Table Of ContentBreast Cancer Research and Treatment 26: 299-300,  1993. 
© 1993 Kluwer Academic Publishers.  Printed in the Netherlands. 
Author  index,  Volume  26 
Adkins  D  S-3  Dunphy F  S-3  Kinishita  K  67 
Allred  DC  191, 225  Kitagawa H  67 
Amadori  D  7  Eckhardt  S  41  Kodama  H  55 
Azavedo  E  207  Elledge RM  191, 225  Koenders  PG  289 
Elliott  RL  77  Kornek G  49 
Ballerini  P  1  Elton  RA  89  Krieg SL  191 
Bélanger A  253  Encarnacion  C  237  Kwasny  W  49 
Bearman  SI  S-11,  S-19 
Benedix  MG  191  Ferrari  L  1  Labrie  F  253 
Benraad ThJ  289  Fioravanti  L  275  Lehrer SP  175 
Benz CC  181  Franco  RS  217  Lei Y  163 
Berland  E  283  Fuqua SAW  117,  191, 225,  LeMaistre  CF  S-1 
Bezwoda  WR  247  237  Lepage M  253 
Bolla M  283  Lewin  A  101 
Brandt  ME  15  Greene  GL  191  Lekeso 
Brufman  G  101  LiS  253 
Haider K  49  Lower EE  217 
Cappelletti  V  7, 275  HamertonJ  149  Luce  MC  181 
Chambaz  EM  283  Harada T  55 
Chedin  M  283  Head JF  77  Marron-Charriere  J 
Chetty U  89  Hennequin  E  267  Martelo OJ  217 
Ciocca DR  237  Hill  BT  23  Martinetti  A  1 
Clark GM  225, 237  Holm  L-E  207  Matthes  S  S-11 
CétéJ  253  Horwitz  KB  119  McCoy JL  77 
Colonna  M  283  McGuire  WL  191, 
Coradini  C  275  Ichinose  Y  55  zat 
Correale  M  7  Mérand  Y  253 
Covey DF  15  Jack W  89  Meyers S  S-11, S-19 
Jardillier J-C  267  Miksicek  RJ  163 
Daidone  MG  7  Jiang S-Y  139  Miller MA  217 
Dajee D  247  Jones RB  S-11,  S-19  Miller WR  89 
de Goeij CCJ  289  Jones RJ  S-31  Miodini  P  275 
Delvincourt  C  267  Jordan  VC  139  MiyazakiI  67 
Depisch D  49  Mizukami  Y  67 
Di Fronzo G  7, 275  Kahan Z  41  Montgomery  PA  181 
Dolci  S  1  Kan N  55  Mor-YosefS  101 
Dorembus  D  101  Kaufmann  M  181  Moriguchi  Y  55 
Dotzlaw  H  149  Kennedy MJ  S-31  Murphy LC  149 
Duca P  1  Kienhuis CBM  289 
Dufton C  S-11  Kinami  S  67  Nawaz Z  191
300  Author index,  Vol. 26 
Nilsson  B_  207  Rochefort  H  107  Svane G  207 
Noguchi  M  67  Rostaing-Puissant  B  283  Sziics  M  41 
Nordevang  E  207  Ruedl  C  275 
Takamura  H  67 
Satoh  K  55  Thomas  M  67 
O’Malley  BW  191 
Schachter  BS  175  Thorpe S  107 
Ohgaki K  55 
Scheithauer  W  49 
Oriana S  1 
Schenk  T  49  Ulrich  SJ  95 
Osborne CK  237 
Schmutzler  RK  175  Uziely  B  101 
SchwarzJ  149 
Paradiso A  7 
Schweitzer  M  95  Velasquez  W  S-3 
Parker CJ  139 
Scott GK  181  Veneroni  S  7 
Parker MG  131  SecretoG   |  Venturelli  E  1 
Petruska  P  S-3 
Seymour L  247  Vescernyés  M  41 
Pirker R  49 
Shpall EJ  S-11, S-19 
Pourny C  267 
Shyamala G  95  Wang Y  163 
Puett D  15 
Silvestrini  R  7, 275  Watson  DMA  89 
Pujol P  225 
Sluyser M  289  Whelan  RDH  23 
Purdy M  S-19 
Souvignet C  283  Williams  SF  S-25 
Spencer V  S-3 
Rabin JM  175  Spitzer G  S-3  Yamasaki  S  55 
Ravdin  PM  110  Stemmer SM _ S-11,  S-19 
Riccobon  A  7  Sugie T  55  Zimniski  SJ  15
Breast Cancer Research and Treatment 26: 301-305,  1993. 
© 1993 Kluwer Academic Publishers.  Printed in the Netherlands. 
Subject  index,  Volume  26 
4-hydroperoxycyclophosphamide  induction  of autologous GVHD and antitumor 
in marrow  purging  S-19-—S-23  activity S-31-S-40 
preparative drug regimens  S-3—S-9 
adoptive immunotherapy 
for liver metastases  55-65  cathepsin  D 
alternative  splicing  as a prognostic factor (discussion)  107-111 
and estrogen  receptor exon-skipping  variants  immunohistochemical  determination  and other 
163-174  prognostic factors  7-13 
and estrogen  receptor variants  149-161  CD34+  selection 
amifostine  accelerated  marrow  engraftment  S-19—S-23 
in marrow  purging  S-19-S-23  chemotherapy 
aneuploidy  dose-intensive  (minisymposium)  S-1—S-40 
see ploidy  mdrl  gene expression  in primary vs.  metastatic 
antiestrogens  tumors  267-274 
ER point mutation  changes structure-function  navelbine  and mitomycin C in second  line 
relationship  139-147  treatment  49-53 
pure steroidal  antiestrogens and ER dimerization  pharmacokinetics at high doses  S-11—S-17 
and half-life  131-137  pharmacokinetics  in directing drug dosing 
responses,  and estrogen  receptor variants  117-  S-11-S-17 
118  tandem  non-cross-resistant  combinations 
see also tamoxifen  S-3-S-9 
aromatase  inhibitors  cisplatin 
10-propargylestr-4-ene-3,17-dione  in rat DMBA  BCNU  toxicity increase at high doses 
tumors  15-21  S-11-S-17 
autologous  bone marrow  support  in tandem  non-cross  resistant chemotherapy 
see bone marrow  transplantation  combinations  S-3—S-9 
autologous  tumor killing activity  cyclic AMP binding proteins 
in immuno-chemotherapy  for liver metastases  and prognosis  89-94 
55-65  cyclophosphamide 
in mobilizing peripheral  blood progenitor cells 
B-lymphocyte  responses  S-25-S-29 
to pokeweed mitogen and tumor antigens in  in tandem  non-cross  resistant chemotherapy 
breast cancer patients  77-88  combinations  S-3—S-9 
BCNU  pharmacokinetic  interactions  at high doses 
toxicity  increase  by high-dose cisplatin  S-11-S-17 
S-11-S-17  to augment  immunotherapy  response  55-65 
bone marrow  transplantation  cyclosporine  A 
accelerated  engraftment  with G-CSF, purging,  induction  of GVHD and antitumor activity 
and CD34+ selection  S-19-S-23  S-31-S-40
302  Subject index,  Vol. 26 
cytoxan  estrogen receptor (cont.) 
see cyclophosphamide  association  with hsp90 levels  95-100 
by both ligand binding and immunohisto- 
Depo-Provera (medroxyprogesterone  acetate,  MPA)  chemistry,  in tamoxifen  resistance  237-246 
controlled release  MPA, inhibition  of DMBA rat  dimerization,  half-life, and pure antiestrogens 
mammary  tumors  253-265  131-137 
diet  exon-skipping  variants  163-174 
fat intake and mammographic  parenchymal  genetic polymorphism associated  with spon- 
pattern  207-215  taneous abortion  175-180 
DMBA rat mammary  tumors  loss in drug but not X-ray induced drug resis- 
regression by a new  aromatase  inhibitor  15-21  tance  23-39 
DNA ploidy  non-DNA-binding  but immunoreactive  variants 
see ploidy  in breast tumors  181-189 
dose-intensive  therapy  point mutation  changes antiestrogen structure- 
in breast cancer (minisymposium)  S-1—S-40  function  relationship  139-147 
drug resistance  possible variants in ER+/PgR— breast tumors 
mdrl  gene expression in primary vs. metastatic  191-202 
tumors  267-274  truncated  variants and alternative  splicing  149- 
X-ray vs. drug induced resistance  patterns  in  161 
MCF-7 cells  23-39  variants  in ER-positive and nominally ER- 
negative cell lines  163-174 
EGF receptor  estrogen response element 
downregulation  by ER in hormone dependent  non-binding ER variants in breast tumors  181- 
tumors  289-295  189 
inverse correlation  with EGF-like activity in  tumor protease activity mimicking non-DNA- 
tumor specimens  41-47  binding ER  191-202 
endocrine therapy  etoposide 
controlled release  MPA, inhibition of DMBA  rat  in tandem non-cross  resistant chemotherapy 
mammary  tumors  253-265  combinations  S-3-S-9 
regression of rat DMBA tumors  by a new 
aromatase  inhibitor  15-21 
fat intake 
resistance  and molecular variants of ER and PR 
and mammographic  parenchymal  pattern  207- 
119-130 
ZS 
tamoxifen  resistance  vs. true ER status  237-246 
endometrium 
proliferative changes with long-term tamoxifen  G-CSF 
101-105  accelerated engraftment of hematopoietic pro- 
epidermal growth factor  genitor cells  S-19-S-23 
see EGF  in mobilizing peripheral blood progenitor cells 
estrogen receptor  S-25-S-29 
abnormalities  in breast cancer (special issue)  graft-versus-host disease (GVHD) 
117-202  induction  and antitumor activity  S-31—-S-40 
and EGF receptor in hormone dependent vs.  growth factors 
independent tumors  289-295  paracrine interactions between  hormone 
and immunohistochemical  localization of  dependent and independent cell lines  275- 
cathepsin D  7-13  281
Subject index,  Vol. 26  303 
heat shock proteins  interferon  gamma 
hsp27 loss in drug but not X-ray induced drug  augmentation of GVHD  induction  and antitumor 
resistance  23-39  activity  S-31-S-40 
hsp90 associated  with estrogen  receptor  95-100  interleukin-2 
Helix pomatia lectin (HPA)  in immuno-chemotherapy  for liver metastases 
binding as a prognostic factor  67-75  55-65 
hematopoietic  cell support 
see bone marrow,  peripheral blood stem cells 
keoxifene  (antiestrogen) 
high-dose chemotherapy 
ER point mutation changes structure-function 
in breast cancer (minisymposium)  S-1—S-40 
relationship  139-147 
hormone dependence 
and EGF receptor levels  289-295 
paracrine interactions  of dependent and indepen- 
LINE-1  sequences 
dent cell lines  275-281 
in alternatively  spliced ER variants  149-161 
hormone  resistance 
lymphocyte responses 
and molecular variants  of ER and PR  119-130 
to tumor antigens and general stimulators  in 
ER point mutation changes antiestrogen 
breast cancer patients  77-88 
structure-function  relationship  139-147 
vs.  ER status  by both ligand binding and 
immunohistochemistry  237-246  mammographic  parenchymal pattern 
HPA  and dietary fat intake  207-215 
see  Helix pomatia lectin binding  marrow  purging 
4-hydroperoxycyclophosphamide  4-hydroperoxycyclophosphamide/amifostine 
in marrow  purging  S-19-S-23  treatment  S-19-S-23 
MCF-7 cells 
ICI  164384  drug vs. X-ray induced drug resistance  patterns 
pure antiestrogens and ER dimerization  and half-  23-39 
life  131-137  mdrl  gene 
ICI  182780  expression  in primary vs. metastatic  tumors 
pure antiestrogens and ER dimerization  and half-  267-274 
life  131-137  medroxyprogesterone  acetate  (MPA) 
IGF-I  (insulin-like  growth factor I)  controlled  release  MPA, inhibition of DMBA rat 
and paracrine interactions  between  hormone  mammary  tumors  253-265 
dependent and independent cell lines  275-  microspheres,  poly[DL-lactide-co-glycolide] 
281  controlled  release  MPA, inhibition  of DMBA rat 
immuno-chemotherapy  mammary  tumors  253-265 
for liver metastases —  immunological  mitomycin C 
parameters  55-65  and navelbine  in second  line treatment  49-53 
immunohistochemistry  mitoxantrone 
quantitative cathepsin  D, vs. other prognostic  in tandem non-cross  resistant chemotherapy 
factors  7-13  combinations  S-3—S-9 
immunological  parameters  mixed lymphocyte tumor reaction 
in patients with primary breast cancer  vs.  liver  in immuno-chemotherapy  for liver metastases 
metastases  55-65  55-65 
lymphocyte responses  in breast cancer patients  molecular variants 
77-88  estrogen receptor (special issue)  117-202
304  Subject index, Vol. 26 
multidrug resistance  (MDR)  progestin resistance 
mdrl  gene expression in primary vs. metastatic  and molecular variants of ER and PR  119-130 
tumors  267-274  progestin therapy 
see also drug resistance  controlled  release  MPA, inhibition  of DMBA rat 
mammary  tumors  253-265 
natural  killer cell activity  prognostic factors 
in immuno-chemotherapy  for liver metastases  cathepsin D, by immunohistochemistry  7-13 
55-65  cathepsin D (discussion)  107-111 
navelbine  cyclic AMP binding proteins  89-94 
and mitomycin C in second  line treatment  49-  EGF receptor vs.  EGF-like  activity in tumor 
53  specimens  41-47 
nodal status  Helix pomatia \ectin binding  67-75 
and Helix pomatia lectin binding  67-75  p53 gene alterations  225-235 
phosphotyrosine  and tyrosine kinase  217-224 
OK-432 (streptococcal  immune stimulant)  platelet derived growth factor in tumor  247-252 
in immuno-chemotherapy  for liver metastases  tyrosine kinase activity  283-287 
55-65  urinary testosterone  1-6 
proliferative rate 
P-glycoprotein  by thymidine labelling, and cathepsin D  7-13 
see drug resistance  protein tyrosine kinase 
p53  see tyrosine kinase 
gene alterations and prognosis  225-235  pS2 
paracrine interactions  loss in drug-induced but not X-ray-induced drug 
co-culture of hormone dependent and indepen-  resistance  23-39 
dent cell lines  275-281  pulmonary toxicity 
peripheral blood lymphocytes  and high-dose drug interactions  S-11—S-17 
in immuno-chemotherapy  for liver metastases  purging 
55-65  4-hydroperoxycyclophosphamide/amifostine 
peripheral blood progenitor cells  treatment  of marrow  S-19-S-23 
in reconstitution  after high-dose chemotherapy 
S-25-S-29 
recurrence 
pharmacokinetics 
urinary testosterone  as a marker  1-6 
high-dose interactions of cisplatin and BCNU 
recurrence  risk 
S-11-S-17 
see prognostic factors 
phosphotyrosine 
RNA splicing 
elevation  in breast cancer,  by immunohisto- 
and estrogen receptor variants  117-118 
chemistry  217-224 
RU 39,411  (antiestrogen) 
platelet derived growth factor (PDGF) 
ER point mutation changes structure-function 
in tumor tissue, vs. prognosis  247-252 
relationship  139-147 
ploidy 
and Helix pomatia lectin binding, nodal status 
67-75  single-stranded conformation  polymorphism analysis 
progesterone  receptor  p53 gene alterations and prognosis  225-235 
and hsp90 levels  95-100  splicing variants 
isoforms, antagonists, and function  127-128  estrogen receptor and LINE-1  sequences  149- 
status  in hormone resistant tumors  237-246  161
Subject index,  Vol. 26 
spontaneous abortion  thiotepa 
association  with estrogen  receptor genetic  in tandem non-cross  resistant chemotherapy 
polymorphism  175-180  combinations  S-3—S-9 
stem cell transplantation  toxicity 
preparative drug regimens  S-3-—S-9  and pharmacokinetics at high doses  S-11—S-17 
stem cells  tumor antigens 
accelerated engraftment by CD34+ selection  T- and B-lymphocyte responses  in breast cancer 
S-19-S-23  patients  77-88 
tyrosine kinase 
T-cell growth factor  activity and prognosis  283-287 
in immuno-chemotherapy  for liver metastases  elevation  in breast cancer  217-224 
55-65 
T-lymphocyte  responses 
ultrasound 
to phytohemagglutinin  and tumor antigens in 
in evaluation of endometrial  changes with long- 
breast cancer  patients  77-88 
term  tamoxifen  101-105 
tamoxifen 
urinary markers 
and endometrial  proliferative changes  101-105 
testosterone  and recurrence  risk  1-6 
ER point mutation changes structure-function 
relationship  139-147 
VP-16 
resistance  and molecular variants of ER and PR 
see etoposide 
119-130 
resistance  and true ER status  237-246 
testosterone  WR-2721 
prognostic factor in urine  1-6  see amifostine 
TGFa (transforming growth factor alpha) 
and paracrine interactions  between hormone  ZR-75-1  cells 
dependent and independent cell lines  275-  drug vs.  X-ray induced drug resistance  patterns 
281  23-39