Table Of ContentDENDRIMERS FOR
DRUG DELIVERY
DENDRIMERS FOR
DRUG DELIVERY
Edited by
Anil K. Sharma, MPharm., PhD
Raj K. Keservani, MPharm
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Library and Archives Canada Cataloguing in Publication
Dendrimers for drug delivery / edited by Anil K. Sharma,
MPharm, Raj K. Keservani, MPharm.
Includes bibliographical references and index.
Issued in print and electronic formats.
ISBN 978-1-77188-662-8 (hardcover).--ISBN 978-0-203-71315-0 (PDF)
1. Dendrimers in medicine. 2. Drug delivery systems.
I. Sharma, Anil K., 1980-, editor II. Keservani, Raj K., 1981-, editor
R857.D36D46 2018 615.1'9 C2018-903320-7 C2018-903321-5
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DEDICATION
The present book is dedicated to
our beloved
Aashna,
Anika
Atharva
&
Vihan
CONTENTS
About the Editors.............................................................................................ix
List of Contributors .........................................................................................xi
List of Abbreviations ......................................................................................xv
Preface ..........................................................................................................xix
PART I: PREAMBLE OF NANOMETRIC ARTIFACTS: DENDRIMERS ....1
1. Dendrimers: Branched Nanoarchitectures and Drug Delivery .................3
Raj K. Keservani, Swarnali Goswami, and Anil K. Sharma
2. Dendrimers: A Tool for Advanced Drug Delivery .....................................27
Patrícia Mazureki Campos, Juliana Palma Abriata,
Abayomi Tolulope Ogunjimi, Juliana Maldonado Marchetti, and Robert Lee
3. Dendrimers: General Features and Applications ......................................75
Durgavati Yadav, Kumar Sandeep, Shivani Srivastava, and
Yamini Bhusan Tripathi
4. Computational Approach to Elucidate Dendrimers .................................97
Gurpreet Kaur
PART II: ADVANCEMENTS IN DENDRIMER APPLICATIONS ..............111
5. An Overview of Dendrimers and Their Biomedical Applications .........113
Nirupam Das, Piyoosh A. Sharma, Ankit Seth, Rahul Maheshwari,
Muktika Tekade, Sushant K. Shrivastava, and Rakesh K. Tekade
6. Dendrimers for Controlled Release Drug Delivery .................................185
Phung Ngan Le, Dai Hai Nguyen, Cuu Khoa Nguyen,
and Ngoc Quyen Tran
7. Dendrimers in Targeted Drug Delivery....................................................203
Ankit Seth, Piyoosh A. Sharma, Rahul Maheshwari, Muktika Tekade,
Sushant K. Shrivastava, and Rakesh K. Tekade
8. Dendrimers in Oral Drug Delivery ...........................................................245
Sougata Jana, Joyita Roy, Nilofer Jasmin, Bibek Laha, and Sudipta Das
viii Contents
PART III: DENDRIMERS IN SPECIALIZED THERAPEUTICS ...............271
9. Dendrimers in Gene Delivery ....................................................................273
Piyoosh A. Sharma, Rahul Maheshwari, Muktika Tekade,
Sushant K. Shrivastava, Abhay S. Chauhan, and Rakesh K. Tekade
10. Dendrimers as Nanocarriers for Anticancer Drugs ................................327
Michał Gorzkiewicz and Barbara Klajnert-Maculewicz
11. Dendrimeric Architecture for Effective Antimicrobial Therapy ...........375
Ramadoss Karthikeyan, Oruganti Sai Koushik,
and Palanirajan Vijayaraj Kumar
Index .............................................................................................................411
ABOUT THE EDITORS
Anil K. Sharma, MPharm, PhD
Delhi Institute of Pharmaceutical Sciences & Research, University of
Delhi, India
Anil K. Sharma, MPharm, PhD, is a lecturer at the Delhi Institute of Phar-
maceutical Sciences & Research, University of Delhi, India. He has pub-
lished 28 peer-reviewed papers in the field of pharmaceutical sciences in
national and international reputed journals as well as 15 book chapters and
10 edited books. His research interests include nutraceutical and functional
foods, novel drug delivery systems (NDDs), drug delivery, nanotechnology,
health science / life science, and biology / cancer biology / neurobiology.
He graduated with a degree in pharmacy from the University of Rajasthan,
Jaipur, India, and received a Master of Pharmacy (MPharm) from the School
of Pharmaceutical Sciences, Rajiv Gandhi Proudyogiki Vishwavidyalaya,
Bhopal, India, with a specialization in pharmaceutics. He earned his doctor-
ate (PhD) from the University of Delhi, India.
Raj K. Keservani, MPharm
Faculty of Bachelor Pharmacy, CSM Group of Institutions, Allahabad,
India
Raj K. Keservani, MPharm, is an associate professor at the Faculty of Bach-
elor Pharmacy, CSM Group of Institutions, Allahabad, India. He has more
than 10 years of academic (teaching) experience from various institutes
in India in pharmaceutical education. He has published 35 peer-reviewed
papers in the field of pharmaceutical sciences in national and international
journals. He has also published 16 book chapters, two co-authored books,
and 10 edited books. He is also active as a reviewer for several international
scientific journals. Mr. Keservani graduated with a pharmacy degree from
the Department of Pharmacy, Kumaun University, Nainital (UA), India. He
received his Master of Pharmacy (MPharm) (specialization in pharmaceu-
tics) from the School of Pharmaceutical Sciences, Rajiv Gandhi Proudyogiki
