Table Of ContentBrian E. Lacy · John K. DiBaise
Mark Pimentel · Alexander C. Ford
Editors
Essential Medical
Disorders of the Stomach
and Small Intestine
A Clinical Casebook
123
Essential Medical Disorders
of the Stomach and Small
Intestine
Brian E. Lacy PhD, MD
John K. DiBaise MD, FRCPC
Mark Pimentel MD, FRCP(C)
Alexander C. Ford MBChB,
MD, FRCP
Editors
Essential Medical
Disorders of the
Stomach and Small
Intestine
A Clinical Casebook
Editors
Brian E. Lacy John K. DiBaise
Mayo Clinic Mayo Clinic
Jacksonville, FL Scottsdale, AZ
USA USA
Mark Pimentel Alexander C. Ford
Cedars-Sinai Medical Center Leeds Teaching Hospitals
Los Angeles, CA NHS Trust
USA Leeds Gastroenterology Institute
Leeds
UK
ISBN 978-3-030-01116-1 ISBN 978-3-030-01117-8 (eBook)
https://doi.org/10.1007/978-3-030-01117-8
Library of Congress Control Number: 2018964576
© Springer Nature Switzerland AG 2019
This work is subject to copyright. All rights are reserved by the Publisher, whether
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The publisher, the authors, and the editors are safe to assume that the advice and
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The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Finally, we would all like to thank our families for
their unwavering support during this project.
Preface
Medical disorders of the stomach and small intestine are
quite common in the general population. Community-based
surveys consistently demonstrate that up to 20% of the
Western population suffers from symptoms of dyspepsia,
while 10% report symptoms of recurrent nausea and vomit-
ing, and more than 30% suffer from chronic symptoms of gas
and bloating. These symptoms are, unfortunately, persistent
for the majority of patients who, after failing dietary modifi-
cations and over-the-counter agents, turn to their primary
care providers for assistance and advice.
Despite the high prevalence of these disorders, a concise,
up-to-date, and easy-to-use reference source describing these
essential medical conditions of the stomach and small intes-
tine is not available. This book is designed to fill that educa-
tional gap. Using a case-based approach, a panel of
international experts has reviewed the 21 most common and
vital medical disorders of the stomach and small intestine.
The book is divided into five parts: nausea and vomiting,
dyspepsia and other disorders of neuromuscular function,
chronic abdominal pain, demystifying the challenging postop-
erative patient, and small bowel disorders. Each of the five
parts has been edited by experts in the field. Within each part,
chapters begin with a typical case study illustrating a specific
condition along with a list of learning objectives. The epide-
miology and pathophysiology of each condition are then
summarized, followed by a concise review of the diagnosis
vii
viii Preface
and treatment. Chapters will conclude with a follow-up of the
case study, after testing has been performed and treatment
initiated, and a list of key “clinical pearls” to highlight the
most important teaching points. Each chapter also contains a
series of test questions designed to emphasize important
clinical care issues surrounding each case. Answers to the
questions are provided at the end of the book, so that the
reader can track their knowledge about each disorder.
We would like to dedicate this book to two groups of
people. First, to our co-authors, who willingly, enthusiastically,
and cheerfully found time in their very busy lives to write a
state-of-the-art chapter on one of their specialties in gastro-
enterology. Your tireless efforts in support of this educational
endeavor are truly appreciated. Second, on behalf of all of the
editors and authors, this book is dedicated to our patients.
Thank you for letting us work with you and learn from you.
We hope that the information in this book will provide help-
ful educational information to health-care providers, so that
they will be able to provide exceptional care to their patients.
Lastly, writing and editing a book requires the combined
efforts of many people who work behind the scenes, often
without credit. We would like to thank our Developmental
Editor, Lorraine Coffey, for all of her hard work helping to
coordinate this project. We would also like to thank Andy
Kwan at Springer who was instrumental in bringing this proj-
ect to fruition. Finally, we would all like to thank our families
for their unwavering support during this project.
Jacksonville, FL, USA Brian E. Lacy, PhD, MD
Scottsdale, AZ, USA John K. DiBaise, MD, FRCPC
Los Angeles, CA, USA Mark Pimentel, MD, FRCP(C)
Leeds, UK Alexander C. Ford, MBChB,
MD, FRCP
Contents
Part I N ausea and Vomiting
1 A pproach to Nausea and Vomiting . . . . . . . . . . . . . . . . . 3
Zubair Malik and Henry P. Parkman
2 Gastroparesis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
Priya Vijayvargiya and Michael Camilleri
3 N ausea and Vomiting of Pregnancy
and Postoperative Nausea and Vomiting . . . . . . . . . . . . 51
Ted Walker and Gregory S. Sayuk
4 C yclic Vomiting Syndrome and Cannabinoid
Hyperemesis Syndrome . . . . . . . . . . . . . . . . . . . . . . . . . . 75
Michael J. Kingsley and David J. Levinthal
5 Chronic Intestinal Pseudo-Obstruction . . . . . . . . . . . . . 95
Sobia N. Laique and Scott L. Gabbard
Part II D yspepsia and Other Disorders
of Neuromuscular Function
6 A Diagnostic Approach to Dyspepsia . . . . . . . . . . . . . .125
Kimberly Harer and William L. Hasler
7 Helicobacter pylori and Related Diseases . . . . . . . . . .141
Muhammad Ali Khan and Colin W. Howden
8 Functional Dyspepsia . . . . . . . . . . . . . . . . . . . . . . . . . . . .155
Nicholas J. Talley and Dane R. Cook
ix
x Contents
9 Rumination Syndrome . . . . . . . . . . . . . . . . . . . . . . . . . . .173
Neelima Bonthi, Magnus Halland,
and David A. Katzka
10 Gas-Bloat Syndrome . . . . . . . . . . . . . . . . . . . . . . . . . . . .187
Carolina Malagelada and Juan R. Malagelada
Part III Chronic Abdominal Pain:
Common and Uncommon Causes
11 A Diagnostic Approach to Chronic
Abdominal Pain . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .209
Amrit K. Kamboj and Amy S. Oxentenko
12 Vascular Disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .233
David A. Tendler
13 C entrally Mediated Abdominal Pain Syndrome . . . . . .253
Imran Aziz, Hans Törnblom,
and Magnus Simrén
14 Postcholecystectomy Pain . . . . . . . . . . . . . . . . . . . . . . . .267
Enrico Stefano Corazziari and Nadia Pallotta
Part IV D emystifying the Challenging
Post-operative Patient
15 C ommon Upper Gastrointestinal Operations . . . . . . 285
Steven P. Bowers
16 C omplications of Gastrointestinal Surgery . . . . . . . . 321
Amar Mandalia and Allison R. Schulman
Part V Small Bowel Disorders
17 C eliac Disease and Non-c eliac Gluten Sensitivity . . . .353
Amanda K. Cartee and Joseph A. Murray
18 N on-celiac Small Bowel Enteropathies . . . . . . . . . . . . .375
Isabel A. Hujoel and Alberto Rubio-Tapia
Contents xi
19 Protein-Losing Enteropathy . . . . . . . . . . . . . . . . . . . . . .401
Brooke Corning and Andrew P. Copland
20 S mall Intestinal Bacterial Overgrowth . . . . . . . . . . . . . .417
Eamonn M. M. Quigley
21 Food Allergies, Food Intolerances,
and Carbohydrate Malabsorption . . . . . . . . . . . . . . . . . .437
John Leung, Apaar Dadlani,
and Sheila Eileen Crowe
Appendix: Answers to Self- Test Questions . . . . . . . . . . . . .459
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .487
