Table Of ContentCARDIOLOGY 
S 
CLINICS 
Cardiol Clin 20 (2002) 645-662 
Subject Index  to Volume  20 
Volume 20 
February  EMERGENCY CARDIOVASCULAR  CARE, pages  1-180 
May  CLINICAL  HYPERTENSION,  pages  181-340 
August  ADVANCES  IN ADULT CONGENITAL  HEART DISEASE, pages 341-490 
November  PERIPHERAL VASCULAR  DISEASE, pages 491-662 
Note: Page numbers of article titles are in boldface type 
A  therapy, 515-518 
Abdominal aortic aneurysms, endovascular  complications of, 518 
treatment of, 579-597  economic impact of choice of, 518 
early experience, 579-581  endovascular, 516 
future perspectives, 586-587  lytic, in thrombosed bypass grafts, 
indications for, 586  517-518 
problems with current endograft devices,  percutaneous aspiration thrombectomy, 
583-586  518 
endoleak, 583-585  percutaneous mechanical 
morphological and structural changes,  thrombectomy,  518 
585  surgical, 515-516 
secondary interventions after, 585-586  thrombolytic, 516-517 
with Vanguard device, 581-583 
Adrenergic agonists, 64, 65 
open surgical treatment of, 563-578 
history of, 62 
clinical suspicion, 564-565 
mechanism of action of, 63, 64 
definitions and diagnosis, 563-564 
emerging strategies for small, 568-569  Adrenergic fibers, in autonomic nervous system, 62 
imaging surveillance vs.  repair of, 566-567  Adrenergic inhibitors as antihypertensive 
open repair vs. endovascular repair, 567 
drugs, clinical pharmacology of, 267, 268, 
postoperative complications,  573-575  270, 271 
referral to a high-volume center, 569 
screening, 565  African-American Study of Kidney Disease, 308, 
serendipitous discovery of, 565-566  309 
techniques of, 569-573  African-Americans,  hypertension in, 307-309 
juxtarenal, 572-573  treatment of, 307-309 
retroperitoneal approach, 571-572 
Age, risk factor for critical limb ischemia,  536 
transabdominal approach, 569-571 
transperitoneal vs.  retroperitoneal repair,  Airway, alternative, 25 
567-568  cuffed oropharyngeal, 25 
Abdominal aortic disease, magnetic resonance  emergency management of, 23-35 
esophageal obturator, 23, 24 
angiography in diagnosis of, 507-508 
laryngeal mask, 23, 24, 27, 28 
Acute limb ischemia, approach tu patient with, 
513-520  Alagille syndrome, in tetralogy of Fallot, 
387 
history, physical, and diagnosis, 513-514 
pathophysiology, 514-515  Alcohol, and hypertension, 255, 256 
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646  Subject Index | Cardiol Clin 20 (2002) 645-662 
Aldosteronism, primary, as cause of secondary  Antiarrhythmic drugs, in advanced cardiac life 
hypertension, 284  support, 79-87 
diagnostic tests for, 284  animal studies of, 81 
therapy for, 284  basic principles of, 80 
basic science of, 80, 81 
Alpha agonists, central, as antihypertensive drugs, 
clinical studies of, 81, 82 
adverse effects of, 270 
history of, 79, 80 
clinical pharmacology of, 269, 270 
state of the evidence regarding, 84 
Alpha blockers as antihypertensive drugs, adverse  unanswered questions about, 85 
effects of, 268, 269 
Anticoagulation therapy, for carotid 
clinical pharmacology of, 268, 269 
disease, 600 
American Heart Association Chain 
Antidiuretic hormone, in normal blood pressure 
of Survival,  1 
control,  197, 198 
Amiodarone, in cardiac arrest, 81, 83, 84 
Antihypertensive drugs, clinical pharmacology of, 
Amputation, primary, due to critical limb  265-280 
ischemia, 543  in pregnancy,  306 
Anesthesia, for carotid endarterectomy, general  Antiplatelet therapy, for carotid disease, 
vs.  regional, 606-607  599-600 
to reduce intermittent claudication,  525 
Aneurysms, abdominal aortic. See Abdominal 
aortic aneurysms.  Aorta, abdominal aortic aneurysms.  See 
atrial septum, relation of to cryptogenic stroke,  Abdominal aortic aneurysms. 
361, 362 
Aortic arch, magnetic resonance angiography of, 
splanchnic artery, mesenteric disease due to, 
508-511 
616-620 
Aortofemoral bypass, in patients with critical limb 
Angina, unstable, glycoprotein IIb/IIIa inhibitors 
ischemia, 540 
in, 166-168 
Apnea, sleep, as cause of secondary hypertension, 
Angiogenesis, therapeutic, 639-640 
diagnostic tests for, 284 
Angiogenic growth factors, for intermittent  therapy for, 284 
claudication, 527 
Arginine, L-, for intermittent claudication, 527 
Angiography, in diagnosis of peripheral arterial 
Arms, arterial disease in. See Upper extremities, 
disease, magnetic resonance (MRA), 496, 498, 
arterial disease of. 
499, 501-512, 553-555 
x-ray digital subtraction, 498-499  Arrhythmia(s), atrial, and hemodynamics, 356-358 
atrial flutter and, 358 
Angioplasty, balloon, and stenting for upper 
atrioventricular synchrony and, 357, 358 
extremity arterial disease, 629-630 
in congenital heart disease, 457-465 
infra-popliteal, for critical limb ischemia, 
electrophysiology and RF-ablation in, 359, 
539 
360 
Angiotensin receptor blockers as antihypertensive  inappropriate heart rate and, 357 
drugs, adverse effects of, 273, 274  pacemaker therapy for, 359 
clinical pharmacology of, 273, 274  pharmacologic therapy for, 358, 359 
Angiotensin-converting enzyme inhibitors, in  role of surgery in treatment of, 360, 361 
treatment of, 358-361 
acute coronary syndromes,  151 
and ventricular rhythm irregularity, 358 
in acute ischemic syndromes,  170, 171 
cardiac, and sudden death, hypertensive, 237, 
as antihypertensive drugs, adverse effects of, 
238 
272, 273 
prevention of, 238 
clinical pharmacology of, 271-273 
Arterial disease, abdominal aortic aneurysms, 
Ankle-brachial index, for lower extremity arterial 
endovascular treatment, 579-597 
disease, 491, 492
Subject Index | Cardiol Clin 20 (2002) 645-662 
surgical treatment, 563-578  in structurally normal heart, 351-353 
carotid stenosis, medical and surgical aspects,  in tetralogy of Fallot, 353-355 
599-609  in transposition of the great arteries after 
percutaneous treatment, 589-597  Mustard or Senning procedure, 355 
central and peripheral, hypertensive, 238, 239  role of in congenital heart disease, 351-366 
diagnostic implications of, 238  in structurally normal heart, booster pump 
epidemiology of, 238  function of, 352, 353 
pathophysiology and treatment of, 238  conduit function of, 352 
prevention of, 239  hemodynamic function of, 351-353 
prognosis of, 238, 239  reservoir function of, 351. 352 
intermittent claudication, 521-534 
Atrial fibrillation, in congenital heart disease, 458 
limb ischemia, acute, 513-520 
hypertensive, 237, 238 
chronic critical, 535-545 
lower extremity, diagnostic aspects, 491-500  Atrial flutter, and atrial arrhythmias, 358 
magnetic resonance angiographic techniques  in congenital heart disease, 458 
for diagnosis of, 501-512 
Atrioventricular synchrony, atrial arrhythmias 
mesenteric occlusive and aneurysmal, 611-621 
and, 357, 358 
molecular approaches to atherosclerosis 
treatment, 633-643  Autonomic dysfunction, evaluation of patients 
renal artery disease, atherosclerotic, 547-562  with, 291-293 
upper extremity, 623-631  biochemical assessment  in, 293 
noninvasive tests for, 292 
Arteries, great, transposition of. See 
response to meals in, 292, 293 
Transposition of the great arteries. 
hypertension in, 294-296 
Arteriography, for diagnosis of renal  blood volume and, 296 
vascular disease, 551-552  contribution  of baroreflex failure to, 294, 
at time of cardiac catheterization,  551—552  295 
inappropriate natriuresis as consequence of, 
Artifacts, in magnetic resonance angiography, 
295 
511-512 
incidence and severity of, 294 
Aspiration thrombectomy, percutaneous, for  long-term consequences of, 295, 296 
acute limb ischemia, 518  multiple system atrophy and residual 
sympathetic tone driving, 296, 297 
Aspirin, in early immediate treatment of acute 
pathophysiology of, 296-298 
coronary syndromes,  165, 166 
treatment of, 298-300 
Asymptomatic Carotid Atherosclerosis Study, 602  vasodilators for, 299, 300 
orthostatic hypotension in, and associated 
Atherosclerosis.  See also Arterial disease., 
hypertension, 291-302 
molecular approaches for treatment of, 
with blunted tachycardia, 291, 292 
633-643 
differential diagnosis of, 291 
bio-artificial graft conduits, 639 
pure autonomic failure (PAF) syndromes in, 
bypass vein graft atherosclerosis, 635-637 
gene-based interventions, potential for,  293, 294 
pathophysiology of hypertension in, 297, 
633-635 
298 
hyperlipidemia, 640-641 
postangioplasty restenosis, 637-639  AV-synchrony. See Atriouentricular synchrony. 
therapeutic angiogenesis, 639-640 
Atherosclerotic renal artery disease, 547-562 
B 
Atria, hemodynamic function of, and Fontan 
Balloon angioplasty, for carotid stenosis, 589 
procedure, 356 
and stent implantation for upper extremity 
and postoperative pattern of atrial filling, 
arterial disease, 629-630 
353 
in specific conditions, 353-356  Beck, Claude,  13
648  Subject Index | Cardiol Clin 20 (2002) 645-662 
Beta blockers as antihypertensive drugs, adverse  in special populations and circumstances, 219, 
effects of, 268  220 
clinical pharmacology of, 267, 268  ultrasound techniques of, 208 
use of stethoscope bell in, 213 
Bio-artificial grafts, molecular approach to 
white coat effect in, 212, 213 
designing, 639 
wrist monitors for, 215 
Biofeedback, and hypertension, 259 
Brain, as target organ in hypertension, 225—247 
b-Blockers, in acute coronary syndromes,  150 
Bretylium, in cardiac arrest, 80-82 
in acute ischernic syndromes,  170 
Bright’s disease, hypertension and, 282 
Blood pressure, elevation of. See Hypertension. 
Bypass procedures, in patients with critical limb 
Blood pressure control, normal,  195-198 
ischemia, 540-541 
antidiuretic hormone activity in, 197, 198 
feedback mechanisms in,  Bypass vein graft atherosclerosis, prevention of, 
195-197  molecular approach to, 635-637 
intermediate-acting mechanisms of, 197, 
198 
C 
late-acting mechanisms of, 198 
physiology of, 195-198 
rapid-acting mechanisms of, 195, 197  C-reactive protein, role of, in peripheral arterial 
renin-angiotensin systems in, 197, 198  disease, 525-526 
Blood pressure measurement, ambulatory, 217  Calcium, and hypertension, 255 
monitors for, 216  Calcium channel antagonists, in acute ischemic 
aneroid devices for, 212 
syndromes,  171 
auscultatory gap in, 214 
auscultatory method of, 208  Calcium channel blockers as antihypertensive 
technical sources of error with, 214, 215  drugs, adverse effects of, 275 
clinical pharmacology of, 274, 275 
in the clinic, 217 
clinical importance of, 218  Captopril renography, in diagnosis of renal artery 
combined use of clinic, home, and ambulatory  stenosis, 555 
monitoring of, 218 
Cardiac arrest, pressor drugs in treatment of, 
cuff-inflation hypertension and, 210 
61-78 
devices for, 210-217 
validation of, 210, 211  Cardiac catheterization,  in assessment of right 
in different situations, 217  ventricular function, 345 
during exercise, 220  renal arteriography at time of, 551-552 
effects of body position on, 209, 210 
Cardiac chamber enlargement and wall 
effects of cuff size on, 210 
hypertrophy, hypertensive, diagnostic 
effects of posture on, 209 
evaluation of, 230 
in the elderly, 219 
epidemiology of, 228, 229 
electronic monitors for self-monitoring of, 
pathophysiology of, 229, 230 
215-217 
prevention of, 231, 232 
finger cuff method of, 208, 209, 215, 216 
prognosis of, 230, 231 
Hawksley Random Zero device for, 212 
treatment of, 230 
in infants and children, 219, 303 
locations for, 207, 208  Cardiopulmonary resuscitation (CPR), active 
mercury sphygmomanometers for, 211  compression-decompression, 40-44 
oscillometric technique of, 208  practical aspects of, 51-54 
by the patient, 217  rescuer fatigue in, 51 
potential sources of error in, 209, 210  basic life support,  1-12 
in pregnant women,  219  blood flow during, abdominal pump 
principles and techniques in, 207-223  mechanism of, 38 
rate of cuff inflation and deflation in, 213  cardiac pump mechanism of, 38, 42
Subject Index | Cardiol Clin 20 (2002) 645-662 
mathematical model of, 39  Carotid endarterectomy, for carotid stenosis, 
modern physiology of, 38-44  601-607 
thoracic pump mechanism of, 38, 42, 43  acute internal carotid artery occlusion, 
breathing techniques in, bag mask device in,  605-606 
6-8  after a fixed stroke, 605 
cricoid pressure and, 8  after stroke in evolution/crescendo TIA, 
mouth-to-barrier device, 4-6  605 
mouth -to-mask, 5—7  in asymptomatic disease, 601-603 
mouth-to-mouth, 3, 4  concomitant carotid and coronary disease, 
mouth-to-nose, 4  606 
use of face shield in, 5  predictors of perioperative risk, 601 
by one rescuer,  10, 11  restenosis after, 606 
by two rescuers,  11  in symptomatic disease, 603-605 
circulatory adjuncts of, 37-59  technical controversies in, 606-607 
warnings about general use of, 56  anesthesia, general vs.  regional, 
four-phase, 49-53  606-607 
interposed abdominal compression,  intraoperative shunting, 607 
45-49  primary repair vs.  patch closure, 607 
combining of with active compression- 
Carotid restenosis, after endarterectomy, 606 
decompression cardiopulmonary 
resuscitation, 55, 56  Carotid stenosis, diagnosis, 600-601 
coordination of chest and abdominal  medical and surgical aspects, 599-609 
compressions in, 54, 55  anticoagulation, 600 
hand position and compression technique  antiplatelet therapy, 599-600 
in, 54  carotid endarterectomy, 601-607 
practical aspects of, 54-56  lipid-lowering therapy, 600 
training individuals to do, 55  percutaneous treatment  for, 589-587 
newer methods of, circulatory adjuncts as,  balloon angioplasty, 589 
37-59  stenting, 589-592 
performance of, 2-11  adjuvant pharmacological therapy, 
quality of, during rescue efforts,  1, 2  593 
steps in, airway opening as, 2, 3  emboli protection during, 592-593 
assessment of responsiveness and activation  surgery us., 593-594 
of response system as, 2 
Catheterization, cardiac, renal arteriography at 
breathing as, 3-8 
time of, 551-552 
checking for signs of circulation as, 8, 9 
chest compressions as, 9, 10  Celiac artery aneurysms,  618 
use of pressor drugs in, 74, 75  Chain of Survival, of American  Heart 
Cardio Pump, 51  Association,  | 
Cardiovascular disease, mortality from, 187  Chest pain, acute ischemic, algorithm for, 160, 
161 
Cardiovascular Health Branch of Centers for 
clinical classification of, 142 
Disease Control, 324, 325 
low-risk patients with, clinical recognition of, 
Cardioverter-defibrillator,  internal, defibrillation  118 
in patients with, 16  management of, 118 
traditional management of, limitations of, 
Carnitine, L-, for intermittent claudication, 527 
117, 118 
Carotid artery disease, extra-cranial, magnetic 
Chest pain centers, accelerated diagnostic 
resonance angiography of, 508-511 
protocols in, 122 
Carotid Artery Stenosis with Asymptomatic  for acute ischemic syndromes, 
Narrowing, Operation Versus Aspirin study,  117-136 
602-603  cardiac serum  markers in, 125, 126
650  Subject Index | Cardiol Clin 20 (2002) 645-662 
Chest pain centers (continued )  Congenital heart disease, and genetic 
clinical guidelines, critical pathways,  heterogeneity, 387 
algorithms, and protocols in, 123, 124  atrial arrhythmias in. assessment of, 458, 459 
utility of, 124, 125  atrial defibrillators for, 461, 462 
coronary angiography in, 132  catheter ablation for, 461 
cost-effectiveness of, 123  drug therapy for, 460, 461 
development of, 119  pacing therapy for, 461 
early noninvasive cardiac testing in, 126-132  prevention of, 463, 464 
echocardiography in, 128-130  surgery for, 462, 463 
electron beam computed tomography in, 131,  therapy for, 459-463 
132  types of, 457, 458 
exercise testing in, 126-128  atrial fibrillation in, 458 
initial patient triage in, 120-122  atrial ventricular nodal reentrant tachycardia 
management of low-risk patients with negative  in, 458 
findings in, 132  atrioventricular reentrant tachycardia 
myocardial scintigraphy in, 130, 131  secondary to a bypass tract or Wolff- 
new electrocardiographic methods in, 125  Parkinson-White syndrome, 457, 458 
predictive instruments in, 123  catheter and surgical ablation in, 467-484 
rationale for, 118, 119  classic atrial flutter in, 458 
staffing of, 119, 120  counseling patients on risk of recurrence of, 
389 
Cholinergic fibers, in autonomic nervous system, 
definition of, 383 
62 
difficulties in recognizing genetic causes of, 
Chronic critical limb ischemia.  See Critical limb  385-387 
ischemia.  focal atrial tachycardia in, 458 
genetics of, 383-392 
Cigarette smoking, and hypertension, 259 
genomics and, 389, 390 
Cilostazol, for intermittent claudication, 526  identifying possible genetic causes of, 384, 385 
incisional atrial reentrant tachycardia in, 458 
Circulatory adjuncts, in cardiopulmonary 
molecular genetic studies and, 39i 
resuscitation, 37-59 
warnings about general use of, 56  origins of in fetal life, 367-382 
advances in genetics and, 367, 368 
Claudication, intermittent.  See Intermittent  possibility of prevention of, 390 
claudication.  pulmonary arterial hypertension in, 439-455 
Clinics, nurse-managed, in prevention and  reduced penetrance in, 387 
role of animal models of, 390, 391 
treatment of hypertension, 329, 330 
role of atria in, 351-366 
Clonidine as antihypertensive drug, clinical 
and significance of identifying disease-causing 
pharmacology of, 269, 270 
genes, 388 
Colic artery aneurysms, 619  single gene inheritance and, 388, 389 
tachyarrhythmias in, 468 
Combined alpha and beta blockers as 
novel technology for treatment of, 476, 477 
antihypertensive drugs, adverse effects of, 269 
surgical treatment of, 469-471 
clinical pharmacology of, 269 
three-dimensional electrical reconstruction 
Combitube, Esophageal-Tracheal, 24, 26, 27  in, 477, 478 
three-dimensional electroanatomical 
Community health systems partnerships, for 
reconstruction in, 476, 477 
hypertension prevention, with barbershops, 
three-dimensionai navigational 
beauty salons, and fire stations, 328 
reconstruction in, 477, 479 
with faith-based organizations, 327, 328 
transcatheter radiofrequency current 
with pharmacists, 328 
ablation for, 471-473 
with work sites, 326, 327 
variable expressivity and  NK X2.5 mutations 
Compliance, patient, and control of hypertension,  in, 387, 388 
188
Subject Index | Cardiol Clin 20 (2002) 645-662 
Congestive heart failure, due to renal artery  Critical limb ischemia, chronic, 535-545 
stenosis, 551  economic costs of, 535 
revascularization for control of, 560  failed grafts as cause of, 541-542 
graft surveillance,  542 
Coronary artery disease, concomitant carotid 
management of, 542 
artery disease and, 606 
failing graft, management of, 542- 
hypertensive, 236, 237 
incidence and prevalence, 535 
diagnostic implications of, 236 
laboratory testing, vascular, 537 
epidemiology of, 236 
long-term fate of patient with, 535 
pathophysiology of, 236 
medical management,  537-538 
prevention of, 237 
presenting features and physical examination, 
treatment and prognosis of, 236, 237 
536-537 
mortality from,  187, 188 
primary amputation, 543 
Coronary syndromes, acute,  159  revascularization approaches, 538-539 
adjunctive therapy for, 150-152  risk factors for, 535-536 
algorithm for, 162  surgical management,  539-540 
angiotensin-converting enzyme inhibition in,  of outflow disease, 540—541 
151 
Cushing’s syndrome, as cause of secondary 
B-blockers in, 150 
hypertension, 284, 285 
cardiogenic shock as, treatment for, 144-146 
diagnostic tests for, 285 
clinical symptoms of, 141, 142 
therapy for, 285 
coronary or myocardial reflow in, 139, 140 
coronary patency in, strategies for establishing 
or maintaining,  137-157  D 
magnesium in, 152  Defibrillation,  13-21 
nitrates in, 151, 152  early, principle of, 16, 17 
open artery and survival in, 139  effect of water on,  16 
pathophysiology of, 137-139  electrode size and position in, 15 
percutaneous coronary intervention for, versus  external, automated,  15, 16 
fibrinolysis,  146, 148  on airlines,  17, 18 
in perspective,  153, 154  in casinos,  18 
prehospital fibrinolysis for, 144  in police cars,  17 
primary stenting and facilitated  history of, 13, 14 
percutaneous coronary intervention and  in the hospital,  19 
fibrinolysis in, 149, 150  in patients with pacemaker/internal 
reperfusion era in, 137-157  cardioverter defibrillator,  16 
risk stratification  of, 143, 144  pediatric,  19 
biochemical cardiac markers in, 143  presence of nitroglycerin paste or other 
and the elderly, 148, 149  transdermal medication in, 16 
initial, 140-143  public access,  17-19 
ST-segment in, 142, 143  trial of, 18, 19 
ST-segment elevation myocardial infarction as,  special circumstances during,  16 
heparin in, 150  transthoracic impedance in, 14, 15 
treatment of, 144  waveform technology in, 14 
treatment of, aspirin in, 165, 166 
Diabetes mellitus, hypertension in, 313-315 
early immediate,  164-166 
active drug treatment trials for, 314, 
glycoprotein IIb/IIIa inhibitors in, 166 
315 
morphine in, 165 
and drug studies that included normoten- 
nitroglycerin in, 164, 165 
sive people, 315 
oxygen in, 164 
subsequent,  166-171  Diabetes mellitus (Continued ) 
treatment strategies for, 144-153  epidemiology of, 313, 314 
unstable angina non-ST-segment elevation  therapeutic recommendations for, 315 
myocardial infarction as, 152, 153  risk factor for critical limb ischemia, 537
652  Subject Index | Cardiol Clin 20 (2002) 645-662 
Dietary Approaches to Stop Hypertension  Endovascular treatment, of abdominal aortic 
(DASH) trial, 251-253  aneurysms, 579-597 
early experience, 579-581 
Digital subtraction angiography, x-ray, for lower 
future perspectives, 586-587 
extremity arterial disease diagnostics, 498-499 
indications for, 586 
Diuretics as antihypertensive drugs, clinical  problems with current endograft devices, 
pharmacology of, 265, 266  583-586 
adverse effects of, 265  endoleak, 583-585 
special categories of, clinical pharmacology of,  morphological and structural changes, 
265  585 
secondary interventions after, 585-586 
Doppler analysis, for lower extremity arterial 
with Vanguard device, 581-583 
disease diagnosis, 493 
for acute limb ischemia, 516 
of upper extremity arterial disease, 627 
for critical limb ischemia, 538-539 
Down syndrome, in tetralogy of Fallot, 387  for intermittent claudication,  529-531 
Duplex sonography, arterial, for diagnosis of  Epinephrine, 62, 64, 65 
arterial disease, lower extremity, 494-495  alternatives to, 70-74 
upper extremity, 627  in cardiac arrest, dosage of, 67—70 
for renal artery stenosis diagnosis, 552-553  current recommendations for, 74 
Dysbetalipoproteinemia, familial, type III, role of,  and neurologic outcome, 66 
in peripheral arterial disease, 525  pharmacology of, 65, 66 
toxicity of, 66, 67 
and ventricular fibrillation, 66 
E 
European Carotid Surgery Trial, 603-604 
Ebstein’s anomaly, of tricuspid valve, 429-437 
Exercise, as therapy for intermittent claudication, 
clinical presentation and diagnostic 
526 
evaluation of, 431-434 
pathophysiology of, 430, 431  Extremities, arterial disease of, lower, diagnostic 
pregnancy and, 434  aspects of, 491-500 
prognosis of, 435, 436  upper, 623-631 
tachycardia associated with, 468, 469 
therapy for, 434, 435 
F 
Echo-Doppler measurements, in assessment of 
Failure, of graft. See Graft failure. 
right ventricular function, 346, 347 
Fetal heart development,  368-381 
Embolism, causing acute limb ischemia, 514 
aortic and pulmonary trunk development in, 
paradoxical, and patent foramen ovale, 362  376-378 
protection against, during percutaneous 
abnormal,  376, 377 
carotid intervention,  592-593 
genetics of, 377, 378 
of superior mesenteric artery, acute intestinal 
normal, 376 
occlusion due to, 614-616 
atrioventricular valve development in, 375, 376 
Emergency care, cardiopulmonary resuscitation  abnormal, 375 
in, 2-11  genetics of, 375, 376 
normal, 375 
Emergency medical services (EMS) systems, in 
development of the aorta and its branches in, 
acute ischemic syndromes,  105-107 
378-381 
access to, 105, 106 
abnormal, 379-381 
dispatch of, 106 
genetics of, 381 
hospital triage and EMS planning in, 107 
normal, 378, 379 
levels and types of service by, 106, 107 
from fertilization to primitive heart tube, 
Endarterectomy, carotid. See Carotid  abnormal, 368 
endarterectomy.  genetics of, 368, 369 
for upper extremity arterial disease, 629-630  normal, 368
Subject Index | Cardiol Clin 20 (2002) 645-662  653 
from looping to wedging, 370-372  Graft failure, as cause of critical limb ischemia, 
abnormal, 371  541-543 
genetics of, 371, 372  early failure, 541 
normal, 370, 371  graft surveillance,  542 
from primitive heart tube through looping,  late failure, 541-542 
369, 370  management of patient with failed graft, 
abnormal,  369, 370  542 
genetics of, 370  management of patient with failing graft, 
normal, 369  542-543 
septation of the atria in, 372-375 
Graft infection, after surgery for abdominal aortic 
abnormal, 373, 374 
aneurysms,  574 
genetics of, 374, 375 
normal, 372, 373  Graft surveillance, in critical limb ischemia, 542 
for lower extremity arterial disease diagnosis, 
Fetus, origins of congenital heart disease in, 
495-496 
367-382 
Grafts, bypass, atherosclerosis of, prevention of, 
Fibrillation, atrial. See Atrial fibrillation 
molecular approach to, 635-637 
Finger pressures, for diagnosis of upper extremity  prosthetic, molecular approach to designing 
arterial disease, 626  bioartificial graft conduits, 639 
Fish oil, and hypertension, 255  Guanethidine as antihypertensive drug, clinical 
pharmacology of, 270, 271 
Fontan procedure, postoperative hemodynamic 
function in, 356 
H 
Foot care, in critical limb ischemia, 537 
Heart, fetal development of. See Fetal heart 
Foramen ovale, patent. See Patent foramen  development. 
ovale.  as target organ in hypertension, 225-247 
asymptomatic left ventricular systolic 
G  dysfunction from, 234, 235 
cardiac arrhythmias and su:iden death 
Gadolinium-based magnetic resonance 
from, 237, 238 
angiography, 503-505 
cardiac chamber enlargement and wall 
dosage, 503-504 
hypertrophy from, 228-232 
paramagnetic contrast agents for, 503 
chronic heart failure from, 235, 236 
parameters for optimal, 504-505 
coronary heart disease from, 236, 237 
spoiled gradient echo imaging, 504 
left ventricular diastolic dysfunction from, 
Gastric artery aneurysms, 618-619  23525250 
Gastroduodenal artery aneurysms,  619-620  Heart failure, chronic, hypertensive, diagnostic 
Gastroepiploic artery aneurysms,  implications of, 235 
618-619  epidemiology of, 235 
treatment and prognosis of, 235 
Gastrointestinal complications, after surgery for  treatment  of, 235, 236 
abdominal aortic aneurysms, 574 
Heath-Edwards classification of pulmonary 
Gene-based interventions, potential, for treatment  vascular changes in congenital heart disease, 
of atherosclerosis, 633-635  441, 442 
Genetics, advances in, and understanding of the  Hemorrhage, after surgery for abdominal aortic 
origins of congenital heart disease, 367, 368  aneurysms, 573 
Glomerulonephritis, hypertension and, 282  Heparin, in ST-segment elevation myocardial 
Glycemic control, to reduce intermittent  infarction,  150, 151 
claudication,  524  Hepatic artery aneurysms, 617-618
654  Subject Index | Cardiol Clin 20 (2002) 645-662 
Homocysteine, role of, in peripheral arterial  lifetime risk of, 192 
disease, 525  obesity and, 258, 259 
in orthostatic hypotension and autonomic 
Hydralazine as antihypertensive drug, clinical 
dysfunction, 291-302 
pharmacology of, 275, 276 
pathogenesis, and clinical physiology of, 
Hyperlipidemia, correction of, to reduce  195-206 
intermittent claudication, 523  in renal artery stenosis, 547-548, 550 
experimental genetic treatment of, 640-641  pathophysiologic states of, 198-203 
pheochromocytoma as cause of, 285 
Hypertension, in African-Americans,  307-309 
diagnostic tests for, 285 
alcohol consumption and, 255, 256 
therapy for, 285 
background information on, 321 
physical activity and, 256, 257 
bad news about,  182, 184 
posttransplantation,  311-313 
calcium and, 255 
potassium and, 255 
in children, 303-305 
blood pressure measurement in, 303  in pregnancy,  305-307 
prevalence in the general population,  187 
diagnostic evaluation of, 304, 305 
prevalence of, in United States,  181 
etiology of, 303, 304 
prevention and control of. See also Blood 
treatment of, 305 
pressure control. 
cigarette smoking and, 259 
community health systems partnerships for, 
clinical care and, 329, 330 
326-328 
in nurse-managed clinics, 329, 330 
community outreach for, 328, 329 
community outreach for, 328, 329 
nondrug interventions in, 249-263 
control of. See also Blood pressure control. 
public health approaches to, 321—324 
in Latin American countries,  189 
salt intake and, 249-254 
patient compliance and, 188 
primary, pathogenesis of, 199-203 
to reduce intermittent claudication, 
renin-angiotensin system and, 201, 202 
523-524 
role of genes in, 199, 200 
control rates of, worldwide,  182 
role of the environment in, 200 
cuff-inflation, 210 
Cushing's syndrome as cause of, 284, 285  role of the kidney in, 202, 203 
sympathetic nervous system and, 200, 
diagnostic tests for, 285 
therapy for, 285  201 
vascular remodeling, hypertrophy, and 
detection and control of, population and 
increased peripheral resistance and, 202 
policy implications of, 187-194 
primary aldosteronism as cause of, 284 
in diabetes mellitus, 313—315 
diagnostic tests for, 284 
and dietary factors other than sodium intake, 
254, 255  therapy for, 284 
pulmonary arterial. See Pulmonary arterial 
education about, community health system 
hypertension. 
partnerships for, 326-328 
relative risk of, 192 
effective strategies for, 321-332 
renal artery stenosis as cause of, 282, 283 
fish oil and, 255 
diagnostic tests for, 283 
global burden of, 181-185 
therapy for, 283 
recommendations for reducing, 184 
renoparenchymal disease as cause of, 283, 284 
global risk assessment  in, 191 
diagnostic tests for, 284 
good news about,  181, 182 
therapy for, 284 
heart, kidney and brain as target organs in, 
resistant, 281, 282 
225-247 
causes of, 281 
clinical presentations of damage to, 
definition of, 281 
228-241 
treatment of, 281, 282 
mechanisms of damage of, 227, 228 
risk stratification in, and global risk 
risk stratification and, 225, 226 
assessment, growing importance of, 
spectrum of damage to, 225-228 
189-193 
in kidney disease, 309-311