Frontiers in Human Genetics: Diseases and Technologies. Expanded and Updated Proceedings of the International Symposium on Human Genetics and Gene Therapy Held in Singapore 1999

422 Pages·2001·17.64 MB·English

by  Lai Poh San

FRONTIERS IN
HUMAN GENETICS
DISEASES AND TECHNOLOGIES

FRONTIERS IN
HUMAN GENETICS
DISEASES AND TECHNOLOGIES
With a Foreword from Lap-Chee Tsui
President of the Human Genome Organization (HUGO)
Expanded and Updated from the Proceedings of the
International Symposium on Human Genetics and Gene Therapy, Singapore
Editors
Lai Poh San, Coral
National University of Singapore
Eric P H Yap
Defence Medical Research Institute, Singapore
World Scientific
b
Singapore New Jersey. London Hong Kong
Published by
World Scientific Publishing Co. Pte. Ltd.
P 0 Box 128, Farrer Road, Singapore 91 2805
USA ofice: Suite lB, 1060 Main Street, River Edge, NJ 07661
UK oflice: 57 Shelton Street, Covent Garden, London WC2H 9HE
British Library Cataloguing-in-Publication Data
A catalogue record for this book is available from the British Library
FRONTIERS IN HUMAN GENETICS
Diseases and Technologies
Copyright 0 2001 by World Scientific Publishing Co. Pte. Ltd
All rights reserved. This book, or parts thereoJ may not be reproduced in any fiwm or by any means,
electronic or mechunical, including photocopying, recording or any information storage and retrieval
system now known or to be invented, without written permission from the Publisher.
For photocopying of material in this volume, please pay a copying fee through the Copyright
Clearance Center, Inc., 222 Rosewood Drive, Danvers, MA 01923, USA. In this case permission to
photocopy is not required from the publisher.
ISBN 981-02-4458-4
Printed in Singapore.
LIST OF CORRESPONDING AUTHORS
Thuan D. Bui
Membrane Biology Laboratory
Institute of Molecular and Cell Biology
30 Medical Drive
Singapore 1 17609
E-mail: dtbu i@ imcb.n us. edu.s g
Peh Yean Cheah
Department of Colorectal Surgery
Singapore General Hospital
Outram Road
Singapore 169608
E-mail: [email protected] om.s g
Betty,Cheng
BioInformatics Centre
National University of Singapore
Lower Kent Ridge Road
Singapore 1 19260
E-mail: [email protected] dusg
Eva Maria C. Cutiongco
Department of Paediatrics
University of the Philippines
College of Medicine
547 Pedro Gil Street
Ermita, Manila 1000
Philippines
E-mail: [email protected]
V
vi
Suthat Fucharoen
Thalassemia Research Center
Institute of Science and Technology for Research and Development
Mahidol University, Salaya Campus
25/25 M.3, Puttamonthon 4 Road
Puttamonthon, Nakornpathom 73 I70
Thai land
E-mail: [email protected]. th
Jiro Fujimoto
First Department of Surgery
Hyogo College of Medicine
Nishinomiya 663-850 1
Japan
E-mail: [email protected]
Leena A. Gole
Department of Obstetrics and Gynaecology
National University of Singapore
Lower Kent Ridge Road
Singapore I 19074
E-mail: obggolel@n us. edu.s g
Akinobu Gotoh
Department of Urology
Kobe University School of Medicine
7-5-2 Kusunoki-cho
Chuo-ku, Kobe 650-001 7
Japan
E-mail: gotoh@med. kobe-t4.ac.jp
vii
Kam Man Hui
Gene Vector Laboratory
Division of Cellular and Molecular Research
National Cancer Centre
11 Hospital Drive
Singapore 1696 10
E-mail: [email protected] orn.s g
Mohd. Nizam Isa
Human Genetics Unit
School of Medicine
Universiti Sains Malaysia
16 150 Kubang Kerian
Kelantan, Malaysia
E-mail:z am@kb. usrn.m y
Yasufumi Kaneda
Division of Gene Therapy Science
Graduate School of Medicine
Osaka University
Suita, Osaka 565-087 1
Japan
E-mail: kaneday@gts. med.O saka-u.a cjp
Pandjassarame Kangueane
BioInformatics Centre
#02-07 MD7 Medical Drive
National University of Singapore
Lower Kent Ridge Road
Singapore 1 19260
E-mail:k [email protected] us. edu.sg
viii
P.N.K antaputra
Department of Pediatric Dentistry
Faculty of Dentistry
Chiang Mai University
Chiang Mai 50200
Thailand
E-mail: dnpdi00 1@ chiangmai.ac.t h
Siok Im Koh
Chemical Process & Biotechnology Department
Singapore Polytechnic
500 Dover Road
Singapore 13965 1
E-mail: [email protected] dusg
Oi Lian Kon
Division of Medical Sciences
National Cancer Centre
11 Hospital Drive
Singapore 1696 10
E-mail: [email protected] omsg
Poh San Lai
Department of Paediatrics
National University of Singapore
Lower Kent Ridge Road
Singapore 1 19074
E-mail: [email protected] dusg