Table Of ContentCONTENTS
NUMBER 1, JANUARY
Preface: Professor A. L. A. Boura
J. O’Neil and J. Olley
Autacoids affecting vascular tone in the human fetal extracorporeal circulation
W. A. W. Walters
Cardiovascular sensitivity changes to eicosanoids in rats with experimentally induced diabetes mellitus
W. C. Hodgson, B. W. Sikorski and R. G. King
Chemical design of peripherally acting compounds
W. R. Jackson, F. C. Copp, J. D. Cullen, F- J. Guyett, I. D. Rae, A. J. Robinson, H. Pothoulackis, A. K. Serelis and
M. Wong
Pharmacological evaluation of two novel analogues of mianserin: 2-N-carboxamidinonormianserin (FCC5) and 2-N-
carboxamidonormianserin (FCC13)
I. M. Leitch, A. Rawlow and M. P. Rechtman
Sensory nerves in the airways as a target for drug development
M. P. Rechtman
The evolution of hypertensive therapy
R. D. Robson
Buprenorphine and gastrointestinal transit in rats: Effect of naloxone on the biphasic dose—response curve
A. Cowan
An industrial approach to drug discovery: A pharmacologist’s eyeview
J. M. Armstrong and P. E. Hicks
Government initiatives in the development of a pharmaceutical industry in Australia
C. A. Hirst
AMRAD: The first 4 years
J. P. Grace
Symbiotic relationship between a research institute and a pharmaceutical company: The Baker Institute/Glaxo Australia
story
J. A. Angus
GABA, agonists as targets for drug development
G. A. R. Johnston
NUMBER 2, FEBRUARY
Relationship between ATP resynthesis and calcium accumulation in the reperfused rat heart
Y. Hasin, M. M. Kneen, D. J. Craik and W. G. Nayler
Antagonism by endothelin of centrally mediated cardiovascular effects of potassium in anaesthetized rats
J. Shah and B. S. Jandhyala
Impedance measurement during ait and helium—oxygen breathing before and after Salbutamol in COPD patients
E. F. M. Wouters, F. J. Landser, A. H. Polko and B. F. Visser
Activation of noradrenergic and nitrergic mechanisms in the rat anococcygeus muscle by nicotine
M. J. Rand and C. G. Li
Plasma phospholipase A: activity in clinical acute myocardial infarction
L. L. L. Leong, M. J. Sturm, Y. Ismail, C. J. Stephens and R. R. Taylor
Superoxide dismutase attenuated post-ischaemic contractile dysfunction in a myocardial xanthine oxidase deficient species
H. Ooiwa, T. Miura, T. Iwamoto, T. Ogawa, R. Ishimoto, T. Adachi and O. limura
Repetitive electrical activity of the muscle membrane induced in chloride-free medium
P. P. Nanasi and M. Danko
Blood serum biochemical changes in physically conditioned and unconditioned subjects during bed rest and chronic
hyperhydration
Y. G. Zorbas, K. A. Naexu and Y. F. Federenko
Contents
NUMBER 3, MARCH
Review Article . =
Nitrergic transmission: Nitric oxide as a mediator of non-adrenergic, non-cholinergic neuro-effector transmission
M. J. Rand
Increased Na*/H* exchange activity in vascular smooth muscle cells of spontaneously hypertensive rats and possible
involvement of protein kinase C
H. Inariba, Y. Kanayama, K. Takaori, N. Negoro, T. Inoue and T. Takeda
Fish oil feeding selectively attenuates contractile responses to noradrenaline and electrical stimulation in the perfused
mesenteric resistance vessels of spontaneously hypertensive rats
Z. M. Chu, K. Yin and L. J. Beilin
Propofol anaesthesia in malignant hyperpyrexia susceptible swine
P. S. Foster, K. C. Hopkinson and M. A. Denborough
Cardiovascular habituation to emotional stress in Lyon hypertensive rats
C. Julien, J. Sacquet, P. Kandza, D-F. Su, M. Vincent and C. Barres
Atrial and brain natriuretic peptides: Secretion during exercise in patients with essential hypertension and modulation by
acute angiotensin-converting enzyme inhibition
M. Kohno, T. Horio, K. Yokokawa, K. Murakawa, K. Yasunari, N. Kurihara and T. Takeda
Renal handling of endogenous lithium in experimental diabetes mellitus in the rat
C. A. Pollock and M. J. Field
Obituary: Professor K. P. Bhargava
NUMBER 4, APRIL
Regulation of proximal tubule function by angiotensin
P. J. Harris
Inhibitory effect of neuropeptide Y on stimulated renin secretion of awake rats
J-F. Aubert, P. Walker, E. Grouzmann, J. Nussberger, H. R. Brunner and B. Waeber
Failure of the nitrous oxide tissue equilibration method for the determination of brain and myocardial blood flow under
controlled conditions
M. A. Reid, W. B. Runciman, C. F. McLean and L. E. Mather
Sodium and noradrenaline in cerebrospinal fluid and blood in salt-sensitive and non-salt-sensitive essential hypertension
Y. Kawano, K. Yoshida, M. Kawamura, H. Yoshimi, T. Ashida, H. Abe, M. Imanishi, G. Kimura, S. Kojima, M. Kuramochi
and T. Omae
Potassium channel activation improves blood flow pattern of conscious rats in cutaneous microcirculation
R. F. Hertel
Time course of regional flow distribution following reperfusion of the isolated ischaemic rat heart
P-O. Sjoquist, T. Abrahamsson and M. H. Johansson
Isolation and characterization of the rat liver AVP receptor using [!25I][d(CH2)s’Sarcosi|nAVeP’!
D. Trinder, J. M. Kelly, R. Fernley, V. Mooser, P. A. Phillips and C. I. Johnston
Increased sensitivity to endothelin-! in isolated Krebs’-perfused kidneys of streptozotocin-diabetic rats
P. J. Tammesild, W. C. Hodgson and R. G. King
Measurement and identification of prorenin and renin in ovarian follicular fluid from cattle and pig
A. Hagemann, A. H. Neilson, V. Dantzer, B. Avery, K. Poulsen
Letters to the Editor
NUMBER 5, MAY
Communications from the High Blood Pressure Research Council of Australia
Enalapril decreases plasma noradrenaline levels during the cold pressor test in human hypertensives
S. Minatoguchi, H. Ito, M. Koshiji, K. Masao, S. Hirakawa and H. Majewski
Inappropriately elevated levels of atrial natriuretic peptide may contribute to the pathophysiology of orthostatic hypotension
T. J. Tunny, R. D. Gordon, S. A. Klemm, A. W. Bachmann and W. L. Finn
Effects of repeated doses of pseudoephedrine on blood pressure and plasma catecholamines in normal subjects and in
patients with phaeochromocytoma
R. D. Gordon, D. M. Ballantine and A. W. Bachmann
Is isolated systolic hypertension a ‘white coat’ phenomenon in the elderly?
C. A. Silagy, J. J. McNeil, B. P. McGrath and S. Farish
Contents
Sample size requirements for clinical trials of isolated systolic hypertension
C. A. Silagy, J. J. McNeil and B. P. McGrath
Increase in serum total angiotension-converting enzyme activity with enalapril therapy in humans: A controlled trial
G. S. Stokes, J. C. Monaghan, J. F. Marwood, E. Obi Okoro and H. Johnston
Concurrence of primary aldosteronism and renal artery stenosis
G. S. Stokes, J. C. Monaghan, J. Roche, H. Grunstein and R. D. Gordon
Inaccuracy of electronic sphygmomanometers
S. Mann
Subpressor calcium infusion increases isovolumic left ventricular relaxation time and atrial natriuretic peptide in humans
W. L. Finn, R. D. Gordon, B. I. Seneviratne, T. J. Tunny and S. A. Klemm
Evidence for presynaptic B-adrenoceptor stimulation 24 hours after a 6 hour adrenaline infusion
A. W. Bachmann, R. D. Gordon and D. M. Ballantine
Polymorphisms of candidate genes in essential hypertension
M. J. West, K. M. Summers and P. R. Huggard
Familial hyperaldosteronism type II: Five families with a new variety of primary aldosteronism
M. Stowasser, R. D. Gordon, T. J. Tunny, S. A. Klemm, W. L. Finn and A. L. Krek
Prostaglandins and systolic blood pressure, but not angiotensin II, independently affect atrial natriuretic peptide levels in
humans
S. A. Klemm, R. D. Gordon, T. J. Tunny, W. L. Finn and A. Hornych
Population-based survey of human sodium and potassium excretion
T. C. Beard, R. Eickhoff, Z. A. Mejglo, M. Jones, S. A. Bennett and T. Dwyer
Effects of argininosuccinic acid on nitric oxide-mediated relaxations in rat aorta and anococcygeus muscle
M. J. Rand and C. G. Li
Axonal projections from respiratory centres towards the rostral ventrolateral medulla in the rat
P. Pilowsky, B. Wakefield, J. Minson, I. Llewellyn-Smith and J. Chalmers
Haemodynamic changes in the Moncada model of atherosclerosis
A. C. Yong, G. Townley and G. W. Boyd
Mesenteric vascular angiotensin-converting enzyme is increased in experimental diabetes mellitus
K. Jandeleit, J. Rumble, B. Jackson and M. E. Cooper
Mesenteric resistance and brain microvascular angiotensin-converting enzyme in the spontaneously hypertensive rat
K. Jandeleit, R. Perich, B. Jackson and C. I. Johnston
Variation in angiotensin-converting enzyme inhibitor affinity at two binding sites on rat pulmonary ACE: Influence on
bradykinin hydrolysis
R. B. Perich, B. Jackson and C. I. Johnston
Polymerase chain reaction-based DNA fingerprinting in the spontaneously hypertensive rat: Potential source of cDNA
library probes
R. Di Nicolantonio, T. Imai, K. Ikeda, M. Sawamura, Y. Yamori and K. Murakami
Development and validation of echocardiographic methods for estimating left ventricular mass in rats
E. F. Jones, S. B. Harrap, P. Calafiore and A. M. Tonkin
The heterogeneity of 118-hydroxysteroid dehydrogenase activities in the rat hippocampus implies a complex regulation of
steroid hormone action
R. E. Smith, W. R. Mercer, P. H. Provencher, V. Obeyesekere and Z. S. Krozowski
DA-1! receptors mediate renal effects of the dopamine prodrug, gludopa, in conscious rabbits
Z-Q. Wang, D. Way, L. Trigg and B. P. McGrath
Effect of enalapril on body sodium and handling of a sodium chloride load in hypertensive and normotensive rats
J. M. Ledingham and F. O. Simpson
Renal vasoconstriction is modulated by nitric oxide
J. J. Reid and M. J. Rand
Effect of neutral endopeptidase inhibitor in rats with congestive heart failure
Y. Murohara and C. I. Johnston
Interaction between vasopressin and endothelin in renal papillary tubules: Uncoupling following cell isolation and culture
E. A. Woodcock and S. Land
Isolation of adult cardiomyocytes initiates a return of inositol trisphosphate phosphorylating activity
E. A. Woodcock and K. Anderson
Long-term angiotensin II antagonism in spontaneously hypertensive rats: Effects on blood pressure and cardiovascular
amplifiers
C. J. Oddie, R. J. Dilley and A. Bobik
Differential regulation by transforming growth factor-f, of platelet-derived growth factor-simulated proliferation of vascular
smooth muscle cells from SHR and WKY rats
J. Saltis, A. Agrotis and A. Bobik
Contents
NUMBER 6, JUNE
Endothelium-dependent and -independent relaxation by dopamine in the rabbit pulmonary artery
M. Yamauchi, Y. Kobayashi, K. Shimoura, K. Hattori and A. Nakase
Ranitidine inhibits adrenergic transmission in the rat isolated anococcygeus muscle
M. C. E. Gwee and L. S. Cheah
Neurovascular function during pregnancy in the spontaneously hypertensive rat
E. M. Yong, M. T. Mano and R. J. Head
Cardiac effects of local angiotensin-converting enzyme inhibition in hypertensive patients
Y. Nakashima, T. Nii, E. Tashiro, M. Ikeda and K. Arakawa
Comparison of parathyroid hormone and calcitonin on rat renal calcium and magnesium transport
S. L. Carney
Captopril magnifies the increase in angiotensin I-converting enzyme in rats with aminonucleoside nephrosis
J. Pedraza-Chaverri, A. H. Maciel, C. Cruz and J. C. Pena
Bronchodilator activity and pharmacokinetics of new xanthines in guinea-pigs
K. Takagi, T. Hasegawa, M. Nadai, R. Sakai and K. Miyamoto
Modelling of frequency-dependent effects of lignocaine homologues on the maximum upstroke velocity of action potentials
in guinea-pig papillary muscles
T. Hamamoto, M. Ichiyama, Y. Takahashi and T. Ban
Letter to the Editor
Erratum
NUMBER 7, JULY
Influence of workload on the antihypertensive effect of exercise
M. Matsusaki, M. Ikeda, E. Tashiro, M. Koga, S. Miura, M. Ideishi, H. Tanaka, M. Shindo and K. Arakawa
A comparison of guanfacine, bunazosin, atenolol and nadolol on blood pressure and plasma noradrenaline responses to cold
pressor testing
M. Koshiji, H. Ito, S. Minatoguchi, H. Watanabe, Y. Imai, M. Kakami and S. Hirakawa
Effects of acute superior cervical ganglionectomy on cerebral blood flow and metabolism in stroke-prone spontaneously
hypertensive rats subjected to cerebral ischaemia
T. Nagao, S. Sadoshima, T. Ishitsuka, K. Kusuda, O. Shiokawa, S. Ibayashi and M. Fujishima
The effect of ovine prolactin on the epididymal sialic acid concentration in male rats
R. Gautam and B. M. J. Pereira
The effect of graded haemorrhage on erythropoietin production in the immature ovine foetus
K. M. Moritz and E. M. Wintour
Platelet-activating factor in bronchoalveolar lavage fluid of patients with adult respiratory distress syndrome
K. Matsumoto, F. Taki, Y. Kondoh, H. Taniguchi and K. Takagi
Comparative effects of dopamine and dobutamine on the pulmonary haemodynamic response to hypoxia in dogs ventilated
with a hypoxic gas mixture
H. Tanaka, K. Tajimi, T. Kasai and K. Kobayashi
523 Inhibition of nitric oxide synthase specifically enhances adrenergic vasoconstriction in rabbits
Z-Y. Du, G. J. Dusting and O. L. Woodman
Short Communications
531 Presynaptic a-adrenoreceptor-mediated modulation of norepinephrine release from vascular adrenergic neurons in reduced
renal mass salt hypertensive rats
K. Tsuda, K. Kimura, H. Shima, I. Nishio and Y. Masuyama
Ageing has no effect on the volume density of hepatocytes, reticulo-endothelial cells or the extracellular space in livers of
female Sprague-Dawley rats
G. Martin, R. B. Sewell, N. D. Yeomans and R. A. Smallwood
NUMBER 6, AUGUST
Nerve growth factor mRNA content parallels altered sympathetic innervation in the spontaneously hypertensive rat
P. H. Falckh, L. A. Harkin and R. J. Head
Circulating angiotensin II levels under repeated administration of lisinopril in normal subjects
M. Kawamura, M. Imanishi, Y. Matsushima, K. Ito and K. Hiramori
Contents
Interaction of the non-steroidal anti-inflammatory drug flufenamic acid with gastric acid secretion and H*/K*-ATPase
W. Beil, C. Greite and K-F. Sewing
Plasma adenosine concentrations are elevated in conscious spontaneously hypertensive rats
K. Yamada, A. Goto, M. Ishii, M. Yoshioka, H. Matsuoka and T. Sugimoto
Effects of chronic administration of antihypertensive drugs on vasodilation mediated by calcitonin gene-related peptide-
containing vasodilator nerves in spontaneously hypertensive rats
H. Kawasaki
575 Effects of arginine vasopressin, angiotensin II and endothelin-1 on the release of brain natriuretic peptide in vivo and in vitro
T. Horio, M. Kohno and T. Takeda
583 Dietary NS-nitro-L-arginine induces sustained hypertension in normotensive Wistar-Kyoto rats
K. Ikeda, O. G. Gutierrez Jr and Y. Yamori
587 Characterization of the baroreceptor heart rate reflex during development in spontaneously hypertensive rats
G. A. Head and M. A. Adams
Short Communication
599 Xanthines inhibit human platelet aggregation induced by platelet-activating factor
N. L. A. Misso and P. J. Thompson
NUMBER 9, SEPTEMBER
A study of serum prolactin levels in schizophrenia: Comparison of males and females
A. Kuruvilla, J. Peedicayil, G. Srikrishna, K. Kuruvilla and A. S. Kanagasabathy
Atrial natriuretic peptide in pregnancy: Response to oral sodium supplementation
S. A. Lowe, G. J. Macdonald and M. A. Brown
Studies on the effect of dopamine on the human platelet response
G. Anfossi, P. Massucco, E. Mularoni, F. Cavalot, S. Burzacca, L. Mattiello and M. Trovati
L-Arginine infusion induces hypotension and diuresis/ natriuresis with concomitant increased urinary excretion of nitrate/
nitrite and cyclic GMP in humans
K. Kanno, Y. Hirata, T. Emori, K. Ohta, S. Eguchi, T. Imai and F. Marumo
Responsiveness and sensitivity to cholinergic agonists and antagonists in bovine isolated bronchial muscle
M. G. Matera, M. Cazzolo, M. Constantino, D. De Santis and F. Rossi
Prejunctional actions of tacrine on autonomic neuroeffector transmission in rabbit isolated pulmonary artery and rat isolated
atria
M. E. Fabiani, P. Kabo and D. F. Story
Intracoronary PGE and veratrine inhibits renin release in conscious dogs via chemosensitive ventricular afferents
A. J. Gorman. J-S. Chen, S. Foster, R. G. Snyder and S. G. lams
Communications
Does the haemodynamic response to acute central hypovolaemia depend on the rate of fall of cardiac output?
R. G. Evans, I. P. Hayes and J. Ludbrook
Enhancement by endothelin-1 of the release of catecholamines from the canine adrenal gland in response to splanchnic nerve
stimulation
A. Takeuchi, T. Kimura and S. Satoh
NUMBER 10, OCTOBER
Origin of urinary epidermal growth factor in humans: Excretion of endogenous EGF and infused ['3'I]-human EGF and
kidney histochemistry
A. Lev-Ran, D. L. Hwang, J. Ben-Ezra and L. E. Williams
Inhibition of NO synthesis has an additive effect on hypertension induced by ACTH in conscious rats
M. Li, G. J. Dusting and J. A. Whitworth
Endothelin-3-induced microvascular incompetence and mitochondrial damage in rat myocardium
L. Maxwell, K. Pratt and J. Gavin
Arachidonic acid metabolism in nicotine-treated rats and nicotine-incubated rabbit aortic smooth muscle cells
S-C. G. Hui, Z. Wang, H. Zhang and C. W. Ogle
Angiotensin-converting enzyme inhibition causes deterioration in renal function in one-kidney Goldblatt hypertensive rats
with and without renal arterial stenosis
W-C. Huang, J-N. Wu and J-S. Jin
Contents
Response of plasma renin-angiotensin system to a single captopril administration in patients receiving long-term treatment
with captopril
T. Iwata, Y. Dazai, Y. Kitami, S. Muneta, Y. Imamura, E. Murakami and K. Hiwada
In vivo and in vitro effects of atrial natriuretic peptide on renin release
T. Ishimitsu, Y. Hirata, H. Matsuoka, M. Ishii, T. Sugimoto, K. Kangawa and H. Matsuo
Mechanism and prevention of chronic colonic inflammation with trinitrobenzene sulfonic acid in rats
H. Hoshino, S. Sugiyama, A. Ohara, H. Goto, Y. Tsukamoto and T. Ozawa
Different biventricular remodelling of myosin and collagen in pulmonary hypertension
S. Ishikawa, M. Honda, S. Yamada, Y. Goto, S. Morioka, Y. Ishinaga, Y. Murakami, S. Masumara and K. Moriyama
NUMBER 11, NOVEMBER
Review
Bradycardia during reversible hypovolaemic shock: Associated neural reflex mechanisms and clinical implications
N. H. Secher, J. Jacobsen, D. B. Friedman and S. Matzen
Afferent control of vasopressin and renin release during haemorrhage in normal and autonomically blocked rats
C-A. Courneya, P. I. Korner, J. R. Oliver and R. L. Woods
Cardiac B-adrenoreceptor changes in experimental hyperthyroidism in dogs
A. Hoey, L. Brown, C. Marchant, R. Atwell and C. Sernia
Arterial baroreflex control of heart period is not related to blood pressure variability in conscious hypertensive and normo-
tensive rats
D-F. Su, C. Cerutti, C. Barres, C. Julien, M. Vincent, C. Paultre and J. Sassard
Effects of 4 weeks endurance training on cardiac left ventricular structure and function
A. M. Dart, I. T. Meredith and G. L. Jennings
Epithelial disruption by proteases augments the responsiveness of porcine bronchial segments
T. I. Omari and M. P. Sparrow
NUMBER 12, DECEMBER
Potassium accelerates urinary sodium excretion during salt loading without stimulating atrial natriuretic polypeptide
secretion
M. Mano, A. Sugawara, Y. Nara, K. Nakao, R. Horie, J. Endo, H. Imura and Y. Yamori
Influence of cimetidine on gallamine-induced neuromuscular paralysis in rats
Y. Mishra and I. Ramzan
Direct renal effects of endothelin in chronic hypoxic spontaneously hypertensive rats
C. F. Chen, C. T. Chien and M. S. Wu
Assessing vascular reactivity of arteries in the small vessel myograph
G. A. McPherson
The role of the renal nerves in renin synthesis
Y. Zhang, T. Morgan and G. Read
Effects of noise on blood pressure and vascular reactivities
C-C. Wu, S-J. Chen and M-H. Yen
Cyclic adenosine 3’,5’-monophosphate content and bronchial smooth muscle contractility of hyper- and hypothyroid lungs
B. M. Nabishah, P. B. Morat, A. K. Alias, B. A. Kadir and B. A. K. Khalid
The effects of thyroxine treatment on slow- and fast-contracting skeletal muscle contractions of the cat and their cyclic AMP
level
Z. Merican, S. Sukumaran, V. L. Raj, M. H. Rajikin and B. A. K. Khalid
Referees
Author Index
Contents
SUPPLEMENT 19
High Blood Pressure Research Council of Australia Symposium, 1992
Cardiovascular Remodelling in Hypertension: The Role of the Renin-Angiotensin System and ACE Inhibition
The tissue renin—angiotensin system and its functional role
C. I. Johnston, L. M. Burrell, R. Perich, K. Jandeleit and B. Jackson
Acute and chronic effects of angiotensin-converting enzyme inhibitors on tissue angiotensin-converting enzyme
S. Y. Chai, R. Perich, B. Jackson, F. A. O. Mendelsohn and C. I. Johnston
Effect of perindopril on the development of atherosclerosis in the cholesterol-fed rabbit
J. H. Campbell, P. Fenessy and G. R. Campbell
A developmental genetic mechanism involving angiotensin in spontaneously hypertensive rats
S. B. Harrap
Diabetic renal microvascular disease: The role of hypertension and ACE inhibitors
M. E. Cooper, J. R. Rumble, T. Gin and T. Lim-Joon
The effect of hypertension and ACE inhibition on arterial structure and compliance
M. E. Safar and B. I. Levy
Remodelling of the vascular system in response to hypertension and drug therapy
B. I. Levy and M. E. Safar
Enhanced contraction to noradrenaline, serotonin and nerve stimulation but normal endothelium-derived relaxing factor
response in skin small arteries in human primary hypertension
J. A. Angus, G. L. Jennings and K. Sudhir
The clinical pharmacology of ACE inhibitors: Evidence for clinically relevant differences?
K. R. Lees, I. B. Squire and J. L. Reid
Comparison of the pharmacokinetics and pharmacodynamics of perindopril, cilazapril and enalapril
W. J. Louis, E. L. Conway, H. Krum, B. Workman, O. H. Drummer, W. Lam, P. Phillips, L. G. Howes and B. Jackson
Clinical efficacy of perindopril in hypertension
T. Morgan and A. Anderson
Angiotensin-converting enzyme inhibition as first-line treatment for hypertension
H. Thurston
SUPPLEMENT 20
Proceedings of the Interdisciplinary Symposium on Gene, Nutrition and Health, 1991
Gene-environment Interactions in Cardiovascular Diseases
Genetic factors in cardiovascular diseases
Evidence for gene—environmental interactions in Utah families with hypertension, dyslipidaemia and early coronary heart
disease
R. Williams, S. C. Hunt, P. N. Hopkins, L. L. Wu, M. C. Schumacher, B. M. Stults, L. Ball, J. Ware, S. J. Hasstedt and
J-M. Lalouel
Family history study on hypertension in Japan
N. Yasuda, Y. Nara, S-i. Kojima, H. Mikami, K. Hiwada, K. Tsuda, M. Koide and Y. Yamori
Membrane fluidity as a genetic marker of hypertension
K. Tsuda, Y. Ueno, I. Nishio and Y. Masuyama
Renin gene restriction fragment length polymorphisms in a Japanese family with a high incidence of essential hypertension
T. Okura, Y. Kitami, R. Wakamiya, T. Iwata and K. Hiwada
Analysis of the apolipoprotein B3’ hypervariable region in patients with essential hypertension
K. Higashimori, J. Higaki, T. Miki, A. Kamitani, H. Mikami, Y. Kumahara and T. Ogihara
Environmental factors in cardiovascular diseases
Review Article
25 Salt and hypertension: revisited
F. O. Simpson
29 Experimental studies on cardiovascular disorders and cellular Ca handling in shell-less chick embryos
M. Koide, M. Iwase, M. Yokota and R. S. Tuan
33 Analysis of factors in hypertension: Change of membrane fluidity in the arteries of spontaneously hypertensive and
monocrotaline-injected rats
M. Takeshita, S. Yoshida, M. Miyata and H. Yoshida
The role of oxidized lipoproteins in the pathogenesis of atherosclerosis
T. Kita, M. Yokode, K. Ishii, N. Kume, Y. Nagano, H. Arai, H. Otani, Y. Ueda and S. Hara
Contents
Gene-—environment interaction in cardiovascular diseases
43 Gene-—environment interaction in hypertension, stroke and atherosclerosis in experimental models and supportive findings
from a world-wide cross-sectional epidemiological survey: A WHO-cardiac study
Y. Yamori, Y. Nara, S. Mizushima, S. Murakami, K. Ikeda, M. Sawamura, T. Nabika and R. Horie
Abnormal hAsp70 gene expression: Its potential key role in metabolic defects in hypertension
P. Hamet
The association between salt sensitivity of blood pressure and family history of hypertension
K. Murakami, S-i. Kojima, G. Kimura, T. Sanai, K. Yoshida, M. Imanishi, H. Abe, M. Kawamura, Y. Kawano, T. Ashida,
H. Yoshimi, M. Kuramochi and T. Omae
Ethnic differences in salt sensitivity: Genetic or environmental factors?
J. P. Mtabaji, Y. Moriguchi, Y. Nara, S. Mizushima, M. Mano and Y. Yamori
Quantitative analysis of the tracking of blood pressure and relative factors in childhood: Shimane Heart Study
C. Mori, K. Watanabe, N. Haneda, Y. Harada, Z. W. Zhong and T. Nishio
