FORMULATION AND EVALUATION OF DELAYED RELEASE TABLETS OF RABEPRAZOLE

121 Pages·2015·6.86 MB·English

FORMULATION AND EVALUATION OF DELAYED RELEASE TABLETS OF
RABEPRAZOLE SODIUM

A Dissertation Submitted to
THE TAMIL NADU DR. M.G.R MEDICAL UNIVERSITY
CHENNAI – 600032
In partial fulfillment of the requirements for the award of the Degree of

MASTER OF PHARMACY
IN
BRANCH - I - PHARMACEUTICS

Submitted by
VIJAYANAND. M
REG. No. 261510355

Under the guidance of
Mr. L. SUBRAMANIAN, M. Pharm., (Ph. D.,)
Associate Professor
DEPARTMENT OF PHARMACEUTICS

SANKARALINGAM BHUVANESWARI COLLEGE OF PHARMACY
ANAIKUTTAM, SIVAKASI – 626130.
OCTOBER – 2017
CERTIFICATES

Mr.L.Subramanian, M.Pharm., ( Ph.D.,)
Associate Professor,
Department of Pharmaceutics,
Sankaralingam Bhuvaneswari College of Pharmacy,
Anaikuttam, Sivakasi – 626130
Tamil Nadu.

CERTIFICATE BY THE GUIDE
This is to certify that the dissertation entitled, “Formulation and Evaluation of Delayed
Release Tablets of Rabeprazole Sodium” submitted by M.Vijayanand (Reg.No.
261510355) to The Tamil Nadu Dr. M.G.R Medical University, Chennai, for the award of
the degree of “Master of Pharmacy in Pharmaceutics” is a bonafide research work
carried out by him partially in Pharma fabrikon, vilathur, Madurai, under the
supervision of Mr. R. Venkadesh Babu, M.Pharm., Manager, Research and
Development Department and partially in the Department of Pharmaceutics,
Sankaralingam Bhuvaneswari College of Pharmacy, Sivakasi, under my guidance and
supervision.The content of this dissertation in full or in parts have not been submitted to
any other Institute or University for the award of any degree or diploma.

Place: Sivakasi Mr. L. Subramanian, M.Pharm. (Ph.D)
Date:
Dr. M. Rajesh, M.Pharm., Ph.D.,
Professor and Head,
Department of Pharmaceutics,
Sankaralingam Bhuvaneswari College of Pharmacy,
Anaikuttam, Sivakasi – 626130
Tamil Nadu.

CERTIFICATE BY THE HEAD OF THE DEPARTMENT
This is to certify that the dissertation entitled, “Formulation and Evaluation of Delayed
Release Tablets of Rabeprazole Sodium” submitted by M.Vijayanand (Reg.No.
261510355) to The Tamil Nadu Dr. M.G.R Medical University, Chennai, for the award of
the degree of “Master of Pharmacy in Pharmaceutics” is a bonafide research work
carried out by him partially in Pharma fabrikon, vilathur, Madurai, under the
supervision of Mr. R. Venkadesh Babu, M.Pharm., Manager, Research and
Development Department and partially in the Departmentof Pharmaceutics,
Sankaralingam Bhuvaneswari College of Pharmacy, Sivakasi, under the guidance and
supervision of Mr.L.Subramanian, M.Pharm., ( Ph.D.,). The content of this
dissertation in full or in parts have not been submitted to any other Institute or University
for the award of any degree or diploma.

Place: Sivakasi Dr. M. Rajesh M.Pharm., Ph.D.,

Date:
Dr. P. Solairaj, M.Pharm., Ph.D.,
Principal,
Sankaralingam Bhuvaneswari College of Pharmacy,
Anaikuttam, Sivakasi – 626130
Tamil Nadu.

ENDORSEMENT BY THE PRINCIPAL
This is to certify that the dissertation entitled, “Formulation and Evaluation of Delayed
Release Tablets of Rabeprazole Sodium” submitted by M.Vijayanand (Reg.No.
261510355) to The Tamil Nadu Dr. M.G.R Medical University, Chennai, for the award of
the degree of “Master of Pharmacy in Pharmaceutics” is a bonafide research work
carried out by him partially in Pharma fabrikon, vilathur, Madurai, under the
supervision of Mr. R. Venkadesh Babu, M.Pharm., Manager, Research and
Development Department and partially in the Departmentof Pharmaceutics,
Sankaralingam Bhuvaneswari College of Pharmacy, Sivakasi, under the guidance and
supervision of Mr.L.Subramanian, M.Pharm., ( Ph.D.,) .The content of this
dissertation in full or in parts have not been submitted to any other Institute or University
for the award of any degree or diploma.

Place: Sivakasi Dr. P. Solairaj M.Pharm., Ph.D.,
Date:
SANKARALINGAM BHUVANESWARI COLLEGE OF PHARMACY,
ANAIKUTTAM, SIVAKASI – 626130

GUIDE, HEAD OF THE DEPARTMENT AND PRINCIPAL CERTIFICATE

This is to certify that the dissertation entitled, “Formulation and Evaluation of Delayed
Release Tablets of Rabeprazole Sodium” submitted by M.Vijayanand (Reg.No.
261510355) in the Department of Pharmaceutics, Sankaralingam Bhuvaneswari College of
Pharmacy, Sivakasi in partial fulfillment of the university rules and regulations for the
award of “MASTER OF PHARMACY IN PHARMACEUTICS” during the academic
year 2016 - 2017.

Name & Signature of the Guide:

Name & Signature of the Head of the Department:

Name & Signature of the Principal:
EVALUATION CERTIFICATE

This is to certify that the dissertation entitled, “Formulation and Evaluation of Delayed
Release Tablets of Rabeprazole Sodium” submitted by M.Vijayanand (Reg.No.
261510355) to The Tamil Nadu Dr. M.G.R Medical University, Chennai, for the award of
the degree of “Master of Pharmacy in Pharmaceutics” was evaluated by us during the
academic year 2016 – 2017.

Internal Examiner External Examiner
Date: Date:
ACKNOWLEDGEMENT
ACKNOWLEDGEMENT
Behind every successful venture, it is always said that there is an invisible force,
which shapes things in the right way and directions in which they should be. I found it my
moral duty to bow to that driven power and thank Almighty for imbibing in me the
strength required for the successful completion of this dissertation work.
As someone said, the future belongs to those who believe in the beauty of their
dreams and I place my cordial thanks to my Parents for giving me the opportunity to
make my dreams come true and for their love without which I couldn’t have reached this
place.
I express my special thanks to our honorable Correspondent Mr. S. Sriram
Ashok, B.E., for providing necessary facilities in the college campus to carry out this
dissertation work successfully.
First and foremost, I express my gratitude and sincere regards to my institutional
guide Mr. L. Subramanian, M.Pharm., (Ph.D)., Professor in Department of
Pharmaceutics whose sincerity and encouragement had made this work successful. I thank
his guidance and scrutiny of documents with attention and care.
I take this golden opportunity to express my humble gratitude and respect to my
industrial guide Mr. R. Venkadesh Babu, M.Pharm., Manager, Research and
Development, Pharma fabrikon, vilathur, Madurai and I am thankful for his valuable
guidance, encouragement, timely help and support during my dissertation.
It is an honour to pay my respect and heartfelt thanks to Dr. P. Solairaj,
M.Pharm., Ph.D., Principal of our esteemed Institution for his valuable guidance,
encouragement and fruitful suggestion to make my work worthy of presentation.
I am equally thankful to Dr. R. Sutharsingh, M.Pharm., Ph.D., Vice Principal
for his help and suggestions during my dissertation work.
I express my heartfelt thanks to Dr. S.Palanichamy, M.Pharm., Ph.D., Director
and Professor, Department of Pharmaceutics for their valuable encouragement and
support offered during my dissertation work.