Table Of ContentBRITISH  JOURNAL 
HAEMATOLOGY 
EDITORS:  [AN  HANN,  FINBARR  COTTER,  JOHN  REILLY 
ASSOCIATE  EDITORS 
H. E. Broxmeyer,  A. K. Burnett,  M. Greaves,  M. Y. Gordon, 
I. R. Peake,  M. J. Pippard,  I. A. G. Roberts,  N. Russell,  S. L. Thein,  L. Williamson 
EDITORIAL  BOARD 
I. R. Peake  Chairman 
R. Auer,  T. Baglin,  B. J. Bain,  M. Barnett,  B. Bennett,  J. Boultwood,  C. Camaschella, 
R. Chopra,  C. J. Eaves,  C. Fegan,  P. Fenaux,  A. Goodeve,  A. R. Green,  J. D. Griffin, 
H. Heslop,  T. L. Holyoake,  M. Le Beau,  D. Linch,  M. Makris,  C. Mecucci,  D. R. Miller, 
P. A. H. Moss,  A. Nurden,  D. Provan,  D. Pamphilon,  D. Rees,  D. Rund,  O. P. Smith, 
M. Worwood 
Volume  123 
Pages  1-968 
Dy 
Blackwell 
Publishing 
2003
©  2003  British Journal of Haematology Blackwell  Publishing Ltd 
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Volume  Contents 
BRITISH  JOURNAL  OF  HAEMATOLOGY 
Volume  123,  Issue  1, October-I  2003 
IMAGES  IN  HAEMATOLOGY 
Pulmonary veno-occlusive disease following allogeneic peripheral blood stem cell 
transplantation for chronic myeloid leukaemia 
M. Mukai,  M. Kondo,  T. Bohgaki, A. Notoya and M. Kohno 
Circulating neuroblastoma cells in peripheral blood 
V. Moodley and R. Pool 
HISTORICAL  REVIEWS 
William Osler’s legacy and his contribution to haematology 
M. J. Stone 
Paul Ehrlich’s doctoral thesis: a milestone in the study of mast cells 
E. Crivellato,  C. A. Beltrami,  F. Mallardi and D. Ribatti 
GUIDELINE 
Guidelines on the use of colony-stimulating factors in haematological malignancies 
A. Pagliuca,  P. A. Carrington,  R. Pettengell,  S. Rule and J. Keidan on behalf of the 
Haemato-Oncology  Task Force of the British Committefeo r Standards in Haematology 
HAEMATOLOGICAL  MALIGNANCY 
Ber-Abl upregulates cytosolic p21”“*'/C” “! by a phosphoinositide-3-kinase 
(PI3K)-independent  pathway 
K. Keeshan,  T. G. Cotter and S. L. McKenna 
Role of DNA mismatch repair genetic polymorphisms in the risk of childhood 
acute lymphoblastic leukaemia 
G. Mathonnet,  M. Krajinovic,  D. Labuda and D. Sinnett 
Prognostic significance of quantitative analysis of WT1  gene transcripts by 
competitive reverse transcription polymerase chain reaction in acute leukaemia 
M. Garg, H. Moore,  K. Tobal and J. A. L. Yin 
Geographical and ecological analyses of childhood acute leukaemias and 
lymphomas in north-west England 
R. J. Q. McNally,  R. D. Alston,  D. P. Cairns,  O. B. Eden and J. M. Birch 
The P2X7 receptor gene polymorphism  1513 A — C has no effect on clinical 
prognostic markers,  in vitro sensitivity to fludarabine,  Bcl-2 family protein 
expression or survival in B-cell chronic lymphocytic leukaemia 
J. Starczynski,  C. Pepper, G. Pratt,  L. Hooper, A. Thomas,  T. Hoy, D. Milligan, 
P. Bentley and C. Fegan
Volume  Contents 
Elevated levels of cyclin Al and A (A2) mRNA in acute myeloid leukaemia are 
associated with increased survival 
T. Nakamaki,  Y. Hamano,  J.-I. Hisatake, A. Yokoyama,  K.-I. Kawakami,  S. Tomoyasu, 
Y. Honma and P. Koeffler 
The impact of intensive antileukaemic treatment strategies on prognosis of 
myelodysplastic syndrome patients aged less than 61 years according to 
International  Prognostic Scoring System risk groups 
M. Oosterveld,  S. H. Wittebol,  W. A. J. G. Lemmens,  B. A. L. M. Kiemeney, A. Catik, 
P. Muus, A. V. M. B. Schattenberg and T. J. M. de Witte 
Prevalence and pattern of antinuclear autoantibodies in 347 patients with non- 
Hodgkin’s lymphoma 
S. Guyomard, G. Salles, M. Coudurier, H. Rousset, B. Coiffier, J. Bienvenu and N. Fabien 
Short  reports  100  Veno-occlusive disease in patients receiving thiopurines during maintenance 
therapy for childhood acute lymphoblastic leukaemia 
S. Stoneham,  L. Lennard,  P. Coen, J. Lilleyman and V. Saha 
Tandem high-dose therapy (HDT) for multiple myeloma: recombinant  human 
erythropoietin therapy given between first and second HDT allows second 
peripheral blood stem cell transplantation without red blood cell transfusion 
F. Baron,  P. Frere, G. Fillet and Y. Beguin 
Serum levels of macrophage inflammatory protein-1  alpha (MIP-1«) correlate 
with the extent of bone disease and survival in patients with multiple myeloma 
E. Terpos, M. Politou,  R. Szydlo, J. M. Goldman,  J. F. Apperley and A. Rahemtulla 
TRANSPLANTATION 
Long-term outcomes of allogeneic stem cell transplant recipients after calcineurin 
inhibitor-induced neurotoxicity 
R. Chohan,  R. Vij, D. Adkins,  W. Blum,  R. Brown,  M. Tomasson,  S. Devine, 
T. Graubert,  L. T. Goodnough, J. F. DiPersio and H. Khoury 
The use of stimulated granulocyte transfusions to prevent recurrence of past 
severe infections after allogeneic stem cell transplantation 
J. P. Kerr,  E. Liakopolou, J. Brown, J. M. Cornish,  D. Fleming, E. Massey, A. Oakhill, 
D. H. Pamphilon,  S. P. Robinson,  A. Totem,  A. M. P. I. Valencia and D. I. Marks 
Phenotype, function and chimaerism of monocyte-derived blood dendritic cells 
after allogeneic haematopoietic stem cell transplantation 
D. Nachbaur,  B. Kircher,  K. Eisendle,  K. Latzer,  M. Haun and G. Gastl 
PLATELETS,  HAEMOSTASIS  AND  THROMBOSIS 
Bernard-—Soulier syndrome due to the homozygous Asn-45Ser mutation in GPIX: 
an unexpected, frequent finding in Germany 
U. J. H. Sachs,  H. Kroll, A. C. Matzdorff,  H. Berghdfer, J. A. Lépez and S. Santoso 
Molecular, ultrastructural and functional characterization of a Spanish family 
with Hermansky—Pudlak syndrome: role of insC974 in platelet function and 
clinical relevance 
R. Gonzalez-Conejero,  J. Rivera,  G. Escolar,  I. Zuazu-Jausoro,  V. Vicente and J. Corral 
Short  reports  139  Beta-adrenergic receptor polymorphisms in patients with elevated factor VIII levels 
with venous thrombosis 
J. O'Donnell,  R. A. Manning and M. A. Laffan
Volume  Contents  Vv 
Intravenous anti-D as a treatment  for immune thrombocytopenic  purpura  (ITP) 
during pregnancy 
M. Michel,  M. V. Novoa and J. B. Bussel 
RED  CELLS  AND  IRON 
Pure red cell aplasia associated with expansion of CD3* CD8* granular 
lymphocytes expressing cytotoxicity  against  HLA-E” cells 
K. L. Mori,  H. Furukawa,  K. Hayashi,  K.-J]. J. Sugimoto and K. Oshimi 
A novel deletion causing (ey5p)° thalassaemia  in a Chilean family 
L. Game, J. Bergounioux,  J. P. Close,  B. E. Marzouka and S. L. Thein 
Quiescent CD34" early erythroid progenitors are resistant  to several erythro- 
poietic ‘inhibitory’ cytokines; role of FLIP 
J. Ratajczak,  M. Kucia,  R. Reca, J. Zhang,  B. Machalinski and M. Z. Ratajczak 
Short reports  Hypoxic response of iron absorption is not affected by the Hfe gene knock-out in mice 
A. H. Laftah,  R. J. Simpson, N. Beaumont,  8. Bahram,  K. Schtimann and S. K. S. Srai 
Cytogenetic abnormalities in paroxysmal nocturnal haemoglobinuria  usually 
occur in haematopoietic cells that are glycosylphosphatidylinositol-anchored 
protein (GPI-AP) positive 
E. M. Sloand,  M. Fuhrer,  K. Keyvanfar,  L. Mainwaring,  J. Maciejewski,  Y. Wang. 
S. Johnson,  A. J. Barrett and N. S. Young 
HAEMOPOIESIS  AND  LEUCOCYTES 
The type 1 CD10/neutral endopeptidase 24.11  promoter:  functional character- 
ization of the 5’-untranslated region 
N. Sezaki,  F. Ishimaru,  T. Tabayashi,  I. Kataoka,  K. Nakase,  K. Fujii,  T. Kozuka, 
H. Nakayama,  M. Harada and M. Tanimoto 
CORRESPONDENCE 
Paediatric myelodysplasia 
M. M. Reid 
Paediatric myelodysplasia — response to M. M. Reid 
S. J. Passmore,  C. A. Stiller,  H. Kempski and I. M. Hann 
ERRATA 
BOOK  REVIEWS 
ANNOUNCEMENT 
Volume  123,>   Issue  2, October-II  2003 
IMAGES  IN  HAEMATOLOGY 
Malignant sarcoma masquerading as a pseudotumour in a patient  with mild 
haemophilia 
P. Connor,  B. Cheung and S. Rangarajan 
192  Atypical large granular lymphocytes in a child 
F. Girodon,  L. Faivre,  N. Devillier,  P. M. Carli and M. Maynadie
Volume  Contents 
REVIEW 
The role of haploidentical stem cell transplantation in the management of children 
with haematological disorders 
P. Veys, P. Amrolia and K. Rao 
HISTORICAL  REVIEW 
Haematology at the Hammersmith hospital and Royal Postgraduate Medical 
School  1934-1994 
A. V. Hoffbrand 
HAEMATOLOGICAL  MALIGNANCY 
Cytogenetic findings in adult de novo acute myeloid leukaemia. A population-based 
study of 303/337 patients 
B. S. Preiss,  G. B. Kerndrup,  K. G. Schmidt,  A. G. Sorensen,  N.-A.  T. Clausen, 
O. V. Gadeberg,  T. Mourits-Andersen and N. T. Pedersen on behalf of the AML study 
Group Region of Southern Denmark 
Possible regulation of Wilms’ tumour gene 1 (WT1) expression by the paired box 
genes PAX2 and PAX8 and by the haematopoietic transcription factor GATA-1  in 
human acute myeloid leukaemias 
J. M. Siehl, E. Thiel, K. Heufelder, E. Snarski, S. Schwartz,  V. Maildnder and U. Keilholz 
Clinical significance of residual disease during treatment  in childhood acute 
myeloid leukaemia 
E. Coustan-Smith,  R. C. Ribeiro,  J. E. Rubnitz,  B. I. Razzouk,  C.-H.  Pui, 8. Pounds, 
M. Andreansky,  F. G. Behm, S. C. Raimondi,  S. A. Shurtleff, J. R. Downing and 
D. Campana 
Occurrence of dysregulated oncogenes in primary plasma cells representing 
consecutive stages of myeloma pathogenesis: indications for different disease 
entities 
T. Rasmussen,  K. Theilgaard-Monch,  H. R. Hudlebusch,  M. Lodahl,  H. E. Johnsen and 
I. M. S. Dahl 
Enhanced production of ostecpontin in multiple myeloma: clinical and pathogenic 
implications 
Y. Saeki, T. Mima, T. Ishii, A. Ogata, H. Kobayashi, S. Ohshima, T. Ishida, Y. Tabunoki, 
H. Kitayama, M. Mizuki, Y. Katada, H. Asaoku, M. Kitano, N. Nishimoto, K. Yoshizaki, 
M. Maeda, S. Kon, N. Kinoshita,  T. Uede and I. Kawase 
Chlorambucil in combination with induction and maintenance rituximab is 
feasible and active in indolent  non-Hodgkin's lymphoma 
G. Martinelli,  D. Laszlo,  F. Bertolini,  R. Pastano,  P. Mancuso,  A. Calleri, A. Vanazzi, 
P. Santoro,  F. Cavalli and E. Zucca 
Successful treatment of refractory pure red cell aplasia associated with lympho- 
proliferative disorders with the anti-CD52 monoclonal antibody alemtuzumab 
(Campath-1H) 
X. Ru and H. A. Liebman 
Predictive value of early '*F-fluoro-deoxyglucose positron emission tomography in 
chemosensitive relapsed lymphoma 
B. Schot, G. van Imhoff, J. Pruim,  W. Sluiter,  W. Vaalburg and E. Vellenga
Volume  Contents  Vii 
DNA microarray analysis of stage progression mechanism in myelodysplastic 
syndrome 
M. Ueda, J. Ota,  Y. Yamashita,  Y. L. Choi,  R. Ohki,  T. Wada,  K. Koinuma,  Y. Kano, 
K. Ozawa and H. Mano 
Granulomatous slack skin disease — disease features and response to pentostatin 
N. Osuji,  L. Fearfield,  E. Matutes,  A. C. Wotherspoon,  C. Bunker and D. Catovsky 
Short report  Plasma levels of tumour necrosis factor alpha and interleukin-6 predict 
progression-free survival following thalidomide therapy  in patients with 
previously untreated multiple myeloma 
M. A. Thompson, T. E. Witzig, S. Kumar, M. M. Timm, J. Haug, R. Fonseca, P. R. Greipp, 
J. A. Lust and S. V. Rajkumar 
TRANSPLANTATION 
T- and B-cell immune reconstitution and clinical outcome  in patients with 
multiple myeloma receiving T-cell-depleted, reduced-intensity allogeneic stem cell 
transplantation with an alemtuzumab-containing conditioning regimen followed 
by escalated donor lymphocyte infusions 
S. D’Sa,  K. Peggs, A. Pizzey, S. Verfuerth,  D. Thuraisundaram,  M. Watts,  H. White, 
G. Hale, H. Waldmann,  A. Goldstone,  S. Mackinnon and K. Yong 
Short report  T-cell alloreactivity dominates natural killer cell alloreactivity in minimally T-cell- 
depleted HLA-non-identical paediatric bone marrow  transplantation 
E. J. Lowe,  V. Turner,  R. Handgretinger,  E. M. Horwitz,  E. Benaim,  G. A. Hale, 
P. Woodard and W. Leung 
PLATELETS,  HAEMOSTASIS  AND  THROMBOSIS 
Pregnancy-associated venous thromboembolism (VTE) in combined heterozygous 
factor V Leiden (FVL) and prothrombin (FII) 20210 A mutation  and in 
heterozygous FII single gene mutation alone 
M.-M.  Samama,  R. A. Rached,  M.-H.  Horellou,  S. Aquilanti,  V. G. Mathieux, 
G. Plu-Bureau,  I. Elalamy and J. Conard 
A multicentre assessment of the endogenous thrombin potential using a 
continuous monitoring amidolytic technique 
A. S. Lawrie,  E. Gray, D. Leeming,  S. J. Davidson,  G. Purdy, R. lampietro,  S. Craig, 
P. Rigsby and I. J. Mackie 
Short report  Two novel factor V null mutations associated with activated protein C resistance 
phenotype/genotype discrepancy 
Y. Dargaud,  M. C. Trzeciak,  S. Meunier,  C. Angei, D. Pellechia,  C. Négrier and 
C. Vinciguerra 
RED  CELLS  AND  IRON 
Familial polycythemia vera with Budd—Chiari syndrome in childhood 
H. Cario, H. L. Pahl,  K. Schwarz,  C. Galm, M. Hoffmann,  M. Burdelski,  E. Kohne and 
K.-M.  Debatin 
Heterocellular hereditary persistence of fetal haemoglobin affects the haematological 
parameters of B-thalassaemia trait 
C. Garner,  T. K. Dew,  R. Sherwood,  D. Rees and S. L. Thein
viii  Volume  Contents 
Causes of death in sickle cell disease: an autopsy study 
E. A. Manci,  D. E. Culberson,  Y.-M.  Yang, T. M. Gardner,  R. Powell, J. Haynes Jr, 
A. K. Shah and V. N. Mankad and Investigators of the Cooperative Study of Sickle Cell 
Disease 
CORRESPONDENCE 
Concomitant myelodysplastic syndrome and chronic myeloid leukaemia: treatment 
outcomes with imatinib mesylate 
R. A. Mesa,  D. P. Steensma,  J. Hoyer and R. P. Ketterling 
Severe acute respiratory syndrome and lupus anticoagulants in children 
E. Y. Chow and W. K. Chiu 
Malignancies in sickle cell disease patients treated with hydroxyurea 
A. Ferster,  E. Sariban and N. Meuleman for the Belgian Registry of Sickle Cell Disease 
patients treated with Hydroxyurea 
Lithium effects on neutrophil motility in Shwachman—Diamond syndrome: 
evaluation by computer-assisted image analysis 
A. Azzara,  G. Carulli and M. Petrini 
Prognostic features of splenic lymphoma with villous lymphocytes 
E. Iannitto,  E. Ammatuna,  A. M. Florena and V. Franco 
Erythrocytosis and the Chuvash von Hippel-Lindau mutation 
M. J. Percy, M. E. J. Beard,  C. Carter and S. L. Thein 
Endothelial cells express normal cellular prion protein 
R. Starke, P. Harrison,  R. Gale, I. Mackie, O. Drummond,  I. MacGregor and S. Machin 
Heparin-induced thrombocytopenia:  pathogenesis and management 
R. A. Saad 
Heparin-induced thrombocytopenia: pathogenesis and management — Response to 
Rasheed Saad 
T. E. Warkentin 
Volume  123,  Issue  3, November-I  2003 
IMAGES  IN  HAEMATOLOGY 
Splenunculectomy  in autoimmune thrombocytopenic purpura 
P. A. Fields,  H. Cohen and K. G. Patterson 
Splenosis peritonei 
S. Luminari,  M. De Santis,  A. Casolo and M. Federico 
The reticulin stain in bone marrow biopsies — beyond marrow  fibrosis 
J. Ahluwalia,  G. Garewal,  R. Das and K. Vaiphei 
REVIEW 
Role of the microenvironment  in chronic lymphocytic leukaemia 
I’. Caligaris-Cappio
Volume  Contents 
HISTORICAL  REVIEW 
Louis Diamond and his contribution to haematology 
W. C. Mentzer 
HAEMATOLOGICAL  MALIGNANCY 
Long-term follow-up of relapsed childhood acute lymphoblastic leukaemia 
J. M. Chessells,  P. Veys, H. Kempski,  P. Henley, A. Leiper, D. Webb and I. M. Hann 
Adult T-cell leukaemia/lymphoma-like human T-cell leukaemia virus-1 replication 
in infective dermatitis 
A.-S. Gabet, M. Kazanji, P. Couppie, E. Clity, J.-F. Pouliquen, D. Sainte-Marie, C. Aznar 
and E. Wattel 
Evidence for allelic evolution of C/EBPalpha mutations in acute myeloid 
leukaemia 
J. Tiesmeier,  A. Czwalinna,  C. Muiiller-Tidow,  J. Krauter,  H. Serve, G. Heil, A. Ganser 
and W. Verbeek 
Identification of the CD33-related Siglec receptor, Siglec-5 (CD170),  as a useful 
marker in both normal myelopoiesis and acute myeloid leukaemias 
P. Virgo, P. A. Denning-Kendall, C. L. Erickson-Miller,  S. Singha, R. Evely, J. M. Hows 
and S. D. Freeman 
Progenitor cell involvement is predictive of response to induction chemotherapy in 
paediatric acute myeloid leukaemia 
D. L. Johnston, S. Meshinchi, K. E. Opheim, M. G. Pallavicini, J. Feusner, W. G. Woods, 
B. J. Lange, J. P. Radich and I. D. Bernstein 
Single agent thalidomide in patients with relapsed or refractory  acute myeloid 
leukaemia 
D. A. Thomas, E. Estey, F. J. Giles, S. Faderl, ]. Cortes, M. Keating, S. O’Brien, M. Albitar 
and H. Kantarjian 
Double Philadelphia masquerading as chromosome  20q deletion - a new 
recurrent abnormality in chronic myeloid leukaemia blast crisis 
A. G. Reid, S. Swanton,  C. Grace,  L. J. Campbell,  A. R. Green and E. P. Nacheva 
Together with the United Kingdom Cancer Cytogenetics Group (UKCCG) 
HLA-DR4 predicts haematological response to cyclosporine in T-large granular 
lymphocyte lymphoproliferative disorders 
M. Battiwalla, J]. Melenhorst, Y. Saunthararajah, R. Nakamura, J]. Molldrem, N. S. Young 
and A. J. Barrett 
'SEDG positron emission tomography versus *7Ga scintigraphy as prognostic test 
during chemotherapy for non-Hodgkin’s lymphoma 
]. M. Zijlstra, O. S. Hoekstra, P. G. H. M. Raijmakers, E. F. I. Comans, J. J. M. van der 
Hoeven, G. J. J. Teule, A. R. Jonkhoff, H. v Tinteren, A. A. Lammertsmanad  P. C. Huijgens 
The clinical impact of expert pathological review on lymphoma management:  a 
regional experience 
]. F. Lester, S. D. Dojcinov, R. L. Attanoos, C. J. O'Brien,  T. S. Maughan, E. T. Toy and 
C. H. Poynton 
Short reports  Bi-allelic silencing of the Fanconi anaemia gene FANCF in acute myeloid 
leukaemia 
M. Tischkowitz,  N. Ameziane,  Q. Waisfisz,  J. P. De Winter,  R. Harris,  T. Taniguchi, 
A. D'Andrea,  S. V. Hodgson,  C. G. Mathew and H. Joenje 
The polycythaemia rubra vera-1  gene is constitutively expressed by bone marrow 
cells and does not discriminate polycythaemia vera from reactive and other 
chronic myeloproliferative disorders 
O. Bock, E. Serinséz,  M. Neusch,  J. Schluée and H. Kreipe
Volume  Contents 
Frequent aberrant promoter hypermethylation of O°-methylguanine-DNA 
methyltransferase and death-associated protein kinase genes in immunodefi- 
ciency-related lymphomas 
D. Rossi, G. Gaidano, A. Gloghini, C. Deambrogi, S. Franceschetti, E. Berra, M. Cerri, 
C. Vendramin, A. Conconi, A. Viglio, G. Muti, P. Oreste, E. Morra, M. Paulli, D. Capello 
and A. Carbone 
TRANSPLANTATION 
Mobilization of Ph chromosome-negative peripheral blood stem cells in chronic 
myeloid leukaemia patients with imatinib mesylate-induced complete cytogenetic 
remission 
M. W. Drummond, D. Marin, R. E. Clark, J. L. Byrne, T. L. Holyoake and A. Lennard on 
behalf of the United Kingdom Chronic Myeloid Leukaemia  (UK CML)  Working Party 
Survival after relapse following tandem autotransplants in multiple myeloma 
patients: the University of Arkansas total therapy I experience 
A. B.-T.  Fassas,  B. Barlogie, §. Ward, S. Jagannath,  D. Vesole, S. Mattox,  D. Siegel, 
F. Muwalla,  M. Zangari, E. Anaissie,  F. V. Rhee, R. Thertulien,  C.-K. Lee, R. Desikan, 
V. Arzumanian,  J. Mccoy and G. Tricot 
PLATELETS,  HAEMOSTASIS  AND  THROMBOSIS 
Is the determination of anti-beta2 glycoprotein I antibodies useful in patients with 
venous thromboembolism without the antiphospholipid syndrome? 
K. Hsieh, P. Knébl, C. Rintelen, P. A. Kyrle, P. Quehenberger, C. Bialonczyk, H. Partsch, 
K. Lechner and I. Pabinger 
Factor V 1359T: a novel mutation associated with thrombosis and resistance to 
activated protein C 
A. D. Mumford, J. H. McVey, C. V. Morse,  K. Gomez,  M. Steen,  E. A. Norstrom, 
E. G. D. Tuddenham,  B. Dahlback and P. H. B. Bolton-Maggs 
Long-term safety and feasibility of arteriovenous fistulae as vascular accesses in 
children with haemophilia: a prospective study 
E. Santagostino,  A. Gringeri,  L. Berardinelli,  C. Beretta,  M. Muca-Perja and 
P. M. Mannucci 
Central venous catheter related thrombosis in haematology patients and 
prediction of risk by screening with Doppler-ultrasound 
C. J. van Rooden, F. R. Rosendaal, R. M. Y. Barge, J. A. van Oostayen, F. J. M. van der 
Meer, A. Edo Meinders and M. V. Huisman 
Increased risk for vascular complications in PRV-1  positive patients with essential 
thrombocythaemia 
P. Johansson,  A. Ricksten,  L. Wennstrém,  L. Palmqvist, J. Kutti and B. Andréasson 
Long-term evaluation of 164 patients with essential thrombocythaemia  treated 
with pipobroman: occurrence of leukaemic evolution 
V. De Sanctis,  M. G. Mazzucconi,  A. Spadea,  M. Alfo, M. Mancini,  L. Bizzoni,  M. 
Peraino and F. Mandelli 
Endothelial cell activation  in thrombotic thrombocytopenic purpura (TTP): a 
prospective analysis 
T. Romani de Wit, R. Fijnheer,  H.-J. Brinkman,  S. Kersting,  R. J]. Hene and 
J. A. van Mourik