Table Of Content

Center for Research on Genomics and Global Health Wrap Up Adebowale  Adeyemo,  MD   Deputy  Director,  Center  for  Research  on  Genomics  &  Global  Health   NHGRI/NIH   WT Genome Epidemiology Course, Durban, RSA – June 2015 Genome epidemiology •  Tools and Technology: high throughput genotyping and sequencing platforms, high performance computers, clusters and storage… •  Data and Databases: reference databases, genome browsers, central repositories of study data,… •  Analytic and Visualization Paradigms In this course: •  Genetic association studies •  Genome wide association studies (GWAS) •  Population genetics •  Meta-analysis of GWAS •  Sequencing •  Public resources •  Practicals: R, RStudio, plink, Linux •  Emphasis on process Published Genome-Wide Associations through 12/2012 Published GWA at p≤5X10-8 for 17 trait categories NHGRI GWA Catalog www.genome.gov/GWAStudies www.ebi.ac.uk/fgpt/gwas/ GWAS in Africa*: July 2013 *Does not include papers about selection, e.g. Alkorta-Aranburu et al PLoS Genetics 2012 More recent GWAS from Africa •  Mtatiro et al: Genome wide association study of fetal hemoglobin in sickle cell anemia in Tanzania. PLoS One. 2014 Nov 5;9(11):e111464. PubMed PMID: 25372704; PubMed Central PMCID: PMC4221031. •  Cook et al: A genome-wide association study of prostate cancer in West African men. Hum Genet. 2014 May;133(5):509-21. PubMed PMID: 24185611; PubMed Central PMCID: PMC3988225. •  Chimusa et al: Genome-wide association study of ancestry- specific TB risk in the South African Coloured population. Hum Mol Genet. 2014 Feb 1;23(3):796-809. doi: 10.1093/hmg/ddt462. PubMed PMID: 24057671; PubMed Central PMCID: PMC3888262. GWAS Catalog NHGRI GWAS Catalog is now the NHGRI-EBI GWAS of published genome wide association studies Now at http://www.ebi.ac.uk/gwas/ GWAS Catalog The NHGRI-EBI Catalog of published genome-wide association studies Search the catalog  Examples: breast cancer (search?query=breast%20cancer), rs7329174 (search?query=rs7329174), Yang (search?query=Yang), 2q37.1 (search?query=2q37.1), HBS1L (search?query=HBS1L)  About A description of the GWAS Catalog, including background and citation information. (docs/about) H3Africa Diseases/disorders from RHD to stroke ELSI Biorepositories Bioinformatics network Why an African GWAS array? Variants per genome MSL African-derived populations hVaarviaent sites / ESN Type YRI genome greater genetic diversity and lower LWK GWD ACB levels of LD, requiring a greater SNPs 3.78 million ASW density of SNPs to provide genome- PUR CLM MXL wide coverage of Incdoemls mon va57r3ia thtioounsa nd PEL KHV al CHB Mobile Element du Arrays optimizedIn sfeorrti oAnsfrican ~1066 ndivi CJDPXT I CHS populations derive content from BEB Large Deletions ~976 ITU HapMap/1000 Genomes African STU GIH populations and African-Americans/ PJL CNVs ~162 TSI Afro-Caribbeans/other African IBS CEU diaspora populations Inversions ~11 GBR FIN 3.8 4 4.2 4.4 4.6 4.8 5 5.2 Allele Count (Million) Variants per genome (1KG phase 3)

Description:
NHGRI GWA Catalog www.genome.gov/GWAStudies www.ebi.ac.uk/fgpt/gwas/. Published Genome-Wide Associations through 12/2012. Published GWA at p≤5X10-8 for 17 trait categories
ebook img

Genome-wide association study of ancestry- specific TB risk in the South African Coloured population PDF

19 Pages·2015·6.31 MB·English
by  
Save to my drive
Quick download
Download

Download Genome-wide association study of ancestry- specific TB risk in the South African Coloured population PDF Free - Full Version

by Unknow| 2015| 19 pages| 6.31| English

Download Genome-wide association study of ancestry- specific TB risk in the South African Coloured population by in PDF format completely FREE. No registration required, no payment needed. Get instant access to this valuable resource on PDFdrive.to!

Free Download PDF

About Genome-wide association study of ancestry- specific TB risk in the South African Coloured population

NHGRI GWA Catalog www.genome.gov/GWAStudies www.ebi.ac.uk/fgpt/gwas/. Published Genome-Wide Associations through 12/2012. Published GWA at p≤5X10-8 for 17 trait categories

Detailed Information

Author:Unknown
Publication Year:2015
Pages:19
Language:English
File Size:6.31
Format:PDF
Price:FREE
Download Free PDF

Safe & Secure Download - No registration required

Why Choose PDFdrive for Your Free Genome-wide association study of ancestry- specific TB risk in the South African Coloured population Download?

  • 100% Free: No hidden fees or subscriptions required for one book every day.
  • No Registration: Immediate access is available without creating accounts for one book every day.
  • Safe and Secure: Clean downloads without malware or viruses
  • Multiple Formats: PDF, MOBI, Mpub,... optimized for all devices
  • Educational Resource: Supporting knowledge sharing and learning

Free Books Similar to Genome-wide association study of ancestry- specific TB risk in the South African Coloured population

Frequently Asked Questions

Is it really free to download Genome-wide association study of ancestry- specific TB risk in the South African Coloured population PDF?

Yes, on https://PDFdrive.to you can download Genome-wide association study of ancestry- specific TB risk in the South African Coloured population by completely free. We don't require any payment, subscription, or registration to access this PDF file. For 3 books every day.

How can I read Genome-wide association study of ancestry- specific TB risk in the South African Coloured population on my mobile device?

After downloading Genome-wide association study of ancestry- specific TB risk in the South African Coloured population PDF, you can open it with any PDF reader app on your phone or tablet. We recommend using Adobe Acrobat Reader, Apple Books, or Google Play Books for the best reading experience.

Is this the full version of Genome-wide association study of ancestry- specific TB risk in the South African Coloured population?

Yes, this is the complete PDF version of Genome-wide association study of ancestry- specific TB risk in the South African Coloured population by Unknow. You will be able to read the entire content as in the printed version without missing any pages.

Is it legal to download Genome-wide association study of ancestry- specific TB risk in the South African Coloured population PDF for free?

https://PDFdrive.to provides links to free educational resources available online. We do not store any files on our servers. Please be aware of copyright laws in your country before downloading.

The materials shared are intended for research, educational, and personal use in accordance with fair use principles.

We use cookies

We use cookies to ensure you get the best browsing experience on our website. By clicking "Accept Cookies", you agree that we can store cookies on your device in accordance with our Terms and Privacy.