Handbook of Renal and Pancreatic Transplantation

489 Pages·2012·5.79 MB·English

Handbook of Renal and
Pancreatic Transplantation
Companion website
This book is accompanied by a companion website:
www.wiley.com/go/macphee/transplantation
The website includes:
• 60 full - colour fi gures to accompany Chapters 7 and 10
• Video clips of live donor nephrectomy to accompany Chapter 7
Handbook of Renal
and Pancreatic
Transplantation
EDITORS
Iain A. M. MacPhee
Division of Clinical Sciences: Renal Medicine, St. George’s, University of London;
Department of Renal Medicine and Transplantation, St. George’s Hospital, Blackshaw
Road, London, UK
Jirˇí Froneˇk
Transplant Surgery Department, Institute for Clinical and Experimental Medicine,
Prague, Czech Republic;
2nd Medical Faculty, Charles University, Prague, Czech Republic
A John Wiley & Sons, Ltd., Publication
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Library of Congress Cataloging-in-Publication Data
Handbook of renal and pancreatic transplantation / editors, Iain A. M. MacPhee, Jirˇi Froneˇk.
p. ; cm.
Includes bibliographical references and index.
ISBN 978-0-470-65491-0
I. MacPhee, Iain A. M. II. Froneˇk, Jirˇi, 1970–
[DNLM: 1. Kidney Transplantation. 2. Pancreas Transplantation. WJ 368]
617.4'610592–dc23
2011049799
A catalogue record for this book is available from the British Library.
Wiley also publishes its books in a variety of electronic formats. Some content that appears in
print may not be available in electronic books.
Set in 9.25/11.5 pt Minion by Toppan Best-set Premedia Limited
1 2012
For: Paula, Laura, Lucy, Madeleine, Eli š ka, Krist ý na and M á ja.
Contents
List of Contributors, ix
Preface, xiii
Abbreviations List, xv
1 History of transplantation, 1
Jiˇrí Fronˇek and Iain MacPhee
2 Assessment of the potential renal transplant recipient, 9
Patrick B. Mark and Alan G. Jardine
3 Pre-transplant assessment and medical evaluation
of potential live kidney donors, 33
Jonas Wadström
4 Histocompatibility and immunogenetics, 55
Susan V. Fuggle and Craig J. Taylor
5 Donor management: care of the heartbeating brain-dead
multi - organ donor, 77
Paul G. Murphy
6 Deceased donor retrieval, 91
Albert M. Wolthuis, Diethard Monbaliu, Willy Coosemans
and Jacques Pirenne
7 Live donor nephrectomy, 109
Jirˇí Fronˇek and Nicos Kessaris
8 Organisation of transplant services, organ sharing and organ
allocation: A perspective from the UK and Eurotransplant, 141
James Neuberger and Axel Rahmel
9 Deceased donor kidney transplantation, 159
Luisa Berardinelli
10 Living donor kidney transplantation, 173
Jiˇrí Fronˇek and Nicos Kessaris
11 Pancreas transplantation, 191
Guido Woeste and Wolf O. Bechstein
12 Pancreatic islet transplantation, 203
František Saudek
vii
viii Contents
13 Anaesthesia for renal transplantation, 219
Nicoletta Fossati
14 Anaesthesia for pancreatic transplantation, 227
Kai Zacharowski and Hans-Joachim Wilke
15 Anaesthesia for live donor nephrectomy, 235
Rehana Iqbal and Karthik Somasundaram
16 Immunosuppression, 243
Iain A.M. MacPhee and Teun van Gelder
17 Antibody-incompatible kidney transplantation, 271
Nicos Kessaris and Nizam Mamode
18 Renal transplantation in children, 287
Luisa Berardinelli and Luciana Ghio
19 Post-transplant diagnostic imaging, 297
Lakshmi Ratnam and Uday Patel
20 Transplant histopathology, 317
Eva Honsová
21 Infection, 335
Rachel Hilton and Martin W. Drage
22 Management during the fi rst three months after renal
transplantation, 381
Iain A.M. MacPhee, Joyce Popoola and Daniel Jones
23 Management of long-term complications, 403
Paul N. Harden, Richard Haynes, Iain A.M. MacPhee and Jirˇí Fronˇek
24 Living donor follow-up, 437
Robert Elias and Jirˇí Fronˇek
25 Ethics of transplantation, 447
Robert Elias and Rehana Iqbal
Index, 461
Companion website
This book is accompanied by a companion website:
www.wiley.com/go/macphee/transplantation
List of Contributors
Wolf O. Bechstein
Department of General and Visceral Surgery, Johan Wolfgang Goethe
University Frankfurt, Germany.
Luisa Berardinelli
General Surgery and Kidney Transplantation Unit, Policlinico University
Hospital IRCCS, Milan, Italy.
Willy Coosemans
Department of Thoracic Surgery, University Hospitals Leuven, Belgium.
Martin W. Drage
Renal, Urology and Transplantation Directorate, Guy ’ s Hospital, London,
UK.
Robert Elias
Renal Unit, King ’ s College Hospital, NHS Foundation Trust, London, UK.
Nicoletta Fossati
Department of Anaesthesia, St. George ’ s Healthcare NHS Trust, London,
UK.
Ji rˇ í Fron eˇ k
Transplant Surgery Department, Institute for Clinical and Experimental
Medicine, Prague, Czech Republic.
2nd Medical Faculty, Charles University, Prague, Czech Republic.
Susan V. Fuggle
Transplant Immunology and Immunogenetics, Oxford Transplant Centre,
Churchill Hospital, Oxford, UK.
Luciana Ghio
Department of Pediatrics, Policlinico University Hospital IRCCS, Milan,
Italy.
Teun van Gelder
Nephrology and Clinical Pharmacology, Erasmus Medical Centre,
Rotterdam, Netherlands.
Paul N. Harden
Renal Medicine and Transplantation, St. George ’ s Healthcare NHS Trust,
London, UK.
Richard Haynes
Renal Medicine and Transplantation, St. George ’ s Healthcare NHS Trust,
London, UK.
ix
x List of Contributors
Rachel Hilton
Renal, Urology and Transplantation Directorate, Guy ’ s Hospital,
London, UK.
Eva Honsov á
Clinical and Transplant Pathology Department, Institute for Clinical and
Experimental Medicine, Prague, Czech Republic.
Rehana Iqbal
Anaesthesia Department, St. George ’ s Healthcare NHS Trust, London, UK.
Alan G. Jardine
BHF Glasgow Cardiovascular Research Centre, University of Glasgow,
Glasgow, UK.
Daniel Jones
Renal Medicine and Transplantation, St. George ’ s Healthcare NHS Trust,
London, UK.
Nicos Kessaris
Department of Renal Medicine and Transplantation, St. George ’ s
Healthcare NHS Trust, Blackshaw Road, London, UK.
Iain A.M. MacPhee
Division of Clinical Sciences: Renal Medicine, St. George ’ s Healthcare
NHS Trust, University of London, London, UK.
Department of Renal Medicine and Transplantation, St. George ’ s
Healthcare NHS Trust, Blackshaw Road, London, UK.
Nizam Mamode
Renal, Urology and Transplantation Directorate, Guy ’ s Hospital, London,
UK.
Patrick B. Mark
BHF Glasgow Cardiovascular Research Centre, University of Glasgow,
Glasgow, UK.
Diethard Monbaliu
Department of Abdominal Transplant Surgery, University Hospitals
Leuven, Belgium.
Paul G. Murphy
National Clinical Lead for Organ Donation, NHS Blood and Transplant
and Department of Neuroanaesthesia and Critical Care, Leeds Genereal
Infi rmary, Leeds, UK.
James Neuberger
Liver Department, University Hospitals Birmingham. NHS Foundation
Trust, Birmingham, UK.
Uday Patel
Radiology Department, St. George ’ s Healthcare NHS Trust, London, UK.
J acques Pirenne
Department of Abdominal Transplant Surgery, University Hospitals
Leuven, Belgium.
List of Contributors xi
Joyce Popoola
Renal Medicine and Transplantation, St. George ’ s Healthcare NHS Trust,
London, UK.
Axel Rahmel
Eurotransplant International Foundation, Leiden, Netherlands.
Lakshmi Ratnam
Radiology, St. George ’ s Healthcare NHS Trust, London, UK.
Franti š ek Saudek
Diabetes Center, Institute for Clinical and Experimental Medicine,
Prague, Czech Republic.
Karthik Somasundaram
Anaesthesia Department, St George ’ s Healthcare NHS Trust London, UK.
Craig J. Taylor
Transplant Immunology and Immunogenetics, Oxford Transplant Centre,
Churchill Hospital, Oxford, UK.
Jonas Wadstr ö m
Departments of Transplantation Surgery and Transfusion Medicine,
Karolinska University Hospital, Huddinge, Stockholm; Department of
Transplantation Surgery, Karolinska University Hospital, Sweden.
Hans - Joachim Wilke
Clinic of Anesthesiology, Intensive Care Medicine and Pain Therapy
University Hospital Frankfurt am Main, Germany.
Guido Woeste
Department of General and Visceral Surgery, Johan Wolfgang Goethe
University Frankfurt, Germany.
Albert M. Wolthuis
Department of Abdominal Surgery, University Hospitals Leuven,
Belgium.
Kai Zacharowski
Clinic of Anesthesiology, Intensive Care Medicine and Pain Therapy
University Hospital Frankfurt am Main, Germany.