Table Of ContentEuropean  Journal  of 
Clinical  Investigation 
The Journal of The European Society for Clinical Investigation 
Editors-in-Chief  A. M. McGregor, J. Moxham, A. L. W. F. Eddleston 
Volume  26, 1996 
Oxford London Edinburgh Boston Melbourne Paris Berlin Vienna
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Contents  of Volume  26 
Number 1, January 1996  Sex differences in initial clearance of palmitate 
by human hepatocytes:  S. M. Pond, 
Review: The Jak-STAT pathway: specific 
R. A. Gordon and L. Bass 
signal transduction from the cell membrane to 
the nucleus: M. H. Heim  High tissue factor concentration in the omentum, 
a possible cause of its hemostatic properties: 
Apolipoprotein E2 (Arg-136 — Cys), a variant 
A. Logmans, C. H. H. Schoenmakers, 
of apolipoprotein E associated with late-onset 
S. M. Haensel, I. Koolhaven, J. B. Trimbos, 
dominance of type III hyperlipoproteinaemia: 
M. van Lent and H. E. van Ingen 
G. Feussner, M. Albanese,  W. A. Mann, 
A. Valencia and H. Schuster  Rapid Communication:  Induction of 
glutathione-S-transferase-pi by short-chain 
Serial changes in serum vitamin K,, 
fatty acid in the intestinal cell line caco-2: 
triglyceride, cholesterol, osteocalcin and 
J. Stein, O. Schréder, M. Bonk, G. Oremek, 
25-hydroxyvitamin D, in patients after hip 
M.  Lorenz and W. F. Caspary 
replacement for fractured neck of femur or 
osteoarthritis:  N. B. Roberts, J. D. Holding,  Erratum 
H. P. J. Walsh, L. Klenerman,  T. Helliwell, 
D. King and M. Shearer  Instructions to authors 
Altered release of endothelin-1,2 and 
thromboxane B, from trophoblastic cells in  Number 2, February 1996 
pre-eclampsia:  M. Cervar, F. Kainer, C. J. P. 
Review: Triglyceride-rich lipoproteins in 
Jones and G. Desoye 
non-insulin-dependent diabetes mellitus: 
Decreased release of glutathione into the  post-prandial metabolism and relation to 
systemic circulation of patients with HIV  premature atherosclerosis: F. H. A. F. de Man, 
infection:  B. Helbling, J. von Overbeck and  M. Castro Cabezas, H. H. J. J. van Barlingen, 
B. H. Lauterburg  D. W. Erkelens and T. W. A. de Bruin 
Immunosuppressive effects of endotoxins and  Review: The assembly of lipoprotein Lp(a): 
bile acids in vivo in the rat: K. Aouad,  S. Frank, S. Durovic and G. M. Kostner 
Y. Calmus, B. Nordlinger, A. Myara, B. Weill 
and R. Poupon  Elevated cell-associated levels of interleukin 17 
and interleukin 6 in inflamed mucosa of 
Smoking further increases platelet activity in  inflammatory bowel disease:  E. Gréttrup- 
patients with mild hypertension: G. Gleerup  Wolfers, J. Moeller,  U. Karbach, 
and K. Winther  S. Miiller-Lissner and S. Endres 
Regulation of platelet-activating factor  Use of recombinant human erythropoietin in 
production in gastric epithelial cells: J. Sobhani,  combination with parenteral iron in the 
Y. Denizot, L. Moizo, J. P. Laigneau, A. Bardo,  treatment of postpartum anaemia: 
C. Laboisse, J. Benveniste and M. J. M. Lewin  C. Breymann, R. Zimmermann,  R. Huch and 
A. Huch 
Reduction in thyroid volume after radioiodine 
therapy of Graves’ hyperthyroidism: results of  Assay of human erythrocyte sodium- 
a prospective, randomized, multicentre study:  dependent lithium efflux: the importance of 
H. Peters, C. Fischer,  U. Bogner, C. Reiners  timing of blood sampling: G. J. Adebayo, 
and H. Schleusener  P. Gaffney, M. Sinnott and J. Feely 
Erythrocyte Nat-H* exchanger kinetics and  Defective interferon-gamma production by 
Na*-Li* countertransport activity in essential  T-lymphocytes from patients with acute 
hypertensive patients: P. Delva, C. Pastori,  brucellosis: M. Rodriguez-Zapata, I. Salmeron, 
M. Degan, G. Montesi, C. Lechi,  L. Manzano, O. J. Salmeron, A. Prieto and 
A. Steele and A. Lechi  M.  Alvarez-Mon 
Co-regulation of apo A-I, apo C-III and apo  Partial conservation of the sn-2 position of 
A-IV gene expression in human intestinal  dietary triglycerides in fasting plasma lipids 
biopsies: S. Metzger,  Y. Levy, R. Arnon and  in humans: P. L. Zock, J. Gerritsen and 
T. Chajek-Shaul  M. B. Katan
CONTENTS 
Objective determination of pH thresholds in  Measurement of post-absorptive glucose 
the analysis of 24h ambulatory oesophageal  kinetics in non-insulin-dependent diabetic 
pH monitoring: B. L. A. M. Weusten, J. M. M.  patients: methodological aspects:  V. Rigalleau, 
Roelofs, L. M. A. Akkermans, G. P. vanBerge-  M. Beylot, M. Laville, C. Guillot, G. Deleris, 
Henegouwen and A. J. P. M. Smout  J. Aubertin and H. Gin 
Cytokine profiles in bronchoalveolar lavage  Increased serum concentrations of the 
fluid and blood in HIV-seronegative patients  carboxy-terminal cross-linked telopeptide of 
with Pneumocystis carinii pneumonia:  R. M.  collagen type | in patients with Gram-negative 
Perenboom,  A. C. H. W. van Schijndel,  septicaemia: C. Wenisch,  W. Graninger, 
P. Beckers, R. Sauerwein,  H. W. van  E. Schénthal and H. Rumpold 
Hamersvelt, J. Festen, H. Gallati and J. W. M. 
Regression speed of cardiac myosin heavy- 
van der Meer 
chain isozyme V3 in loaded right or left 
Rapid Communication:  [n vitro  ventricle after relief of the load: S.-J. Imamura, 
inactivation of mammalian methionine  A. Takao and R. Matsuoka 
synthase by nitric oxide: A. Nicolaou, S. H. 
Plasma factor VII and its relation to adipose 
Kenyon, J. M. Gibbons,  T. Ast and W. A. 
tissue fatty acids and other atherogenic risk 
Gibbons 
factors in healthy men:  M. Cigolini, 
Rapid Communication: Erythrocyte  G. Targher, J. C. Seidell, R. Schiavon, 
membrane fluidity in adult polycystic kidney  M. Tonoli, M. Muggeo and G. De Sandre 
disease: difference between intact cells and 
Rapid Communication:  Growth hormone 
ghost membranes:  K. Vareesangthip,  T. H. 
potentiates the im vivo biological activities of 
Thomas,  P. Tong and R. Wilkinson 
endotoxin in the rat:  W. Liao, M. Rudling and 
B. Angelin 
Number 3, March  1996 
Number 4, April 1996 
Review: Molecular determinants of human 
immunodeficiency virus type I phenotype  Commentary: Steroid hormones and 
variability:  R. A. M. Fouchier and H.  adipose tissue: J. B. Prins, S. O’Rahilly and 
Schuitemaker  V. K.  K. Chatterjee 
Serum and urine markers of type I collagen  Identification of oestrogen receptors and 
metabolism in elderly women with high and  oestrogen receptor mRNA in human adipose 
low bone mineral density: S. Cheng,  tissue: S. B. Pedersen, P. S. Hansen, S. Lund, 
V. Kovanen,  E. Heikkinen and H. Suominen  P. H. Andersen, A. Odgaard and B. Richelsen 
Preserved vasodilator response to adenosine in  Erythropoietic protoporphyria: two populations 
insulin-dependent diabetes mellitus: G. A.  of reticulocytes, with and without proto- 
Rongen, E. Ginneken,  Th. Thien, J. A.  porphyrin: A. Brun, H. Steen and S. Sandberg 
Lutterman and P. Smits 
Effect of regular physical training on age- 
Influences of lipid and non-lipid nutritional  associated alteration of body composition in 
parameters on factor VII coagulant activity in  men:  F. F. Horber, S. A. Kohler, K. Lippuner 
normal subjects: the Nove Study: D. Girelli,  and P. Jaeger 
O. Olivieri, P. L. Arigliano, P. Guarini, A. Bassi 
Synergistic stimulatory effects of tumour 
and R. Corrocher 
necrosis factor a and interferon y on 
Complete congenital heart block is associated  replication of human immunodeficiency virus 
with increased autoantibody titers against  type 1 and on apoptosis of HIV-1-infected host 
calreticulin:  7. Orth, T. Dérner, K.-H. Meyer  cells: ¥. Han, K. Becker, H. J. Degen, 
zum Biischenfelde and W. -J. Mayet  H. Jablonowski and G. Strohmeyer 
Multiple abnormalities in the transfer of  Echo-Doppler left ventricular filling 
phospholipids from VLDL and LDL to HDL  abnormalities in patients with rheumatoid 
in non-insulin-dependent diabetes: M. Elchebly,  arthritis without clinically evident 
T. Pulcini, B. Porokhov, F. Berthezene and  cardiovascular disease: S. Corrao, L. Salli, 
G. Ponsin  S. Arnone, R. Scaglione, A. Pinto and G. Licata 
Elevated serum neopterin level: its relation to  Serum neurone-specific enolase as an indicator 
endotoxaemia and sepsis in patients with  of stroke volume: R. T. Cunningham, M. Watt, 
major burns:  Y.-M.  Yao, Y. Yu, Y. P. Wang,  J. Winder, S. McKinstry, J. T. Lawson, C. F. 
H.-M.  Tian and Z.-Y. Sheng  Johnston, S. A. Hawkins and K. D. Buchanan
CONTENTS 
The effect of folic acid on the homocysteine  Bone alkaline phosphatase measured with a 
metabolism in human umbilical vein  new immunoradiometric assay in patients with 
endothelial cells (HUVECs): E. F. Van Der  metabolic bone diseases: S. Gonnelli, 
Molen, L. P. W. J. Van den Heuvel, M. T. W.  C. Cepollaro, A. Montagnani, G. Monaci, 
B. Te Poele Pothoff, L. A. H. Monnens, T. K. A.  M. S. Campagna, M. B. Franci and C. Gennari 
B. Eskes and H. J. Blom 
Effect of cyproheptadine on episodic ACTH 
Differences in phospholipase A, activity  and cortisol secretion:  T. H. Schiirmeyer, 
between males and females and Asian Indians  G. Brademann and A. von zur Miihlen 
and Caucasians:  T. Kuslys, B. S. Vishwanath,  Kinetics of soluble TNF-receptors and soluble 
F. J. Frey and B. M. Frey 
adhesion molecules ICAM-1, E-selectin, and 
VCAM.-1  under systemic rhTNFa therapy: 
Hyperlipoprotein(a)aemia in nephrotic 
syndrome: J. Thiery, B. Ivandic, G. Bahlmann,  M.  W. J. Boehme, R. Waldherr, A. Kist, 
A. K. Walli and D. Seidel  S. Riedl, R. Wailter-Kirst, J. Kempeni and 
U. Raeth 
Quantitative and qualitative alterations of 
The antifibrinolytic effect of lipoprotein(a) in 
dystrophin are expressed in muscle cell cultures 
heterozygous subjects is modulated by the 
of Xp21 muscular dystrophy patients 
relative concentration of each of the 
(Duchenne and Becker type): T. Mongini, 
apolipoprotein(a) isoforms and their affinity 
C. Doriguzzi, L. Palmucci and L. Chiado Piat 
for fibrin : L. Hervio, A. Girard-Globa, 
Arginine, lysine and ornithine as vasodilators  V. Durlach and E. Anglés-Cano 
in the forearm of man:  P. Rhodes, C. S. Barr 
The isoform-specific expression of the tri- 
and A. D. Struthers  iodothyronine receptor in osteoblasts and 
Acute hyperinsulinaemia decreases cholesterol  osteoclasts:  T. J. Allain, P. M. Yen, 
A. M. Flanagan and A. M. McGregor 
synthesis less in subjects with non-insulin- 
dependent diabetes mellitus than in non- 
diabetic subjects: R. P. Naoumova, 
M. H. Cummings, G. F. Watts, N. B. Rendell, 
Number 6, June 1996 
G. W. Taylor, P.H.SonksenandG. R. Thompson 
Review: Human serum amyloid A (SAA) 
Erratum 
protein: a prominent acute-phase reactant for 
clinical practice: E. Malle and F. C. de Beer 
Number 5, May 1996  Review: Vitamin D deficiency and 
osteoporosis: the role of vitamin D deficiency 
Review: Pathogenesis of cholesterol  and treatment with vitamin D and analogues 
gallstones: a parsimonious hypothesis:  in the prevention of osteoporosis-related 
M. D. Apstein and M. C. Carey  fractures:  P. Lips 
Review: Role of catecholamines in platelet  Nerve conduction velocity in human limbs 
function: pathophysiological and clinical  with late sequelae after local cold injury: A. 
significance: G. Anfossi and M.  Trovati  Arvesen, J. Wilson and L. Rosén 
First-pass uptake of methotrexate after  Minimal myocardial lesions caused by 
intra-arterial bolus injection in human  endomyocardial biopsy can be detected by a 
head and neck cancers:  B. Bléchi-Daum,  commercially available cardiac troponin-T 
R. Mader,  W. Millesi, S. Lang, H. Rainer,  enzyme-linked immunosorbent assay: K. Lang, 
R. Eglmeier, M. Miiller, G. Zanaschka and  H. H. Sigusch, A. Borner, M. Hoffmann, 
H. G. Eichler  H. Kiihnert,  U. Leder and S. Miiller 
Elevated plasma adrenomedullin level in 
Inhibited neutrophil functions in patients 
hyperthyroidism:  M. Taniyama, K. Kitamura, 
treated with nifedipine but not with verapamil 
Y. Ban, T. Eto and T. Katagiri 
or diltiazem: R. Levy, O. Nagauker-Shriker and 
F. Schlaeffer  Computerized evaluation of skin stiffening in 
scleroderma:  N. Nikkels-Tassoudji, F. Henry, 
Normalization of peripheral thyroid hormone 
C. Piérard-Franchimont and G. E. Piérard 
metabolism induced by successful chronic 
amiodarone treatment in patients with  Effects of group-A streptolysin O on neonatal 
ventricular arrhythmias: G. Jervasi, A. Clerico,  and adult red blood cell deformability and 
S. Berti, A. Pilo, A. Biagini, R. Bianchi and  haemolysis: J. M. B. Péschl, P. Ruef, 
L. Donato  M. Schnauffer and O. Linderkamp
CONTENTS 
Immunochemical and biomolecular studies of  Review: The pathogenesis of vascular 
circulating immune complexes isolated from  complications of diabetes mellitus: one voice 
patients with acute and chronic hepatitis C  or many? : C. D. A. Stehouwer and 
virus infection:  D. Sansonno, A. R. Iacobelli,  N. C. Schaper 
V. Cornacchiulo,  G. Lauletta, M. A. Distasi, 
Prostacyclin (PGI,): a potential mediator of c- 
P. Gatti and F. Dammacco 
fos expression induced by hydrostatic 
Rate of development of mutation at codon 215  pressure in osteoblastic cells : H. Glantschnig, 
of HIV-1  reverse transcriptase and its  F. Varga, M. Rumpler and K. Klaushofer 
predictive factors at the time of initiation of  Cyclosporine induces high bone turnover and 
zidovudine therapy: M. Leal, C. Rey,  may contribute to bone loss after heart 
Y. Torres, F. Relimpio, R. Pino, E. Lissen,  transplantation:  D. Thiébaud, M. A. Krieg, 
A. Sanchez-Quijano and F. Luque  D. Gillard-Berguer, A. F. Jacquet, J. J. Goy and 
P. Burckhardt 
The effect of the menstrual cycle on exhaled 
nitric oxide and urinary nitrate concentration:  Renovascular hypertension and insulin 
N. H. Morris, S. R. Sooranna,  P. J. Steer and  sensitivity: A. Natali, A. Quifiones Galvan, 
J. B. Warren  F. Arzilli, S. Taddei, N. Pecori, S. Frascerra, 
A. Salvetti and E. Ferrannini 
Absence of cholesteryl ester transfer protein- 
mediated cholesteryl ester mass transfer from  Association between eating behaviour and 
high-density lipoprotein to low-density  current glycaemic control, body mass or 
lipoprotein particles is a major feature of  autonomic nervous function in long-term type 
combined hyperlipidaemia:  M. Guerin,  I and type II diabetic patients : R. H. Straub, 
E. Bruckert, P. J. Dolphin and M. J. Chapman  L. Lamparter-Lang,  K. -D. Palitzsch and 
J. Schélmerich 
Quantitative analysis of HCV RNA and 
genotype in patients with chronic hepatitis C  Activation of endothelial cells during insulin- 
accompanied by oral lichen planus:  Y. Nagao,  dependent diabetes mellitus: a biochemical and 
M. Sata, K. Itoh, K. Tanikawa and T. Kameyama  morphological study: N. Cester, R. A. Rabini, 
E. Salvolini, R. Staffolani, A. Curatola, 
Induction of heat shock protein 70 genes in  A. Pugnaloni, M. A. Brunelli, G. Biagini and 
human lymphocytes during fever therapy:  L. Mazzanti 
R. Dressel, L. Heine, L. Elsner, G. Geginat, 
Intestinal phase of human antro-pyloro- 
O. Gefeller, K. F. Kélmel and E. Griinther 
duodenal motility: cholinergic and CCK- 
Human simple renal cyst fluid contains a cyst  mediated regulation: M. Katschinski, 
formation-promoting activity for Madin-  J. Schirra, C. Beglinger, S. Langbein, 
Darby canine kidney cells cultured in collagen  U. Wank, M. D’Amato and R. Araold 
gel: M. Taide, S. Kanda,  T. Igawa, J. Eguchi, 
Renal and hormonal actions of atrial 
H. Kanetake and Y. Saito 
natriuretic peptide during angiotensin II or 
Epitope mapping of the Ro/SSA60KD  noradrenaline infusion in man : H. Eiskjer, 
autoantigen reveals disease-specific antibody-  C. B. Nielsen, S. S. Sorensen and 
binding profiles: J. G. Routsias, A. G. Tzioufas,  E. B. Pedersen 
M. Sakarellos-Daitsiotis,  C. Sakarellos and  Detection of gram-negative bacteraemia in 
H. M. Moutsopoulos  early sepsis by a quantitative chromogenic and 
kinetic endotoxin assay: D. Massignon, 
Rapid Communication: Endothelium 
A. Lepape, G. Debize, M. F. Remillieux, 
activation related increase in soluble 
V. De Pasquale,  V. Banssillon and P. Ceur 
intercellular adhesion molecule-1  in human 
schistosomiasis.  Lack of correlation with  Effects of bile salt hydrophobicity on 
serology: H. Lejoly-Boisseau, A. D. Blann,  crystallization of cholesterol in model bile: 
M. Seigneur, J. Tribouley-Duret, J. Tribouley  K. J. van Erpecum, P. Portincasa, M. Gadellaa, 
and M. R. Boisseau  B. J. M. van de Heijning, G. P. van Berge 
Henegouwen and W. Renooij 
Rapid Communication: Tumour necrosis 
Number 7, July 1996  factor alpha stimulates gastrin release from 
canine and human antral G cells: possible 
Review: Growth hormone, insulin-like  mechanism of the Helicobacter pylori—gastrin 
growth factors and bone remodelling:  link : J. L. P. Beales, L. Post, J. Calam, 
E. F. Eriksen, M. Kassem and B. Langdahl  T. Yamada and J. Delvalle
CONTENTS 
Number 8, August 1996  Elevation of plasminogen activator inhibitor 1 
in borderline hypertension is linked to 
Review: RET receptor tyrosine kinase gene  concomitant metabolic disturbances: C. Lemne 
mutations: molecular biological,  and U. de Faire 
physiological and clinical aspects: J. W. M. 
Hoppener and C. J. M. Lips  Effects of the sulphydryldonor N-acetyl-l- 
cysteine on nerve conduction, perfusion 
Review: Antihypertensive drugs and  maturation and regeneration following freeze 
cerebral circulation:  S. Strandgaard and  damage in diabetic rats: A. Love, M. A. Cotter 
O. B. Paulson  and N. E. Cameron 
Lipoprotein lipase gene mutations DON and  Involvement of the l-arginine—nitric oxide 
N291S in four pedigrees with familial  pathway in hyperglycaemia-induced coronary 
combined hyperlipidaemia:  T. W. A. de Bruin,  artery dysfunction of isolated guinea pig 
F. Mailly, H. H. J. J. van Barlingen, R. Fisher,  hearts:  T. C. Wascher,  M. Bachernegg, 
M. Castro Cabezas, P. Talmud,  A. Kickenweiz, G. Stark, U. Stark, H. Toplak 
G. M. Dallinga-Thie and S. E. Humphries  and W. F. Graier 
Islet cell autoimmunity and progression to  Erratum 
insulin-dependent diabetes mellitus in 
genetically high- and low-risk siblings of  Number 9, September 1996 
diabetic children: J. Karjalainen, P. Vahasalo, 
M. Knip, E. Tuomilehto-Wolf, E. Virtala,  Review:  Bile acid transport systems as 
H. K. Akerblom and The Childhood Diabetes in  pharmaceutical targets:  W. Kramer and 
Finland (DiMe)  Study Group  G. Wess 
Insulin resistance shows selective metabolic  Review: Apolipoprotein function in health 
and hormonal targets in the elderly:  and disease: insights from natural mutations: 
G. Pagano, S. Marena, L. Scaglione, P. Bodoni,  G. Franceschini 
G. Montegrosso, A. Bruno, M. Cassader,  Red blood cell aggregability is increased by 
G. Bonetti and P. Cavallo Perin  aspirin and flow stress, whereas dipyridamole 
induces cell shape alterations:  measurements 
Effects of glycerol trinitrate on the pyloric 
by digital image analysis : J. Bozzo, 
motor response to intraduodenal  triglyceride 
M. R. Hernandez,  A. del Giorgio and 
infusion in humans:  W. M. Sun, S. Doran, 
A. Ordinas 
Th. Lingenfelser, G. S. Hebbard, J. E. Morley, 
J. Dent and M. Horowitz  Utilization of myristic and palmitic acid in 
humans fed different dietary fats: 
Peripancreatic lymphoadenopathy and 
D. E. MacDougall,  P. J. H. Jones, J. Vogt, 
extrahepatic immunological manifestations in 
P. T. Phang and D. D. Kitts 
chronic hepatitis C: S. Neri, C. M. Bruno, 
G. D’Angelo and S. Russo  Effects of low- and conventional-dose 
transcutaneous  HRT over 2 years on bone 
Decrease in lipoprotein(a) after renal  metabolism in younger and older 
transplantation is related to the glucocorticoid  postmenopausal women:  C. A. Sharp, 
dose: N. von Ahsen, M. Helmhold, T. Eisenhauer,  S. F. Evans, L. Risteli, J. Risteli, M.  Worsfold 
V. W. Armstrong and M. Oellerich  and M. W. J. Davie 
Divergent effects of propranolol and nadolol in  Direct vasodilator effects of physiological 
isolated mesenteric arteries from normal and  hyperinsulinaemia in human skeletal muscle: 
portal hypertensive rats:  R. E. Stauber,  C. J. J. Tack, A. E. P. Schefman, J. L. Willems, 
A. Heinemann, M. Trauner and G. J. Krejs  T. Thien, J. A. Lutterman and P. Smits 
New evidence that serum (-microglobulin  A simple, rapid immunometric assay for 
behaves as a biological marker of bone  determination of functional and growth 
remodelling in women:  E. Ripoli, M. Revilla,  hormone-occupied growth hormone-binding 
E. R. Hernandez, I. Arribas, L. F. Villa, H. Rico  protein in human serum: S. Fisker, J. Frystyk, 
[132/95]  L. Skriver, E. Vestbo, K. K. Y. Ho and 
H. Orskov 
Longitudinal analysis of soluble intercellular 
adhesion molecule  | in retinal vasculitis  Complexes between proteinase 3, a;- 
patients: H. E. Palmer, A. G. Zaman,  antitrypsin and proteinase 3 anti-neutrophil 
B. A. Ellis, M. R. Stanford, E. M. Graham and  cytoplasm autoantibodies:  a comparison 
G. R. Wallace  between a,-antitrypsin PiZ allele carriers and
viii  CONTENTS 
non-carriers with Wegener’s granulomatosis:  Expression of nitric oxide synthase in 
B. Baslund,  W. Szpirt, S. Eriksson, A.-N.  ulcerative colitis: A. J. Godkin, A. J. de Belder, 
Elzouki, A. Wiik, J. Wieslander and J. Petersen  L. Villa, A. Wong, J. E. Beesley, S. P. Kane and 
J. F. Martin 
Vitamin D receptor genotypes are related to 
bone size and bone density in men: A. G. Need,  OKT3-induced nephrotoxicity is associated 
M. Horowitz, A. Stiliano, F. Scopacasa,  with release of group II secretory 
H. A. Morris and B. E. Chatterton  phospholipase A>: P. C. Wever, R. W. Roest, 
A. M. Wolbink-Kamp, G. J. Wolbink, J. J. 
Synthesis and release of phosphatidylcholine 
Weening, C. E. Hack and R. J. M. Ten Berge 
by isolated porcine gastric mucous cells in 
primary culture:  W. Bernhard, H. Schulte,  Lack of effect of desmopressin on ACTH and 
M. Piller and K.-F. Sewing  cortisol responses to ovine corticotropin- 
releasing hormone in anorexia nervosa: 
Butyrate enhances major histocompatibility 
L. Foppiani, P. Sessarego, S. Valenti, M. R. 
complex class I, HLA-DR and ICAM-1 
Falivene, C. M. Cuttica and M.  Giusti Disem 
antigen expression on differentiated human 
intestinal epithelial cells: S. Siavoshian,  Effects of N-acetylcysteine on bacterial 
H. M. Blottiére, N. Bentouimou,  C. Cherbut  clearance:  T. Koch, S. Heller, S. Hei(ler, 
and J. P. Galmiche  I. Breil, H. G. Schiefer, K. van Ackern and 
H. Neuhof 
Adrenalitis and the adrenocortical response of 
resistant and susceptible mice to acute murine  Defective biliary copper excretion in Wilson’s 
cytomegalovirus infection:  P. Price,  disease: the role of caeruloplasmin:  W. Davis, 
S. D. Olver, M. Silich,  T. Z. Nador,  G. F. E. Chowrimootoo and C. A. Seymour 
S. Yerkovich and S. G. Wilson  Carrier detection by microsatellite haplotyping 
Elevated serum transforming growth factor (1  in 10 properdin type 1-deficient families: 
level in primary lung cancer patients with  C. A. P. Fijen, R. van den Bogaard, M. R. Daha, 
finger clubbing:  Y. Hirakata and S. Kitamura  J. Dankert, M. Mannens and E. J. Kuijper 
The value of serial determination of MEGX 
Rapid Communication: Vasodilator  and hyaluronic acid early after orthotopic liver 
responses to nitric oxide are enhanced in  transplaniation: E. Schiitz, M. Luy-Kaltefleiter, 
mesenteric arteries of portal hypertensive  M. Kaltefleiter, M. Burdelski, B. Ringe, V. W. 
rats:  A. Heinemann and R. E. Stauber  Armstrong and M. Oellerich 
Red blood cell ghosts are affected by 
adrenoleucodystrophy:  G. Arienti, E. Carlini, 
Number 10, October 1996 
S. Laureti, P. Brunetti and F. Santeusanio 
Review:  Islet cell autoantigens in type I  HIV-1  viraemia changes in patients with and 
diabetes:  M. R. Christie  without syncytium-inducing phenotype treated 
Plasma noradrenaline and ageing: effects of  with nucleoside analogues: a case—control 
smoking habits:  E. W. Jensen, K. Espersen,  study: M. Leal,  Y. Torres, F. J. Medrano, 
I.-L. Kanstrup and N. J. Christensen  C. Rey, A. Caruz, A. Sanchez-Quijano and 
E. Lissen 
Effect of polymorphism in the insulin gene 
region on IDDM susceptibility and insulin  Effect of hypercholesterolaemia on platelet 
secretion:  M. Halminen,  R. Veijola,  growth factors: J. Garcia-Bolao, J. Merino, 
H. Reijonen, J. Ilonen, H. K. Akerblom,  A. Martinez, A. Grau, E. Alegria and 
M. Knip and the Childhood Diabetes in Finland  D. Martinez-Caro 
(DiMe)  Study Group  Rapid Communication: Elevated 
Hyperhomocysteinaemia — a common finding  interleukin-1/( in the circulation of patients 
in a psychogeriatric population:  K. Nilsson,  with essential hypertension before any drug 
L. Gustafson,  R. Faldt, A. Andersson,  therapy: a pilot study: G. N. Dalekos, 
L. Brattstrém, A. Lindgren, B. Israelsson and  M.S. Elisaf, N. Papagalanis, C. Tzallas and 
B. Hultberg  K. Siamopoulos 
Rapid Communication: Acute insulin» 
lloprost effects on phagocytes in patients 
suffering from ischaemic diseases: in vivo  administration does not affect plasma leptin 
evidence for down-regulation of aM,  levels in lean or obese subjects: E. Muscelli, 
S. Camastra, A. Masoni, S. Baldi, A. M. Sironi, 
integrin: A. Mazzone, I Mazzucchelli, 
G. Fossati, D. Gritti, S. Girola, C. Canale,  A. Natali and E. Ferrannini 
C. Cusa and G. Ricevuti  Letter to the Editor
CONTENTS 
Number 11, November 1996  Cytokine profile in chronic cardiac failure: 
I. C. Steele, A.-M. Nugent, S. Maguire, 
Ultrasonic parameters of bone in young 
M. Hoper, G. Campbell, M. I. Halliday and 
normals: effect of age and sex: S. Minisola,  D. P. Nicholls 
C. Tirafili, R. Rosso, G. Costa and G. Mazzuoli 
Human and porcine smooth muscle cells share 
Dexamethasone and cyclosporin A 
similar proliferation dependence on the 
modulation of cytokine expression and specific 
mevalonate pathway: implication for in vivo 
antibody synthesis in an allergic 
interventions in the porcine model: 
bronchopulmonary aspergillosis murine 
J. Martinez-Gonzdlez and Lina Badimon 
model: J. M.  Wang, H. W. Chu, M. Bossé, 
J. St-Pierre,  M. Boutet and M. Laviolette  Prospective cross-over comparisons of three 
low-density lipoprotein (LDL)-apheresis 
Multifactorial  treatment of hypertensive men 
methods in patients with familial 
at high cardiovascular risk and low-density 
hypercholesterolaemia:  D. Schaumann, 
lipoprotein cholesterol affinity to human 
M.  Welch-Wichary,  A. Voss, H. Schmidt and 
arterial proteoglycans:  B. Fagerberg, 
C. J. Olbricht 
O. Wiklund, S. Agewall, G. Camejo and 
R. J. Wikstrand  Referees for 1995 
Effects of vasopressin on human renal arteries: 
P. Medina, J. M. Vila, M. C. Martinez,  Number 12, December 1996 
M. Aldasoro,  P. Chuan and S. Lluch 
Review: Physiology and pathophysiology of 
The effects of hyperinsulinaemia on  aquaporins: S. M. Mulders, A. F. van Leiburg, 
myocardial mass, blood pressure regulation  L. A. H. Monnens,  N. V. A. M. Knoers, 
and central haemodynamics in rats:  P. M. T. Deen and C. H. van Os 
A. Holmdng, N. Yoshida, E. Jennische, 
Identification of steroid receptors in human 
A. Waldenstrém and P. Bjérntorp 
adipose tissue: S. B. Pedersen, S. Fuglsig, 
Kinetics of primary bile acids in patients after  P. Sjogren and B. Richelsen 
orthotopic liver transplantation:  P. Sauer, 
Biosynthesis of prostacyclin and thromboxane 
G. Rudolph, R. Endele, M. Senn, L. Theilmann, 
A, during chronic hypoxaemia in children with 
G. Otto,  W. Stremmel and A. Stiehl 
cyanotic congential heart disease: A. Leonhardt, 
A method for the isolation and preparation of  J. Magsaam, M. Goldner, P. G. Kiihl and 
surfactant from tracheobronchial aspirates in  H. W. Seyberth 
infants and children for quantitative and 
Effect of hormone replacement therapy on the 
pulsating bubble analysis: K. Raymondos, 
susceptibility of low-density lipoprotein to 
I. Martin-Carrera,  W. Bernhard,  C. Poets and 
oxidation among postmenopausal 
H. von der Hardt 
hypercholesterolaemic women: M. S. Nenseter, 
Human corticotropin-releasing hormone and  V. Volden,  T. Berg, C. A. Drevon, L. Ose and 
thyrotropin-releasing hormone modulate the  S. Tonstad 
hypercapnic ventilatory response in humans: 
Phyllanthus amarus down-regulates hepatitis 
R. Schulz, M. Nink, G. S. Werner, S. Andreas, 
B virus mRNA transcription and replication: 
H. Kreuzer, J. Beyer and H. Lehnert 
C. -D. Lee, M. Ott, S. P. Thyagarajan, D. A. 
Flow cytometric analysis of platelet activation  Shafritz, R. D. Burke and S. Gupta 
markers CD62P and CD63 in patients with 
Diadenosine polyphosphates induce 
coronary artery disease:  T. Murakami, 
transplasma membrane calcium influx in 
Y. Komiyama,  M. Masuda, H. Kido, 
cultured glomerular mesangial cells: M. Tepel, 
S. Nomura, S. Fukuhara, M. Karakawa, 
S. Heidenreich,  H. Schliiter, A. Beinlich, 
T. Iwasaka and H. Takahashi 
J. R. Nofer and M. Walter 
Influence of insulin on cholesterol removal from 
macrophages and cholesterol ester uptake by  Effects of isolated limb perfusion with tumour 
HepG2 cells: J. Wybranska, E. Baczynska,  necrosis factor-alpha on the function of 
monocytes and T lymphocytes in patients with 
U. Ciatowicz, A. Polus and A. Dembiriska-Kiec 
cancer:  T. C. Stam, M. Jongen-Lavrencic, 
Characterization of a soluble form of neutral 
A. M. M. Eggermont and A. J. G. Swaak 
endopeptidase-24.11  (EC 3.4.24.11) in human 
serum: enhancement of its activity in serum of  Molecular analysis of the T-cell receptor 
underground miners exposed to coal dust  b-chain repertoire in early rheumatoid 
particles: J.-M. Soleilhac, C. Lafuma,  arthritis: heterogeneous TCRBV gene usage 
J.-M. Porcher, G. Auburtin and B. P. Roques  1011  with shared amino acid profiles in CDR3
CONTENTS 
regions of T lymphocytes in multiple synovial  and coronary heart disease in a Japanese 
tissue needle biopsies from the same joint:  population: H. Bai, K. Saku, R. Liu,  Y. Oribe, 
L. Struyk, G. E. Hawes, H. M. M. Mikkers,  K. Yamamoto and K. Arakawa 
P.-P. Tak, F.C. Breedveldand P.J. vanden Elsen 
Different effects of continuous 
Helicobacter pylori and proteolytic activity:  oestrogenprogestin and transdermal oestrogen 
M. Nilius, M. Pugliese and P. Malfertheiner  with cyclic progestin regimens on 
low-density lipoprotein subclasses:  M. Tilly- 
To determine the effects of ultraviolet light,  Keisei, M. Lappi, J. Puolakka, H. Luotola, 
natural light and ionizing radiation on  T. Pyérala and M.-R.  Taskinen 
pyridinium cross-links in bone and urine using 
Screening and characterization of specific anti- 
high-performance liquid chromatography: 
lipopolysaccharide antibodies in Belgian blood 
A. Colwell,  A. Hamer, A. Blumsohn and 
donors by enzyme-linked immunosorbent 
R. Eastell 
assays: M. Nys, R. Laub, P. Damas, D. Sondag, 
Polymorphism of the apolipoprotein A-IV  T. Goethals, D. Jamaer, L. Joassin and 
gene and its significance in lipid metabolism  M. Lamy