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About Dev and Scale Up in API
This document discusses the process of developing and scaling up active pharmaceutical ingredients (APIs) for manufacturing. It covers the key stages of chemical development, process development and support. Chemical development involves selecting the best synthetic route and optimizing reaction conditions. Process development focuses on further improving yield, efficiency and cost through parameter optimization. Scale-up planning requires considering batch size increases, safety testing, equipment and analytical requirements. The goal is to develop a commercially viable process that can be validated and transferred to full-scale production.
Detailed Information
Author: | ['Sankar Adhikari'] |
---|---|
Publication Year: | 2021 |
Pages: | 34 |
Language: | English |
Format: | |
Price: | FREE |
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