Table Of Content132 Anaesthesiologie und Intensivmedizin
Anaesthesiology
and Intensive Care Medicine
Herausgeber:
H. Bergmann . Linz (Schriftleiter)
J.B. Bruckner . Berlin R. Frey . Mainz
W.P. Henschel . Bremen P. Kern . St. Gallen
O. Mayrhofer . Wien K. Peter . Miinchen
Endocrinology
in Anaesthesia
and Surgery
Edited by
H. Stoeckel and T. Oyama
with the Co-operation of G. Hack
With 101 Figures
Springer-Verlag
Berlin Heidelberg New York 1980
Prof. Dr. Horst Stoeckel
Institut fUr Anaesthesiologie
der Universitat Bonn
Sigmund-Freud-StraBe 25
D-5300 Bonn-Venusberg, FRG
Prof. Dr. Tsutomu Oyama
Dept. of Anaesthesiology
University of Hirosaki
Japan
Co-operator:
Doz. Dr. Guido Hack
Institut fUr Anasthesiologie
der Universitat Bonn
Sigmund-Freud-StraBe 25
D-5300 Bonn-Venusberg, FRG
ISBN-13: 978-3-540-10211-3 e-ISBN-13: 978-3-642-67745-8
001: 10.1007/978-3-642-67745-8
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© by Springer-Verlag Berlin Heidelberg 1980.
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even if the former are not especially identified, is not be taken as a sign
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Typesetting: Schreibsatz Service Weihrauch, Wiirzburg
2127/3321-543210
Preface
The development of accurate hormonal assays in recent years
has evoked much interest in the area of anaesthesia and surgery.
In an effort to allow an exchange of ideas and new information
in this area, the First International Symposium on Endocrinology
in Anaesthesia and Surgery was held in Bonn during September
1978. The contents of this book represent much of the information
presented by the leading authorities in this field. The presentations
were grouped in three areas: 1. Basic problems of endocrinology
in anaesthesia and surgery; 2. The response of the endocrine system
to anaesthesia and surgery; 3. Hormone and anaesthetic management
of endocrine disease. As with any multi-authored text, there is
both repetition and diversity but hopefully the reader will be able
to obtain much of the useful information.
As Editors, we wish to express our deep appreciation to Profes
sor R. Frey and Springer-Verlag for including this book in the
series on "Anaesthesiology and Intensive Care Medicine".
H. Stoeckel
T. Oyama
Table of Contents
I. Basic Problems of Endocrinology in Anaesthesia and Surgery
H. Breuer
Basic Principles Regulating the Endocrine System . . . . . . . .. 3
G. Wesemann and E. Grote
Pathophysiology of Intra-and Postoperative Stress .. . . . . .. 10
M. Trede
Surgical Treatment of Endocrine Disorders .. . . . . . . . . . .. 24
T. Oyama
Influence of Anaesthesia on the Endocrine System ... . . . .. 39
L. Nocke-Finck
Radioimmunological Determination of Hormones.
Applicability and Evaluation in Severely III Patients ....... 52
L. Siekmann
Isotope Dilution - Mass Spectrometry. A Definitive Method
for the Determination of Hormones . . . . . . . . . . . . . . . . .. 59
II. Effects of Anaesthesia and Surgery on the Endocrine System
S. Takki and T. Tammisto
Effects of Anaesthesia and Surgery on Catecholamines ..... 69
D.M. Philbin and C.H. Coggins
The Effect of Anaesthesia on Antidiuretic Hormone Levels .. 76
F. Witassek, H. Vetter, G. Hack and M. Marx
Effect of Anaesthesia and Surgery on the Renin-Angiotensin-
Aldosterone System ............................ 83
M.T. Jenkins
Intraoperative Fluids and Hormonal Harmony . . . . . . . . . .. 95
O. Bellmann and H. Stoeckel
The Influence of Anaesthesia on Prolactin Secretion in Man 101
H. Kehlet and M.R. Brandt
Influence of Neurogenic Blockade on the Endocrine Metabolic
Response to Surgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . 112
A. Maeda, H. Ishihara and T. Oyama
The Effect of Anaesthesia and Surgery on Sex Hormones .... 118
III Hormonal and Anaesthetic Management of Endocrine Diseases
F. Kri.ick and K.O. Stumpe
Hormonal Aspects of Hypertension . . . . . . . . . . . . . . .... 131
J .H. Hengstmann
Diagnosis and Perioperative Management of Pheochromocytoma 142
T. Oyama
Anaesthetic Management of Steroid-treated Patients . . . . .. 146
A.H. Giesecke and C.W. Beyer
Anaesthetic Management of Hypophysectomy ........... 150
H. von Ulienfeld-Toal and E. Keck
Consequences of Parathyroid Surgery ................. 153
R.W.C. Janzen, E. Farthmann, M. Doehn and L. Lachenmayer
Thymectomy in Myasthenia Gravis: Pre-and Postoperative
Treatment ................................... 156
F. Willig
Endocrine and Exocrine Treatment After Pancreatectomy ... 162
A. Matsuki and T. Oyama
Shock and Endocrine Function . . . . . . . . . . . . . . . . . . ... 170
M. Siedek and H. Vetter
Renin-and Aldosterone-Regulation in Hepatic Coma Treated
by Baboon Liver Perfusion and in Prolonged Shock ........ 184
K.O. Mosebach
Advantages and Disadvantages of Protein anabolic a ........ 192
Subject Index .................... ............ 199
Contributing Authors
Bellmann, 0., Dr. med., Professor of Gynecology and Obstetrics,
UniversWits-Frauenklinik, D-5300 Bonn-Venusberg, FRG
Beyer, C.W. jr., M.D., Assistant Professor of Anesthesiology Dept.
of Anesthesiology, University of Texas, Southwestern Medical
School Dallas, Texas, USA
Brandt, M.R., M.D., Surgical Dept. C., Rigshospitalet, University
Hospital Copenhagen, Denmark
Breuer, H., Dr. med., Professor of Biochemistry, Institut flir kli
nische Biochemie der Universitat, D-5300 Bonn-Venusberg, FRG
Coggins, C.H., M.D., Assistant Professor of Medicine, Harvard
Medical School, Massachusetts General Hospital, Boston, Mass.,
USA
Doehn, M., Dr. med., Institut flir Anasthesiologie, Universitats
krankenhaus, D-2000 Hamburg-Eppendorf, FRG
Farthmann, E., Dr. med., Professor of Surgery, Chirurgische Uni
versitatsklinik, D-6650 Homburg/Saar, FRG
Giesecke, A.H. jr., M.D., Professor of Anesthesiology, Dept. of
Anesthesiology, University of Texas Southwestern Medical School,
Dallas, Texas, USA
Grote, E., Dr. med., Professor of Neurochemistry, Abteilung
flir klinische Neurochemie und experimentelle Neurochirurgie
Zentrum flir Neurochirurgie, Universitat, D-6300 GieBen,
FRG
Hack, G., Doz., Dr. med., Institut flir Anasthesiologie der Uni
versitat, D-5300 Bonn-Venusberg, FRG
Hengstmann, J .H., Dr. med., Professor of Internal Medicine, Medi
zinische Universitatsklinik, D-5300 Bonn-Venusberg, FRG
Ishihara, H., M.D., Dept. of Anesthesiology, University of
Hirosaki/Japan
Janzen, R.W.C., Doz., Dr. med., Neurologische Univ.-Klinik,
D-2000 Hamburg-Eppendorf, FRG
Jenkins, M.T., M.D., Professor of Anesthesiology, Dept. of Anes
thesiology University of Texas Southwestern Medical School
Dallas, Texas, USA
Keck, E.D., Dr. med., Medizinische Univ.-Klinik, D4000 DUssel
dorf, FRG
Kehlet, H., M.D., Surgical Dept. C, Rigshospitalet, University
Hospital Copenhagen, Denmark
KrUck, F., Dr. med., Professor oflnternal Medicine, UniversWits
Poliklinik, D-5300 Bonn, FRG
Lachenmayer, L., Dr. med., Neurologische Klinik Universitats
krankenhaus, D-2000 Hamburg-Eppendorf, FRG
Lilienfeld-Toal, H.v., Doz. Dr. med., Medizinische Univ.-Klinik,
D-5300 Bonn-Venusberg, FRG
Maeda, A., M.D., Dept. of Anesthesiology University of Hirosaki/
Japan
Matsuki, A., M.D., Dept. of Anesthesiology University of Hirosaki/
Japan
Marx, M., Dr. med., Medizinische Poliklinik der Universitat, D-5300
Bonn, FRG
Mosebach, K.O., Dr. med., Professor of Biochemistry, Institut fUr
Physiologische Chemie der Universitat, Abteilung fUr Physikalische
Biochemie, D-5300 Bonn, FRG
Nocke-Fink, L., Dr. med., Institut fUr klinische Biochemie der
Universitat, D-5300 Bonn-Venusberg, FRG
Oyama, I., M.D., Professor of Anesthesiology, Dept. of Anes
thesiology University of Hirosaki/Japan
Philbin, D.M., M.D., Assoc. Professor of Anesthesia, Dept. of
Anesthesiology Harvard Medical School Massachusetts General
Hospital Boston, Mass., USA
Siedek, M., Dr. med., Professor of Surgery, Chirurgische Univ.
Klinik, D-5300 Bonn-Venusberg, FRG
Siekmann, L., Doz., Dr. med., Institut fUr klinische Biochemie
der Universitlit, D-5300 Bonn-Venusberg, FRG
Stoeckel, H., Dr. med., Professor of Anaesthesiology, Institut fUr
Anlisthesiologie der Universitlit, D-5300 Bonn-Venusberg, FRG
Stumpe, K.O., Dr. med., Professor of Internal Medicine, Medizi
nische Poliklinik der Universitlit, D-5300 Bonn, FRG
Takki, S., Doz., Dr. med., Dept. of Anaesthesia Helsingin kaupun
gin Sairaalavirasto, Helsinki/Finnland
Tammisto, T., Dr. med., Professor of Anaesthesiology, Dept. of
Anaesthesia Helsingin kaupungin Sairaalavirasto, Helsinki/Finn
land
Trede, M., Dr. med., Professor of Surgery, Chirurgische Klinik
Klinikum Mannheim der Universitlit, D-6900 Heidelberg, FRG
Vetter, H., Dr. med., Professor of Internal Medicine, Medizini
sche Poliklinik der Universitlit, D-4400 Miinster, FRG
Wesemann, G., Dr. med., Professor of Neurochemistry, Abteilung
fUr klinische Neurochemie und experimentelle Neurochirurgie
Zentrum fUr Neurochirurgie, Universitlit, D-6300 GieBen, FRG
Willig, F., Dr. med., Professor ofIntemal Medicine, Klinik fUr
innere Krankheiten Krankenhaus Speyrerhof, D-6900 Heidelberg,
FRG
Witassek, F., Dr. med., Medizinische Poliklinik der Universitlit,
D-5300 Bonn, FRG
I. Basic Problems of Endo
crinology in Anaesthesia
and Surgery
