Table Of ContentCLINICS  IN 
PERINATOLOGY 
Clin  -erinatol  30 (2003) 875  894 
Cumulative  Index  2003 
Volume 30 
March  ETHICS  IN PERINATAL  MEDICINE,  pages  |  7 
June  EVIDENCE-BASED  MEDICINE,  pages  189-438 
September  MATERNAL-FETAL  SURGERY,  pages 439-649 
December  PRETERM  LABOR, pages 651  894 
age numbers of article titles are in boldface type 
\  Aminophylline,  for preterm  labor, 821 
Abacavir,  for HIV  infection,  in pregnancy,  Amniocentesis 
labor and delivery, 862  for anomaly  detection 
emotional  support  for,  115 
Abortion 
failure to inform about,  114 
induced 
premature  membrane  rupture  in,  amnio 
fetal personhood and,  158 
for anomalies,  113—114  patch technique for,  574  580 
availability  of,  117  serial, for twin  twin transfusion 
syndrome, 594-597 
decision-making on, 
113-114,  118  119  Amnionitis.  See  Chorioamnionitis 
legality of, 71] 
Amniotic  fluid 
methods  for,  119  abnormal  volumes of.  See  Oligohydram 
viability  definition and, 
nios;  Polyhydramnios 
119-121 
amniopatch technique involving,  for 
for genetic  indications,  90  9]  premature membrane rupture, 
for nonmedical  reasons,  FIGO  574—580,  586—587 
ethical guidelines for,  57 
culture of, 683  684 
for sex selection, 89  in gastroschisis,  559  564 
selective.  See  Selective termination  exchange or  infusion of, 561  564 
terminology  recommendations  for, 20 
inflammatory  effects of, 559  S61 
Academ3i]c  p3e2r93 f ormance,  follow-up data in,  Amoxicillin,  for intrauterine  infections, 
688 — 689, 69] 
Acardiac twin,  in twin reversed arterial  Ampicillin,  for intrauterine infections, 687,  689 
perfusion sequence, 602-603 
Amprenavir,  for HIV  infection,  in pregnancy 
Access to care,  in managed care,  |7 2  ha  labor and delivery, 863 
Anastomoses,  placental, in twin—twin 
AIDS.  See  Human immunodeficiency 
transfusion syndrome,  592—593 
Virus  infection 
Anencephaly,  viability questions in,  119-12] 
American College of Surgeons, guidelines of, 
for maternal-fetal  surgery,  142  \neuploidy, nuchal translucency  screening for, 
95-102 
American Society  for Reproductive Medicine  reliability  of, 95  98 
Ethics Committee, on gender selection,  respect for autonomy  in,  100 
75  5 
risks versus benefits of, 9&8  99 
0095-5108/03/$ — see front matter  «  2003  Elsevier Inc.  All rights reserved 
doi: 10.1016/S0095-5 108(03)00126-X
Cumulative Index / Clin Perinatol 30 (2003) 875-894 
Anhydramnios  Benchmarking techniques, 343-350 
in fetal distal urinary  obstruction, 507  abuses of, 347 
511-512, 515  limitations of, 345 
in gastroschisis, 553  patient protection  in,  348 
to improve quality of practice,  348 
Anomalies,  fetal.  See  Fetus, anomalies in 
uses of, 344-346 
Antenatal surgery.  See  Maternal -— fetal surgery 
Beneficence 
Antibiotics  in fetal anomaly  management,  122-123 
for asymptomatic premature infants,  in maternal  —fetal surgery  for spina 
treatment decisions in.  See  bifida, 456—457 
Treatment decisions  in nuchal translucency  screening, 98-99 
for intrauterine  infections, 687-691,  Bentham, Jeremy, ethics theory of, 6 
718-720 
for preterm premature rupture of  Beta-adrenergic agonists,  for preterm labor, 
membranes, 828 — 829  818—820 
Aortic  stenosis, treatment of, 544—54  Beta-sympathomimetic agents, for preterm 
labor, 817-820 
\pnea,  neonatal,  methylxanthines  for, 
treatment  decisions  in.  See  Betamethasone, antenatal,  for fetal maturation, 
829-833 
Treatment decisions 
Arachidonic acid, in prostaglandin synthesis, in  Biopsy, kidney, in distal urinary  tract 
uterine activity,  807  obstruction,  513 
Ascites, in distal urinary  tract obstruction,  510  Bipolar coagulation, of umbilical cord,  in 
multifetal  pregnancies, 611—616 
Assisted reproduction technologies 
multifetal  pregnancy  in.  See  Birthweight, in multifetal  pregnancy, selective 
Multifetal pregnancy  reduction effects on,  106-107 
preterm birth risk with, 659 
Bladder 
\tazanzvir,  for  HIV  infection,  in pregnancy,  embryology  of, 508 
labor and delivery, 863  obstruction of. See  Urinary  tract 
obstruction, distal 
\tosiban,  for preterm labor, 822, 849 
Blastocyst, 29,  39 
\trial septum, intact,  treatment of, 545-546 
Blastomeres,  29 
\utonomy 
in decision-making about fetal anomalies,  Bleeding, vaginal, preterm birth in, 657 
118-119 
Blood transfusions,  refusal of, in pregnancy, 
in maternal — fetal surgery  for spina  130—131.  135 
bifida, 453—455 
reproductive freedom component of, 114  Brain death,  36 
respect for, in nuchal translucency 
screening,  100  Braxton  Hicks contractions,  809-810 
Breastfeeding, avoidance of, in HIV 
infection, 872 . 
Bronchopulmonary  sequestration 
B  diagnosis of, 482—483 
Bacterial vaginosis, preterm birth in, 655-656,  natural history of, 484 
686-687, 690-691  size of, 481 
surgical treatment of, 486-487 
Balloon 
for tracheal occlusion,  in congenital 
diaphragmatic hernia,  469—473 
for valvuloplasty.  See 
Valvuloplasty, balloon 
C  -_————— 
Bayley Scales of Infant Development,  Calcium, in uterine activity, 806-807 
follow-up data in, 228 
Calcium  channel  blockers,  for preterm  labor, 
Bedrest,  for preterm labor, 813—814  820-821, 849-850
Cumulative  Index / Clin Perinatol  30 (2003)  875-894 
apitation, in managed care,  170  corticosteroids  for, 830 
diagnosis of, 679 
arder,  Angela, court-ordered cesarean section  mechanisms of,  684 
on,  129-134  organisms causing, 683-684 
are, access to, in managed care,  172—173  origin of, 685 
premature rupture of membranes 
atheters  in, 691 
for thoracoamniotic  shunting, 485—486  treatment of,  687-691 
for vesicoamniotic  shunting,  513—515  versus gestational  age, 681  —682 
ephallalo centesie s, i  in hydrocecpehaplnuasl,u s,  533  Chorionic villi sampling 
before multifetal  pregnancy 
erebral palsy, motor development  in  reduction, 632 
227-228 
before selective reduction,  108—  109 
premature membrane rupture in, 
ervicovaginal  fibronectin.  See 
amniopatch technique fot 
Fibronectin,  fetal 
574-580 
ervix 
Chromosomal abnormalities 
incompetence of 
in discordant twins,  603 
preterm labor in, 808—809 
ultrasound evaluation of,  749-752  in gastroschisis,  $52 
in multifetal  pregnancies, 605-606, 
length of,  preterm birth risk and, 654 
631—632 
preparation of, for labor, 810 
1  twin reversed arterial perfusion 
ultrasound evaluation of, 735—755 
sequence, 602 
in preterm  birth prediction, 
738—749  selective  termination  for.  See 
Selective termination 
cervical  incompetence  in, 
749~—752  hronic lung disease,  prevention of 
in asymptomatic  women,  dexamethasone  in, evidence-based 
738-741.  744-747  decision-making  in, 238—239 
in multifetal  pregnancy, 
lewell,  William,  maternal -— fetal surgery 
146—747 
in singleton pregnancy,  research by, 442—445 
744-749 
lindamycin,  for intrauterine  infections, 689 
in symptomatic  women, 
742-743  ochrane neonatal systematic revie 
landmarks  for, 736  285-304,  335-33 6,  391 
technique for, 736—738  results of, 28  299 
versus clinical examination  characteristics of included trials, 
288—289 
Cesarean delivery  distribution across  subject 
for HIV  infection,  865, 868  areas, 288 
for nonmedical  reasons,  FIGO ethical  growth of output, 287 
guidelines  for, 53—54  observations on review 
managed care impact on  methodologies,  299-300 
refusal of  reviewers’ conclusions,  291, 299 
legal issues  in,  129—133  size and precision of estimate of 
survey  on,  134-139  treatment effect, 290—291 
size of reviews,  290 
Chemical phenomenon,  in gastroschisis,  553 
therapies with extensive  versus 
Chiari malformation, with myelomeningocele,  limited testing, 291] 
523-526 
survey  methods in,  286—287 
Chorioamnionitis  Cognitive development,  follow-up data in, 
in maternal-—  fetal surgery,  for  lung  228-230 
lesions, 487 
neonatal outcomes  in, 685  Common sense,  in ethics, 9 
preterm birth in, 655—656  ‘ommunication,  17—25 
asymptomatic, 681  alternative word choices for, 
chronicity  of, 682-682  discriminatory,  18—19 
clinical  features of, 680  impact on memory,  17—18
Cumulative Index / Clin Pe rinatol 30 (2003) 875-894 
importance of, 17-18  in preterm premature rupture of 
medical  language for, 19  membranes, 828—  830 
obstetric language for, 20  National  Institutes of Health 
of fetal anomaly  test results,  115—117  recommendations on, 836—837 
prenatal diagnosis language for, 20—24  single versus multiple courses of, 
sexist,  18—19  833-835 
Confidentiality, of genetic data, 87-88  Council of Europe, ethics code of, 51 
Congenital anomalies. See  Fetus, anomalies in.  Counseling 
Congenital cystic adenomatoid malformation,  on fetal anomalies 
of lung, 481-492  postviability,  122—124 
animal studies of, 484-485  previability,  118-119 
clinical features of, 481  on selective termination,  in multifetal 
diagnosis of, 482—483  pregnancies, 604-606 
natural history of, 484  Cryoprecipitate,  in amniopatch,  for premature 
pathology  of, 482  membrane rupture,  574-580, 586—587 
size of, 482 
surgical treatment of, 485—488  Culture, of amniotic  fluid, 683—684 
types of, 482  Cystic adenomatoid  malformation  volume 
Congenital diaphragmatic hernia, 465-479  ratio, 484 
animal studies of, 467 
Cystoscopy, for distal urinary  tract obstruction, 
delivery  with, 473-474 
515-516 
incidence of, 465 
mortality  in,  465, 467, 475  Cytogenetic  analysis,  in multifetal 
natural history of, 466—467  pregnancies, 605 
prognosis  for, 466—467 
Cytokines 
treatment of 
postnatal, 474—475  in chorioamnionitis, 679, 684 
prenatal, 467  —473  in gastroschisis,  557—558 
ultrasonography  in, 466—467  in preterm birth, 655—65 
Congenital  heart disease, 541-550  Cytomegalovirus  infections,  preterm birth 
diagnosis of, 542—543  in,  694 
etiology  of, 543 
in gastroschisis,  554-555 
treatment  of 
anesthesia  in, 547  D 
aortic stenosis,  544 
daVinci system,  for maternal -— fetal 
intact atrial septum, 
surgery,  528 
mitral stenosis,  545 
rationale for, 543  —544  De Lia, Julian, maternal — fetal surgery  research 
right-sided defects,  546  by, 445-446 
techniques for, 547-548 
Death 
onsequentialism, 6  fetal,  in maternal  infections, 692—694 
maternal, pregnancy  management 
onstr5ic5t2i-ve5 53p henomenon,  in gastroschisis,  guidelines for, 53 
Decision-making 
ontractions,  uterine.  See  Uterus, contractions 
of; Home uterine activity  monitoring.  evidence-based.  See  Evidence-based 
decision-making. 
‘orpus luteum, ultrasonography  of, 39  in genetic counseling, 84—86 
in preimplantation diagnosis, of Down 
orticosteroids, antenatal,  for fetal maturation, 
syndrome, 74—75 
$27—842 
on abortion 
American College of Obstetricians and 
for anomalies,  113—114,  118—119, 
Gynecologists opinion on, 837 
122-124 
drug selection  for, 830—833 
for trisomy  13, 121-122 
effects of, 827-828 
for trisomy  18, 121-122 
evidence-based decision-making in, 
409-412  Declaration of Helsinki, 60—63
Cumulative  Index / Clin Perinatol 30 (2003) 875-894 
Delavirdine,  for HIV  infection, in pregnancy,  Drainage 
labor and delivery, 862  in thoracoamniotic  shunting, 485—486 
in vesicoamniotic  shunting, 513—515 
Delivery, managed care impact on,  175  of sacrococcygeal  teratoma, 
Denver shunt, in hydrocephalus,  534—535  497-498,  501 
Dystocia, with large sacrococcygeal 
Deontology,  6 
teratoma, 494 
Department of Health and Human Services, 
maternal-fetal surgery research guidelines 
of,  146-152 
Economic  issues 
Dexamethasone  in managed care,  169—171 
antenatal,  for fetal maturation,  829—833  in multifetal pregnancies, 624—6 
to prevent chronic lung disease,  in preterm birth, 666,  757—758 
evidence-based decision-making in,  home uterine activity  monitoring 
230-230  impact on, 783—784,  787 
Diagnostic tests,  189-204  Education,  in ethics,  1-15 
benefit of, to patient, 201  —22 02  core generic course  in,  11—13 
posttest probability  of disease and, 20]  for perinatal medicine,  13 
pretest probability  of disease and, 201  impact of, 13-14 
reproducibility  of, 201  introduction to,  10-11 
research  literature on,  197—202  phases of,  10-13 
case scenario in,  197, 202  principles of 
search of, for best available study  definitions of,  | 
197-198  medical ethics v 
study appropriateness  in,  199—200  ethics, 2 
study  validity  in,  198-199  moral certainty, 
screening,  196-197  reasoning,  3—5 
sensitivity,  specificity,  and likelihood  trust, 6-9 
ratio in,  190—  191,  200  process of, 9-10 
purpose of, 9-10 
Diaphragmatic hernia.  See  Congenital 
theories for, 6-8 
diaphragmatic hernia 
favirenz,  for HIV  infection,  in pregnancy, 
Diazoxide,  for preterm labor,  822  labor and delivery,  863 
Didanosine,  for  HIV  infection,  in pregnancy,  lectrical  properties,  of  myometrium 
labor and delivery, 859-860,  862  667—  669 
Diltiazem,  for preterm labor, 849-850  lectromyography,  uterine,  670—674 
Disability  mnbbdoolt zatioj n, Of f uummbbiilliiccaall   vev essel]s ,  inn  secleelcetcitivvee  
prevention of, with preimplantation  termination,  in multifetal  pregnancies, 
genetic diagnosis, controversy  over  606—  608 
ms 
mbryo(s) 
threat of, maternal—fetal  surgery  for 
as beginning ol human  life,  32 
spina bifida and,  459-460  definition of,  36 
extracorporeal, moral status of, 70—71 
Doppler studies, in congenital heart disease, 
research on, ethical  issues  in,  36—37 
542  —543, 545 
transfer techniques for, preterm birth risk 
Down syndrome  in, 659 
nuchal translucency  screening  for,  ultrasonography  of, 40—42 
95-102  Embryo-chorionic circulation, ultrasonography 
reliability  of, 95—98 
of, 40 
respect for autonomy  in,  100 
risks versus benefits of, 98-99  Embryogenesis,  29—30 
preimplantation diagnosis of,  Emotional development, follow-up data in, 230 
decision-making in, 74—75 
prenatal detection of, failure to inform  Emotional support, for fetal anomaly detection 
about,  114  and management,  115
880  Cumulative Index / Clin Perinatol 30 (2003) 875-894 
Emtricitabine, for HIV infection, in pregnancy,  United Nations Educational, 
labor and delivery, 862  Scientific, and Cultural 
Organization, 50 
Endometrium, microorganism colonization of,  World Health Organization, 50—51 
preterm birth in, 656  communication and, 17—25 
definition of, 45 
Endoscopy,  for premature ruptured membrane 
education  in,  1-15 
assessment,  580—584 
evidence-based.  See 
Enfuvirtide,  for HIV infection, in pregnancy,  Evidence-based ethics. 
labor and delivery, 863  of beginning of human life, 27—44 
of fetal anomaly  screening,  113-126 
EnI zymtehi-e-l inkeCdC   immunoNOsSoCr benc t aassssc ay  of genetic counseling, 81-93 
for fetal fibronectin,  704  of managed care,  167-180 
for salivary estriol, 721  of maternal — fetal surgery 
for congenital heart defects, 543 
Equipoise criterion,  in maternal-fetal  surgery  for multifetal  pregnancy  reduction, 
for myelomeningocele,  162-163 
623-624 
for myelomeningocele,  155-165 
Erythromycin, for intrauterine  infections, 
for spina bifida, 449-464 
687—691  autonomy  in, 453—455 
Estriol, salivary, as preterm birth predictor,  beneficence in, 456—457 
at  ss  clinical emphasis in, 451 
20  2 
background of, 720—723  controversy  over, 449—450 
elective interventions  in, 
confounding factors in, 72!  —7423 
in asymptomatic women,  723—724  458 — 459 
in multifetal  pregnancy,  726  moral ideas on, 451] 
in symptomatic women,  724-726  457-458 
intervention  studies of, 726—727  potential abuse of, 461  —462 
predisposition to treatment in, 
Ethanol,  for preterm  labor, 815—816  460-461 
religious context of, 452—453 
Ethics  risk considerations in, 
codes of, 45-65  457—458 
Council of Europe, 51 
threat of disability  in, 
FIGO (International  Federation of  459-460 
Gynecology  and Obstetrics)  uncertainty  in,  45; 
Committee,  for Study of  vulnerability  in, 454 
Ethical  Aspects of Human  in research programs,  141 
Reproduction, 51  —58  of nuchal translucency  screening, 
for cesarean delivery  for 
95-102 
nonmedical  reasons,  53  —54  of preimplantation diagnosis. See 
for induced abortion  for  Preimplantation genetic diagnosis 
nonmedical reasons,  57—59  of refusal of treatment,  127-140 
for management of newborns at 
of selective reduction,  103-111 
threshold of viability, 54—56 
for management of severely  Ethnic factors, in preterm birth, 651, 656 
malformed newborns, 56—57 
Eugenics, 86—87 
for pregnancy  management  in 
sudden maternal death, 53  Evidence-based decision-making. See also 
for prenatal diagnosis, 52—53  Therapeutic evidence; 
for research on human subjects,  Treatment decisions. 
59-63  follow-up data in, 217-250 
from hospital ethics committees,  choice of outcomes to study, 
46—48  ,) ] g  224 
from international ethics  examples of, 238—240 
committees, 49—58  group difference in, 233, 237—238 
from national ethics committees,  health-related quality of life, 224 
48—49  neonatal outcome as predictor 
new  technology  impact on, 45-46  of, 225 
patient-physician relationship  neurodevelopment after age 2, 
and, 46  999  , 39
Cumulative  Index / Clin Perinatol  30 (2003)  875-894  881 
academic performance,  curriculum evaluation  in, 430—431 
y2 5  329  obtain  information  with  maximum 
cognitive development,  efficiency, 426—428 
229-230  recognize need for information and 
motor  development, 229  put in form of answerable 
social and emotional  question, 425-426 
deveiopment,  230  strategies  for, 421—423 
neurodevelopment at | to 2 years of  to faculty, 425 
age, 226—228  to medical students, 423-424 
cognitive development,  228 
hearing assessment,  2) 26  97  to residents and fellows, 424—425 
motor development, 227—228  Evidence-based ethics,  for extremely 
vision assessment,  227  premature  infants, 363—387 
no group difference  in, 232-233  based on credible evidence,  366 
in neonatal  intensive care unit.  Sec  boundaries  for care categories  in, 
Neonatal  intensive care unit  379-38]  : 
promoting  uptake and use of, 389-402,  chance of survival and,  366 
403-417  cost-effectiveness  in,  373—375 
analysis of uptake process,  definition of, 364 
404-405  effects on families  in,  377 
clinician awareness of ry p T oven  futility  of care,  364—366 
therapies, 391  —39  405-406  need for improved  studies of, 381 
clinician  belief in evidence,  406  outcome  measurements  in,  368-369 
clinician commitment  to  patient  factors in,  369-373 
change, 407  preventing quandaries in,  382—383 
definition of effectiveness  roles of parents and physicians in, 
389-39]  23770 8—(3#27 9 
dissemination of new  information, 
treatment  withdrawal  in,  377 
393-397  types of therapeutic  studies in,  367 
clinician  factors  in,  396—397 
use of resources  and distress to infants 
comparison of methods  for, 
394-396  versus  benefits,  375—376 
evaluation of new  therapies  Ex utero  intrapartum treatment  (EXIT),  1 
390-39]  congenital diaphragmatic  hernia, 
evidence to support particular  473-474 
strategy, 405 
examples of, 409-415  Experimental  therapy,  in managed care,  173 
antenatal  steroids  for  fetal  Extracorporeal  membrane oxygenation,  for 
maturation, 409—412  congenital diaphragmatic  hernia, 
National  Partnership to Help  474-475 
Pregnant Smokers Quit 
412-414 
smoking cessation  in routine 
care, 414-415 
implementation,  monitoring, and 
maintenance of change,  408  Fee for service,  negotiated,  in managed care, 
inappropriate underuse of proven  1ri7O e—  hs7 1 
therapies,  397-399  Feminist ethics, 7 
peer endorsement of evidence, 
406-407  Ferritin,  in gastroschisis,  558 
perception of gap between practice 
Fertilization 
and evidence, 407 
in vitro, multifetal pregnancy  in, selective 
support  for change by practice 
reduction  in,  103—111 
setting, 407—408 
life beginning at 
synergistic effects of interventions,  ‘ 
arguments against,  32—33 
408  —409 
arguments  for, 31  —32 
teaching of, 419—433 
apply information to problem and  Fetoscope 
evaluate outcome, 429-430  iatrogenic  membrane  rupture  from,  am- 
critically appraise evidence,  niopatch technique for, 574—580 
428—429  invention of, 440-441
882  Cumulative  Index / Clin Perinatol 30 (2003) 875-894 
Fetus  Financial considerations,  in genetic 
anomalies in,  113-126  counseling, 92 
communication about  Fluid therapy, for preterm labor, 814 
See Communication 
lethal, hospice care in,  123  Formulary,  limited, in managed care,  173 
management of 
aggressive,  117,  122—124 
balancing approach to, 
ii7,  123  Gamete  intra-fallopian transfer, preterm birth 
nonaggressive,  117,  122~—12 4  risk in,  659 
options for,  117  Gastroesophageal  reflux, treatment  decisions 
postviability  counseling and  in.  See  Treatment decisions 
decision-making on, 
122-124  Gastroschisis, 551—572 
amnioexchange and amnioinfusion 
preimplantation detection of. 
procedures for, 561—564 
See  Preimplantation  amniotic  fluid impact on, 559-562 
genetic diagnosis  animal models of,  557—559 
previability  counseling and  consequence S  ea  53 
decision-making on,  118—  119  delivery  in, 55¢ 
screening and detection of  diagnosis of, 55 
emotional  support in,  115 
ethical basis of,  113-114  genetic factors 1n, 
giving bad news after,  historical review  of, 5 
115-117  incidence  of, 551] 
selective reduction  for,  108—  109  inflammation  in, 
monitoring  of, 
viability  definition and,  119~—  122 
outcome of, 55: 
fibronectin  related to.  Sec  postnatal care  in, 554 
Fibronectin,  fetal  prognosis  for, $55—55 
genetic counseling related to.  See Genetic  surgical treatment of, 554 
counseling. 
maturation of, antenatal steroid therapy  Gender 
in.  See Corticosteroids, antenatal,  medical  language insensitive to,  19 
prebirth selection  for, 75—77,  89 
for fetal maturation 
sexist  language and,  18 — 19 
personhood of, 31, 156-160,  449-452 
research on, ethics guidelines for, 62—63  Gene therapy, preimplantation genetic 
surgery  on.  See Maternal  -—fetal surgery  diagnosis and, 92 
ultrasonography  of,  3D and 4D, 41  —42  Genetic  counseling, 81—93 
viability  of. See  Viability, of fetus  counselor responsibilities in, 84—86 
or newborn.  decision rights in, 84—86 
directive,  82 
Fibrin formation, in amniopatch technique, 578 
discrimination  resulting  from, 88  —89 
ib.in glue, for premature rupture of  history  of, 81—82 
membranes,  585—586  illness versus health considerations in, 
89-90 
Fibronectin,  fetal  means of, 82—84 
as preterm birth predictor, 702  nondirective, 82, 84—86 
assays for, 704—705  on financial costs, 92 
confounding  factors in, 705  on monogenic diseases,  86—87 
historical background of, 702—705  on pregnancy  termination, 90—91 
in asymptomatic women,  706—709  on preimplantation diagnosis, 92 
in multifetal gestations,  714—717  on presymptomatic diagnostics, 
in symptomatic women,  710—714  confidentiality  of data and, 87—88 
intervention  studies of,  17-720  on sex selection and determination, 89 
in normal pregnancies,  702-704  religious considerations in, 91  —92 
stigmatization resulting from, 88—  89 
FIGO (International  Federation of Gynecology 
and Obstetrics) Committee,  for Study of  Gestational age 
Ethical Aspects of Human Reproduction,  at delivery, tocolysis effects on, 852 
51-58  versus intrauterine  infections, 681  —682
Cumulative  Index / Clin  -erinatol 30 (2003)  875-894 
follow-up care  in, 871 
Harrison,  Michael, maternal — fetal surgery  eneral laboratory  testing in, 859-860 
IIV  testing in, 858—859 
research by, 441-442 
neonatal care  in, 871—872 
Health, versus  illness,  genetic counseling  obstetric procedures in, 868—869 
89—90  postpartum care in, 871 
Health maintenance organizations.  Se¢  viral transmission  prevention  in, 
860-868 
Managed care 
Hearing assessment,  follow-up data in,  Hydrocephalus, 443  —445, 531-539 
196  227  anomalies associated with,  531  —53 
classification of, 531 
Heart disease, congenital.  See  Congenital 
heart disease  etiology 
morbidity  and mortality  in, 
Hernia, diaphragmatic.  See  Congenital  534—535 
diaphragmatic hernia  :  h  <9 
myelomeningocele with,  52 
Highly active antiretroviral  therapy, for HI\  prevalence of, 531 
infection,  in pregnancy,  labor and  treatment of, 533—538 
deliv ery  861  Hydronephrosis,  in distal urinary  tract 
HIV  infection.  See  Human  immunodeficiency  obstruction,  510 
virus  infection 
Hydrops 
Home uterine activity  monitoring,  757—804  in lung lesions, 481—486 
after tocolysis  787-791  in sacrococcygeal  teratoma, 495  SUS 
clinical trials overview  of, 759 
Hydroureters,  in distal urinary  tract 
comprehensive system versus 
obstruction,  510 
self-palpation,  767—768 
controversy  over,  759-760  7-a-Hydroxyprogesterone,  for preterm 
devices  for, 765—766  labor, @98272  
during maintenance tocolytic therapy, 
793—797  Hyperglycemia,  from ritodrine, 819-820 
economic  impact of, 783—784,  78  Hypnotics,  for preterm  labor, 821  —822 
false versus true,  766 
frequency  of, 764—765  Hypoplastic  left heart  syndrome 
in multifetal  pregnancy,  765, 781  —782  in aortic stenosis,  544—545 
in secondary  prevention clinical  trials,  in intact atrial septum,  545—546 
768787  in mitral stenosis,  545 
in socioeconomically  disadvantaged  Hypoplastic right heart syndrome,  543, 546 
group,  783—784 
Hypotension,  in prem1a ture  infants,  inotropes 
In tertiary  prey ention clinical trials, 
87—791  for, treatment  decisions  in.  See 
indications  for,  75  59  Treatment decisions 
miscellaneous studies on,  79] 
preterm contractions,  764—765 
preterm labor  symptoms and, 766—767 
protocol  for, 761~—  764 
recording  strips produced in, 76] |  Illness, versus health, genetic counseling and, 
89-90 
Hospice care,  in lethal  fetal anomalies, 
123-124  Implantation, as beginning of human life,  33 
Hospital ethics committees,  46—48  In vitro fertilization 
multifetal  pregnancy  in, selective 
Human Genome  Project, genetic counseling 
reduction  in,  103-111 
and, 86~—87 
preterm birth risk in, 659 
Human immunodeficiency  virus infection, 
Incompetence, cervical, ultrasound evaluation 
preterm labor in, 857—876 
of, 749-752 
antenatal care in, 871] 
clinical situations  in, 869—8  0  Indinavir,  for HIV  infection,  in pregnancy, 
delivery  mode in, 865  labor and delivery, 863
884  Cumulative Index / Clin Perinatol 30 (2003) 875-894 
ndomethacin  International  Fetal Medicine and Surgery 
for preterm labor, 816—817, 847, 849  Society, 444 
prophylactic, in low birth weight infants, 
International  Fetoscopy  Group, 440-441 
evidence-based decision-making in, 
239-240  Intestine 
Infections  exteriorization  of, in gastroschisis, 5 
pathology  of, in gastroschisis,  553—554 
neonatal effects of, 687 
preterm birth in, 655—656,  Intrauterine growth retardation 
677-700, 809  after multifetal pregnancy  reduction, 631 
ascent of, 686  in gastroschisis, 554, 563 
asymptomatic, 68|  
bacterial vaginosis, 686-687  Intrauterine pressure catheters,  for preterm 
chronicity  of, 682-683  labor detection, 667 
diagnosis of, 679—680  Isoxuprine,  for preterm labor, 818 
fetal death in, 694 
fetal fibronectin  in, 704, 717—720 
historical review  ot, 677-679 
markers of, 680 
mechanisms of, 684  Justice principle, preimplantation genetic 
organisms causing, 683 — 684  diagnosis and, 69 
origin of, 685 
premature rupture of membranes 
in, 691 
sexually transmitted, 691, 693-694  K  - 
Kant, Immanuel, ethics theory of, 6 
treatment of, 687-691 
types of. 680—681  Karyotyping, for genetic diagnosis in selective 
versus gestational age,  681 — 682  reduction,  108-109 
viral, 694 
Keratinocyte growth factor, in congenital cystic 
Infertility, treatments  for  adenomatoid  malformation, 482 
multifetal pregnancy  in,  103 
religious teachings on,  34  Kidney 
biopsy of, in distal urinary  tract 
Inflammation,  in gastroschisis,  557  obstruction,  513 
562  —564  damage of, in urethral obstruction, 
Informed choice, in maternal -— fetal surgery  for  507-510 
spina bifida, 460—461 
Informed consent 
for nuchal translucency  screening,  100 
for preimplantation genetic diagnosis, 69  Labor and delivery.  See also Cesarean delivery 
diagnosis of 
Inotropes, for hypotension, in premature 
clinical, 666-667 
infants, treatment decisions in.  See 
electromyography  in, 670-674 
Treatment decisions 
in congenital diaphragmatic hernia, 
Intensive care unit, neonatal.  See  under  473-474 
Neonatal  intensive care unit  in gastroschisis,  555 
in HIV  infection, 865, 868 
Interleukin(s),  in gastroschisis,  557—558,  in hydrocephalus, : 533-534 
562-563  in large sacrococcygeal  teratoma,  494 
International ethics committees  premature. See Premature  labor 
codes of, 49—58  and delivery. 
Council of Europe, 5  preparatory  stage of, 669-670 
United Nations Educational,  Scientific, 
Lamivudine,  for HIV  infection,  in pregnancy, 
and Cultural Organization, 50 
labor and delivery, 862, 864 
World Health Organization, 50-51 
Language. See Communication 
International  Federation of Gynecology  and 
Obstetrics (FIGO) Committee,  for Study  Laser therapy 
of Ethical Aspects of Human  for premature rupture of membranes, 
Reproduction, 51  —58  584-586