Table Of ContentCLINICAL AND EXPERIMENTAL IMMUNOLOGY
CONTENTS
Vol 108 No 1 April 1997 A. Martin, E. EscupeEro & F. MAmpaso: Role of
leucocyte adhesion molecules in aminonucleoside of
puromycin (PAN)-associated interstitial nephritis
V. THon, H. EGGENBAUER, H. M. Wo tr, M. B. O. Cioru, T. PREssLer, J. P. PANDEY & N. Hoisy: The
FIscHER, J. LitzMANn, J. Lokas & M. M. Eisc: Antigen influence of allotypes on the IgG subclass response to
presentation by common variable immunodeficiency chromosomal B-lactamase of Pseudomonas aeruginosa in
(CVID) B cells and monocytes is unimpaired cystic fibrosis patients
I. KONDRATENKO, P. L. AMLotT, A. D. B. WEBSTER & P. PANTELIDIS, A. M. Soutucott, C. M. BLack &
J. FARRANT: Lack of specific antibody response in R. M. Du Bots: Up-regulation of IL-8 secretion by
common variable immunodeficiency (CVID) associated alveolar macrophages from patients with fibrosing alveo-
with failure in production of antigen-specific memory T cells litis: a subpopulation analysis
L. KAcANI, H. Storper & M. P. Diericu: Role of IL-15 H. J. MitBurRN, L. W. Poutter, A. Di-tMec, G. M.
in HIV-1-associated hypergammaglobulinaemia CocHRANE & D. M. KeEMENy: Corticosteroids restore
N. KOLBUS, U. FLEISCHER, M. MADER, the balance between locally produced Thl and Th2
K. FELGENHAUER & W. Beucue: Detection of T cells cytokines and immunoglobulin isotypes to normal in
reactive to intestinal alkaline phosphatase, an autoanti- sarcoid lung
gen in acute bacterial infections, and discrimination D. H. BeezHo.tp, D. A. KostyaL & G. L. SUSSMAN:
between autoantigen-specific CD5" and CDS Bc ells IgE epitope analysis of the hevein preprotein; a major
W. W. Maw, T. SHimizu, K. SAto & H. ToMioka: iatex allergen
Further study on the roles of the effector molecules of T. Hipveci, L. BeErrReENs, L. VARGA, F. MARANON,
immunosuppressive macrophages induced by mycobac- B. ScumMipT, M. KiIRSCHFINK & G. FUst: Comparative
terial infection in expression of their suppressor function study of the complement-activating and specific IgE-
against mitogen-stimulated T cell proliferation binding properties of ragweed pollen allergen
S. Worku, A. BIORKMAN, M. TROYE-BLOMBERG, A. DAHLMAN-HOGLUND, L. A. HANSON &S. AHLSTEDT:
L. JEMANEH, A. FARNERT & B. CHRISTENSSON: Lym- Induction of oral tolerance with effects on numbers of IgE-
phocyte activation and subset redistribution in the per- carrying mast cells and on bystander suppression in young
ipheral blood in acute malaria illness: distinct 76° T cell rats
patterns in Plasmodium falciparum and P. vivax infections S. KAkuMu, A. OKUMURA, T. ISHIKAWA, K. Iwata,
R. GIACOMELLI, P. CipRIANI, R. LATTANZIO, M. YANo & K. YosHIOKA: Production of interleu-
M. Di FRANCO, M. LOCANTO, I. PARZANESE, A. kins 10 and 12 by peripheral blood mononuclear
PASSACANTANDO, A. Ciocct & G. Tonietti: Circulat- cells (PBMC) in chronic hepatitis C virus (HCV)
ing levels of soluble CD30 are increased in patients with infection
systemic sclerosis (SSc) and correlate with serological and C. A. ScHIRREN, M.-C. JuNG, R. ZACHOVAL,
clinical features of the disease H. Diepo_perR, R. HOFFMANN, G. RIETHMULLER &
L. Arrors & A. K. Lervert: Enrichment of antibodies G. R. Pape: Analysis of T cell activation pathways in
against phospholipids in circulating immune complexes patients with liver cirrhosis, impaired delayed hypersen-
(CIC) in the anti-phospholipid syndrome (APLS) sitivity and other T cell-dependent functions
Y.-C. CHEN, Y.-L. Ye & B.-L. CHIANG: Establishment N. M. BHat, M. M. Bieber, F. J. Hsu, C. J.
and characterization of cloned CD4 CD8 af-T cell CHAPMAN, M. SPELLERBERG, F. K. STEVENSON &
receptor (TCR)-bearing autoreactive T cells from auto- N. N. H. TENG: Rapid cytotoxicity of human B lympho-
immune NZB x NZW F, mice cytes induced by VH4-34(VH4.21) gene-encoded mono-
D. A. Troyer, B. CHANDRASEKAR, J. L. BARNES & clonal antibodies, I]
G. FERNANDES: Calorie restriction decreases platelet- K. AIzAWA, T. HAMANO, T. IWASAKI & E. KAKISHITA:
derived growth factor(PDGF)-A and thrombin receptor Down-regulatory role of surface CD4 molecules on
mRNA expression in autoimmune murine lupus nephritis autoreactive helper T cells during B cell activation
M. StepKkowskl, L. TIAN, K. L. NAPOLI, R. GHOBRIAL, M. SEGELMARK, B. PeERSSON, T. HELLMARK &
M. E. Wana, T. C. CHou & B. D. KAHAN: Synergistic J. WIESLANDER: Binding and inhibition of myeloperoxi-
mechanisms by which sirolimus and cyclosporin inhibit dase (MPO): a major function of ceruloplasmin?
rat heart and kidney allograft rejection P. Vapas, B. Grourx, E. STEFANSKI, M. WLOCH,
Z. Jun, P. A. Hitt, H. Y. LAN, R. Foti, W. Mu, R. C. W. PRUZANSKI, J. SCHROEDER & J. GAULDIE: Coordi-
Atkins & D. J. NIKOLIC-PATERSON: CD44 and nate expression of group II phospholipase A, and the
hyaluronan expression in the development of experimen- acute-phase proteins haptoglobin (HP) and aq,-anti-
tal crescentic glomerulonephritis chymotrysin (ACH) by HepG?2 cells
iV Contents
Vol 108 No 2 May 1997 S. BaizeE, G. WAHL, P. T. SoposLay, T. G. EGWANG &
A. J. GeorGes: T helper responsiveness in human Loa
U. KisHore, R. D. SoONTHEIMER, K. N. Sastry, E. G. loa infection; defective specific proliferation and cytokine
Zappi, G. R. V. HUGHES, M. A. KHAMASHTA, K. B. M. production by CD4° T cells from microfilaraemic sub-
Reip & P. EGGLETON: The systemic lupus erythematosus jects compared with amicrofilaraemics
(SLE) disease autoantigen—calreticulin can inhibit Clq S. Picot, A. NKWELLE AKEDE, J.-F. CHAULET,
association with immune complexes E. TETANYE, P. RINGWALD, J.-M. PREvosto,C . BOUDIN
A. G. TziouFAs, E. YIANNAKI, M. SAKARELLOS & P. AMBROISE-THOMAS: Chloroquine self-treatment
pAitsiotis, J. G. Routsias, C. SAKARELLOS & H. M. and clinical outcome of cerebral malaria in children
MoutsopouLos: Fine specificity of autoantibodies to S. Fuyu, K. ONo, S. SHiGETA, T. Jyo & U. YAMASHITA:
La/SSB: epitope mapping and characterization Human T cell responses to recombinant mite antigens of
K. Miacita, K. EGucui, Y. INCHINOSE, Y. KAWABE, Dermatophagoides farinae
T. TsuKADA, T. AoyaGci & S. NAGATAKI: Effects of K. KaTAGiri, S. ITAMI, Y. HATANO & S. TAKAYASU:
rapamycin on apoptosis of rheumatoid synovial cells Increased levels of IL-13 mRNA, but not IL-4 mRNA,
S. KANEKO, N. Suzuk1, N. YAMASHITA, N. NAGAFUCHI, are found in vivo in peripheral blood mononuclear cells
T. NaAKAsiMA, S. WAKISAKA, S. YAMAMOTO & (PBMC) of patients with atopic dermatitis (AD)
T. SAKANE: Characterization of T cells specific for an Y. YANAGIHARA, K. KAJIWARA, Y._ BASAKI,
epitope of human60-kD heat shock protein (hsp) in K. IkiIzAwA, K. AKIYAMA & H. Saito: Induction of
patients with Beh¢et’s disease (BD) in Japan human IgE synthesis in B cells by a basophilic cell line,
H.-O. Ito, T. So, T. UEDA, T. IMoto & T. KoGa: KU812
Prevention of collagen-induced arthritis (CIA) by treat- N. Katou, S. HirANo, S. KisHimMoto & H. YASuNo:
ment with polyethylene glycol-conjugated type II col- Calcium channel blockers suppress the contact hyper-
lagen; distinct tolerogenic property of the conjugated sensitivity reaction (CHR) by inhibiting antigen
collagen from the native one transport and presentation by epidermal Langerhans
M. Macanovic & P. J. LACHMANN: Measurement of cells in mice
deoxyribonuclease I (DNase) in the serum and urine of A. Pappa, V. CALDER, P. FeELLs & S. LIGHTMAN:
systemic lupus erythematosus (SLE)-prone NZB/NZW Adhesion molecule expression in vivo on extraocular mus-
mice by a new radial enzyme diffusion assay cles (EOM) in thyroid-associated ophthalmopathy (TAO)
J. GeorGce, M. BLANK, M. Hosnik, E. BAR-MEIR, J.-O. SANDBERG, D. L. Eizirik & S. SANDLER: IL-1]
T. Koike, E. Matsuura, M. LorBer, M. AviIRAM & receptor antagonist inhibits recurrence of disease after
Y. SHOENFELD: Oxidized low-density lipoprotein (Ox- syngeneic pancreatic islet transplantation to sponta-
LDL) but not LDL aggravates the manifestations of neously diabetic non-obese diabetic (NOD) mice
experimental antiphospholipid syndrome (APS) K. MryaAzAkI, N. M. IsBeL_, H. Y. LAN, M. HatTTor1,
P. A. JOHNSON, H. D. ALEXANDER, S. A. MCMILLAN & K. Iro, M. BAcHER, R. BUCALA, R. C. ATKINS & D. J.
A. P. MAxweELL: Up-regulation of the endothelial cell NIKOLIC-PATERSON: Up-regulation of macrophage
adhesion molecule intercellular adhesion molecule- colony-stimulating factor (M-CSF) and migration in-
1(ICAM-1) by autoantibodies in autoimmune vasculitis hibitory factor (MIF) expression and monocyte recruit-
J. H. Kim, J. E. Lovecanp, K. V. Sitz, S. RATtTOo KIM, ment during lipid-induced glomerular injury in the
R. J. MCLINDEN, K. TeNcER, K. Davis, D. S. BURKE, exogenous hypercholesterolaemic (ExHC) rat
R. N. Boswet_, R. R. Reprietp & D. L. Birx: C. J. Kootstra, D. M. VAN DER GIEZEN, J. H. J.
Expansion of restricted cellular immune responses to M. VAN KRIEKEN, E. DE HEER & J. A. BRUIJJIN:
HIV-1 envelope by vaccination: IL-7 and IL-12 differen- Effective treatment of experimental lupus nephritis by
tially augment cellular proliferative responses to HIV-1] combined administration of anti-CD1la and anti-CD54
G. PizzoLo, F. VINANTE, G. NADALI, M. KRAMPERA, antibodies
L. MorosatTo, M. CuiLosi, R. RAITERI & A. SINICCO: M. BLANK, D. B. CinEs, G. AREPALLY, A. ELpbor, A.
High serum level of soluble CD30 in acute primary HIV-1 AFEK & Y. SHOENFELD: Pathogenicity of human anti-
infection platelet factor 4 (PF4)/heparin in vivo: generation of
T. Suzuki, H. Tai, H. Yosuie, D. JEANNEL, S. mouse anti-PF4/heparin and induction of thrombocyto-
FOURNIER, B. Dupont, G. De THE & K. Hara: penia by heparin
Characterization of HIV-related periodontitis in AIDS N. SHINTANI, T. NAKAJIMA, H. NAKAKUuBO, H. NAGAI,
patients: HIV-infected macrophage exudate in gingival Y. KAGITANI, H. TAKIZAWA & H. Asakura: Intrave-
crevicular fluid as a hallmark of distinctive etiology nous immunoglobulin ([VIG) treatment of experimental
M. Kawano, S. Tsunopa, I. Koni, H. MAsBucui, H. colitis induced by dextran sulfate sodium in rats
Muramorto, A. YACHIE & H. Sekt: Decreased expres- B. CHANDRASEKAR, J. T. COLSTON & G. L. FREEMAN:
sion of 20-kD homologous restriction factor (HRF20, Induction of proinflammatory cytokine and antioxidant
CD59) on T lymphocytes in Epstein—Barr virus (EBV)- enzyme gene expression following brief myocardial-
induced infectious mononucleosis ischaemia
M. Ito, M. WaTANABE, T. IHARA, H. KAMIYA & A. HomBAcH, T. TILLMANN, M. JENSEN, C. HEUSER,
M. SAKURAI: Measles virus induces apoptotic cell R. Sircar, V. DiEHL, W. Kruis & C. POHL: Specific
death in lymphocytes activated with phorbol 12-myri- activation of resting T cells against tumour cells by
state 13-acetate (PMA) plus calcium ionophore bispecific antibodies and CD28-mediated costimulation
Contents
is accompanied by Th! differentiation and recruitment of mRNA for IL-4 in the Brown Norway rat: support for
MHC-independent cytotoxicity a role for Th2 cell activity
R. Lorp, S. Goto, F. Vari, C. EDWARDS-SMITH, S. TAKESHITA, H. DoBAsnui, K. NAKATANI, Y. KOIKE,
S. CH1BA, M. SUNAGAWA & S. V. LyNcu: Differences H. Tsusimoto, K. HirRayAMA, Y. KAWAMURA,
in the rate of donor leucocyte migration between K. Mort, I. SEKINE & S. YosH10Ka: Circulating soluble
natural and drug-assisted tolerance following rat liver selectins in Kawasaki disease
transplantation K. TsuBoKURA, E. BERNDTSON, A. BOGSTEDT,
J. Ripincs, I. C. NicHo_tson, W. Gotpswortuy, B. KAisseR, M. Kim, M. Ozeki & L. HAMMARSTROM:
R. HAstaM, D. M. RoBerton & H. ZoLa: Somatic Oral administration of antibodies as prophylaxis and
hypermutation of immunoglobulin genes in human therapy in Campylobacter jejuni-infected chickens
neonates H. X10NG, S. Ouya, Y. TANABE & M. MITSUYAMA:
F. A. Houssiau, F. MASCART-LEMONE, M. STEVENS, Persistent production of interferon-gamma (IFN-7y) and
M. LisBin, J.-P. DEVOGELAER, M. GOLDMAN & J.-C. IL-12 is essential for the generation of protective
RENAULD: IL-12 inhibits in vitro immunoglobulin pro- immunity against Listeria monocytogenes
duction by human lupus peripheral blood mononuclear J. D. M. CampBeELt, D. J. Brown, A. K. NICHANI,
cells (PBMC) S. E. M. Howie, R. L. SPOONER & E. J. GLAss: A non-
protective T helper 1 response against the intra-
macrophage protozoan Theileria annulata
M. G. SALMon, J. B. DE souza, G. A. BUTCHER &
Vol 108 No 3 June 1997 J. H. L. PLAYFAiR: Premature removal of uninfected
erythrocytes during malarial infection of normal and
K. CHOUDHURI, G. MIELI-VERGANI & D. VERGANI: immunodeficient mice
Cytochrome P4502D6: understanding an autoantigen M. L. JoHNson, L. G. KEETON, Z.-B. ZHu, J. E.
Z. X. Liu, S. SUGAWARA, N. HiwaTasuHi, M. NoGucul, VoLANAKIS, M. D. Cooper & H. W. SCHROEDER:
H. RiktisHi, K. KUMAGAI & T. Toyota: Accessory cell Age-related changes in serum immunoglobulins in
function ofa human colonic epithelial cell line HT-29 for patients with familial IgA deficiency and common vari-
bacterial superantigens able immunodeficiency (CVID)
E. G. DE LA CONCHA, M. FERNANDEZ-ARQUERO, C. PIGNATA, M. Fiore, I. Scotese, E. CosENTINI,
S. SANTA-CRUZ, G. LopEz-NAvA, M. A. FIGUEREDO, M. P. SPERANDEO, C. Turco, A. PETRELLA, L.
M. Diaz-RuBio & J. GARCIA-PAREDES: Positive and NOTARANGELO & S. VENUTA: Combined immuno-
negative associations of distinct HLA-DR2 subtypes deficiency phenotype associated with inappropriate
with ulcerative colitis (UC) spontaneous and activation-induced apoptosis
A. M. YAMAMOTO, C. JOHANET, J.-C. DUCLOS-VALLEE, K.SANDSTEDT, A. BERGLOF, R. FEINSTEIN, G. BOLSKE,
F. A. BusTARRET, F. ALVAREZ, J.-C. HOMBERG & J.-F B. EvENGARD & C. I. E. Smitu: Differential suscept-
BAcH: A new approach to cytochrome CYP2D6 anti- ibility to Mycoplasma pulmonis intranasal infection in
body detection in autoimmune hepatitis type-2 (AIH-2) X-linked immunodeficient (xid), severe combined
and chronic hepatitis C virus (HCV) infection: a sensitive immunodeficient (scid), and immunocompetent mice
and quantitative radioligand assay A. E. PLATonov, G. A. SHIPULIN, O. JU. SHIPULINA,
J. C. W. Epwarops, S. BLADEs & G. CAMBRIDGE: I. V. VERSHININA & P. DENSEN: Heterozygous C8B
Restricted expression of FceyRIII (CD16) in synovium complement deficiency does not predispose to meningo-
and dermis: implications for tissue targeting in rheuma- coccal disease
toid arthritis (RA) M. J. Hopart, B. A. FERNIE, R. WURZNER, R. G.
J. C. W. Epwarops, R. D. LEIGH & G. CAMBRIDGE: O_proyp, R. A. Harrison, V. Joysey & P. J. LAcH
Expression of molecules involved in B lymphocyte survi- MANN: Difficulties in the ascertainment of C9 deficiency:
val and differentiation by synovial fibroblasts lessons to be drawn from a compound heterozygote C9-
U. NyMANn, A. MUsseEner, E. LArRsson, J. LORENTZEN deficient subject
& L. KLARESKOG: Amelioration of collagen I-induced C. Pomeroy, J. MITCHELL, E. ECKERT, N. RAYMOND,
arthritis in rats by the type IV phosphodiesterase inhibi- R. Crossy & A. P. DALMAsso: Effect of body weight and
tor Rolipram caloric restriction on serum complement proteins, includ-
D. VAZQUEZ-ABAD, L. TIAN, M. ZANETTI & N. F. ing Factor D/adipsin: studies in anorexia nervosa and
ROTHFIELD: A cross-reactive idiotype in scleroderma obesity
A. HAuscCHILD, H. KRogEGER, N. A. MITCHISON, C. EkerFELT, J. ERNERUDH & M. VReETHEM: ThI-like
S. UGrinovic & K. ZWINGENBERGER: Thalidomide responses to peptides from peripheral nerve myelin
therapy of established collagen-induced arthritis (CIA) proteins in patients with polyneuropathy associated
not accompanied by an evident Th2 shift with monoclonal gammopathy
H. M. Burt & J. K. Jackson: The priming action of F. D. Sui, G.-X. ZHANG, X.-F. Bal, P.-H. VAN DER
tumour necrosis factor-alpha (TNF-a) and granulo- MEIDE & H. Link: Cellular mRNA expression of inter-
cyte-macrophage colony-stimulating factor (GM-CSF) feron-gamma (IFN-y), IL-4 and IL-10 relates to resis-
on neutrophils activated by inflammatory microcrystals tance to experimental autoimmune myasthenia gravis
F. J. Qasim, S. THiru & K. GILLEspiE: Gold and (EAMG) in young Lewis rats
D-penicillamine induce vasculitis and up-regulate T. HosHino, R. Suzuki, Y. TsuRuTA, T. MATSUTANI,
V1 Contents
M. Kikucuwi, M. KAwamoto, R. GOUHARA, B. Lacier, B. Lepec, J. Bousquet & J. PENE: Different
T. SHiRAISHI, M. Mocuizuk!i, K. Irou & K. O1zuUMI: modulation by histamine of IL-4 and interferon-gamma
Non-restricted T cell receptor (TCR)-Va and -VB gene (IFN-7y) release according to the phenotype of human
usage in patients with pulmonary sarcoidosis ThO, Th! and Th2 clones
B. L. SHiRKEY, S. SLAVIN, B. P. Vistica, M. J. PoDGOR N. SHARFE, H. K. Dapb1, J.J. OSHEA & C. M. ROIFMAN:
& I. Gery: Immunomodulatory effects of linomide Jak3 activation in human lymphocyte precursor cells
in animals immunized with immunopathogenic retinal L. A. FERNANDEZ, R. CHENG, I. SADEK, T. J. NEVILL &
antigens: dissociation between different immune func- J. M. MAcsween: Normal CD5”* B lymphocytes are
tions poor stimulators in the autologous mixed lymphocyte
reaction (AMLR)
