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About CHE503 Bioreactor Scale Up
This document discusses scale-up of stirred tank bioreactors. It explains that scaling up requires maintaining similarity in process and phenomena, though operating parameters cannot always be linearly scaled. It provides examples of scaling up agitation and gassing parameters like power input per volume, tip speed, mixing time, and superficial gas velocity. Maintaining these parameters constant can require changing the agitation rate between scales. The document cautions that scale-up requires empirical evaluation and there are no set rules. It provides an illustrative problem calculating dimensions and agitation rates between scales to maintain constant parameters.
Detailed Information
| Author: | ['Plant Design'] |
|---|---|
| Publication Year: | 2019 |
| Pages: | 18 |
| Language: | English |
| Format: | |
| Price: | FREE |
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