Cell Adhesion Molecules: Implications in Neurological Diseases

423 Pages·2014·6.3 MB·English

by  Lisette Leyton Ph.D.

Advances in Neurobiology 8
Vladimir Berezin
Peter S. Walmod Editors
Cell
Adhesion
Molecules
Implications in Neurological Diseases
Advances in Neurobiology
Volume 8
Series Editor
Arne Schousboe
For further volumes:
http://www.springer.com/series/8787

Vladimir Berezin (cid:129) Peter S. Walmod
Editors
Cell Adhesion Molecules
Implications in Neurological Diseases
Editors
Vladimir Berezin Peter S. Walmod
Neuroscience and Pharmacology Neuroscience and Pharmacology
University of Copenhagen University of Copenhagen
Copenhagen, Denmark Copenhagen, Denmark
ISSN 2190-5215 ISSN 2190-5223 (electronic)
ISBN 978-1-4614-8089-1 ISBN 978-1-4614-8090-7 (eBook)
DOI 10.1007/978-1-4614-8090-7
Springer New York Heidelberg Dordrecht London
Library of Congress Control Number: 2013953878
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Contents
Part I Cell Adhesion Molecules Belonging
to the Immunoglobulin Superfamily
1 Thy-1 Modulates Neurological Cell–Cell and Cell–Matrix
Interactions Through Multiple Molecular Interactions ...................... 3
Lisette Leyton and James S. Hagood
2 The IgCAMs CAR, BT-IgSF, and CLMP:
Structure, Function, and Diseases ......................................................... 21
Jadwiga Schreiber, Hanna Langhorst, René Jüttner,
and Fritz G. Rathjen
3 GLIALCAM, A Glial Cell Adhesion Molecule
Implicated in Neurological Disease ....................................................... 47
Alejandro Barrallo-Gimeno and Raúl Estévez
4 The Neuroplastins: Multifunctional Neuronal Adhesion
Molecules—Involvement in Behaviour and Disease ............................ 61
Philip Beesley, Michaela Kraus, and Nathalie Parolaro
5 Roles of Nectins and Nectin-Like Molecules
in the Nervous System............................................................................. 91
Masahiro Mori, Yoshiyuki Rikitake, Kenji Mandai,
and Yoshimi Takai
6 ICAM-5: A Neuronal Dendritic Adhesion Molecule Involved
in Immune and Neuronal Functions ..................................................... 117
Carl G. Gahmberg, Lin Ning, and Sonja Paetau
7 ROUNDABOUT Receptors .................................................................... 133
Athéna R. Ypsilanti and Alain Chedotal
v
vi Contents
8 New Insights into the Roles of the Contactin Cell Adhesion
Molecules in Neural Development ......................................................... 165
Alma N. Mohebiany, Sheila Harroch, and Samuel Bouyain
9 The L1 Family of Cell Adhesion Molecules: A Sickening
Number of Mutations and Protein Functions ...................................... 195
Michael Hortsch, Kakanahalli Nagaraj, and Rula Mualla
10 Organisation and Control of Neuronal Connectivity
and Myelination by Cell Adhesion Molecule Neurofascin .................. 231
Julia Ebel, Simone Beuter, Jennifer Wuchter, Martin Kriebel,
and Hansjürgen Volkmer
11 Roles for DSCAM and DSCAML1 in Central Nervous
System Development and Disease .......................................................... 249
María Luz Montesinos
Part II Cell Adhesion Molecules Not Belonging
to the Immunoglobulin Superfamily
12 The Adhesion Molecule Anosmin-1 in Neurology: Kallmann
Syndrome and Beyond ............................................................................ 273
Fernando de Castro, Pedro F. Esteban, Ana Bribián,
Verónica Murcia-Belmonte, Diego García- González,
and Diego Clemente
13 Protocadherins in Neurological Diseases .............................................. 293
Takahiro Hirabayashi and Takeshi Yagi
14 Neural Cell Adhesion Molecules Belonging to the Family
of Leucine-Rich Repeat Proteins ........................................................... 315
Malene Winther and Peter S. Walmod
Index ................................................................................................................. 397
Contributors
Alejandro Barrallo-Gimeno, Ph.D. Physiology Section, Department of Physio-
logical Sciences II , School of Medicine, University of Barcelona , Barcelona , Spain
Philip Beesley, B.Sc., Ph.D. School of Biological Sciences, Royal Holloway
University of London , Egham , UK
Life Technologies, Paisley, UK
[email protected]
Vladimir Berezin, Ph.D. Laboratory of Neural Plasticity, Department of
Neuroscience and Pharmacology, Faculty of Health Sciences, University of
Copenhagen , Copenhagen , Denmark
[email protected]
Simone Beuter Department of Molecular Biology , N MI an der Universität
Tübingen , Reutlingen , Germany
Samuel Bouyain, D.Phil. Division of Molecular Biology and Biochemistry ,
School of Biological Sciences, University of Missouri-Kansas City , Kansas City ,
MO , USA
[email protected]
Ana Bribián, Ph.D. Grupo de Neurobiología del Desarrollo-GNDe, Hospital
Nacional de Parapléjicos-SESCAM, Toledo, Spain
Institute of Bioengineering of Catalonia, Parc Cientifi c de Barcelona and Cell
Biology Department , Universidad de Barcelona , Barcelona , Spain
[email protected]
Fernando de Castro, M.D., Ph.D. Grupo de Neurobiología del Desarrollo-GNDe ,
Hospital Nacional de Parapléjicos-SESCAM , Toledo , Spain
[email protected]
Alain Chedotal, Ph.D., DR1 INSERM. Institut de la Vision, INSERM UMRS
968, CNRS UMR 7210 , Paris , France
[email protected]
vii
viii Contributors
Diego Clemente, Ph.D. Grupo de Neurobiología del Desarrollo-GNDe , Hospital
Nacional de Parapléjicos-SESCAM , Toledo , Spain
[email protected]
Julia Ebel Department of Molecular Biology , NMI an der Universität Tübingen ,
Reutlingen , Germany
Pedro F. Esteban, Ph.D. Grupo de Neurobiología del Desarrollo-GNDe , Hospital
Nacional de Parapléjicos-SESCAM , Toledo , Spain
[email protected]
Raúl Estévez, Ph.D. Physiology Section, Department of Physiological Sciences
II , School of Medicine, University of Barcelona , Barcelona , Spain
[email protected]
Carl G. Gahmberg, M.D. Faculty of Bio- and Environmental Sciences, Division of
Biochemistry and Biotechnology , University of Helsinki , Helsinki , Finland
carl.gahmberg@helsinki.fi
Diego García-González, Ph.D. Grupo de Neurobiología del Desarrollo-GNDe ,
Hospital Nacional de Parapléjicos-SESCAM , Toledo , Spain
[email protected]
James S. Hagood, M.D. Division of Pediatric Respiratory Medicine, Rady
Children’s Hospital of San Diego, University of California-San Diego , La Jolla ,
CA , USA
[email protected]
Sheila Harroch, Ph.D. Department of Neuroscience , School of Biological
Sciences, Institut Pasteur de Paris , Paris, France
[email protected]
Takahiro Hirabayashi, Ph.D. KOKORO-Biology group and JST-CREST,
Laboratories for Integrated Biology , G raduate School of Frontier Biosciences,
Osaka University , Osaka , Suita, Japan
[email protected]
Michael Hortsch, Ph.D. Department of Cell and Developmental Biology ,
University of Michigan , Ann Arbor , MI, USA
[email protected]
René Jüttner Max-Delbrück-Centrum für Molekulare Medizin , Berlin , Germany
Michaela Kraus, B.Sc., Ph.D. School of Biological Sciences , Royal Holloway
University of London, Egham , UK
Martin Kriebel Department of Molecular Biology , NMI an der Universität
Tübingen , Reutlingen , Germany
Hanna Langhorst Max-Delbrück-Centrum für Molekulare Medizin , Berlin ,
Germany
Contributors ix
Lisette Leyton, Ph.D. Programa de Biología Celular y Molecular, Facultad de
Medicina, Instituto de Ciencias Biomédicas, Universidad de Chile , Santiago,
Región Metropolitana , Chile
[email protected] ; [email protected]
Kenji Mandai, M.D., Ph.D. Division of Pathogenetic Signaling , Department of
Biochemistry and Molecular Biology , K obe University Graduate School of
Medicine , Kobe, Japan
CREST, JST, Kobe, Japan
[email protected]
Alma N. Mohebiany, B.Sc., M.Sc. Department of Neuroscience , School of
Biological Sciences, Institut Pasteur de Paris , Paris , France
María Luz Montesinos, Ph.D. Departamento de Fisiología Médica y Biofísica ,
Universidad de Sevilla , Sevilla , Spain
[email protected]
Masahiro Mori, M.D., Ph.D. Division of Neurophysiology , Department of
Physiology and Cell Biology , Kobe University Graduate School of Medicine ,
Kobe, Japan
Faculty of Health Sciences, Kobe University Graduate School of Health Sciences,
Kobe, Japan
CREST, JST, Kobe, Japan
[email protected]
Rula Mualla, B.Sc. Department of Cell and Developmental Biology , University of
Michigan , Ann Arbor , MI , USA
Verónica Murcia-Belmonte, Ph.D. Grupo de Neurobiología del Desarrollo-
GNDe , Hospital Nacional de Parapléjicos-SESCAM , Toledo , Spain
[email protected]
Kakanahalli Nagaraj, Ph.D. Department of Applied Zoology , Kuvempu
University , Shimoga , India
[email protected] ; [email protected]
Lin Ning, M.Sc. Faculty of Bio- and Environmental Sciences, Division of
Biochemistry and Biotechnology , University of Helsinki , Helsinki , Finland
Sonja Paetau, B.Sc. Faculty of Bio- and Environmental Sciences, Division of
Biochemistry and Biotechnology , University of Helsinki , Helsinki , Finland
Nathalie Parolaro, B.Sc., Ph.D. School of Biological Sciences, Royal Holloway
University of London , Egham , UK
Fritz G. Rathjen Max-Delbrück-Centrum für Molekulare Medizin , Berlin ,
Germany
[email protected]