Lactic Acid Bacteria: Genetics, Metabolism and Applications: Proceedings of the Sixth Symposium on lactic acid bacteria: genetics, metabolism and applications, 19–23 September 1999, Veldhoven, The Netherlands

398 Pages·1999·60.71 MB·English

by  Gerard Venema, Jan Kok, Douwe van Sinderen (auth.), W. N. Konings, O. P. Kuipers, J. H. J. Huis In ’t Veld (eds.)

LACTIC ACID BACTERIA: GENETICS, METABOLISM AND APPLICATIONS
Lactic Acid Bacteria: Genetics,
Metabolism and Applications
Proceedings of the Sixth Symposium on lactic acid bacteria: genetics, metabolism and
applications, 19-23 September 1999, Veldhoven, The Netherlands
Edited by
W.N. KONINGS
University of Groningen,
The Netherlands
O.P. KUIPERS
University of Groningen,
The Netherlands
and
J.R.J. RUIS IN 'T VELD
Utrecht University,
The Netherlands
Reprinted from Antonie van Leeuwenhoek, Volume 76, Nos. 1-4, 1999
Springer-Science+Business Media, B. V.
A C.I.P. Catalogue record for this book is available from the Library of Congress.
ISBN 978-90-481-5312-1 ISBN 978-94-017-2027-4 (eBook)
DOl 10.1007/978-94-017-2027-4
Printed on acid-free paper
All Rights reserved
© 1999 Springer Science+Business Media Dordrecht
Originally published by K1uwer Academic Publishers in 1999
Softcover reprint of the hardcover 1s t edition 1999
No part of the material protected by this copyright notice may be reproduced
or utilized in any form or by any means, electronic or mechanical,
including photocopying, recording or by any information storage and
retrieval system, without written permission from the copyright owner.
Table of Contents
Editorial 1
From DNA sequence to application: possibilities and complications 3
G. Venema, J. Kok, D. van Sinderen
GENETICS
Low-redundancy sequencing of the entire Lactococcus lactis IL 1403 genome 27
A. Bolotin, S. Mauger, K. Malarme, S.D. Ehrlich, A. Sorokin
Group II introns and expression of conjugative transfer functions in lactic acid bacteria 77
G.M. Dunny, L.L. McKay
Bacteriophage defence systems in lactic acid bacteria
A. Forde, G.F. Fitzgerald 89
Acquired antibiotic resistance in lactic acid bacteria from food
M. Teuber, L. Meile, F. Schwarz 115
Multi-domain, cell-envelope proteinases of lactic acid bacteria 139
R.J. Siezen
METABOLISM
The biosynthesis and functionality of the cell-wall of lactic acid bacteria 159
J. Delcour, T. Ferain, M. Deghorain, E. Palumbo, P. Hols
Bacteriocins: mechanism of membrane insertion and pore formation 185
G.N. Moll, WN. Konings, A.J.M. Driessen
Intestinal microflora and the interaction with immunocompetent cells 199
S. Blum, S. Alvarez, D. Haller, P. Perez, E.J. Schiffrin
Bioactive peptides encrypted in milk proteins: proteolytic activation and thropho- 207
functional properties
H. Meisel, W Bockelmann
Peptidases and amino acid catabolism in lactic acid bacteria 217
J.E. Christensen, E.G. Dudley, JA Pederson, J.L. Steele
Sulfur metabolism in bacteria associated with cheese 247
B. Weimer, K. Seefeldt, B. Dias
APPLICATIONS
Analysis of the intestinal microflora: a renaissance 265
G.W Tannock
vi
Probiotics: from myth to reality. Demonstration of functionality in animal models of 279
disease and in human clinical trials
C. Dunne, L. Murphy, S. Flynn, L. O'Mahony, S. O'Halioran, M. Feeney, D. Morrissey, G.
Thornton, G. Fitzgerald, C. Daly, B. Kiely, E.M.M. Quigley, G.C. O'Sullivan, F. Shanahan, J.K.
Collins
Bringing a probiotic-containing functional food to the market: microbiological, product, 293
regulatory and labeling issues
M.E. Sanders, J. Huis in 't Veld
Lactic acid bacteria in the quality improvement and depreciation of wine 317
A. Lonvaud-Funel
SHORT LECTURES
Overview on applications for bacteriocin-producing lactic acid bacteria and their bac- 335
teriocins
J.B. Luchansky
Developing applications for lactococcal bacteriocins 337
R.P Ross, M. Galvin, O. McAuliffe, S.M. Morgan, M.P Ryan, D.P Twomey, WJ. Meaney,
C.HiII
Multidrug resistance in lactic acid bacteria: molecular mechanisms and clinical relev- 347
ance
H.W van Veen, A. Margolies, M. Putman, K. Sakamoto, WN. Konings
DNA-mircoarrays and food-biotechnology
O.P Kuipers, A. de Jong, S. Holsappel, S. Bron, J. Kok, L.W Hamoen 353
Exopotysaccharides produced by Lactococcus iactis: from genetic engineering to 357
improved rheological properties?
M. Kleerebezem, R. van Kranenburg, R. Tuinier, I.C. Boels, P Zoon, E. Looijesteijn,
J. Hugenholtz, WM. de Vos
Anchoring of proteins to lactic acid bacteria 367
K. Leenhouts, G. Buist, J. Kok
Applications of phage resistance in lactic acid bacteria 377
S. Moineau
Immunomodulatory function of lactic acid bacteria 383
H. Yasui, K. Shida, T. Matsuzaki, T. Yokokura
The role of lactic acid bacteria in colon cancer prevention: mechanistic considerations 391
K. Hirayama, J. Rafter
Lactic acid food fermentation in tropical climates 395
M.J.R. Nout, PK. Sarkar
Non-dairy lactic fermentations: the cereal world 403
R.F. Vogel, R. Knorr, M.RA MOiler, U. Steudel, M.G. Ganzle, M.A. Ehrmann
Antonie van Leeuwenhoek 76: 1, 1999.
1
© 1999 Kluwer Academic Publishers.
Editorial
The Sixth Symposium on Lactic Acid Bacteria
In 1981 the initiative was taken to organize a sym- genomics of the unknown genes will be one research
posium on Lactic Acid Bacteria. This symposium line, a detailed analysis of the metabolic pathways
would offer the international scientific community another obvious offspring of this achievement. The
involved in research on Lactic Acid Bacteria the op- relative simplicity of LABs and the enormous amount
portunity to present progress reports to the experts in of information already available will be very helpful
the field and to offer a platform for scientific interac- in the construction of 'in silico' cells.
tions. The first meeting in Wageningen in 1983 was But this will be by no means the only challenge
a great success. Now in hindsight we may conclude for future research. Among others the role of LABs
that in 1983 the research on LAB was still in a lag- in probiotics and in food manufacturing will remain
phase and has developed since exponentially. Right important topics for future research. It is a pleasure
now in 1999 we might actually be in mid-log phase, to work in such a dynamic field of microbiology. The
judging from the excellent and exciting contributions excitement that this research brings to the scientists
presented in this book, by the lecturers of the 6th LAB involved will be transparent for those who read the
symposium, from the progress reports described in the different chapters of this book.
poster abstracts and from the large number of parti-
cipants. Many important aspects of LABs have been W.N. Konings
analyzed especially from a number of Lactococcus University of Groningen, the Netherlands
and Lactobacillus strains. It will take several more
years to study other LABs in similar detail. J.R.J. Ruis in 't Veld
In this book the first complete genome of a Lactic Utrecht University, the Netherlands
Acid Bacterium is presented. The sequencing of the
genomes of several other LABs has started already or O.P. Kuipers
will begin soon. These genome sequences will open University of Groningen, the Netherlands
and stimulate new research area on LAB. Functional
GENETICS
METABOLISM
APPLICATIONS
SHORT LECTURES