Leukocyte Typing II: Volume 1: Human T Lymphocytes

537 Pages·1986·31.191 MB·English

by  Barton F. Haynes (auth.), Ellis L. Reinherz M.D., Barton F. Haynes M.D., Lee M. Nadler M.D., Irwin D. Bernstein M.D. (eds.)

Leukocyte Typing II
VOLUME 1
Human T Lymphocytes
Leukocyte Typing II
Volume 1 Human T Lymphocytes
Volume 2 Human B Lymphocytes
Volume 3 Human Myeloid and Hematopoietic Cells
Leukocyte Typing II
VOLUME 1
Human T Lymphocytes
Edited by
Ellis L. Reinherz Barton F. Haynes
Lee M. Nadler Irwin D. Bernstein
With 123 Illustrations
Springer-Verlag
New York Berlin Heidelberg Tokyo
EUis L. Reinherz, M.D., Division of Tumor Immunology, Dana-Farber Cancer
Institute, Boston, MA 021I5 U.S.A.
Barton F. Haynes, M.D., Department of Medicine, Duke University School of
Medicine, Durham, NC 27710 U.S.A.
Lee M. Nadler, M.D., Division of Tumor Immunology, Dana-Farber Cancer
Institute, Boston, MA 02115 U.S.A.
Irwin D. Bernstein, M.D., Program in Pediatric Oncology, Fred Hutchinson Can
cer Research Center, Seattle, WA 98104 U.S.A.
Library of Congress Cataloging in Publication Data
Main entry under title:
Leukocyte typing II.
Papers presented at the Second International
Workshop on Human Leukocyte Differentiation Antigens,
held in Boston, Sept. 17-20, 1984.
Includes bibliographies and indexes.
Contents: v. 1. Human T lymphocytes-v. 2. Human
B lymphocytes-v. 3. Human myeloid and hematopoietic
cells.
1. Leucocytes-Classification-Congresses.
2. Histocompatibility testing-Congresses. 3. Tissue
specific antigens-Analysis-Congresses. I. Reinherz,
Ellis L. II. International Workshop on Human
Leukocyte Differentiation Antigens (2nd: 1984 : Boston,
Mass.) III. Title: Leukocyte typing 2. IV. Title:
Leukocyte typing two.
QRI85.8.L48L48 1985 616.07'9 85-22229
© 1986 by Springer-Verlag New York Inc.
Softcover reprint of the hardcover 1st edition 1986
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ISBN-13:978-I-46I3-8589-9/1986 $0.00 + .20
Typeset by Bi-Comp Inc., York, Pennsylvania.
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ISBN -13: 978-1-4613-8589-9 e-ISBN -13: 978-1-4613-8587-5
DOl: 10.1007/978-1-4613-8587-5
Preface
The Second International Workshop on Human Leukocyte Differentia
tion Antigens was held in Boston, September 17-20, 1984. More than 350
people interested in leukocyte differentiation agreed to exchange reagents
and participate in this joint venture. All in all, in excess of 400 antibodies
directed against surface structures on T lymphocytes, B lymphocytes,
and myeloid-hematopoietic stem cells were characterized. Because of the
enormous quantity of serologic, biochemical, and functional data, Leuko
cyte Typing II has been divided into three volumes.
These books represent the written results of workshop participants.
They should be helpful to both researchers and clinicians involved in
scientific endeavors dealing with these broad fields of immunobiology. To
those who delve into the various sections of the volumes, it will become
evident that the work speaks for itself.
I am deeply indebted to the section editors, Barton F. Haynes, Volume
1, Human T Lymphocytes, Lee M. Nadler, Volume 2, Human B Lympho
cytes, and Irwin D. Bernstein, Volume 3, Human Myeloid and Hemato
poietic Cells for their major contributions in planning, executing, and
summarizing the workshop, as well as council members John Hansen,
Alain Bernard, Laurence Boumsell, Walter Knapp, Andrew McMichael,
Cesar Milstein, and Stuart F. Schlossman. I would also like to thank the
National Institutes of Health, World Health Organization, and Interna
tional Union of Immunological Societies for making this meeting possible.
Needless to say, I am most grateful to all of my colleagues who contrib
uted to this effort and helped to accelerate the characterization of human
immunobiology through their endeavors.
Ellis L. Reinherz. M.D.
Contents
I. Introduction
1. Summary of T Cell Studies Performed during the Second
International Workshop and Conference on Human
Leukocyte Differentiation Antigens B.F. Haynes 3
II. Functional Studies
2. Binding and Functional Analysis of the Workshop T Cell
Specific Set of Monoclonal Antibodies F.M. Gotch,
N. Carter, S. Ellis, P. McShane, 1. Heyman, M. Palmer,
D. W. Dongworth, A. Bewick, P.l. Morris,
A.l. McMichael 31
3. Functional Studies Performed with the Second Interna
tional Workshop T Cell Panel of Monoclonal Antibodies
D. Charmot, D. Olive, P. Dubreuil, M. Ragueneau,
C. Mawas 45
4. The Epitopic Dissection of the CD2 Defined Molecule:
Relationship of the Second Workshop Antibodies in Terms
of Reactivities with Leukocytes, Rosette Blocking Proper
ties, Induction of Positive Modulation of the Molecule,
and Triggering T Cell Activation A. Bernard, P. Brottier,
E. Georget, V. Lepage, L. Boumsell 53
5. Monoclonal Antibodies as Probes to Define Critical
Surface Structures Involved in T Cell Activation
S.C. Meuer, T.H. Hutteroth,
K.H. Meyer zum Biischenfelde 67
6. The Development of Monoclonal Antibodies against
Human Immunoregulatory T Cell Subsets: The Isolation of
viii Contents
Human Suppressor Inducer T Cell Subset C. Morimoto,
N.L. Letvin, S.F. Schlossman 79
7. Lectin Activation Induces T4, T8 Coexpression on
Peripheral Blood T Cells M.L. Blue, I.F. Daley,
H. Levine, S.F. Schlossman 89
8. Analysis of the Ontogeny and Function of Human Helper
T Cell Subpopulations L.T. Clement, M.D. Cooper,
T.F. Tedder 101
9. Effects of Workshop Monoclonal Antibodies on the
Cytolytic Activity of Alloreactive CD4-Positive T Cell
Clones N. Flomenberg, B. Dupont, R. W. Knowles 111
10. Effects of the Workshop Anti-T Cell Monoclonal Antibod
ies on Lymphocyte Proliferative and Cytotoxic Func-
tions G. Gorog, G. Batory, T. Laskay, G.G. Petranyi 123
11. T Cell Activation by CD3 Antibodies R. Kurrle,
W. Seyfert, A. Trautwein, F.R. Seiler 137
12. Studies of T Cell Proliferation Induced by Monoclonal
Antibodies of the Second International Workshop
P.J. Martin, I.A. Ledbetter, P.G. Beatty, E.A. Clarke,
I.A. Hansen 147
13. Phorbol Ester Induces Changes in the Pattern of Cell
Surface Molecules Involved in CTL-Target Cell
Interaction I. Ando, D.H. Crawford, P.c.L. Beverley 157
14. Analysis of the Monocyte-T Cell Interaction Required for
Induction of T Cell Proliferation by Anti-T3 Antibodies
L.T. Clement 163
15. Evaluation of the T Cell Workshop Monoclonal Antibodies
in In Vitro Lymphocyte Proliferation Assays
N.L. von leney, K. Olas, W. Knapp 173
16. The Influence of the Workshop Monoclonal Antibodies on
CML, AgTR, PLT, ADCC, and NK Cell Activity. Func
tional Studies with Workshop Antibodies F. Koning,
M. Kardol, I. van der Poel, A. Termijtelen, E. Goulmy,
T. Ottenhoff, E. Blokland, D. Elferink, I. Pool,
S. Naipal-van den Berge, H. Bruning 189
17. The Influence of Anti-T Cell Monoclonal Antibodies on
Calcium Mobilization: Investigation of Workshop Antibod-
ies K. O'Flynn, P.c.L. Beverley, D.C. Linch 205
Contents ix
18. T Cell-Dependent Immunoglobulin Synthesis in the Human
System. Studies with T Cell-Specific Monoclonal
Antibodies F. Miedema, F.G. Terpstra, C.J.M. Melief 213
19. Monoclonal Antibodies Recognizing the T3/Leu4 T Cell
Differentiation Antigen Induce Suppressor Cells
J.E. Kunicka, C.D. Platsoucas 223
20. Modulation of T Cell Functions by Monoclonal "Pan T
Cell" Antibodies Not Directed against the T Cell Receptor
Complex P. Rieber, G. Rank, S. Wirth, M. Wilhelm,
E. Kopp, G. Riethmuller 233
21. Determinant Heterogeneity of CD5, CD8, and CD4 Anti
gen Molecules As Defined by Monoclonal Antibodies
T. Takei, Y. Ishii, S. Kon, J. Fujimoto, K. Kikuchi 243
III. Biochemical Studies
22. Immunochemical Analysis of the T Cell-Specific
Antigens R. W. Knowles 259
23. Epitopic Groups of CD1 Molecules L. Boumsell,
M. Amiot, B. Raynal, V. Gay-Belli/e, B. Ca illou ,
A. Bernard 289
24. Comparison of the CD7 (3Al) Group of T Cell Workshop
Antibodies T.J. Palker, R.M. Scearce, L.L. Hensley,
W. Ho, B.F. Haynes 303
IV. Phenotypic Characterization of T Cell Leukemias and
Lymphomas
25. Study on Human T Leukemia-Lymphoma Cell Lines by
the Second International Workshop Monoclonal Antibod
ies of the T Cell Protocol J. Minowada, M. Menon,
H.G. Drexler, S. Gignac, B. Misra, L. Skowron 317
26. Expression of T Cell-Related Antigens on Cells from the
Myelo-Monocytic Lineage P. Dubreuil, P. Mannoni,
D. Olive, B. Winkler-Lowen, C. Mawas 335
27. Phenotype of Hodgkin Cells. Expression of the Tac
Antigen and Other Determinants K.J. Bross,
R. Andreesen, T. Monnheimer, J. Osterholz, G. W. Lohr 343
28. The Diversity of T Cell Activation Antigens. Serological
Analysis Including Their Expression on Non-T Acute
x Contents
Lymphoblastic Leukemia Cells and B Cell Lines Derived
from Adult T Cell Leukemia Patients Y. Morishima,
T. Noumi, K. Ohya, S. Mimami, M. Okumura, S. Mizuno,
R. Ohno, K. Miyamoto 351
29. Expression Profiles of T Cell Associated Antigens on
Adult T Cell Leukemia Cells: Results of a Workshop
Study K. Sagawa, S. Hagiwara, K. Yasuda,
M.M. Yokoyama 361
V. Phylogenetic Studies Using Anti-T Cell Antibodies
30. The Phylogeny of T Cell Antigens M. Jonker,
F.J.M. Nooij 373
31. Conserved T Lymphocyte-Specific Antigens in Primates
N.L. Letvin 389
VI. Study of Anti-T Cell Antibodies on Frozen Tissue Sections
of Human Tissue
32. Ontogeny of Human T Cell Antigens D.F. Lobach,
L.L. Hensley, W. Ho, B.F. Haynes 397
33. Cross-reactivity of Anti-lymphocyte Monoclonal Antibod-
ies on Human Skin Components J. Brochier, D. Schmitt 407
VII. Study of Antibodies Reactive with Antigens of
Activated T Cells
34. Flow Cytometric Analysis of the Antigens Expressed by
Peripheral Blood Lymphocytes Stimulated by Phyto
hemagglutinin Using the Workshop T Cell Panel and
Selected Band M Cell Panel Monoclonal Antibodies
D. Olive, P. Dubreuil, C. Mawas, P. Mannoni 417
35. Regulation of Activation and Proliferation in T Cells
P.C.L. Beverley, K. O'Flynn, D.L. Wallace, J.R. Lamb,
A. W. Boylston, D.C. Linch 427
36. Phenotypic Analysis of Activation Antigens on Mitogen
stimulated T Cells Utilizing Monoclonal Antibodies
T. Umiel, E. Saltz-Tal 441
37. T-Activation Antigens: Kinetics of Appearance and
Effect on Cell Proliferation Studied with Monoclonal
Antibodies L. Del Vecchio, M. De Felice, M.C. Turco,
M. Maio, E. Pace, C. Lo Pardo, C. Vacca, S. Venuta,
S. Zappacosta 453
Contents xi
VIII. Study of T Cell Leukemia-Associated Antigens
38. Antibody 3-40 Binds to Keratin and Vimentin Intermediate
Filaments A.J. Laster, T.J. Palker, E.A. Harden, W. Ho,
K. Naito, B. DuPont, B.F. Haynes 465
IX. Other Types of Studies and Description of New T Cell
Markers
39. Screening of Monoclonal Antibodies against T Cell Differ-
entiation Antigens Using Transfectants or Somatic Cell
Hybrids R. Ueda, N. Emi, I. Tsuge, K. Nishida,
K.R. Utsumi, S. Takamoto, T. Maruyama, K. Ota,
T. Takahashi 477
40. Association of IL-2 Production with the Expression of
Dipeptidyl Peptidase IV (DPIV) on Human T Lympho-
cytes W. Scholz, A.C. Feller, A.J. Ulmer, H.D. Flad 489
41. A Novel Disulfide-Linked Cell Surface Molecule Present
on Resting and Activated Human T Lymphocytes
R.D. Bigler, N. Chiorazzi 503
42. T14, A Non-modulating 150-Kd T Cell Surface Antigen
H. Stockinger, O. Majdic, K. Liszka, U. Koller,
W. Holter, C. Peschel, P. Bettelheim, H. Gisslinger,
W. Knapp 513
43. Specific Membrane Lectin of Human T Suppressor Cells
C. Kieda, M. Monsigny 531
Index 537