Download Histopath Notes in Fixation PDF Free - Full Version
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About Histopath Notes in Fixation
1. Fixation is the process of killing, penetrating, and hardening tissues to prevent further degradation and preserve tissues for examination. The primary goal is to stabilize proteins so tissues resist changes. 2. Key factors in fixation include temperature, thickness/size of tissues, pH, osmolality, concentration of fixative, duration of exposure, and volume of fixative used. Overfixation can damage tissues while underfixation allows degradation. 3. Common fixatives work by different mechanisms, either stabilizing tissue proteins as formaldehyde does or reacting with cell components like osmium tetroxide. The right fixative must be chosen based on the tissue and intended downstream applications.
Detailed Information
| Author: | ['CIRILO MABBORANG'] |
|---|---|
| Publication Year: | 2023 |
| Pages: | 6 |
| Language: | English |
| Format: | |
| Price: | FREE |
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