Table Of ContentCARDIOLOGY 
CLINICAL 
QUESTIONS
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CARDIOLOGY 
CLINICAL 
QUESTIONS
John P. Higgins, MD, MBA, MPHIL, FACC, FACP, FAHA, FASNC, FSGC
ACSM Certifi ed Clinical Exercise Specialist & Certifi ed Personal Trainer
Associate Professor of Medicine
The University of Texas Health Science Center at Houston (UTHealth)
Director of Exercise Physiology
Memorial Hermann Sports Medicine Institute
Chief of Cardiology, Lyndon B. Johnson General Hospital 
Principal Investigator HEARTS 
(Houston Early Age Risk Testing & Screening Study)
Houston, Texas
Asif Ali, MD
Clinical Assistant Professor
Division of Cardiovascular Medicine
The University of Texas Health Science Center at Houston (UTHealth)
Memorial Hermann Heart and Vascular Institute 
Sub-Clinical Investigator HEARTS
(Houston Early Age Risk Testing & Screening Study)
Houston, Texas
David M. Filsoof, MD
Division of Cardiovasuclar Medicine
Sub-Clinical Investigator of HEARTS 
(Houston Early Age Risk Testing & Screening Study) 
University of Texas-Houston Health Science Center
Houston, Texas
Mayo School of Graduate Medical Education
Jacksonville, Florida
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CONTENTS
Faculty Advisors  .................................................... xiii
Preface  ................................................................. xv
Acknowledgments  ................................................... xix
Section I. Diagnostic Testing
Does my patient need an 
electrophysiological study?  .................................... 2
When do I need to order a stress test?  ................... 4
What are the indications/criteria for 
myocardial perfusion imaging?  .............................. 6
Should I refer my patient for 
coronary angiography?  .......................................... 8
When should I order an echocardiogram on 
my patient, and which type should I order?  .......... 10
Does my patient need cardiac pacing?  ................. 12
Does my patient need an implantable-
cardioverter-defi brillator (ICD)?  ......................... 14
Does my patient need further evaluation 
with cardiac computed tomography?  ................... 16
Section II. ACS
How do I use a TIMI risk score in the patient 
with unstable angina/non-ST elevation 
myocardial infarction (UA/NSTEMI)?  ................ 20
What is my initial management of an unstable 
angina (UA)/non-ST-elevation myocardial 
infarction (NSTEMI) patient?  ............................ 22
What is my initial management for an acute 
ST elevation myocardial infarction (STEMI)? ...... 24
v
vi CONTENTS
What initial reperfusion strategy should 
I begin in my patient with an acute STEMI? ........ 26
How do you manage a patient post-MI 
and treat the complications of MI?  ...................... 28
How do I manage variant angina?  ....................... 30
Should I refer my patient for PCI or CABG?  ....... 32
How do I determine the site of 
STEMI infarct/injury on ECG?  .......................... 34
How do I manage a patient with 
right/inferior myocardial infarction?  .................... 36
How to manage a patient with 
elevated troponins?  ............................................. 38
How do I manage a patient with chronic 
stable angina?  ..................................................... 40
Should our patient get an intra-aortic 
balloon pump placed?  ......................................... 42
How do I manage a patient presenting 
with cocaine-induced chest pain?  ........................ 44
Section III. Valvular Disease
Does my patient with aortic stenosis 
need surgery?  ..................................................... 48
Does my patient with aortic 
regurgitation need surgery?  ................................. 50
Does my patient with mitral stenosis 
need surgery?  ..................................................... 52
Does my patient with mitral regurgitation 
need surgery?  ..................................................... 54
How do I manage my pregnant patient 
with mitral stenosis?  ........................................... 56
Does my patient with tricuspid regurgitation 
need surgery?  ..................................................... 58
Does my patient have endocarditis?  ..................... 60
CONTENTS vii
Does my patient need endocarditis 
prophylaxis?  ....................................................... 62
Should I refer my patient with native 
valve endocarditis for surgery?  ............................ 64
How do I medically treat prosthetic 
valve endocarditis?  .............................................. 66
Should I refer my patient with prosthetic 
valve endocarditis for surgery?  ............................ 68
How do I medically treat endocarditis?  ................ 70
How to manage an infected pacemaker?  .............. 72
Section IV. Cardiac Diseases
Does my patient have amyloid 
cardiomyopathy?  ................................................ 76
How do I manage my patient with 
atypical angina (cardiac syndrome X)?  ................ 78
How do I manage acute pericarditis?  ................... 80
How do I manage cardiac tamponade?  ................ 82
What should I do if I suspect aortic 
dissection?  ......................................................... 84
How do I manage a patient with aortic 
dissection?  ......................................................... 86
How do I manage my patient with a left 
ventricular thrombus?  ......................................... 88
Does my pregnant patient have peripartum 
cardiomyopathy?  ................................................ 90
How do I diagnose a patient with deep 
venous thrombosis?  ............................................ 92
How do I manage a patient with deep 
venous thrombosis?  ............................................ 94
How do I diagnose pulmonary embolism 
in my patient?  .................................................... 96
viii CONTENTS
How do I treat my patient with acute 
pulmonary embolism?  ........................................ 98
Does my patient have pheochromocytoma?  ....... 100
How do I manage a patient with 
pheochromcytoma?  .......................................... 102
How do you manage a patient with 
myocarditis?  ..................................................... 104
Section V. Examination
What are the abnormal pulses in my 
patient and what cardiac conditions 
are they associated with?  ................................... 108
What is the likely heart murmur I hear?  ............. 110
Does my patient need preoperative 
cardiac testing for noncardiac surgery?  .............. 112
How do I interpret my patients 
Swanz–Ganz catheterization?  ............................ 114
Does my patient need screening for an 
abdominal aortic aneurysm (AAA)?  .................. 116
Section VI. Arrhythmias
How do I manage the rate and rhythm in 
my patient with atrial fi brillation?  ...................... 120
Should I start coumadin in my patient 
with atrial fi brillation?  ....................................... 122
How do I manage a patient presenting in 
acute atrial fl utter?  ............................................ 124
How do I manage my patient with 
Brugada syndrome?  .......................................... 126
How do I manage 3rd degree 
atrioventricular block?  ...................................... 128
How do I manage my patient with 2nd degree 
type I (Wenckebach) atrioventricular block? ....... 130
CONTENTS ix
How do I manage my patient with 2nd degree 
type II atrioventricular block?  ........................... 132
Is it ok for my patient to consume 
an energy beverage?  .......................................... 134
Does this ECG show changes of 
hyperkalemia?  .................................................. 136
Does this ECG show changes 
of hypokalemia? ................................................ 138
Does this ECG show changes 
of hypercalcemia?  ............................................. 140
Does this ECG show changes 
of hypocalcemia?  .............................................. 142
Does this ECG show right bundle 
branch block?  ................................................... 144
Does this ECG show left bundle 
branch block?  ................................................... 146
Does this ECG show left ventricular 
hypertrophy?  .................................................... 148
Does this ECG show second degree 
type I atrioventricular block?  ............................. 150
Does this ECG show second degree type II 
atrioventricular block (Mobitz II)?  .................... 152
Does this ECG show third degree 
atrioventricular block?  ...................................... 154
What should I do if my patient has 
premature ventricular contractions?  .................. 156
How do I manage a patient who presents 
with WPW?  ...................................................... 158
How do I acutely manage a patient with 
torsade de pointes (TdP)?  ................................. 160
Does this ECG show Wolff–Parkinson–White 
syndrome?  ....................................................... 162
Description:Cardiac Clinical Questions answers more than one-hundred of the clinical cardiology questions most frequently asked of the authors during consultation. The book simulates the consultation process: consult question →data collection→ synthesis of data → solution. After clarifying the key concept