Table Of ContentLEWIS’S CHILD
AND ADOLESCENT
PSYCHIATRY
A Comprehensive Textbook
FIFTH EDITION
Editors
Andrés Martin, MD, MPH
Riva Ariella Ritvo Professor
Child Study Center
Yale School of Medicine
New Haven, Connecticut
Michael H. Bloch, MD, MS
Associate Professor
Child Study Center
Yale School of Medicine
New Haven, Connecticut
Fred R. Volkmar, MD
Irving B. Harris Professor of Child Psychiatry, Pediatrics, and Psychology
Child Study Center
Yale School of Medicine
New Haven, Connecticut
Acquisitions Editor: Chris Teja
Product Development Editor: Ashley Fischer
Editorial Coordinator: David Murphy
Editorial Assistant: Brian Convery
Marketing Manager: Rachel Mante Leung
Production Project Manager: David Saltzberg
Design Coordinator: Elaine Kasmer
Manufacturing Coordinator: Beth Welsh
Prepress Vendor: Aptara, Inc.
5th edition
Copyright © 2018 Wolters Kluwer.
Copyright © 2007 by LIPPINCOTT WILLIAMS & WILKINS, a Wolters Kluwer
business. Copyright © 2002 by Lippincott Williams & Wilkins. Copyright © 1996
and 1991 by Williams & Wilkins. All rights reserved. This book is protected by
copyright. No part of this book may be reproduced or transmitted in any form or by
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Library of Congress Cataloging-in-Publication Data
Names: Martin, Andrés, editor. | Volkmar, Fred R., editor. | Bloch, Michael (Michael
Howard), editor.
Title: Lewis’s child and adolescent psychiatry : a comprehensive textbook / editors,
Andrés Martin, Fred R. Volkmar, Michael Bloch.
Other titles: Child and adolescent psychiatry
Description: Fifth edition. | Philadelphia : Wolters Kluwer, [2018] | Includes
bibliographical references.
Identifiers: LCCN 2017025399 | ISBN 9781496396587
Subjects: | MESH: Mental Disorders | Infant | Child | Adolescent
Classification: LCC RJ131 | NLM WS 350 | DDC 618.92/89–dc23
LC record available at https://lccn.loc.gov/2017025399
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professionals’ examination of each patient and consideration of, among other things,
age, weight, gender, current or prior medical conditions, medication history,
laboratory data and other factors unique to the patient. The publisher does not
provide medical advice or guidance and this work is merely a reference tool.
Healthcare professionals, and not the publisher, are solely responsible for the use of
this work including all medical judgments and for any resulting diagnosis and
treatments.
Given continuous, rapid advances in medical science and health information,
independent professional verification of medical diagnoses, indications, appropriate
pharmaceutical selections and dosages, and treatment options should be made and
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LWW.com
We dedicate this book
To our wives:
Rebecca, Angie, and Lisa;
To our children:
Max, Ariela, Gabriela, and Jacob Donald; Rachel, Sam, and Tom; and
Lucy and Emily;
To the teachers and mentors from whom we have received so much;
To the patients, families, students and colleagues to whom we hope in
some measure to have given back;
To all those dedicated to child and adolescent mental health, working each
day to make a difference.
As editors we are proud to donate our royalty proceeds, in loving memory
of our teacher and friend, the late Melvin Lewis, to the Break the Cycle
initiative of the American Academy of Child and Adolescent Psychiatry.
The Academy continues to support efforts in education, training, and
research for the next generation of practitioners, a mission that was near
and dear to Mel.
We ourselves have been the grateful recipients of such support, and are
honored to contribute so that others may benefit like we did.
CONTRIBUTING AUTHORS
Jean A. Adnopoz, MPH
Clinical Professor
Director In-Home Services
Child Study Center
Yale School of Medicine
New Haven, Connecticut
Robert R. Althoff, MD, PhD
Vermont Center for Children, Youth, and Families
University of Vermont College of Medicine/ Fletcher Allen Health Care
Burlington, Vermont
Thomas F. Anders, MD
Distinguished Professor Emeritus
UC Davis School of Medicine
Davis, California
George M. Anderson, PhD
Senior Research Scientist
Child Study Center and the Department of Laboratory Medicine
Yale School of Medicine
New Haven, Connecticut
Adrian Angold, MRCPsych
Professor Emeritus
Department of Psychiatry and Behavioral Sciences
Duke University Medical Center
Durham, North Carolina
Eugene L. Arnold, MD, MEd
Professor Emeritus
Department of Psychiatry and Behavioral Health
Ohio State University
Columbus, Ohio
Peter Ash, MD
Professor and Director
Psychiatry and Law Service
Department of Psychiatry and Behavioral Sciences
Emory University
Atlanta, Georgia
Andrea G. Asnes, MD, MSW
Associate Professor of Pediatrics
Yale School of Medicine
New Haven, Connecticut
David A. Axelson, MD
Professor
Department of Psychiatry and Behavioral Health
The Ohio State University College of Medicine
Chief of Psychiatry and Behavioral Health
Nationwide Children’s Hospital
Columbus, Ohio
Kathleen M.B. Balestracci, PhD, MSW
Assistant Clinical Professor
Child Study Center
Yale School of Medicine
New Haven, Connecticut
Argelinda Baroni, MD
Assistant Professor
The Child Study Center at NYU Langone Medical Center
New York, New York
Steven J. Barreto, PhD
Clinical Associate Professor
Warren Alpert Medical School of Brown University
Department of Psychiatry and Behavioral Medicine
Bradley Hospital
East Providence, Rhode Island
Karen Bearss, PhD
Assistant Professor
Marcus Autism Center
Department of Pediatrics
Emory University
Atlanta, Georgia
Myron L. Belfer, MD, MPA
Professor of Psychiatry
Harvard Medical School
Senior Associate in Psychiatry
Boston Children’s Hospital
Boston, Massachusetts
Eugene V. Beresin, MD, MA
Executive Director
The Clay Center for Young Healthy Minds
Senior Educator in Child and Adolescent Psychiatry
Massachusetts General Hospital
Professor of Psychiatry
Harvard Medical School
Boston, Massachusetts
Chad Beyer
Stellenbosch University Stellenbosch
South Africa
Boris Birmaher, MD
Professor of Psychiatry
Endowed Chair in Bipolar Disorder
University of Pittsburgh Medical Center
Western Psychiatric Institute and Clinic
Pittsburgh, Pennsylvania
Joseph C. Blader, PhD
Meadows Foundation and Semp Russ Professor of Child Psychiatry
Departments of Psychiatry and Pediatrics
University of Texas Health Science Center at San Antonio
San Antonio, Texas
Efrain Bleiberg, MD
Professor
Menninger Department of Psychiatry and Behavioral Sciences
Baylor College of Medicine
Houston, Texas
Michael H. Bloch, MD, MS
Associate Professor
Child Study Center
Yale School of Medicine
New Haven, Connecticut
John R. Boekamp, PhD
Department of Psychiatry and Human Behavior
Alpert Medical School of Brown University
Emma Pendleton Bradley Hospital
East Providence, Rhode Island
Jeff Q. Bostic, MD, EdD
Associate Clinical Professor
Department of Psychiatry
Harvard Medical School
Boston, Massachusetts
Eric N. Boyum, MD
Adjunct Clinical Assistant Professor
Child and Adolescent Psychiatry
University of Iowa Hospitals and Clinics
Iowa City, Iowa
David A. Brent, MD
Academic Chief
Child and Adolescent Psychiatry
Western Psychiatric Institute and Clinic
University of Pittsburgh Medical Center
Professor of Psychiatry, Epidemiology, Pediatrics, and Clinical Translational Science
Department of Psychiatry
University of Pittsburgh School of Medicine
Pittsburgh, Pennsylvania
Rachel Margaret Ann Brown, MBBS, MPhil
Professor of Clinical Psychiatry
Department of Psychiatry
University of Missouri School of Medicine
Columbia, Missouri
Catherine Brownstein, MPH, PhD
Division of Genetics and Genomics
Boston Children’s Hospital
Instructor, Department of Pediatrics
Harvard Medical School
Scientific Director
Manton Center for Orphan Disease Research
Boston, Massachusetts
T. Lindsey Burrell, PhD
Assistant Professor
Marcus Autism Center
Department of Pediatrics
Children’s Healthcare of Atlanta
Emory University
Atlanta, Georgia
John V. Campo, MD
Sinsabaugh Professor and Chair
Department of Psychiatry and Behavioral Health
The Ohio State University
Wexner Medical Center
Columbus, Ohio
Laurie Cardona, PsyD
Assistant Professor
Child Study Center
Yale School of Medicine
New Haven, Connecticut
Lee Combrinck-Graham, MD
Medical Director
LifeBridge Community Services
Bridgeport, Connecticut
Kathryn A. Coniglio, BA
Clinical Research Coordinator
Department of Psychiatry
Massachusetts General Hospital
Boston, Massachusetts
Daniel F. Connor, MD
Lockean Distinguished Professor of Psychiatry and Chief, Division of Child and Adolescent Psychiatry
University of Connecticut School of Medicine
Farmington, Connecticut
Kate L. Conover, BA
SDSU-UC San Diego Joint Doctoral Program in Clinical Psychology
San Diego, California
Elizabeth Jane Costello, PhD
Professor
Department of Psychiatry and Behavioral Sciences
Duke University School of Medicine
Durham, North Carolina
Peter T. Daniolos, MD
Clinical Professor and Training Director
Child and Adolescent Psychiatry
University of Iowa Hospitals and Clinics
Iowa City, Iowa
Mary Lynn Dell, MD, DMin
Professor of Clinical Psychiatry and Pediatrics
Nationwide Children’s Hospital and the Ohio State University
Columbus, Ohio
Annelou L. C. de Vries, MD, PhD
Department of Child and Adolescent Psychiatry
Center for Expertise on Gender Dysphoria
VU University Medical Center
Amsterdam, The Netherlands
Deborah Blythe Doroshow, MD, PhD
Section of the History of Medicine
Yale School of Medicine
New Haven, Connecticut
Jana K. Dreyzehner, MD
Child Psychiatrist
Tennessee School for the Deaf
Knoxville, Tennessee
Elisabeth M. Dykens, PhD
Professor
Psychology and Human Development
Vanderbilt University
Nashville, Tennessee
