Biology of the Arterial Wall

283 Pages·1999·6.782 MB·English

by  Bernard I. Levy, Alain Tedgui (auth.), Bernard I. Levy, Alain Tedgui (eds.)

BIOLOGY OF THE ARTERIAL WALL
BASIC SCIENCE FOR THE CARDIOLOGIST
1. B. Levy, A. Tedgui (eds.): Biology ofthe Arterial Wall
1999 ISBN 0-7923-8458-X
-
KLC~WERA CADEMIC PUBLISHERS DORDRECHT/BOSTON/LONDON
Biology of the Arterial Wall
edited by
Bernard I. Levy
and
Alain Tedgui
INSERM U747
Lariboisiere hospital
Paris, France
Distributors for North, Central and South America:
Kluwer Academic Publishers
101 Philip Drive
Assinippi Park
Norwell, Massachusetts 0206 1 USA
Distributors for all other countries:
Kluwer Academic Publishers Group
Distribution Centre
Post Office Box 322
3300 AH Dordrecht, THE NETHERLANDS
Library of Congress Cataloging-in-Publication Data
Biology of the arterial wall 1 edited by Bernard I. Levy and Alain
Tedgui.
--
p. cm. (Basic science for the cardiologist ; 1)
Includes index.
ISBN 0-7923-8458'-X
1. Arteries--Physiology. 2. Arteries--Pathophysiology. I. LCvy,
Bernard I. 11. Tedgui, Alain. 111. Series.
[DNLM: 1. Arteries--physiology. 2. Arteries--pathology. WG 5 10
B615 19991
QP106.2.BS6 1999
612. 1'33--dc21
DNLM/DLC 98-55059
for Library of Congress CIP
Copyright 0 1999 by Kluwer Academic Publishers
All rights reserved. No part of this publication may be reproduced, stored in a
retrieval system or transmitted in any form or by any means, mechanical, photo-
copying, recording, or otherwise, without the prior written permission of the
publisher, Kluwer Academic Publishers, 101 Philip Drive, Assinippi Park, Norwell,
Massachusetts 0206 1
Printed on acid-free paper
Printed in the United States of America
Dedicated to Jacques Maclouf
Contents
List of Contributors IX
Preface
Bernard I. Levy and Alain Tedgui ............................................. Xlll
I. The Vascular Wall under Physiological Conditions
I.M orphologic aspects of the large artery vascular wall
Bernard I. Levy and Alain Tedgui ................................................ 3
2. Mechanics of the large artery vascular wall
Bernard I. Levy .......................................................................... 13
3. Neurohumoral control of the vascular system
Stephane Laurent ...................................................................... 25
4. Endothelial function and dysfunction
Paul Vanhoutte and Chantal Boulanger ..................................... 49
5. Mechanical factors and vascular biology
Alain Tedgui, Stephanie Lehoux and Bernard I. Levy ................. 71
6. Angiogenic growth factors
Cedric J. Gaultier and Jean-Baptiste Mchel ............................ 101
7. Angiogenesis
Hany A.J. Struijker Boudier, Fmnk R. M. Stassen and
Ferdinand A. C. le Noble... ......................................................... 11 5
8. Vascular aging
Jolil Belmin ............................................................................. 129
II. The Vascular Wall under Pathological Conditions .......... 149
9. Vessel and inflammation
Catherine Bernard ..................................................................... 151
10. Apoptosis in normal and pathological vessels
Ziad Mallat and Alain Tedgui.. .................................................... 193
11 . Stiffness of wall material in human hypertension
MichelE.Safar ......................................................................... 275
12. Pathobiology of atherosclerosis
Alain Tedgui. Catherine Bernard and Ziad Mallat ...................... 235
13. Arterial gene transfer
Laumnt J . Feldman and Ph . Gabriel Steg ................................ 259
Index ........................................................................................ 275
List of Contributors
Joel BELMIN, M.D.
Department of Gerontology
Hdpital Rene-Bigotini
Sevran, France
Vascular Aging
Catherine BERNARD, M.D., Ph.D.
Department of Anesthesiology
Hapital Lariboisiere
Paris, France
Vessel and Inflammation
Atherosclerosis
Chantal BOULANGER, Ph.D.
INSERM U141
Hdpital Lariboisiere
Paris, France
Endothelial Function and Dysfunction
Cedric J. GAULTIER, M.D.
INSERM U460 Remodelage cardiovasculaire
Facult6 de Medecine X. Bichat
Paris, France
Angiogenic Growth Factors
Laurent J. FELDMAN, M.D., Ph.D.
Cardiology Department
HGpital Bichat
Paris, France
Arterial Gene Tansfer
Stephane LAURENT, M.D., Ph.0.
Department of Pharmacology
Hdpital Broussais
Paris, France
Neurohumoral Control of the Vascular System
Stephanie LEHOUX, Ph.D.
INSERM U141
Hgpital Lariboisitire
Paris, France
Mechanical Factors and Vascular Biology
Bernard I. LEW, M.D., Ph.D.
INSERM U141
Hdpital Lariboisiere
Paris, France
Morphologic Aspects of the Large Artery Vascular Wall
Mechanics of the Large Artery Vascular Wall
Mechanical Factors and Vascular Biology
Ferdinand A.C. le NOBLE, Ph.D.
Department of Pharmacology, Cardiovascular Research Institute
Maastricht (CARIM)
Maastricht, The Netherlands
Ang iogenesis
Ziad MALLAT, M.D.
INSERM U141
Hdpital Lariboisiere
Paris, France
Apoptosis in the Vascular System
Atherosclerosis
Jean-Baptiste MICHEL, M.D., Ph.D.
INSERM U460 Remodelage cardiovasculaire
Faculte de MBdecine X. Bichat
Paris, France
Angiogenic Growth Factors
Michel SAFAR, M.D.
Medecine Interne I
Hdpital Broussais
Paris, France
Stiffness of Wall Material in Human Hypertension
Frank R.M. STASSEN, Ph.D.
Department of Pharmacology, Cardiovascular Research lnstitute
Maastricht (CARIM)
Maastricht, The Netherlands
Angiogenesis
Ph. Gabriel STEG, M.D., Ph.D.
Cardiology Department
Hdpital Bichat
Paris, France
Arterial Gene Tansfer
Harry STRUIJKER-BOUDIER, Ph.D.
Department of Pharmacology, Cardiovascular Research Institute
Maastricht (CARIM)
Maastricht, The Netherlands
Angiogenesis
Alain TEDGUI, Ph.D.
INSERM U141
H8pital Lariboisiere
Paris, France
Morphologic Aspects of the Large Artery Vascular Wall
Mechanical Factors and Vascular Biology
Apoptosis in normal and pathological vessels Atherosclerosis
Paul VANHOUTTE, M.D., Ph.D.
IRIS
Courbevoie , France
Endothelial Function and Dysfunction