Table Of Contentu
Journal of the British Society of Gastroenterology which
is a registered charity
VOLUME 38 - 1996
Editor: Michael J G Farthing Special Sections Editor: Ian Forgacs
Associate Editors: Michael J P Arthur, John Calam, Roger Chapman, Michaei A Kamm,
Thomas T MacDonald
Technical Editor: Jackie Foulds Editorial Assistants: Michelle Dimler
Julia Neary
EDITORIAL BOARD
D Adams (UK) S Hubscher (UK) D S Rampton (UK)
D Alderson (UK) P Jansen (The Netherlands) J Rask-Madsen (Denmark)
C Arvanitakis (Greece) J] Jass (New Zealand) P Rutgeerts (Belgium)
G Bianchi Porro (Italy) G Krejs (Austria) G Sandle (UK)
I Booth (UK) S K Lam (Hong Kong) C Scarpignato (Italy)
M Buchler (Switzerland) N Lemoine (UK) E Schurmpf (Norway)
E Butruk (Poland) M M Levine (USA) P Shorvon (UK)
J Dent (Australia) O Lundgren (Sweden) D Thompson (UK)
G Dockray (UK) P Malfertheiner (Germany) G Tytgat (The Netherlands)
J Galmiche (France) J Neoptolemos (UK) B J R Whittle (UK)
J Heathcote (Canada) D Rachmilewitz (Israel) T Wright (UK)
R G Newcombe Editor
(Statistical adviser) British Medical Fournal
VOLUME 38 - CONTENTS
No 1 JANUARY 1996 Page Leading article
l Labelled leucocyte scintigraphy in inflammatory bowel disease: clinical applications M H Giaffer
Gastroduodenal disease
6 Omeprazole promotes proximal duodenal mucosal bicarbonate secretion in humans A Mertz-Nielsen, ¥ Hillingse,
K Bukhave, ¥ Rask-Madsen
11 Comparison of effects of calcium carbasalate and aspirin on gastroduodenal mucosal damage in human
volunteers FE Murray, N Hudson, 7 C Atherton, A T Cole, F Scheck, C ¥ Hawkey
15 Helicobacter pylori may induce bile reflux: link between H pylori and bile induced injury to gastric epithelium
S D Ladas, } Katsogridakis, H Malamou, H Giannopoulou, M Kesse-Elia, S A Raptis
19 Helicobacter pylori increases proliferation of gastric epithelial cells X G Fan, D Kelleher, X ¥#F an, H X Xia,
PW WN Keeling
23 Relation between gastric emptying rate and rate of intraluminal lipolysis BD Maes, Y F Ghoos, B F Geypens,
M I Hele, P F Rutgeerts
Small intestine
28 Oral administration of protease inhibits enterotoxigenic Escherichia coli receptor activity in piglet small intestine
T L Mynott, R K ¥ Luke, D S Chandler
33 Positive somatostatin receptor scintigraphy correlates with the presence of somatostatin receptor subtype 2
M Fohn, W Meyerhof, D Richter, B Waser, J-C Schaer, H Scheriibl, } Boese-Landgraf, P Neuhaus, C Ziske,
K Maélling, E-O Riecken, ¥ C Reubi, B Wiedenmann
40 Osmotic diarrhoea and skeletal muscle protein synthesis in vivo H Ansell, ¥ S Marway, A B Bonner,
FR Salisbury, D C A Candy, V R Preedy
47 Polyamine metabolism of enterocyte-like Caco-2 cells after exposure of Phaseolus vulgaris lectin
JF F F G Koninkx, D S Brown, W Kok, H G C F Hendriks, A Pusztai, S Bardocz
53 In vitro contractile effects of short chain fatty acids in the rat terminal ileum C Cherbut, A-C Aubé, H M Blottiére,
P Pacaud, C Scarpignato, 7-P Galmiche
59 Calcium in milk and fermentation by yoghurt bacteria increase the resistance of rats to salmonella infection
I Bovee-Oudenhoven, D Termont, R Dekker, R Van der Meer
Gastrointestinal cancer
66 Elongation factor ly mRNA expression in oesophageal carcinoma K Mimon, M Mori, H Inoue, H Veo,
K Mafune, T Akiyoshi, K Sugimachi
71 Mucosal ablation using photodynamic therapy for the treatment of dysplasia: an experimental study in the normal
ratstomach C S Loh, A ¥ MacRobert, G Buonaccorsi, N Krasner, S G Bown
79 Cyclooxygenase-1 and cyclooxygenase-2 gene expression in human colorectal adenocarcinomas and in
azoxymethane induced colonic tumours in rats C Gustafson-Svdrd, I Lilja, O Hallbéék, R Sjédahl
85 Lymphocyte subset infiltration patterns and HLA antigen status in colorectal carcinomas and adenomas
P A Fackson, M A Green, C G Marks, R 7 B King, R Hubbard, M G Cook
Inflammatory bowel disease
90 Interleukin 8: cells of origin in inflammatory bowel disease M C Grimm, S K O Elsbury, P Pavli, W F Doe
99 Microalbuminuria correlates with intestinal histopathological grading in patients with inflammatory bowel disease
M Mahmud, G S A McDonald, D Kelleher, D G Weir
104 ~—sCE ffect of c-kit ligand, stem cell factor, on mediator release by human intestinal mast celis isolated from patients
with inflammatory bowel disease and controls SC Bischoff, S Schwengberg, K Wordelmann, A Weimann, R Raab,
M P Manns
115. 5-Aminosalicylic acid inhibits the impaired epithelial barrier function induced by gamma interferon
M C Di Paolo, M N Merrett, B Crotty, D P Fewell
Gastrointestinal blood loss
120 Use of whole gut perfusion to investigate gastrointestinal blood loss in patients with iron deficiency anaemia
A Ferguson, W G Brydon, H Brian, A Williams, M ¥ Mackie
Liver
125. Chemoembolisation with lipiodol and doxorubicin: applicability in British patients with hepatocellular carcinoma
S D Ryder, P M Rizzi, E Metivier, ¥}K aran, Roger Williams
129 Assessment of variceal pressure by continuous non-invasive endoscopic registration: a placebo controlled
evaluation of the effect of terlipressin and octreotide F Nevens, W Van Steenbergen, S H Yap, 7 Fevery
135 Distribution of lactoferrin and 60/65 kDa heat shock protein in normal and inflamed human intestine and liver
E Peen, S Enestrém, T Skogh
Laparoscopic cholecystectomy
141 Treatment of bile duct lesions after laparoscopic cholecystectomy ~%GH M Bergman, G R van den Brink,
E A F Rauws, L de Wit, H Obertop, K Huibregtse, G N F Tytgat, D-¥ Gouma
Case reports
148 Ulcerative colitis complicated by renal cell carcinoma: a series of three patients 7% Satsangi, ¥M arshall, D Roskell,
D Jewell
151 ‘Fragile’ liver and massive hepatic haemorrhage due to hereditary amyloidosis R F Harnson, P N Hawkins,
W R Roche, R F T MacMahon, S G Hubscher, ¥ A C Buckels
153 Letters tothe editor Bookreviews Notes
158 Referees
No 2 FEBRUARY 1996 Leading article
161 Gene therapy in gastroenterology H S Pandha, N R Lemoine
Oesophagus
166 Effects of mediastinal irradiation on oesophageal function E Yeoh, R H Holloway, A Russo, M Tippett,
H Bermingham, B Chatterton, M Horowitz
Stomach
171 Ascorbic acid and total vitamin C concentrations in plasma, gastric juice, and gastrointestinal mucosa: effects of
gastritis and oral supplementation A } Waring, I M Drake, C F Schorah, K L M White, D A F Lynch,
A T R Axon, M F Dixon
Contents
Gastric epithelial cell kinetics in the progression from normal mucosa to gastric carcinoma R F Cahill,
C Kilgallen, S Beattie, H Hamilton, C O’Morain
Isolated guinea pig gastric chief cells express tumour necrosis factor receptors coupled with the sphingomyelin
pathway S Fiorucci, L Santucci, G Migliorati, C Riccardi, A Amorost, A Mancini, R Roberti, A Morelli
Small intestine
T cell receptor VB expression in human intestine: regional variation in postnatal intestine and biased usage in
fetal gut R Thomas, G Schiirmann, P Lionetti, S L F Pender, T T MacDonald
Cholesterol crystal embolisation to the alimentary tract W Moolenaar, C B H W Lamers
Mechanisms underlying neutrophil adhesion to apical epithelial membranes ~ Meenan, M Mevissen,
H Monajemi, S A Radema, H R Soule, M Moyle, G N 7 Tytgat, S 7 H van Deventer
Faecal a, antitrypsin as a marker of gastrointestinal disease in HIV antibody positive individuals D Sharpstone,
A Rowbottom, M Nelson, B Gazzard
Inflammatory bowel disease
Absence of measles viral genomic sequence in intestinal tissues from Crohn’s disease by nested polymerase chain
reaction Y Haga, O Funakoshi, K Kuroe, K Kanazawa, H Nakajima, H Saito, Y Murata, A Munakata, Y Yoshida
Increased interleukin 8 expression in the colon mucosa of patients with inflammatory bowel disease R Daig,
T Andus, E Aschenbrenner, W Falk, ¥ Schélmerich, V Gross
Increased degradation of type I collagen in patients with inflammatory bowel disease ¥ Si/vennoinen, L Risteli,
T Karttunen, F Risteli
A randomised trial comparing mesalazine and prednisolone foam enemas in patients with acute distal ulcerative
colitis FJ Lee, D P Fewell, V Mam, M RB Keighley, R D Kingston, C O Record, R H Grace, S Daniels,
F Patterson, K Smith
Pouchitis after ileal pouch-anal anastomosis for ulcerative colitis occurs with increased frequency in patients with
associated primary sclerosing cholangitis C Penna, R Dozois, W Tremaine, W Sandborn, N LaRusso, C Schieck,
D Ilstrup
Large intestine
Direct secretory effect of interleukin-1 via type I receptors in human colonic mucous epithelial cells
(HT29-C1.16E) A Jarry, G Vallette, J7-E Branka, C Laboisse
Characteristics of two basolateral potassium channel populations in human colonic crypts RB Lomax,
G Warhurst, G I Sandle
Differential expression of complement proteins and regulatory decay accelerating factor in relation to
differentiation of cultured human colon adenocarcinoma cell lines M-F Bernet-Camard, M-H Coconnier,
S Hudault, A L Servin
Changes of the mucosal n3 and né6 fatty acid status occur early in the colorectal adenoma-carcinoma sequence
F Fernandez-Banares, M Esteve, E Navarro, E Cabré, ¥ Boix, A Abad-Lacruz, ¥ Klaassen, R Planas, P Humbert,
C Pastor, M A Gassull
Liver
Influence of dietary nucleotides on liver structural recovery and hepatocyte binuclearity in cirrhosis induced by
thioacetamide M I Torres-Loépez, I Fernandez, L Fontana, A Gil, A Rios
p53 Protein overexpression in cholangiocarcinoma arising in primary sclerosing cholangitis PM Rizzi,
S D Ryder, B Portmann, 7 K Ramage, N V Naoumov, Roger Williams
Hepatitis C virus: epidemiology and genotypes in the north east of England ¥~ P Watson, A M Brind,
C E Chapman, C L Bates, F K Gould, S ¥ Johnson, A D Burt, ¥ Ferguson, P Simmonds, M F Bassendine
Gall stones
Prospective evaluation of endoscopic ultrasonography and microscopic examination of duodenal bile in the
diagnosis of cholecystolithiasis in 45 patients with normal conventional ultrasonography P Dahan,
C Andant, P Lévy, P Amouyal, G Amouyal, M Dumont, S Erlinger, A Sauvanet, ¥ Belghiti, M Zins, V Vilgrain,
P Bernades
Increased cholecystectomy rate after the introduction of laparoscopic cholecystectomy in Scotland
Chi-Ming Lam, F E Murray, A Cuschieri
Pancreas
Effects of prolonged ethanol intake and malnutrition on rat pancreas ¥M Lopez, ¥ A Bombi, R Valderrama,
A Giménez, A Parés, ¥ Caballeria, S Imperial, S Navarro
Is intervention necessary after a first episode of acute idiopathic pancreatitis? A B Ballinger, E Barnes,
E M Alstead, P D Fairclough
Case reports
Langerhan’s cell histiocytosis complicating small bowel Crohn’s disease C Lee-Elliott, ¥A lexander, A Gould,
R Talbot, ¥ A Snook
A case of Churg-Strauss syndrome: tissue diagnosis established by sigmoidoscopic rectal biopsy E F Leen,
P F Rees, ¥D Sanderson, M L Wilkinson, M I Filipe
Letters to the editor Bookreview Correction
No 3 MARCH 1996 Leading articles
Why is epidermal growth factor present in the gut lumen? R 7 Playford, N A Wright
Age related changes in gut physiology and nutritional status LL B Lovat
Upper gastrointestinal tract
Effects of cisapride on gastric emptying of oil and aqueous meal components, hunger, and fullness K L Jones,
M Horowitz, B I Carney, W M Sun, B E Chatterton
Risk assessment after acute upper gastrointestinal haemorrhage 7A Rockall, R F A Logan, H B Devlin,
T C Northfield, and the steering committee and members of the National Audit of Acute Upper Gastrointestinal
Haemorrhage
Coeliac disease
Reversal of osteopenia with diet in adult coeliac disease JT Valdimarsson, O Léfman, G Toss, M Strém
Gastrointestinal infection
Local entrapment of interferon y in the recovery from Shigella dysenteriae type 1 infection R Ragib, A Ljungdahi,
A A Lindberg, U Andersson, ¥ Andersson
Effect of Clostridium difficile toxin A on human intestinal epithelial cells: induction of interleukin 8 production and
apoptosis after cell detachment Y R Mahida, S Makh, S Hyde, T Gray, S P Borriello
In vivo IgA coating of anaerobic bacteria in human faeces LA van der Waatj, P C Limburg, G Mesander,
D van der Waaij
Contents
Inflammatory bowel disease
Platelet activating factor: release from colonic mucosa in patients with ulcerative colitis and its effect on colonic
secretion JD Wardle, L Hall, L A Turnberg
Smoking may prevent pouchitis in patients with restorative proctocolectomy for ulcerative colitis MM N Merrett,
N Mortensen, M Kettlewell, D P Fewell
Mucosal antibodies in inflammatory bowel disease are directed against intestinal bacteria A Macpherson,
U Y Khoo, I Forgacs, ¥ Philpott-Howard, I Bjarnason
Seasonal variations in the onset of ulcerative colitis B Moum, E Aadland, A Ekbom, M H Vatn
High frequency of helicobacter negative gastritis in patients with Crohn’s disease L Halme, P Karkkdinen,
H Rautelin, T U Kosunen, P Sipponen
Importance of antineutrophil cytoplasmic antibodies in primary sclerosing cholangitis and ulcerative colitis:
prevalence, titre, and IgG subclass DS Bansi, K A Fleming, RW Chapman
Immunology
Characterisation of inorganic microparticles in pigment cells of human gut associated lymphoid tissue
F F Powell, C C Ainley, R S ¥ Harvey, I M Mason, M D Kendall, E A Sankey, A P Dhillon, R P H Thompson
Gastrointestinal cancer
Effect of longterm placebo controlled calcium supplementation on sigmoidal cell proliferation in patients
with sporadic adenomatous polyps U M Wetsgerber, H Boeing, RW Owen, R Waldherr, R Raedsch,
JF Wahrendorf
p53 Tumour suppressor gene expression in pancreatic neuroendocrine tumour cells C Bartz, C Ziske,
B Wiedenmann, K Moelling
Folate status of gastrointestinal epithelial cells is not predicted by serum and red cell folate values in replete
subjects ¥~ Meenan, E O’Hallinan, S Lynch, A Molloy, } McPartlan, F Scott, D G Weir
Induction of NGAL synthesis in epithelial cells of human colorectal neoplasia and inflammatory bowel diseases
B S Nielsen, N Borregaard, ¥ R Bundgaard, S Timshel, M Sehested, L Kjeldsen
Family based colorectal cancer screening in a district hospital N P ¥ Cripps, R F Heald
K-ras gene mutation in gall bladder carcinomas and dysplasia JT Ayjiki, T Fujimori, H Onoyama, M Yamamoto,
S Kitazawa, S Maeda, Y Saitoh
Somatostatin analogue octreotide and inhibition of tumour growth in metastatic endocrine gastroenteropancreatic
tumours R Arnold, M E Trautmann, W Creutzfeldt, R Benning, M Benning, C Neuhaus, R Fiirgensen, K Stein,
H Schafer, C Bruns, H-¥ Dennler, and the German Sandostatin Multicentre Study Group
Liver
Metabolism of orally administered tauroursodeoxycholic acid in patients with primary biliary cirrhosis
K D R Setchell, C M P Rodrigues, M Podda, A Crosignani
Increased concentrations of tumour necrosis factor (TNF) and soluble TNF receptors in biliary obstruction in
mice; soluble TNF receptors as prognostic factors for mortality M H A Bemelmans, } W M Greve, D ¥ Gouma,
W A Buurman
Acute liver damage and ecstasy ingestion A F Ellis, ? A Wendon, B Portmann, Roger Williams
Special report
A national training programme for gastroenterology and hepatology M # G Farthing, R P Wait, R N Allan,
C H F Swan, I T Gilmore, C N Mallinson, 7 R Bennett, C ¥}H awkey, W R Burnham, A I Morris, C F Tibbs,
T E Bowling, C Cobb, S Catnach, C Farrell, A Towle
Personal viewpoint
M F S Langman
Letters to the editor Bookreviews Notes
No 4 APRIL 1996 Leading article
Ultrasound for gastroenterologists Derrick F Martin
Oesophagus
Natural history of reflux oesophagitis: a 10 year follow up of its effect on patient symptomatology and quality of
life N I McDougall, B T Fohnston, F Kee, ¥ S A Collins, R$ McFarland, A H G Love ,
Laparoscopic Nissen fundoplication — 200 consecutive cases DC Gotley, B M Smithers, M Rhodes, B Menzies,
F F Branichi, L Nathanson
Effect of acute stress on oesophageal motility in patients with gastro-oesophageal reflux disease B T Johnston,
R ¥ McFarland, 7 S A Collins, A H G Love
Helicobacter pylori
Induction of gastric epithelial apoptosis by Helicobacter pylori S F Moss, ¥ Calam, B Agarwal, S Wang,
P R Holt
Gastric mucosal superoxide dismutases in Helicobacter pylon infection ¥~ M Gétz, C I van Kan, H W Verspaget,
I Biemond, C B H W Lamers, R A Veenendaal
Expression of CD44 and its variants on gastric epithelial cells of patients with Helicobacter pylori colonisation
Xuejun Fan, Aideen Long, Michael Goggins, Xuegong Fan, P W N Keeling, Dermot Kelleher
Gastric metaplasia and duodenal ulcer disease in children infected by Helicobacter pylori S M Gormally,
B M Kierce, L E Daly, B Bourke, R Carroll, M T Durnin, B Drumm
Stomach
Effect of allopurinol, sulphasalazine, and vitamin C on aspirin induced gastroduodenal injury in human
volunteers M E McAlindon, A F Muller, B Filipowicz, C ¥ Hawkey
Relation of number of positive lymph nodes to the prognosis of patients with primary gastric adenocarcinoma
CW Wu, M C Hsieh, S S Lo, S H Tsay, W Y Lui, F K P’eng
Small intestine
Malignancy and survival in dermatitis herpetiformis: a comparison with coeliac disease P Collin, E Pukkala,
T Reunala
Comparative effects of dietary nucleoside-nucleotide mixture and its components on endotoxin induced bacterial
translocation and small intestinal injury in protein deficient mice A A Adjei, K Yamauchi, Y C Chan, M Konishi,
S Yamamoto
Inflammatory bowel disease
HLA class II gene frequencies in Crohn’s disease: a population based analysis in Germany M Reinshagen,
C Loeliger, P Kuehnl, U Weiss, B ¥ Manfras, G Adler, BO Boehm
Supplementary enteral nutrition maintains remission in paediatric Crohn’s disease M Wilschanski, P Sherman,
P Pencharz, L Davis, M Corey, A Griffiths
Contents
Leucocyte typing, cytokine expression, and epithelial turnover in the ileal pouch in patients with ulcerative colitis
and familial adenomatous polyposis PA Goldberg, F Herbst, C G Beckett, B Martelli, M Kontakou, I C Talbot,
P F Ciclitira, R F Nicholls
MUC2 is the prominent colonic mucin expressed in ulcerative colitis KM A F Tytgat, F 7 M Opdam,
A WC Einerhand, H A Biiller, 7D ekker
Soluble Fcy receptor III (CD16) and eicosanoid concentrations in gut lavage fluid from patients with
inflammatory bowel disease: reflection of mucosal inflammation D W Hommes, 7 Meenan, M de Haas,
F 7 W ten Kate, A E G Kr von dem Borne, G N F Tytgat, S ¥ H van Deventer
Butyrate enema therapy stimulates mucosal repair in experimental colitis in the rat 7 D Butzner, R Parmar,
C F Bell, V Dalal
Outcome of restorative proctocolectomy with ileal reservoir for ulcerative colitis: comparison of distal colitis with
more proximal disease D N Samarasekera, J F Stebbing, M G W Kettlewell, D P Jewell, NF} McC Mortensen
Large intestine
Sulindac induced regression of colorectal adenomas in familial adenomatous polyposis: evaluation of predictive
factors FM Giardiello, ¥ A Offerhaus, A C Tersmette, L M Hylind, A F Krush, 7 D Brensinger, S V Booker,
S R Hamilton
Effects of longterm epidermal growth factor treatment on the normal rat colon P Kissmeyer-Nielsen,
L Vinter-Fensen, M Smerup
Pathology of the rectal wall in solitary rectal ulcer syndrome and complete rectal prolapse Y S Kang,
M A Kamm, A F Engel, I C Talbot
Faecal phytic acid and its relation to other putative markers of risk for colorectal cancer R W Owen,
U M Weisgerber, B Spiegelhalder, H Bartsch
Decrease in sensitisation rate and intestinal anaphylactic response after nitric oxide synthase inhibition in a food
hypersensitivity model M 7 Fargeas, V Theodorou, B Weinch, ¥ Fioramonnu, L Buéno
Liver
Low dose a interferon therapy can be effective in chronic active hepatitis C. Results of a multicentre, randomised
trial ¥M Sanchez-Tapias, X Forns, S Ampurdanés, L Tité, R Planas, 7 M Viver, D Acero, M Torres, P Mas,
R Morillas, M Forné, ¥ Espinos, 7 M Liovet, ¥ Costa, E Olmedo, F X Lépez-Labrador, M T Fiménez de Anta, ¥ Rodeés
Natural history and prognostic factors in 305 Swedish patients with primary sclerosing cholangitis U Broome,
R Olsson, L Lééf, G Bodemar, R Hultcrantz, A Danielsson, H Prytz, H Sandberg-Gertzén, S Wallerstedt, G Lindberg
Case reports
Granulomatous hepatitis caused by Bacillus Calmette-Guerin (BCG) infection after BCG bladder instillation
F WG Leebeek, R ¥ Th Ouwendyk, A H F Kolk, A Dees, }C h E Meek, F E Nienhuis, A M Dingemans-Dumas
Colitis complicating chronic granulomatous disease. A clinicopathological case report FM Sloan,
C H S Cameron, R 7 Maxwell, D R McCluskey, ¥ S A Collins
A‘*-3-Oxosteroid 58-reductase deficiency: failure of ursodeoxycholic acid treatment and response to
chenodeoxycholic acid plus cholic acid P 7 Clayton, K A Mills, A W Johnson, A Barabino, M G Marazzi
Letters to the editor Bookreview Notes
British Association for the Study of the Liver
International Inflammatory Bowel Meeting
No 5 MAY 1996 Editorial
Gut moves towards the third millennium Michael Farthing
Leading articles
Why do cholestatic patients itch? EA Jones, N V Bergasa
Non-steroidal anti-inflammatory drugs and the chemoprevention of colorectal and oesophageal cancers
Gareth Morgan
Oesophagus
Relation between oesophageal acid exposure and healing of oesophagitis with omeprazole in patients with severe
reflux oesophagitis RH Holloway, 7 Dent, F Narielvala, A M Mackinnon
High amplitude contractions in the middle third of the oesophagus: a manometric marker of chronic alcoholism?
L Grande, R Monforte, E Ros, V Toledo-Pimentel, R Estruch, G Lacima, A Urbano-Marquez, C Pera
Stomach
Eradication of Helicobacter pylori in patients with duodenal ulcer lowers basal and peak acid outputs to gastrin
releasing peptide and pentagastrin A W Harns, P A Gummett, ¥ ¥ Misiewicz, 7 H Baron
Oxyntic endocrine cells of hypergastrinaemic patients. Differential response to antrectomy or octreotide
T D’Adda, B Annibale, G Delle Fave, C Bordi
Prevalence of metronidazole resistant Helicobacter pylori strains among Chinese peptic ulcer disease patients and
normal controls in Hong Kong C K Ching, K P Leung, RWH Yung, S K Lam, BC Y Wong, K C Lai, C L Lai
Small intestine
Influence of cell interactions in a novel model of postnatal mucosal regeneration H RH Patel, I S Tait,
G S Evans, F C Campbell
Acute epithelial injury in the rat small intestine in vivo is associated with expanded expression of transforming
growth factora andB A U Dignass, 7 L Stow, M W Babyatsky
Small intestinal motor abnormalities in patients with functional dyspepsia demonstrated by ambulatory
manometry H FA Jebbink, G P vanBerge-Henegouwen, L M A Akkermans, A ¥ P M Smout
Colon
Collagen alteration in an animal model of colonic diverticulosis LL Wess, M A Eastwood, C A Edwards, A Busuttil,
A Miller
Sulindac increases the expression of APC mRNA in malignant colonic epithelial cells: an in vitro study
M Schnitzler, T Dwight, B G Robinson
Smoking, hypertension, and colonic anastomotic healing; a combined clinical and histopathological study
A Fawcett, M Shembekar, 7 S Church, R Vashisht, R G Springall, D M Nott
Bile acid induced colonic irritation stimulates intracolonic nitric oxide release in humans’ F Casellas, M Mourelle,
M Papo, F Guarner, M Antolin, 7 R Armengol, ¥7-R Malagelada
Inflammatory bowel disease
Pathogenesis of aphthoid ulcers in Crohn’s disease: correlative findings by magnifying colonoscopy, electron
microscopy, and immunohistochemistry Y Fujimura, R Kamoi, M lida
Thrombotic vascular risk factors in inflammatory bowel disease M Hudson, A Chitolie, RA Hutton,
M S H Smith, R E Pounder, A ¥ Wakefield
Contents
Clinical patterns of familial inflammatory bowel disease ¥~ Satsangi, C Grootscholten, H Holt, D P Fewell
Pancreas
Acute ethanol administration induces oxidative changes in rat pancreatic tissue FE Altomare, I Grattagliano,
G Vendemiale, V Palmieri, G Palasciano
Lipopolysaccharide induced apoptosis of rat pancreatic acinar cells V ¥ O Laine, K M Nyman, H F Peuravuori,
K Henriksen, M Parvinen, T ¥ Nevalainen
Hyperlipaemia intensifies the course of acute oedematous and acute necrotising pancreatitis in the rat
B Hofbauer, H Friess, A Weber, K Baczako, P Kisling, M Schilling, W Uhl, C Dervenis, M W Biichler
Liver and biliary tract
Role of paraoesophageal collaterals and perforating veins on outcome of endoscopic sclerotherapy for oesophageal
varices: an endosonographic study RK Dhiman, G Choudhun, V A Saraswat, D K Agarwal, S R Naik
A duodenal mucosal abnormality in the reduction of Fe(IID) in patients with genetic haemochromatosis
K B Raja, D Pountney, A Bomford, R Przemioslo, D Sherman, R F Simpson, Roger Williams, T F Peters
Sclerotherapy versus sclerotherapy and propranolol in the prevention of rebleeding from oesophageal varices: a
randomised study SS Elsayed, G Shiha, M Hamid, F M Farag, F Azzam, M Awad
Roles of gall bladder emptying and intestinal transit in the pathogenesis of octreotide induced gall bladder stones
S H Hussaini, S P Pereira, M F Veysey, C Kennedy, P Jenkins, GM Murphy, 7 A H Wass, R H Dowling
Obstructive jaundice causes reduced expression of polymorphonuclear leucocyte adhesion molecules and a
depressed response to bacterial wall products in vitro S Plusa, N Webster, ¥ Primrose
Case report
Interchange between collagenous and lymphocytic colitis in severe disease with autoimmune associations
requiring colectomy: a case report JT E Bowling, A B Price, M Al-Adnam, P D Fairclough, N Menzies-Gow,
DBA Silk
Letters to the editor Bookreviews Notes Correction
Pancreatic Society of Great Britain and Ireland
No 6 JUNE 1996 Leading articles
Endoscopic retrograde cholangiopancreatography and acute pancreatitis A C De Beaux, D C Carter
Diverticular disease and chronic idiopathic inflammatory bowel disease: associations and masquerades
Neil A Shepherd
Oesophagus
Combination of laser treatment and intraluminal radiotherapy for malignant dysphagia E Shmueli, E Srivastava,
P 7 D K Dawes, M Clague, K Matthewson, C O Record
Influence of surgery on deglutitive upper oesophageal sphincter mechanics in Zenker’s diverticulum D W Shaw,
I ¥ Cook, G G Famieson, M Gabb, M E Simula, 7 Dent
Stomach
Audit of the outcome of peptic ulcer disease diagnosed 10 to 20 years previously ¥~ A Malliwah, M Tabagchali,
F Watson, C W Venables
Scintigraphic measurement of gastric emptying and ultrasonographic assessment of antral area: relation to
appetite K Hveem, K L Fones, B E Chatterton, M Horowitz
Non-ulcer dyspepsia and peptic ulcer: the distribution in a population and their relation to risk factors
The Sorreisa gastro-intestinal disorder study. B Bernersen, R Johnsen, B Straume
Sulphydryl blocker induced gastric damage is ameliorated by scavenging of free radicals F Karmeli, E Okon,
D Rachmilewitz
Effect of capsaicin and cimetidine on the healing of acetic acid induced gastric ulceration in the rat ¥ Y Kang,
C H Teng, F C Chen
B-cell clonality and infection with Helicobacter pylori: implications for development of gastric lymphoma
D Sorrentino, G F Ferraccioli, S DeVita, C Avellini, C A Beltrami, A Labombarda, V Bernardis, F De Biase, A Trevisi,
B Pivetta, M Botocchi, E Bartoli
Association of cytotoxin production and neutrophil activation by strains of Helicobacter pylori isolated from
patients with peptic ulceration and chronic gastritis QO B Zhang, I M Nakshabendi, M S Mokhashi, ¥ B Dawodu,
C G Gemmell, R I Russell
Small bowel
Changes in the enterocyte cytoskeleton in newborn rats exposed to ethanol in utero ¥ F Montes, G Estrada,
M D Lopez-Tejero, ¥ Garcia-Valero
Developmental differences in the expression of the cholera toxin sensitive subunit (Gsa) of adenylate cyclase in
the rat small intestine JR Sanderson, Z Xu, SW Chu, Q Y Xie, L F Levine, W A Walker
Effect of intestinal resection on human small bowel motility JT Schmidt, A Pfeiffer, N Hackelsberger, R Widmer,
C Meisel, H Kaess
Assessing the site of increased intestinal permeability in coeliac and inflammatory bowel disease K Teahon,
S Somasundaram, T Smith, I Menzies, I Bjarnason
Colon
Relations between transit time, fermentation products, and hydrogen consuming flora in healthy humans
L El Oufir, B Flourié, S Bruley des Varannes, } L Barry, D Cloarec,
F Bornet, ¥ P Galmiche
Effect of L-glutamine and n-butyrate on the restitution of rat colonic mucosa after acid induced injury
W Scheppach, G Dusel, T Kuhn, C Loges, H Karch, H-P Bartram, F Richter, S U Chnistl, H Kasper
Inflammatory bowel disease
Mucosal enzyme activity for butyrate oxidation; no defect in patients with ulcerative colitis ES Allan, S Winter,
A M Light, A Allan
Antineutrophil cytoplasmic antibodies in sera from colectomised ulcerative colitis patients and its relation to the
presence of pouchitis M Esteve, ¥#M allolas, #K laassen, A Abad-Lacruz, F Gonzdlez-Huix, E Cabre,
F Fernandez-Banares, X Bertran, E Condom,
¥$ Marti-Ragué, M A Gassull
Intracolonic administration of zileuton, a selective 5-lipoxygenase inhibitor, accelerates healing in a rat model of
chronic colitis .X Bertran, }M ané, F Fernandez-Banares, E Castella, R Bartoli, I Ojanguren, M Esteve,
MA Gassull
Predicting outcome in severe ulcerative colitis S PL Travis, ¥ M Farrant, C Ricketts, D ¥N olan, N M Mortensen,
M G W Kettlewell, D P Fewell
Role of interleukin 8 on leucoctye-endothelial cell adhesion in intestinal inflammation H Arndt,
MA Bolanowski, D N Granger
Contents
Nutrition
Attenuated GLP-1 secretion in obesity: cause or consequence? LR Ranganath, 7 M Beety, L M Morgan,
J W Wright, R Howland, V Marks
Nutrients and cyclical interdigestive pancreatic enzyme secretion in humans G Holtmann, D G Kelly,
E P DiMagno
Biliary tract
Biliary decompression promotes Kupffer cell recovery in obstructive jaundice W D B Clements, M McCaigue,
P Erwin, I Halliday, B ¥ Rowlands
Case report
Bleeding anorectal varices: successful treatment with transjugular intrahepatic portosystemic shunting (TIPS)
A C Fantin, G Zala, B Risti, ¥ F Debatin, W Schépke, C Meyenberger
Letters to the editor Book reviews Notes
Volume 38: Author Index —- Main Headings
Volume 38: Subject Index — Main Headings
Volume 38: Author Index —- Supplements 1 and 2
Volume 38: Subject Index - Supplements 1 and 2
Volume 38: Contents
‘+o tebe eii. se t 4¢
Z Ae} fz«‘ o twee ,
= “ 4 *eP e+ e
cae Ree
eBeiadkP e hsanoe s e By
akh+e a Meiae ey aesh far : eSpos d p3ie ye3rB st“o e
