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Lifestyle Changes and HDL Benjamin Ansell, MD FACC, FACP, FNLA Professor of Medicine UCLA School of Medicine Los Angeles, CA wwwwww..lliippiidd..oorrgg Select Lifestyle Interventions and HDL‐C Therapeutic Intervention Increase in HDL‐C Aerobic exercise 5‐10% Tobacco cessation 5‐10% Weight loss 0.35 mg/dL per kg weight lost Alcohol consumption 5‐15% Dietary factors (n‐3, n‐6 PUFA, MUFA) 0‐5% PUFA = polyunsaturated fatty acids MUFA = monounsaturated fatty acids Singh IM, Shishehbor MH, Ansell BJ. JAMA 2007;298:786‐798. wwwwww..lliippiidd..oorrgg Reverse Cholesterol Transport and HDL Metabolism: Lipid Efflux Singh IM, Shishehbor MH, Ansell BJ. JAMA 2007;298:786‐798. wwwwww..lliippiidd..oorrgg Reverse Cholesterol Transport and HDL Metabolism: Lipid Efflux Singh IM, Shishehbor MH, Ansell BJ. JAMA 2007;298:786‐798. wwwwww..lliippiidd..oorrgg Reverse Cholesterol Transport and HDL Metabolism: Lipid Efflux Singh IM, Shishehbor MH, Ansell BJ. JAMA 2007;298:786‐798. wwwwww..lliippiidd..oorrgg Reverse Cholesterol Transport and HDL Metabolism: Lipid Efflux Singh IM, Shishehbor MH, Ansell BJ. JAMA 2007;298:786‐798. wwwwww..lliippiidd..oorrgg Reverse Cholesterol Transport and HDL Metabolism: Cholesterol Uptake Singh IM, Shishehbor MH, Ansell BJ. JAMA 2007;298:786‐798. wwwwww..lliippiidd..oorrgg Reverse Cholesterol Transport and HDL Metabolism: Cholesterol Uptake Singh IM, Shishehbor MH, Ansell BJ. JAMA 2007;298:786‐798. wwwwww..lliippiidd..oorrgg Exercise and HDL‐C • Frequent aerobic exercise: ↑HDL‐C by 5% as ˜ early as 2 months from start of regular exercise in sedentary, otherwise healthy people. • To increase HDL‐C levels optimally: – 5 x 30‐minutes brisk aerobic exercise/week – Total duration of exercise >120 minutes per week is strongest determinant of increased HDL‐C levels. Singh IM, Shishehbor MH, Ansell BJ. JAMA 2007;298:786‐798. wwwwww..lliippiidd..oorrgg Exercise and HDL‐C: Clinical Trials Kodama S et al. Arch Intern Med. 2007;167:999‐1008. wwwwww..lliippiidd..oorrgg

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www.lipid.org. Lifestyle Changes and HDL. Benjamin Ansell, MD FACC, FACP, FNLA. Professor of Medicine. UCLA School of Medicine. Los Angeles

Lifestyle Changes and HDL PDF

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www.lipid.org. Lifestyle Changes and HDL. Benjamin Ansell, MD FACC, FACP, FNLA. Professor of Medicine. UCLA School of Medicine. Los Angeles

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Author:	Unknown
Publication Year:	2013
Pages:	41
Language:	English
File Size:	0.86
Format:	PDF
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