Journal of Cellular Neuroscience and Oxidative Stress SUBSCRIPTION ORDER FORM

159 Pages·2015·3.48 MB·English

th
6 World Congress of
Oxidative Stress,
Calcium Signaling and
TRP Channels

24 - 27 May 2016 Isparta / TURKEY
www.cmos.org.tr
Volume 8, Num ber 1, 2016

E-ISSN Number: 214 9-7222 (Online)

Indexing: Google Scholar, Index Copernicus , Chemical Abstracts, Scopus (Elsevier),
EBSCOhost Research Database

EDITOR IN CHIEF AIM AND SCOPES
Mustafa Nazıroğlu, Journal of Cellular Neuroscience and Oxidative Stress
Department of Biophysics and Neurosciences, is an online journal that publishes original research
Medical Faculty, Suleyman Demirel University, articles, reviews and short reviews on the molecular
Isparta, Turkey. basis of biophysical, physiological and
Phone: [phone]. Fax:[phone] pharmacological processes that regulate cellular
E-mail: [email protected] function, and the control or alteration of these
processes by the action of receptors,
Associate Editors neurotransmitters, second messengers, cation,
A. Cihangir Uğuz and Ömer Çelik, anions, drugs or disease.
Department of Biophysics, Medical Faculty,
Suleyman Demirel University, Isparta, Turkey. Areas of particular interest are four topics. They are;
E-mail: [email protected]
A- Ion Channels (Na+- K+ Channels, Cl– channels,
Managing Editors Ca2+ channels, ADP-Ribose and metabolism of NAD+,
Bilal Çiğ and Yener Yazğan
Patch- Clamp applications)
Department of Biophysics, Medical Faculty,

Suleyman Demirel University, Isparta, Turkey.
B- Oxidative Stress (Antioxidant vitamins, antioxidant
E-mail: [email protected]
enzymes, metabolism of nitric oxide, oxidative stress,

biophysics, biochemistry and physiology of free
Editorial Board
oxygen radicals)
Cell Membranes, Ion Channels and Calcium Signaling
Alexei Tepikin, University of Liverpool, UK
Andreas Lückhoff, Aachen University, Germany C- Interaction Between Oxidative Stress and Ion
Channels in Neuroscience
Jose Antonio Pariente, University of Extremadura,
(Effects of the oxidative stress on the activation of
Badajoz, Spain.
the voltage sensitive cation channels, effect of
James W. Putney, Jr. NIEHS, NC, USA.
ADP-Ribose and NAD+ on activation of the cation
Martyn Mahaut Smith, Universtiy of Leicester, UK.
channels which are sensitive to voltage, effect of
Stephan M. Huber, Eberhard-Karls University Tubingen,
the oxidative stress on activation of the TRP
Germany
channels, role of TRPM2 channels in

neurodegenerative diseases such Parkinson’s and
Neuroscience and Cell Signaling
Alzheimer’s diseases)
Abbas Haghparast, Shahid Beheshti University of

Medical Sciences, Tehran, Iran
Denis Rousseau, Science Faculty, Joseph Fourier D- Gene and Oxidative Stress
(Gene abnormalities. Interaction between gene and
University, Grenoble, France
free radicals. Gene anomalies and iron. Role of
Makoto Tominaga, National Institute for Physiological
radiation and cancer on gene polymorphism)
Sciences Okazaki, Japan

Saeed Semnanian, Tarbiat Modares University,
READERSHIP
Tehran, Iran
Biophysics Biochemistry
Suresh Yenugu, Osmania University, Hyderabad, India
Biology Biomedical Engineering
Yasuo Mori, Kyoto University, Kyoto, Japan
Pharmacology PhysiologyGenetics

Cardiology Neurology
Enzymatic Antioxidants
Oncology Psychiatry
Michael Davies, The Heart Research Institute, Sydney,
Neuroscience Neuropharmacology
Australia.

Süleyman Kaplan, Ondokuz Mayıs Univesity, Samsun,
Keywords
Turkey
Ion channels, cell biochemistry, biophysics, calcium
Xingen G. Lei, Cornell University, Ithaca, NY, USA
signaling, cellular function, cellular physiology,
Ozcan Erel, Yıldırım Beyazıt University, Ankara, Turkey.
metabolism, apoptosis, lipid peroxidation, nitric

oxide synthase, ageing, antioxidants, neuropathy,
Nonenzymatic Antioxidants, Nutrition and Melatonin
traumatic brain injury, spinal cord injury, Alzheimer’ s
Ana B. Rodriguez Moratinos, University of
Disease, Parkinson’s Disease.
Extremadura, Badajoz, Spain.
Cem Ekmekcioglu, University of Vienna, Austria.
Peter J. Butterworth, King’s College London, UK
ii 6th World Congress of Oxidative Stress, 24 – 27 May 2016 [ Volume 8, Number 1, 2016 ]
Calcium Signaling and TRP Channels
The abstract of the congress is published in this issue.

th
6 World Congress of
Oxidative Stress,
Calcium Signaling
and TRP Channels
was supported by
The Scientific and
Technological Resarch
Council of Turkey

6th World Congress of Oxidative Stress, 24 – 27 May 2016 [ Volume 8, Number 1, 2016 ] i ii
Calcium Signaling and TRP Channels
th
6 World Congress of Oxidative Stress,

Calcium Signaling and TRP Channels

The congress organization committee wishes thanks to the sponsors below

iv 6th World Congress of Oxidative Stress, 24 – 27 May 2016 [ Volume 8, Number 1, 2016 ]
Calcium Signaling and TRP Channels
th
6 World Congress of Oxidative Stress,

Calcium Signaling a nd TRP Channels

Abstract Book
of
th
6 World Congress of Oxidative Stress,
Calcium Signaling and TRP Channels
24 - 27 May 2016
Isparta, Turkey
with collaboration of
Cellular Neuroscience
and Oxidative Stress Society
and Department of Biophysics,
School of Medicine,
Süleyman Demirel University

6th World Congress of Oxidative Stress, 24 – 27 May 2016 [ Volume 8, Number 1, 2016 ] v
Calcium Signaling and TRP Channels
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6 World Congress of Oxidative Stress,

Calcium Signaling and TRP Channels

___________ [ Organization Committee ] ___________

Congress Honour Committee
Prof. Dr. İlker Hüseyin ÇARIKÇI
Rector
Suleyman Demirel University, Isparta, Turkey

Prof. Dr. Alim KOŞAR
Dean School of Medicine
Suleyman Demirel University, Isparta, Turkey

Organization Committee
Chairman
Prof. Dr. Mustafa NAZIROĞLU
Department of Biophysics, School of Medicine
Suleyman Demirel University, Isparta, Turkey

Prof. Dr. James W. Jr. PUTNEY
1st International Vice Chairman
NIEHS Calcium Regulation Group Leader

Prof. Dr. Mohamed TREBAK
Pennstate University Medical Faculty
2nd International Vice Chairman

Organization Local Chairmans
Assist Prof. Dr. A. Cihangir UĞUZ
Department of Biophysics, School of Medicine
Suleyman Demirel University, Isparta, Turkey

Assist Prof. Dr. Ömer ÇELİK
Department of Biophysics, School of Medicine
Suleyman Demirel University, Isparta, Turkey

Prof. Dr. Fatih GÜLTEKİN
Dean of Faculty of Medicine
Alanya Alaaddin Keykubat University

Prof. Dr. Süleyman KUTLUHAN
Department of Neurology
Suleyman Demirel University School of Medicine

Organization Secretariat
Bilal CİĞ & Mehmet AYKUR & Vahid GHAZIZADEH & Yener YAZĞAN
Department of Biophysics, School of Medicine
Suleyman Demirel University, Isparta, Turkey

Accountants
Ahmi ÖZ & İshak Suat ÖVEY & Ramazan ÇINAR & Ercan SOZBİR (Webmaster)
Department of Biophysics, School of Medicine
Suleyman Demirel University, Isparta, Turkey

Technical Supports
Yener YAZĞAN (Graphic Designer)
Department of Biophysics, School of Medicine
Suleyman Demirel University, Isparta, Turkey

vi 6th World Congress of Oxidative Stress, 24 – 27 May 2016 [ Volume 8, Number 1, 2016 ]
Calcium Signaling and TRP Channels
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Calcium Signaling and TRP Channels

___________ [ Scientific Committee ] ___________

Prof. Dr. Alexey Tepikin
Department of Cellular and Molecular Physiology,
The University of Liverpool, Liverpool, UK

Prof. Dr. Ana B. Rodriguez
Department of Physiology,
University of Extremadura, Badajoz, Spain

Prof. Dr. Cem Ekmekcioğlu
Department of Public Health,
Medical University Vienna, Austria

Prof. Dr. James W. Putney
Calcium Regulation Section,
NIEHS, NC, USA

Prof. Dr. José A. Pariente
Department of Physiology,
University of Extremadura, Badajoz, Spain

Prof. Dr. Mohamed Trebak
The Pennsylvania State University
College of Medicine, USA

Prof. Dr. Özcan Erel
Department of Biochemistry, Faculty of Medicine,
Yıldırım Beyazıt University, Ankara, Turkey

Prof. Dr. Peter McNaughton
Wolfson Centre for Age-Related Research,
King's College London, UK

Prof. Dr. Ramazan Bal
Department of Physiology, Faculty of Medicine,
Gaziantep University, Gaziantep, Turkey

Prof. Dr. Stephan M. Huber
Department of Radiation Oncology,
University of Tübingen, Germany

Prof. Dr. Şefik Dursun
Department of Biophysics, Cerrahpasa Medical Faculty,
Istanbul University, İstanbul, Turkey

Prof. Dr. Valerian E. Kagan
Center for Free Radical and Antioxidant Health,
Department of Environmental and Occupational Health,
University of Pittsburgh, Pittsburgh, PA, USA
6th World Congress of Oxidative Stress, 24 – 27 May 2016 [ Volume 8, Number 1, 2016 ] v i i
Calcium Signaling and TRP Channels
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Calcium Signaling and TRP Channels
_________________ [ CONTENTS ] ________________
Conference
Conference No. 1. Multiple roles of Orai1 calcium channels
James W. Putney, Gary S. Bird, Felicity M. Davis, Pooja Desai, Diane D’Agostin,
Natacha Steinckwich-Besançon ………………………………………………………………...............455
Conference No. 2. Signalling to and from IP3 receptors
Colin W Taylor…….………………………………………………………………………………………...455
Conference No. 3. Optogenetic manipulation of neuronal circuits regulating feeding behavior
Deniz Atasoy…………….…………………………………………………………………..………………456
Conference No. 4. Altered calcium handling in duchenne muscular dystrophy and the role of TRP channels
Heinrich Brinkmeier………………………………………………………………………….………….……456
Conference No. 5. A new intracellular signaling molecule free Zn2+ mediates endoplasmic reticulum
stress in hyperglycemic cardiomyocytes
Belma Turan……...……………………………………………………………………………..……………456
Conference No. 6. Phospholipids reduce the oxidative stress and improve the heart
function after myocardial infarction
Adelina Curaj, Sakine Simseekyilmaz, Mareike Staudt, Andreas Götzenich, Andeea Urs,
Mircea Leabu, Elisa A. Liehn……………………………………………..………………….…...............457
Conference No. 7. Consequences of ATAD3 hemi-deletion in mice: Effects on training and obesity
Denis Rousseau….……………….……………………………………………………………….………..458
Conference No. 8. Non-selective cationic channels and calcium entry mechanisms in the cardiovascular
system
David J. Beech………….……………………………………………………………………………...……459
Conference No. 9. Diversity and specificity of Ca2+ entry pathways in the vascular system
Mohamed Trebak...………………………………………………………………………………….….……459
Conference No.10. Screening of TRPC channel activators identifies novel neurotrophic piperazine
Compounds
Seishiro Sawamura, Masahiko Hatano, Yoshinori Takada, Kyosuke Hino, Tetsuya Kawamura,
Jun Tanikawa, Hiroshi Nakagawa, Hideharu Hase, Akito Nakao, Mitsuru Hirano,
Rachapun Rotrattanadumrong, Shigeki Kiyonaka, Masayuki X. Mori, Motohiro Nishida,
Yaopeng Hu, Ryuji Inoue, Ryu Nagata and Yasuo Mori…………………………………..………..….……459
Conference No.11. Functional Interaction between TRP channels and anoctamin1
Makoto Tominaga……………...……………………………………………………………….................460
Conference No.12. Role of TRPC5 in multidrug resistance of breast cancer
Xin Ma, Jian Jin, Xiaoqiang Yao…………………………………………………………………………..461
Conference No.13. Melatonin and apoptosis induced by intracellular calcium overload
Javier Espino, Ana B. Rodríguez, José A. Pariente…………………………………..………………..461
viii 6th World Congress of Oxidative Stress, 24 – 27 May 2016 [ Volume 8, Number 1, 2016 ]
Calcium Signaling and TRP Channels
Conference No.14. The road to understanding titin phosphorylation and oxidation in heart failure
with preserved ejection fraction
Nazha Hamdani ……………………………………………………………………………..………….……462
Conference No.15. TRPM2 and TRPV1 channels: Potential drug targets for treating epilepsy
Mustafa Nazıroğlu..……………………………………………………………………………..……………463
Conference No.16. Comparison of the oxidative stress-induced ionic currents with the other
identified ionic currents in neurones of the ventral cochlear nucleus
Ramazan Bal…………………………………………………………..…..………………….…...............464
Conference No.17. Proton sensing, TRPC channels and the cerebellum
Maike Glitsch….….……………….……………………………………………………………….………..464
Conference No.18. Exercise improves vascular function in type 2 diabetes: But how?
Ismail Laher …..……….………………………………………………………….…………………...……465
Conference No.19. Oxidative stress in insulin-secreting cells, a putative role in diabetes
Pierre Maechler….……………………………………………………….………………………….….……465
Young Speakers
Y. Speaker No. 1. Increased oxidative stress parameters in children with moderate iodine deficiency
Ozgur Pirgon, Ibrahim Halil Topkaya………………………….………………………………...............467
Y. Speaker No. 2. Investigation of toxic effect of acrylamide on fetal brain development and
protective potentials of N-Acetylcysteine
Mehmet Erman Erdemli, Yusuf Turkoz, Eyup Altınoz..………………….……………………………..467
Y. Speaker No. 3. Alterations in thymic morphology and antioxidant biomarkers in 60-day-old male rats
following exposure to a continuous 900-MHz electromagnetic field during adolescence
Ali Kulaber, Gökçen Kerimoğlu, Ersan Odacı, Şafak Ersöz……….…………………..………………468
Y. Speaker No. 4. Is the hot chili pepper consumption through activation of TRPV1 channel risk for epilepsy?
İrem Karaer, Nur Fidan Çam, Mustafa Nazıroğlu……………….………………………….………….……468
6th World Congress of Oxidative Stress, 24 – 27 May 2016 [ Volume 8, Number 1, 2016 ] i x
Calcium Signaling and TRP Channels