Cellular and molecular biology of sodium transport

395 Pages·1989·18.731 MB·xiii, 379 p. : ill\395

by  Stanley G Schultz

Current Topics
in Membranes and Transport
VOLUME 34
Cellular and Molecular Biology of
Sodium Transport
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C u r re nt To pics
in Membranes and Transport
Edited by
Joseph F. Hoffman Gerhard Giebisch
Department of Cellular and Molecular Physiology Department of Cellulor and Molecular Physiology
Yale University School of Medicine Yale University School of Medicine
New Haven, Connecticut New Haven, Connecticut
VOLUME 34
Cellular and Molecular Biology of Sodium Transport
Guest Editor
Stanley G. Schultz
Department of Physiology and Cell Biology
The University of Texas Medical School
Houston, Texas
Volume 34 is part of the series from the Yale Department of Cellular and Molecular Physiology
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Cont ents
Preface, xi
Yale Membrane Transport Processes Volumes, xiii
CHAPTER 1. Physical State of Cell Sodium
MORTIMER M. CIVAN AND MORDECHAI SHPORER
I. Introduction, 1
11. Relationship of Average Concentration to Cytosolic Activity of
Cell Sodium Ions, 2
111. Summary, 15
References. 16
CHAPTER 2. lntracellular Sodium Activities and Basolateral Membrane Potassium
Conductances of Sodium-Absorbing Epithelial Cells
STANLEY G. SCHULTZ
I. Introduction, 21
11. Chronic Stimulation of Sodium Absorption by Hyperaldosteronism, 24
111. Rapid Stimulation of Transcellular Sodium Absorption, 27
IV. Conclusions and Speculations, 35
V. Summary, 40
References, 40
CHAPTER 3. Feedback Regulation of Epithelial Sodium Channels
LAWRENCE G. PALMER, GUSTAVO FRINDT,
RAND1 B. SILVER. AND JON STRIETER
I. Introduction, 45
11. Observations of Feedback Control, 47
111. Possible Mediators of Feedback Control, 52
IV. Conclusions, 57
References, 59
V
vi CONTENTS
CHAPTER 4. Electron Microprobe Analysis of Cell Sodium in Epithelia
ROGER RICK
I. Electron Microprobe Analysis, 61
11. State and Distribution of Intracellular Ions, 64
111. Analysis of Epithelial Ion Transport, 67
References, 80
CHAPTER 5. Sodium Dependence of Cation Permeabilities and Transport
SIMON A. LEWIS AND PAUL J. DONALDSON
I. Introduction, 83
11. Evidence for Membrane Transport Regulation, 85
111. Examples of Membrane Transport Regulation: Cross-Talk, 86
I v. Possible Signal for Regulation of Membrane Properties, 87
V. Transport and Cell Volume, 88
VI. Regulatory Mechanisms of Channels and Transporters, 90
VII. Possible Cellular Transducers, 96
VIII. Reassessment of Double-Membrane Model, 97
1x.
Uncharted Regions, 100
X. Summary, 101
References, 102
CHAPTER 6. The “Second” Sodium Pump and Cell Volume
FULGENCIO PROVERBIO, REINALDO MARIN,
AND TERESA PROVERB10
I. Introduction, 105
11. Sodium Transport in Kidney Slices, 106
111. Sodium-Stimulated ATPase Activities, 109
IV. Active Sodium Uptake in Basolateral Plasma Membrane Vesicles, 111
V. Cellular Volume and ATPase Activity, 112
VI. Conclusions, 116
References, 117
CHAPTER 7. Rapid Stimulation-Associated Changes in Exocrine Na + ,K+ -ATPase
Subcellular Distribution
AUSTIN K. MIRCHEFF, MICHAEL E. BRADLEY,
SAMUEL C. YIU, AND ROSS W. LAMBERT
I. Introduction, 121
11. Role of Na+,K+-ATPase in Sodium Chloride Secretion, 122
vii
CONTENTS
111. Functional and Immunocytochemical Evidence for Cytoplasmic
Na+,K+-ATPase Pools, 124
IV. Delineation of Cytoplasmic Na+,K+-ATPase Pools, 127
V. Stimulation-Associated Recruitment of Na+,K+-ATPase to Lacrimal Acinar Cell
Basolateral Plasma Membranes, 136
References, 140
CHAPTER 8. Differential Subunit and lsoform Expression Involved in Regulation of
Sodium Pump in Skeletal Muscle
KUNIO TAKEYASU, KAREN J. RENAUD, JOSEPH
TAORMINO, BARRY A. WOLITZKY, ANDREW BARNSTEIN,
MICHAEL M. TAMKUN, AND DOUGLAS M. FAMBROUGH
I. Introduction, 143
11. Isoforms of Avian Sodium Pump a and /3 Subunits, 144
111. Analysis of Subunit Function and Regulation through Expression of Avian Sodium
Pump cDNAs in Tissue-Cultured Mouse Cells, 152
IV. Veratridine-Induced Up-Regulation of Sodium Pump
in Primary Muscle Cultures, 156
V. Regulation of Sodium Pump in Other Systems, 162
References, 163
CHAPTER 9. Transepithelial Sodium Transport and Its Control by Aldosterone:
A Molecular Approach
BERNARD C. ROSSIER, FRANCOIS VERREY, AND
JEAN-PIERRE KRAEHENBUHL
I. Introduction, 167
11. Mechanism of Action of Aldosterone: A Model, 168
111. Control of Sodium Transport by Aldosterone in Vim, 169
IV. Strategy for Cloning Sodium Pump and Sodium Channel Using Antibody
Recognizing a Shared Epitope, 173
V. Role of Sodium Channel in Early Mineralocorticoid Response, 179
VI. Role of Na+,K+-ATPase in Late Mineralocorticoid Response, 179
VII. Conclusions, 181
References, 181
CHAPTER 10. Involvement of Na +,K+-ATPase in Antinatriuretic Action
of Yineralocorticoids in Mammalian Kidney
ALAIN DOUCET AND CATHERINE BARLET-BAS
I. Introduction, 185
11. Localization of Aldosterone Receptors along the Nephron, 187
viii CONTENTS
111. Aldosterone Control of Na+,K+-ATPase Activity
in Specific Nephron Segments, 190
IV. Methodology for Studying Mechanism of Aldosterone Action on Tbbular
Na+,K +-ATPase, 194
V. Mechanism of Aldosterone Action on Na+ ,K+-ATPase
in the Collecting Tubule, 199
References, 205
CHAPTER 11. Modulation of Na ,K -ATPase Expression in Renal Collecting Duct
+ +
ROGER G. O’NEIL
I. Introduction, 209
11. Cellular Model for Sodium and Potassium Transport
in Cortical Collecting Duct, 210
111. Cellular Actions of Aldosterone, 212
IV. Modulation of Aldosterone Actions, 215
V. Cell Volume Changes as Part of Aldosterone Actions, 221
Vl. Summary, 224
References, 225
CHAPTER 12. Electrogenic Properties of the NalK Pump: Voltage Dependence and
Kinetics of Charge Translocation
H.-J. APELL, R. BORLINGHAUS, AND P. LAUGER
1. Introduction, 229
11. Fast Charge Translocations Associated with Partial Reactions
of the Na/K Pump, 230
111. Voltage Dependence of Transport Rates, 246
1V. Conclusion, 249
References. 250
CHAITER 13. Sodium Pump Current in Renal Tubular Cells
JEAN-DANIEL HORISBERGER
1. Introduction, 253
11. Methods Used to Study Pump Current in Epithelial Cells, 256
Ill. Pump Current in Collecting Tubule of Amphiuma, 261
IV. Conclusion, 264
References, 265
ix
CONTENTS
CHAPTER 14. Voltage Dependence of NalK Pump Current
DAVID C. GADSBY, ANTHONY BAHINSKI, AND
MASAKAZU NAKAO
I. Introduction, 269
11. Experimental Approach, 272
111. Steady-State Na/K Pump Current Is Strongly Voltage Dependent, 273
IV. Voltage Dependence of Outward Na/K Pump Current Is Attenuated at Low "a],, 276
V. Transient Pump Currents Are Associated with Sodium Translocation, 276
VI. Voltage-Sensitive Steps, 283
VII. Rate-Limiting Steps, 284
References, 286
CHAPTER 15. Sodium-Calcium Exchange in Cardiac, Smooth, and Skeletal Muscles:
Key to Control of Contractility
MORDECAI P. BLAUSTEIN
I. Introduction, 289
11. Na+-Ca2+ Exchange in Barnacle Muscle, 292
111. Na+-Ca2+ Exchange in Vertebrate Skeletal Muscle, 295
IV. Na+-Caz+ Exchange in Cardiac Muscle, 296
V. Na+-Ca2+ Exchange in Smooth Muscles, 304
VI. Conclusion, 320
References, 321
CHAPTER 16. Activation of Sodium-Hydrogen Exchange by Mitogens
SERGIO GRINSTEIN, JULIA D. SMITH,
STEPHEN H. BENEDICT, AND ERWIN W. GELFAND
1. Introduction, 331
11. Activation of Antiport by Mitogens and Comitogens, 332
111. Na+-H+ Exchange and Initiation of Proliferation, 334
IV. Na+-H+ Exchange and Increased Protooncogene RNA Levels, 335
V. Concluding Remarks, 340
References, 342
CHAPTER 17. Sodium Pump Regulation by Endogenous Inhibitors
GARNER T. HAUPERT, JR.
I. Background, 345
11. Hypothalamic Na+ ,K+-ATPase Inhibitor, 351
111. Discussion, 360
References, 362
Index, 367