Drug Use today

62 Pages·2016·2.42 MB·English

Drug Use today:
“Legal high” designer drugs and
emerging natural substances.
Presented by: Pat Pizzo, Director
of Toxicology
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Cannabimimetics
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How do these plants effect the user?
Lion’s Tail Dwarf Skullcap
 Euphoria  Relaxing effect
Baybean Siberian Motherwort
 Starry eyed  Cannabinoid like effect
 Smooth smoke  Narcotic effect in animals
Blue Lotus Maconha Brava (False Marijuana)
 Like Viagra  Sedative
Pink Lotus Indian Warrior
 Euphoria  Tranquilizer
 Aphrodisiac
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Synthetic marijuana compounds
Over 450 synthetic marijuana
compounds exist.
The potential to make more is real.
Federal guidelines have banned 5 classes and
24 compounds.
Multiple emergency temporary bans since
the original law was published.
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Statistics and Trends
Monitoring the Future Study: Trends in Prevalence of K2/Spice (Synthetic
Marijuana) for 8th Graders, 10th Graders, and 12th Graders; 2015 (in percent)*
Monitoring the Future Study: Trends in
Drug Time Period 8th Graders 10th Graders 12th Graders
Prevalence of K2/Spice (Synthetic Marijuana)
K2/Spice for 8th Graders, 10th Graders, and 12th
(Synthetic PaGstr aYedaerrs; 2015 (i3n. 1p0ercent)* 4.30 5.20
Marijuana)
NIDA bulletin
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Reasons for Synthetic Marijuana
popularity
Chemical compounds mimic effects of
THC, but may
be 4 to 100 times stronger than marijuana.
Easily modified chemical structures allow
“ ”
chemists
to stay in front of DEA regulations.
Some newer gen products still legal.
Easily distributed and accessible online.
Not typically ordered on routine lab test
panel.
Synthetic Marijuana also known as K2/Spice. Product names continually change. Some common names include: K2,
Spice, K3 Legal, Serenity, Bizzaro, Cloud-9, Avalanche, Sonic Zero, Warped, Haze, Myster, Rain, and many more.
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Alere Toxicology Stats for 2015
54866 specimens tested
0.33% positive rate
Drugs detected in order of most common
URL- 144
JWH – 18
AB- Pinaca
BB22-3CI
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Compound Duration of Effect
THC-Marijuana 2-4 hours
JWH-018 1-2 hours
CP47,497 5-6 hours
HU-210 ~24 hours
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What are the effects?
• Euphoria
• Elevated blood pressure
• Sedation
• Nausea and vomiting
• Perceptual distortions • Seizures – loss of
consciousness
• Appetite stimulation
• Red eyes
• Depressed locomotion (URL44)
• Dry mouth
• Hypothermia (URL44)
• Increased pulse
• Hallucination and delusions
• Thought disruption
• Tachycardia
• Kidney failure (XLR11)
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Federal law banning synthetic
cannabinoids
The Synthetic Drug Abuse Prevention Act signed into law July 2012, bans five
classes of synthetic cannabinoids and 15 specific drugs. Now
 Hydroxycyclohexylphenols  Benzoylindoles
5 Classes
 Naphthoylindoles  Phenylacetylindoles
 Naphthoylpyrroles
 JWH-081 XLR-11 AB-PINACA
CP-47,497
 JWH-122 UR-144
CP-47,497 C8-homolog
 JWH-398 JWH-122
JWH-018 and AM678
15 Drugs
 AM2201 PB-22
JWH-073
 AM694 BB-22
JWH-019
 SR-19 and RCS-4 SF-PB-22
JWH-200
 SR-18 and RCS-8 AB-CHMINACA
JWH-250
 JWH-203 TH-J2201
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