Table Of ContentIntroduction to Clinical Pharmacology
EDITION 9
Constance G. Visovsky, PhD, RN, ACNP,
FAAN
Associate Professor and Director of Diversity
College of Nursing
University of South Florida
Tampa, Florida
Cheryl H. Zambroski, PhD, RN
Associate Professor
College of Nursing
University of South Florida
Tampa, Florida
Shirley Meier Hosler, RN, BSN, MSN
Adjunct Faculty
Santa Fe Community College
Santa Fe, New Mexico
Special Editor
M. Linda Workman, PhD, RN, FAAN
Formerly, Gertrude Perkins Oliva Professor of Oncology
Frances Payne Bolton School of Nursing
Case Western Reserve University
Cleveland, Ohio
2
3
Table of Contents
Cover image
Title Page
Copyright
Reviewers
LPN/LVN Advisory Board
Preface
Organization and Features
Teaching and Learning Package for the Instructor
For the Student
Acknowledgments
About the Authors
To the Student
Reading and Review Tools
Chapter Features
Unit I General Principles
1 Pharmacology and the Nursing Process in LPN Practice
The LPN/VN's Role and the Nursing Process
Get Ready for the NCLEX® Examination!
2 Legal, Regulatory, and Ethical Aspects of Drug Administration
4
Introduction
Regulation of Drug Administration
The Drug Order
Drug Administration Systems
Drug Errors
Protection of Healthcare Workers
Get Ready for the NCLEX® Examination!
3 Principles of Pharmacology
Drug Names
Drug Attachment
Basic Drug Processes
Drug Actions
Drug Therapy and Special Populations
Drug Cards
Get Ready for the NCLEX® Examination!
Unit II Principles of Drug Administration
4 Drug Calculation
Calculating Drug Dosages
Calculations for IV Infusions
General Principles of Drug Administration
Enteral Drugs
Parenteral Drugs
Percutaneous Drugs
Get Ready for the NCLEX® Examination!
Unit III Drug Categories
5 Anti-Infective Drugs
Infection
Antibiotics
Antitubercular Drugs
Antifungal Drugs
Antiparasitic Drugs
5
Get Ready for the NCLEX® Examination!
6 Antivirals and Antiretrovirals
Virus
Antivirals
Retrovirus
Antiretrovirals
Get Ready for the NCLEX® Examination!
7 Drugs for Allergy and Respiratory Problems
Allergy
Drug Therapy for Allergy
Asthma and Chronic Obstructive Pulmonary Disease
Drug Therapy for Asthma and Chronic Obstructive Pulmonary Disease
Mucolytics and Antitussives
Get Ready for the NCLEX® Examination!
8 Drugs Affecting the Renal/Urinary and Cardiovascular Systems
Drugs That Affect the Renal/Urinary System
Drugs That Affect the Cardiovascular System
Get Ready for the NCLEX® Examination!
9 Drug Therapy for Central Nervous System Problems
Drugs for Epilepsy
Get Ready for the NCLEX® Examination!
10 Drug Therapy for Mental Health
Drug Therapy and Mental Illness
Drugs for Sleep and Anxiety
Antipsychotics
Antidepressants and Mood Stabilizers
Get Ready for the NCLEX® Examination!
11 Drugs for Pain Management
Pain
6
Analgesic Drugs for Pain Management
Miscellaneous Drugs for Pain Management
Get Ready for the NCLEX® Examination!
12 Anti-Inflammatory, Antiarthritis, and Antigout Drugs
Inflammation Causes and Action
Inflammation Management
Gout
Get Ready for the NCLEX® Examination!
13 Drugs for Gastrointestinal Problems
The Digestive System
Antiemetic Drugs
Drugs for Peptic Ulcer Disease and Gastroesophageal Reflux Disease
Drugs for Constipation and Diarrhea
Get Ready for the NCLEX® Examination!
14 Drugs Affecting the Hematologic System
Blood Clotting
Anticoagulants
Fibrinolytic Drugs
Erythropoiesis-Stimulating Agents
Get Ready for the NCLEX® Examination!
15 Drugs for Immunization and Immunomodulation
Overview of Immunity
Vaccination
Immunomodulating Therapy
Get Ready for the NCLEX® Examination!
16 Hormones and Drugs for Osteoporosis
Overview of the Endocrine System
Drugs for Thyroid Problems
Drugs for Adrenal Gland Problems
Female Sex Hormones
7
Male Sex Hormones
Drugs for Osteoporosis
Get Ready for the NCLEX® Examination!
17 Drug Therapy for Diabetes
Drug Therapy for Diabetes Mellitus
Get Ready for the NCLEX® Examination!
18 Drugs for Ear and Eye Problems
Ear Problems
Eye Problems
Get Ready for the NCLEX® Examination!
19 Over-the-Counter Drugs, Herbal and Alternative Drugs, and Vitamins and
Minerals
Overview
Over-the-Counter Drugs
Herbal Products and Complementary and Alternative Medicine
Vitamins
Minerals
Get Ready for the NCLEX® Examination!
Bibliography
Glossary
A
B
C
D
E
F
G
H
I
L
8
M
N
O
P
R
S
T
U
V
W
Z
Index
9
Copyright
3251 Riverport Lane
St. Louis, Missouri 63043
INTRODUCTION TO CLINICAL PHARMACOLOGY, NINTH EDITION
ISBN: 978-0-323-52911-2
Copyright © 2019 Elsevier Inc. All rights reserved.
Previous editions copyrighted 2016, 2013, 2010, 2006, 2000, 1995, 1991.
No part of this publication may be reproduced or transmitted in any form or by any
means, electronic or mechanical, including photocopying, recording, or any
information storage and retrieval system, without permission in writing from the
publisher. Details on how to seek permission, further information about the
Publisher's permissions policies and our arrangements with organizations such as
the Copyright Clearance Center and the Copyright Licensing Agency, can be found
at our website: www.elsevier.com/permissions.
This book and the individual contributions contained in it are protected under
copyright by the Publisher (other than as may be noted herein).
Notices
Practitioners and researchers must always rely on their own experience and
knowledge in evaluating and using any information, methods, compounds or
experiments described herein. Because of rapid advances in the medical sciences, in
particular, independent verification of diagnoses and drug dosages should be made.
To the fullest extent of the law, no responsibility is assumed by Elsevier, authors,
editors or contributors for any injury and/or damage to persons or property as a
matter of products liability, negligence or otherwise, or from any use or operation of
any methods, products, instructions, or ideas contained in the material herein.
Library of Congress Cataloging-in-Publication Data
Names: Visovsky, Constance G., editor. | Preceded by (work): Edmunds, Marilyn W.
Introduction to clinical pharmacology.
Title: Introduction to clinical pharmacology / special editor, M. Linda Workman.
Description: 9th edition. | St. Louis, Missouri : Elsevier Inc., [2019] | Preceded by
Introduction to clinical pharmacology / Marilyn Winterton Edmunds. 2016. |
Includes bibliographical references and index.
10