Table Of Contentw
EBOOKS Hydroxyapatite O
S BIOMATERIALS ENGINEERING
H
FOR THE Synthesis and Applications ID
A COLLECTION
ENGINEERING
Yoshiki Oshida
LIBRARY
Evidence-based literature reviews can provide foundation skills
Create your own in research-oriented bibliographic inquiry, with an emphasis on
Customized Content such review and synthesis of applicable literature. Information
Bundle—the more is gathered by surveying a broad array of multidisciplinary
research publications written by scholars and researchers.
books you buy,
Hydroxyapatite
This book is based on a review of about 2,000 carefully
the greater your
selected articles about hydroxyapatite (HA) materials from
discount!
about 150 peer-review journals in both engineering and medical
areas and presents itself as a typical example of evidence-
THE CONTENT Synthesis and Applications
based learning (EBL). HA is very unique material which has
• Manufacturing
been employed equally in both engineering and medical and
Engineering
dental fields. In addition, the name “apatite” comes from the
• Mechanical
Greek word απατw, which means to deceive. What is actually
& Chemical
happening inside the apatite crystal structure is based on the
Engineering
unique characteristics of ion exchangeability. Because of this,
H
• Materials Science
versatility of HA has been recognized in wide ranges, including y
& Engineering d
bone-grafting substitutes, various ways to fabricate HAs, HA-
r
• Civil & o
based coating materials, HA-based biocomposites, scaffold x
Environmental y
materials, and drug-delivery systems. This book covers all a
Engineering p
these interesting areas involved in HA materials science and
a
• Advanced Energy technology. ti
t
Technologies e
Yoshiki Oshida is a professor emeritus at Indiana University
School of Dentistry, an adjunct professor at University of
THE TERMS
California San Francisco School of Dentistry, a visiting professor
• Perpetual access for
at Taipei Medical University, and a foreign advisor at Waseda
a one time fee
University Research Promotion Division. He received his MS in
• No subscriptions or
materials science from Syracuse University, Syracuse NY and
access fees
his PhD in materials science and engineering from Waseda
• Unlimited
University, Tokyo Japan. In addition to numerous conference
concurrent usage
presentations and invited lectures (Canada, Korea, Taiwan,
• Downloadable PDFs
Turkey, Japan, etc.), he also holds 10 U.S. patents and is the
• Free MARC records
author of over 100 papers and contributed book chapters. He
is the author of Bioscience and Bioengineering of Titanium
For further information,
Materials (2011), and Surface Engineering and Technology for Yoshiki Oshida
a free trial, or to order,
Biomedical Implants (2014).
contact:
[email protected]
IISSBBNN :9 7987-81--16-06605605-06-7537-48-8
HYDROXYAPATITE
HYDROXYAPATITE
SYNTHESIS AND
APPLICATIONS
YOSHIKI OSHIDA
MOMENTUM PRESS, LLC, NEW YORK
Hydroxyapatite: Synthesis and Applications
Copyright © Momentum Press®, LLC, 2015.
All rights reserved. No part of this publication may be reproduced, stored
in a retrieval system, or transmitted in any form or by any means—
electronic, mechanical, photocopy, recording, or any other—except for
brief quotations, not to exceed 400 words, without the prior permission
of the publisher.
First published by Momentum Press®, LLC
222 East 46th Street, New York, NY 10017
www.momentumpress.net
ISBN-13: 978-1-60650-673-8 (print)
ISBN-13: 978-1-60650-674-5 (e-book)
Momentum Press Biomaterials Engineering Collection
DOI: 10.5643/9781606506745
Cover and interior design by Exeter Premedia Services Private Ltd.,
Chennai, India
10 9 8 7 6 5 4 3 2 1
Printed in the United States of America
To my wife, for putting up with me, and to my parents and family
members, for their love, support, and encouragement
A
bstrAct
This book is based on a review of about 2,000 carefully selected articles
about hydroxyapatite (HA) materials from about 150 peer-review journals
in both engineering and medical areas and presents itself as a typical exam-
ple of evidence-based learning (EBL). Evidence-based literature reviews
can provide foundation skills in research-oriented bibliographic inquiry,
with an emphasis on such review and synthesis of applicable literature.
Information is gathered by surveying a broad array of multidisciplinary
research publications written by scholars and researchers. HA is a very
unique material which has been employed equally in both engineering and
medical and dental fields. In addition, the name “apatite” comes from the
Greek word απατω, which means to deceive. What is actually happening
inside the apatite crystal structure is based on the unique characteristics
of ion exchangeability. Because of this, versatility of HA has been recog-
nized in wide ranges, including bone-grafting substitutes, various ways
to fabricate HAs, HA-based coating materials, HA-based biocomposites,
scaffold materials, and drug-delivery systems. This book covers all these
interesting areas involved in HA materials science and technology.
KEY WORDS
animal tests, biomimetic materials, biowaste-origin HA, biphasic bio-
composites, bone-graft substitute materials, clinical reports, crystallinity,
drug-delivery systems, elemental substitutions, hydroxyapatite coating
materials, hydroxyapatite-based biocomposites, scaffolds materials and
structures, synthesis
vii
c
ontents
List of figures xiii
List of tabLes xv
acknowLedgments xvii
Preface xix
1 introduction 1
References 5
2 structure and ProPerties 7
2.1 Introduction 7
2.2 High-temperature and Low-temperature HAs 8
2.3 Dissolution and Solubility 10
2.4 Compositional Alteration of HA 11
2.5 Crystallinity and Its Effects 12
2.6 Ca–P Family Members 17
2.7 Comparison between HA and TCP 19
2.8 HA/TCP Biphasic Biocomposites 22
References 25
3 PreParation of HydroxyaPatite 33
3.1 Introduction 33
3.2 Sources for Calcium in HA 33
3.3 HA Synthesis Technologies 34
References 44
ix
