Table Of ContentHandbook of Dermatology
Handbook of
Dermatology
A Practical Manual
SeconD eDition
Margaret W. Mann, MD
Associate Professor and Director of Aesthetic Dermatology
University Hospitals, Case Western School of Medicine
Cleveland, OH, USA
Co-Founder
Innova Dermatology
Hendersonville, TN, USA
Daniel L. Popkin, MD PhD
Assistant Chief of Dermatology, Louis Stokes VA Medical Center
Assistant Professor of Dermatology
University Hospitals, Case Western School of Medicine
Cleveland, OH, USA
Co-Founder
Innova Dermatology
Hendersonville, TN, USA
This edition first published 2020
© 2020 by John Wiley & Sons Ltd
Edition History [1e, 2009]
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Library of Congress Cataloging‐in‐Publication Data
Names: Mann, Margaret W., author. | Popkin, Daniel L., author.
Title: Handbook of dermatology : a practical manual / Margaret W. Mann, Daniel L. Popkin.
Description: Second edition. | Hoboken, NJ : Wiley Blackwell, 2020. | Preceded by Handbook of dermatology /
Margaret W. Mann ... [et al.]. 2009. | Includes bibliographical references and index. |
Identifiers: LCCN 2019003278 (print) | LCCN 2019004180 (ebook) | ISBN 9781118408537 (Adobe PDF) |
ISBN 9781118408520 (ePub) | ISBN 9781118408544 (pbk.)
Subjects: | MESH: Skin Diseases–diagnosis | Skin Diseases–therapy | Dermatologic Agents–therapeutic use |
Handbook
Classification: LCC RL74 (ebook) | LCC RL74 (print) | NLM WR 39 | DDC 616.5–dc23
LC record available at https://lccn.loc.gov/2019003278
Cover Design: Wiley
Cover Images: © STEVE GSCHMEISSNER/SCIENCE PHOTO LIBRARY/Getty Images
Set in 7.5/9.5 Frutiger by SPi Global, Pondicherry, India
10 9 8 7 6 5 4 3 2 1
Dedication
This second edition is dedicated to our son Samuel. Without you, completing
this second edition would have been so much faster and less fun.
Contents
Preface, xv
Acknowledgments, xvii
Part 1 General Dermatology, 1
Common Work-uPs, signs, And mAnAgement, 3
dermatologic differential Algorithm, 3
direct immunofluorescence (dif), 3
False positive/negative diFs, 3
Workup Quick reference orders, 4
Acne, 6
Alopecia Workup, 7
telogen effluvium, 10
Androgenic alopecia, 10
Alopecia areata, 11
other alopecia treatments, 12
Aphthosis Workup and treatment, 13
dermatologic signs, 15
Folliculitis, 21
melasma, 22
immunology And immunologiC diseAse, 24
lupus erythematosus, 24
Autoantibody, 26
sensitivities and specificities, 26
in connective tissue diseases, 28
Anti‐nuclear antibodies, 29
AnCA (Anti‐neutrophil cytoplasmic antibodies), 30
treatment of AnCA‐associated vasculitis, 30
Vasculitis, 31
small vessel vasculitis, 31
medium vessel vasculitis, 33
large vessel vasculitis, 34
Cryoglobulinemia, 34
Bullous disorders, 36
intracorneal/subcorneal, 36
intraepidermal, 36
suprabasilar, 37
subepidermal with little inflammation, 37
epidermolysis bullosa, 39
major bullous diseases – clinicopathologic findings, 42
vii
Complement, 46
Angioedema and complement levels, 46
Complement deficiencies, 47
gVHd, 47
HlA associations, 48
th profiles, 50
sPeCiAl sites: glAnds, nAil, Bone, muCosA, 51
glands, 51
nail terminology, 53
disorders or drugs associated with nail, bone, or ocular findings, 57
genital ulcers, 67
inFeCtion And inFestAtions, 68
Fungal disease / mycoses, 68
laboratory tests, 68
superficial mycoses, 68
Cutaneous mycoses, 69
subcutaneous mycoses, 71
systemic mycoses, 73
opportunistic mycoses, 75
Viruses and diseases, 78
Human papilloma virus, 79
other viral diseases, 80
infections/Bugs, 83
Vector‐borne diseases, 83
Creatures in dermatology, 88
ContACt And PlAnt dermAtitis, 93
Patch testing, 93
Common contact allergens, 95
Allergic vs. irritant contact dermatitis, 104
Allergens – location specific, 105
Features suggestive of specific irritant/toxin, 106
Plants and dermatoses, 106
tumors snd inFiltrAtes, 109
Cutaneous t Cell lyphoma, 109
Cutaneous B‐cell lymphoma, 113
leukemia cutis, 113
monoclonal gammopathies in dermatology, 114
tumors and gene associations, 115
For melanoma, BCC, and sCC, see skin Cancer, 221
viii
