Table Of ContentT Y
The Proceedings of the Xlth World Congress on Fertility and Sterility,
Dublin, June 1983, held under the Auspices of the International
Federation of Fertility Societies
Edited by
R.F. Harrison
J.
Bonnar W.Thompson
~ .MTP PRESS LI.MITED "
~ a member of the KLUWER ACADEMIC PUBLISHERS GROUP
LANCASTER / BOSTON / THE HAGUE / DORDRECHT
Published in the UK and Europe by
MTP Press Limited
Falcon House
Lancaster, England
British Library Cataloguing in Publication Data
Advances in fertility control and the treatment of sterility.
1. Contraception-Congresses
I. Rolland, R. II. Harrison, R. F.
III. Bonnar, J. IV. Thompson, William, 1937-
V. World Congresses on Fertility and Sterility (11th: 1983:
Dublin)
613.9'4 RG136
ISBN 978-94-015-1310-4
Published in the USA by
MTP Press
A division of Kluwer Boston Inc
190 Old Derby Street
Hingham, MA 02043, USA
Library of Congress Cataloging in Publication Data
Main entry under title:
Advances in fertility control and the treatment of sterility.
Bibliography: P.
Includes index.
1. Oral contraceptives - Congresses. 2. Infertility, Female -
Treatment - Congresses. I. Rolland, R. II. World Congress of
Fertility and Sterility (11th: 1983: Dublin, Dublin) [DNLM:
1. Fertility - Congresses. 2. Infertility - Therapy - Congresses.
3. Contraceptives, Oral - Congresses. QV 177 A244 1983]
RG137.5.A381983 618.1'78 83-22258
ISBN 978-94-015-1310-4 ISBN 978-94-015-1308-1 (eBook)
DOI 10.1007/978-94-015-1308-1
Copyright © 1984 MTP Press Limited
Softcover reprint of the hardcover 1st edition 1984
All rights reserved. No part of this publication
may be reproduced, stored in a retrieval
system, or transmitted in any form or by any
means, electronic, mechanical, photocopying,
recording or otherwise, without prior permission
from the publishers.
Phototypesetting by Titus Wilson, Kendal
Published in the UK and Europe by
MTP Press Limited
Falcon House
Lancaster, England
British Library Cataloguing in Publication Data
Advances in fertility control and the treatment of sterility.
1. Contraception-Congresses
I. Rolland, R. II. Harrison, R. F.
III. Bonnar, J. IV. Thompson, William, 1937-
V. World Congresses on Fertility and Sterility (11th: 1983:
Dublin)
613.9'4 RG136
ISBN 0--85200-768-X
Published in the USA by
MTP Press
A division of Kluwer Boston Inc
190 Old Derby Street
Hingham, MA 02043, USA
Library of Congress Cataloging in Publication Data
Main entry under title:
Advances in fertility control and the treatment of sterility.
Bibliography: P.
Includes index.
1. Oral contraceptives - Congresses. 2. Infertility, Female -
Treatment - Congresses. I. Rolland, R. II. World Congress of
Fertility and Sterility (11th: 1983: Dublin, Dublin) [DNLM:
1. Fertility - Congresses. 2. Infertility - Therapy - Congresses.
3. Contraceptives, Oral - Congresses. QV 177 A244 1983]
RG137.5.A381983 618.1'78 83-22258
ISBN 0--85200-768-X
Copyright © 1984 MTP Press Limited
All rights reserved. No part of this publication
may be reproduced, stored in a retrieval
system, or transmitted in any form or by any
means, electronic, mechanical, photocopying,
recording or otherwise, without prior permission
from the publishers.
Phototypesetting by Titus Wilson, Kendal
Contents
Preface xiii
List of Contributors xv
Inaugural address: trends and prospects for research on fertility
and sterility in the 1980s
A. Kessler 1
PART I: MAIN THEMES OF THE CONGRESS
Section 1: Neuro-endocrinology - Reproductive Releasing Hormones
1 Mechanisms regulating LHRH release: implications for
fertility regulation
A. Negro-Villar 15
2 Medical castration in men: the first clinical application
of LHRH agonists
F. Labrie, A. Belanger, A. Dupont and R. St-Arnaud 25
3 Reproductive releasing hormones - the future
J. Sandow 41
Section 2: Prediction and Detection of Ovulation
4 The physiological basis of the fertile period
H. G. Burger 51
5 Biochemical methods for predicting ovulation
W. P. Col/ins, H. N. Sal/am, L. E. M. Schiphorst and P.
Royston 59
v
FERTILITY AND STERILITY
6 Ultrasound and follicular development
S. Nitschke-Dabelstein 71
7 Methods of identifying the fertile period
J. Bonnar 77
8 A critical review of natural family planning studies
J. M. Spieler 93
Section 3: Fertilization in vitro and in vivo
9 Current status of human in vitro fertilization
R. G. Edwards 109
10 Events leading to fertilization in mammals
P. Talbot 121
11 Early human embryology
R. O'Rahilly and F. Maller 133
12 Organization of an in vitro fertilization programme
A. A. Acosta, J. Garcia, C. E. S. Jones, L. Veeck, B. Sandow
and H. W. Jones 139
13 Clinical experiences with in vitro fertilization and embryo
transfer programmes
W. Feichtinger and P. Kemeter 145
Section 4: Tubal Factors in' Reproduction
14 Physiology of tubal function
E. M. Coutinho 157
15 The epidemiology of salpingitis
W. Thompson 163
16 Pelviscopic therapy for tubal disease
K. Semm 175
17 Prevention of postoperative adhesions
W. H. Utian 189
Section 5: Immunology and Reproduction
18 Immunological aspects of implantation
K. Tsubata, H. Nakamura, Y. Tsukahara, E. Kawaguchi,
T. K. Fujii and S. Takagi 203
vi
FERTILITY AND STERILITY
19 The nature of the placental immunological barrier
T. G. Wegmann 207
20 Detection of immunoreactive materials in body fluids
K. Brogaard Hansen and T. Hjort 215
21 Immunological methods of birth control
v. C. Stevens 223
22 Treatment of immunologically conditioned infertility
W. R. Jones 233
Section 6: Male Fertility
23 Epididymal function
G. F. Menchini-Fabris, P. L. 1zzo, M. Bartelloni, P. Meschini
and D. Canale 245
24 Gossypol
M. R. N. Prasad and E. Diczfalusy 255
Section 7: New Approaches to Female Fertility Regulation
25 New approaches to female fertility regulation - an over
view
S. S. Ratnam and R. N. V. Prasad 271
26 Recent progress in the use of copper IUDs
A. J. M. Audebert 291
27 Steroid-releasing vaginal rings: a review
P. J. Rowe 301
28 Postcoital contraception: experiences with ethinyloestra
diollnorgestrel and levonorgestrel only
K. O. K. Hoffmann 311
Section 8: Lactation and Birth Spacing
29 Lactation and birth spacing: an overview
M. A. BeIsey 319
30 Clinical, hormonal and ultrasonic indicators of returning
fertility after childbirth
A. M. Flynn, S. S. Lynch, M. Docker and R. Morris 325
vii
FERTILITY AND STERILITY
31 Steroidal contraception and lactation
Prema Rhamachadran 337
32 Birth intervals - demographic factors
S. Teper 351
Section 9: Psychosocial Aspects of Reproduction
33 The infertile couple and the gynaecologist: psychosocial
and emotional aspects
E. V. van Hall 359
34 Stress in infertile couples
R. F. Harrison, A. M. O'Moore, R. R. O'Moore and D. Robb 369
35 Psychosexual problems in infertility
A. D. G. Brown 377
36 Problems of adoption
L. Lefroy 385
37 Psychosocial aspects of fertility control
T. Standley 397
Section io: Social and Demographic Problems of Fertility
38 Social and political factors in fertility control
E. M. Martin 407
39 Population trends and prospects
L. Kegan 411
40 Fertility, population and development
A. McCormack 417
PART II: WORKSHOPS
41 Workshop on the standardized investigation of the
infertile couple
Moderator: P. Rowe
Co-ordinator: M. Darling 427
42 Monoclonal antibodies in human reproduction
Moderators: L. Mettler and P. M. Johnson
Co-ordinator: K. Hannon 443
viii
FERTILITY AND STERILITY
43 Therapeutic approaches to male infertility
Moderator: J. P. Pryor
Co-ordinator: P. O'Donovan 449
44 Artificial insemination
Moderator: C. D. Matthews
Co-ordinator: A. I. Traub 453
45 Luteal-phase insufficiency
Moderator: I. D. Cooke
Co-ordinator: N. Heasley 457
46 Secondary infertility
Moderator: S. Robertson
Co-ordinator: R. F. Harrison 461
47 Sexually transmitted diseases and infertility
Moderator: W. Cates, Jr.
Co-ordinator: P. McKenna 465
48 Genetics in reproduction
Moderator: N. Nevin
Co-ordinator: N. O'Hanrahan 469
49 Occupational hazards in reproductive health
Moderator: M. J. Rosenberg
Co-ordinator: M. Moloney 473
50 Principles of training in human reproduction
Moderator: M. Elstein
Co-ordinator: G. Oyakhire 475
PART III: SPECIAL SYMPOSIA
Section 1: Prolactinomas and Pregnancy
51 Introduction
H. S. Jacobs 485
52 Medical investigation of abnormal prolactin states
P. G. Crosignani, C. Ferrari, P. Rampini, P. Adelasco,
C. Zavaglia, G. Brambilla, M. Boghen and A. Paracchi 489
ix
FERTILITY AND STERILITY
53 Neuroradiology of prolactinomas
K. Hall 497
54 The outcome of pituitary exploration in patients with
hyperprolactinaemic infertility
G. Teasdale, A. Richards, R. Bullock and J. Thomson 509
55 Medical treatment of prolactinomas
S. Franks and H. S. Jacobs 515
56 Surveillance of Parlodel (bromocriptine) in pregnancy
and offspring
P. Krupp and I. Turkalj 521
57 Prolactinomas in pregnancy
T. Bergh and S. J. Nillius 527
Section 2: Advances in Fertility Control and Treatment of Sterility
58 Pre-treatment evaluation of ovarian infertility
G. Bettendorf 535
59 Hyperprolactinaemic infertility: some considerations on
medical management
M. O. Thorner, M. L. Vance and R. M. Macleod 547
60 Lisuride - a new drug for treatment of hyperpro
lactinaemic disorders
R. Horowski, R. Dorow, A. Scholz, L. de Cecco and W. H. F.
Schneider 561
61 Benefits and risks of hormonal contraception - interpret
ation
M. Smith 575
62 Towards safer oral contraception
C. R. Kay 581
63 The influence of the triphasic pill and a desogestrel
containing combination pill on some physical, biochemi
cal and hormonal parameters: a preliminary report
c.
C. P. Th. Schijf, M. G. Thomas, P. N. M. Demacker, W. H.
Doesburg and R. Rolland 585
x
FERTILITY AND STERILITY
64 Clinical comparison between a monophasic and a tri
phasic preparation
U. Lachnit-Fixson, S. Aydinlik and J. Lehnert 595
65 Comparative study of lipid metabolism and endocrine
function in women receiving levonorgestrel-and desoges
trel-containing oral contraceptives
U. J. Gaspard, M. A. Romus and D. Gillain 605
Section 3: Trends in Oral Contraception
66 Serum glycosylated proteins as a measure of carbohydrate
metabolism in users of oral contraceptives
H. J. Kloosterboer, G. J. Bruining, P. Liukko, S. Nummi and
L. Lund 615
67 Androgenic, oestrogenic and antioestrogenic effects of
desogestrel and lynestrenol alone: effects on serum pro
teins, sex hormones and vaginal cytology
G. Cullberg and L.-A. Mattsson 623
68 Influence of a desogestrel/ethinyloestradiol combination
pill on sex hormone binding globulin and plasma andro
gens
E. Keller, A. Jasper, M. Zwirner, H. Unterberg, T. Schu-
macher and A. E. Schindler 631
69 Comparative haematological effects of new ethinyl
oestradiol-progestogen combinations
M. H. Briggs 637
70 Oestroprogestogens and serum lipoproteins
F. R. Heller and C. Harvengt 643
71 Cycle control and modern contraception: some relevant
aspects
M. J. Weijers 653
72 Studies with desogestrel for fertility regulation
J. R. Newton 663
xi
