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AssociCaltien iPcraolf esosfMo erd iciannedP ediatrics
ChieSfe,c tioofAn l leragnydI mmunology
DepartmoefnM te dicine
UniverosfiL toyu isville
VIKABS HUSHANM,D
DiagnosRtaidci ologist
LosA ngeles
VIVETK. K ULKARNI
YalSec hooolfM edicine
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MATTHEWM .S OCHAT
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1 2 3 4 5 6D O7W / 8D O9W1 401 31 2
ISB9N7 8-0-07-180232-1
MHI0D- 07-180232-0
ISS1N5 32-6020
Notice
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Dedication
Tot hceo ntritbotu htaionsrdp s a setd itiwohnots o,ot ki mteos hare
thekinro wleidngseia,gn hdht u,m ofrot rh bee neoffsi ttu dents.
Contents
ContribuAtuitnhgo rs vii Howt oC ontribute XVII
AssociAautteh ors viii Howt oU seT his Book xix
FaculRteyv iewers ix CommonU SMEL LaboratVoarlyu es XXI
Preface xi BasiScc ienDcies cipClrionses -Reference
Tablfeo Hri gh-YFiaecltds xxiii
SpeciAaclk nowledgments xii
FirAsitdC hecklfiostrth eU SMEL Ste1p xxiv
AcknowledgmfeonOrtn sl iCnoen tributors xiii
�SECTIOIN GUIDET O EFFICINET EXAM PREPARATION 1
Introduction 2 CliniVciagln eStttrea tegies 21
USMLSEt e1p- TheB asics 2 IYfo uT hinYko uF ailed 22
DefinYionugGr o al 12 IYfo uF ailed 22
TimelfionSert udy 12 TestiAngge ncies 23
StudMya terials 17 References 23
Test-TaSktirnagt egies 19
�SECTIOINS UPPLEMENT SPECIASLI TUATIONS 25
FirAsitdf otrh eI nternatMieodniacGlar la duate 26 FirAsitdf otrh eP odiatMreidci cSatlu dent 41
FirAsitdf otrh eO steopaMtehdiicc Satlu dent 36 FirAsitdf otrh eS tudewnitt ah D isability 43
�SECTIOINI HIGH-YIELDG ENERAL PRINCIPLES 45
Howt oU set heD atabase 46 Immunology 191
Behavioral Science 49 Pathology 211
Biochemistry 63 Pharmacology 225
Microbiology 117
v
�SECTION Ill HIGH-YIELODR GAN SYSTMES 245
Cardiovascular 249 Psychiatry 457
Endocrine 285 Renal 477
Gastrointestinal 307 Reproduc,t ive 503
HematolaongdyO ncology 343 Respiratory 543
MusculoskeSlkeitna,l C,ao nndn ectTiivses ue 377 RapiRde view 565
Neurology 407
�SECTIONI V TOP-RATEDR EVIEWR ESOURCES 583
Howt oU set heD atabase 584 MicrobioalnodIg mym unology 601
IJ
QuestiBoann ks 586 Pathology 605
QuestiBoono ks 587 Pharmacology 610
Internet Sites 588 Physiology 614
Comprehensive 589 CommercRieavli eCwo urses 619
AnatomEym,b ryolaongdyN ,e uroscience 591 Publisher Contacts 624
BehavioSrcaile nce 595 AbbreviaatnidoS nysm bols 625
Biochemistry 597 PhotAoc knowledgments 633
CelBli oloagnydH istology 599
Index 641 Aboutth eA uthors 695
VI
ContrbiutnigA uthros
JACOBB ARANOSKI MAX C.P ETERSEN
MedicSacli enTtriasitn ing Program
YalSec hoooflM edicine
YalSec hoooflM edicine
Claosfs2 014
ROBERTS TRETCH
VICKZI. J .B ING
YalSec hoooflM edicine
YalSec hoooflM edicine
Claosfs2 014
Claosfs2 014
GARTHS TROHBEHN
JEFFRESY.F UTTRELEIB
YalSec hoooflM edicine
YalSec hoooflM edicine Claosfs2 014
Claosfs2 013
NICHOLATSH EODOSAKIS
ABHIJEEGTU MMADAVELLI
Medical Scientist Training Program
YalSec hoooflM edicine YalSec hoooflM edicine
Claosfs2 014
RICHARDP .U SATINEMD,
LAURENH IBLER DermatoIlmoaggyeC so ntributor
ProfesDseorrm,a toalnodgC yu taneSouursg ery
YalSec hoooflM edicine
ProfesFsaomria,ln ydC ommuniMteyd icine
Claosfs2 014
UniverosfTi etxyaH se alStchi enCceen tSearn A ntonio
JEFFREHYO FMANN CAROLINAE. W ALKER
WarrAelnp eMretd icSaclh oooflB rowUnn iversity YalSec hoooflM edicine
Claosfs2 016 Claosfs2 014
OLGAL AUR SAMANTHAX .Y .W ANG
YalSec hoooflM edicine YalSec hoooflM edicine
Claosfs2 014 Classo f2 014
WALTER WFI.G GINSP,h D
KELSEBY. L OELIGER
Editfoirr,s taidteam.com
MedicSacli enTtriasitnP irnogg ram
WakeF oreSscth oooflM edicine
YalSec hoooflM edicine
Classo f2 014
GORANM ICEVIC PETERZ HAO
MedicSacli enTtriasitnP irnogg ram YalSec hoooflM edicine
YalSec hoooflM edicine Classo f2 014
VII
AssoctieaA uthors
FADYA KLADIOS AMY MORENO
MedicUanli verosfti hteAym ericas YalSec hoooflM edicine
Claosfs2 013 Claosfs2 014
ADITYBAA RDI,AM D,M PH
AYESHAN ZERIBE
AttendPihnygs icMiaasns,a chuGseentetrsHa ols piCtaanlc Ceern ter
WarrAelnp eMretd icSaclh oooflB rowUnn iversity
InstruicntM oerd iciHnaer,v aMredd icSaclh ool
Claosfs2 013
MICHELLME. B RAVO
KEZIAS PENCE
WarrAelnp eMretd icSaclh oooflB rowUnn iversity
Claosfs2 013
WarrAelnp eMretd icSaclh oooflB rowUnn iversity
Claosfs2 013
RAFAELA .B UERBA
YalSec hoooflM edicine RANYWOO
Claosfs2 014
YalSec hoooflM edicine
Claosfs2 013
JONATHAN FU
YalSec hoooflM edicine
Claosfs2 013 ANDREW HANOIW U
BostUonni verSscihtoyoo flM edicine
ALEJANDRROA FAELG ENER Claosfs2 015
UniversCiednatddr eaClla ribe
Claosfs2 015
MICHAELX IONG
ASHWANIG ORE WarrAelnp eMretd icSaclh oooflB rowUnn iversity
Claosfs2 015
StG.e orgUen'isv erSscihtoyoo flM edicine
Claosfs2 015
PATRICIZAA DNICK
JAMESM . GRAY
JohnHso pkiSncsh oooflM edicine
UniverCsoiltlyeD gueb lSicnh oooflM edicainndeM edicSacli ence Claosfs2 014
Claosfs2 014
CHRISTINZEE NDER-PRINCETDOON ,
WILLIALM .H WANG,M Sc
ResidPehnyts icLiaakne,l Raengdi oHneaall thcare
HealStchi en&cT eesc hnolaongdByi o physics Programs
AdjunPcrto fesCsloirn,i cal
HarvaUrndi versity/MasIsnascthioutfTsu eetcteht nso logy
MichiSgtaanUt nei verCsoiltlyeo gfMe e dicine
MD/PhcDa ndidate
KATHARINJEO O JINY(UJ ANEZ)H ANG
Warren Alpert MeodfBi rcoawlUn n Sicvheorosli ty WarrAelnp eMretd icSaclh oooflB rowUnn iversity
Claosfs2 013 Claosfs2 014
VIII
Faculty
Reviewers
SHANTAK APADI,AM D
CHARLEDSE LAC RUZ,M D
AssisPtraonfte sDseopra,r tmoefPn utl monaanrdyC ritCiacraMele dicine LecturDeerp,a rtmoefSn utr gery
YalSec hoooflM edicine YalSec hoooflM edicine
EMILYR .E SPOSITPOh,D BERTRAMK ATZUNGM,D ,P hD
AssisPtraonfte ssor ProfesEsmoerr itus
SulliUvnainv erCsoiltlyeo gfPe h armacy UniverosfCi atlyi foSrannFi raa,n cisco
CONRADF ISCHEMRD,
GERALDL EEM,D
AssociPartoef esofsP ohry siolMoegdyi,c iannedP, h armacology
AssisPtraonfte sSseocrt,io ofAn l learngdyI mmunology
TourCoo lleogfMe e diciNneew,Y orCki ty
DepartmeonfIt n terMneadli cine
UniverosfLi otuyi sSvcilhlooeof lM edicine
STUARTFL YNN,M D
Dean, CoolfMl eedgiec ine WARRENL EVINSONM,D ,P hD
TheU niverosfAi rtiyz oPnhao,e nix
Professor, DoefpM airctrmoebniaton ldoI gmym unology
UniverosfCi atlyi foSrannFi raa,n cisco
ANUJG AGGAR,M D
Clinical Fellow
NICHOLASM AHONEY,M D
DepartmoefIn ntf ectDiiosuesa se
UniverosfSi atnFy r anciSscchooo oflM edicine AssisPtraonfte sDseopra,r tmoefOn pth thalmology
WilmeEry eI nstitutHeo/pJkoihUnnnssi versity
MATTHEWG ARABEDIA,NM D
DivisoifMo ant ernalM-eFdeitcailn e PETERM ARKS,M D,P hD
DepartmoefOn bts tetarnidGc ysn ecology
Associate PDreopfaertsmseoonfrIt ,n terMneadli cine
SantCal aVraal lMeeyd icCaeln ter
YalSec hoooflM edicine
ANTHONYG LASERM,D ,P hD
PATRICIJA.M ElTINGP,h D
Assistant ProfessoofFr a,m iDMleeypd airctimneen t
MedicUanli verosfSi otuytC ha rolina ProfesosfPo hry sio&l Pohgayr macoalnodog fyM edicine
VicCeh ancealnldoS re niAosrs ociDaetaenf oSrt udeAnffta irs
RYANC .W .H ALLM,D TheU niverosfTi otlye Cdool leogfMe e diciannedL ifSec iences
AssisPtraonfte sDseopra,r tmoefMn etd icEadlu cation
AFSOONM OKTAR,P hD
UniverosfCi etnyt rFallo rOirdlaa,n do
AffilAisastiesP traonfte sDseopra,r tmoefPn sty chiatry
AssisPtraonfte ssor
UniverosfSi otuytF hl orTiadmap,a
SulliUvnainv erCsoiltlyeo gfPe h armacy
RAJESHJ ARIM,D ,M BA
ROBERTN OVAK,M D
Spine, MeadnidRc eihnaeb,i litation ThePraaiMnpa ineasg-eSmMeAnRtT
ChaiDre,p artmoefPn att holaongdLy a boraMteodryi cine
WestminasntdWe hri tMea rsMha,r yland
AkroCnh ildrHeons'psi tal
KURTJ OHNSON,P hD
DAVIDP ERR,YP hD
ProfesDseopra,r tmoefAn nta toamnyd R egenerBaitoilvaoeng dy
DepartmoefOn bts tetarnidGc ysn ecology ProfesDseopra,r tmoefPn hta rmacoalnodPg hyy siology
GeorgWea shingUtnoinv erSscihtyo ooflM edicine GeorgWea shingUtnoinv erSscihtoyoo flM edicine
IX
MICHAESL. R AFI,IM D,P hD HOWARD STEINMANP,h D
DirecMteomro,r Dyi sordCelrisn ic ProfesDseopra,r tmoefBn ito chemistry
AssisPtraonfte sosfNo eru rosciences AssisDteaanont f B iomediSccaile nEcdeu cation
UniverosfCi atyl iifao SrannD iegHoe alStyhs tem AlbeEritn stCeoilnl eogfMe e dicine
STEPHENT HUNG,M D
DANIEJL. R UBINM,D ,M SC AssociPartoef esDseopra,rt meonfOt b stetrics/Gynecology
OhiSot aUtnei versity
AssisPtraonfte sosfMo erd iciDniev,i soifEo nnd ocrinology
AssociPartoeg rDaimr ecEtnodro,c rinFoellolgoyw ship
TemplUen iverSscihtoyoo flM edicine RICHARDP .U SATINMED,
ProfesDseorrm,a toalnodgCy u taneSouursg ery
ProfesFsaomria,ln ydC ommuniMteyd icine
JOSEPHSC HINDLEMRD, UniverosfTi etxyaH se alStchi enCceen tSearnA n tonio
AssisPtraonfte sDseopra,r tmoefNn etu rolaongdNy e urosurgery
HILARYV ERNON,M D
ClinDiicraelc YtaolrNe,e wH aveSnt roPkreo gram
YalSec hoooflM edicine AssisPtraonfte sMscoKru,s ick-NInastthiatnousfGt een etMiecd icine
JohnHso pkiUnnsi versity
SANJISVH AH,M D ADAM WEINSTEIMND,
AssisPtraonfte sDsiovri,so ifCo anr diology AssisPtraonfte sSseocrt,io ofPn e diaNterpihcr ology
DepartmoefMn etd icine DepartmeonfPt e diatrics
NorthwesUtneirvne rsity GeisSeclh oooflM ediciantDe a rtmouth
X
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