL, USA
San Raffaele Scientific Institute, Milan, Italy;
Ajit S. Mullasari MD Imperial College, London, UK; EMO‐GVM
Centro Cuore Columbus, Milan, Italy
Madras Medical Mission, Chennai, India
Roopa Salwan MD
Daniella Nacad MD
Cardiology and Interventional Cardiology,
Lumen Foundation, Miami, FL, USA
Max Super Speciality Hospital‐Saket,
Delhi, India
Estefania Oliveros MD
Lumen Foundation, Miami, FL, USA
Márcio Sanches MD
ITMS do Brasil
Samir Pancholy MD FACC FSCAI
Wright Center for Graduate Medical
Theodore L. Schreiber MD
Education, Commonwealth Medical College,
Detroit Medical Center, Heart Hospital,
Scranton, PA, USA
Detroit, MI, USA
Tejas Patel MD DM FACC FESC FSCAI
Michael Schweitzer MD
Apex Heart Institute, Ahmedabad, Gujarat,
Lumen Foundation, Miami, FL, USA
India
Sanjay Shah MD DM
Marco Perin MD
Apex Heart Institute, Ahmedabad, Gujarat,
Lumen Foundation, Miami, FL, USA
India
Carlos Otávio Lara Pinheiro BSc
Holger Thiele MD
Dax Tecnologia da Informação, Brasilão
University Heart Center Luebeck, University
Maria Teresa Bedoya Reina MD Hospital Schleswig‐Holstein, Luebeck,
Germany
Lumen Foundation, Miami, FL, USA
Sergio Reyes MD Maria Botero Urrea MD
Lumen Foundation, Miami, FL, USA Lumen Foundation, Miami, FL, USA
Olga Reynbakh MD Alicia Henao Velasquez MD
Lumen Foundation, Miami, FL, USA Lumen Foundation, Miami, FL, USA
xii List of Contributors
Vincenzo Vizzi MD Yan Zhang MD
Bristol Heart Institute, Bristol, United Kingdom Peking University First Hospital, Beijing, China
Tracy Zhang BS
Lumen Foundation, Miami, FL, USA
