Table Of ContentDover, G. A. Observing development through evolutionary eyes:
A practical approach 281
Author Index Downward, J. Regulatory mechanisms for ras proteins 177
Drake, J. W. Mutation rates 137
Duboule, D. The vertebrate limb: A model system to study the
Hox/HOM gene network during development and evolution
375
Dupont, G. and Goldbeter, A. Oscillations and waves of
Abbott, C. M. See Darling, S. M. cytosolic calcium: Insights from theoretical models 485
Adinolfi, M., Stone, S. and Moralli, D. Carrier detection of Dziegielewska, K. M. See Brown, W. M.
deletions in female relatives of X-linked disorders by non-
isotopic in situ hybridisation 421 Easteal, S. A mammalian molecular clock? 415
Adler, P. N. The genetic control of tissue polarity in Drosophila Edgar, L. G. Genes controlling specific cell fates in C. elegans
735 embryos 705
Albertini, D. F. Regulation of meiotic maturation in the Emmons, S. W. From cell fates to morphology: Developmental
mammalian oocyte: Interplay between exogenous cues and the genetics of the Caenorhabditis elegans male tail 309
microtubule cytoskeleton 97 Engels, W. R. The origin of P elements in Drosophila
Arkhipova, I. R. and Ilyin, Y. V. Control of transcription of melanogaster 681
Drosophila retrotransposons 161 Epstein, H. Polycomb and friends 411
Estelle, M. The plant hormone auxin: Insight in sight 439
Baldock, R., Bard, J., Kaufman, M. and Davidson, D. A real
mouse for your computer 501 Filbin, M. T. and Tennekoon, G. I. Myelin Po-protein, more
Bard, J. See Baldock, R. than just a structural protein? 541
Benbow, R. M., Zhao, J. and Larson, D. D. On the nature of Fincham, J. R. S. Boris Ephrussi - His work in genetics 347
origins of DNA replication in eukaryotes 661 Finlay, C. A. p53 loss of function: Implications for the processes
Bertrand-Garcia, R. See Freeling, M. of immortalization and tumorigenesis 557
Blow, J. A protein complex present at origins of DNA replication Freeling, M., Bertrand-Garcia, R. and Sinha, N. Maize mutants
in yeast cells 561 and variants altering developmental time and their
Blundell, T. See Murray-Rust, J. heterochronic interactions 227
Boswell, D. R. See Lesk, A. M. Furlong, R. A. The biology of hepatocyte growth factor/scatter
Bradbury, E. M. Reversible histone modifications and the factor 613
chromosome cell cycle 9
Brown, M. C. See Perry, V. H. Garrod, D. R. See Legan, P. K.
Brown, W. M., Saunders, N. R., Mollgard, K. and Goate, A. See Crawford, F.
Dziegielewska, K. M. Fetuin - an old friend revisited 749 Gober, J. W. Compartmentalized transcription and the
Burchell, A. The molecular basis of the type | glycogen storage establishment of cell type during sporulation in Bacillus subtilis
diseases 395 125
Burger, M. M. See Rusciano, D. Goldbeter, A. See Dupont, G.
Burridge, K. See Chrzanowska-Wodnicka, M. Golden, A. and Sternberg, P. W. The roles of SH2/SH3 domains
in nematode development 481
Campbell, R. D. See Milner, C. M. Goll, D. E., Thompson, V. F., Taylor, R. G. and Zalewska, T.
Cavener, D. R. Transgenic animal studies on the evolution of Is calpain activity regulated by membranes and autolysis or by
genetic regulatory circuitries 237 calcium and calpastatin? 549
Chrispeels, M. J. See Vitale, A. Gorbsky, G. J. Chromosome motion in mitosis 73
Chrzanowska-Wodnicka, M. and Burridge, K. Rho, rac and the Gould, S. J. Ontogeny and phylogeny - Revisited and reunited
actin cytoskeleton 777 275
Collins, J. E. See Legan, P. K. Gruss, C. and Sogo, J. M. Chromatin replication |
Crawford, F. and Goate, A. Alzheimer’s disease untangled 727
Creighton, T. E. Protein folding pathways determined using Hamlin, J. L. Mammalian origins of replication 651
disulphide bonds 195 Handel, M. A. and Hunt, P. A. Sex-chromosome pairing and
Cross, F. R. See Hirsch, J. P. activity during mammalian meiosis 817
Cummings, R. D. and Smith, D. F. The selectin family of Hardie, D. G. and MacKintosh, R. W. AMP-activated protein
carbohydrate-binding proteins: Structure and importance of kinase - an archetypal protein kinase cascade? 699
carbohydrate ligands for cell adhesion 849 Harris, E. See Treisman, J.
Hayes, J. J. and Wolffe, A. P. The interaction of transcription
Darling, S. M. and Abbott, C. M. Mouse models of human factors with nucleosomal DNA 597
single gene disorders: I Non-transgenic mice 359 Heitman, J. How the EcoRI endonuclease recognizes and cleaves
Davidson, D. See Baldock, R. DNA 445
Dawid, I. B. Mesoderm induction and axis determination in Hellung-Larsen, P. See Leick, V.
Xenopus laevis 687 Henneberry, R. C. Cloning of the genes for excitatory amino
De Loof, A. All animals develop from a blastula: Consequences acid receptors 465
of an undervalued definition for thinking on development 573 High, S. Membrane protein insertion into the endoplasmic
Desplan, C. See Treisman, J. reticulum - another channel tunnel? 535
Devine, P. L. and McKenzie, I. F. C. Mucins: Structure, Hill, H. Z. The function of melanin or six blind people examine
function, and associations with malignancy 619 an elephant 49
876 BioEssays Vol. 14, No. 12 - December 1992
Dover, G. A. Observing development through evolutionary eyes:
A practical approach 281
Author Index Downward, J. Regulatory mechanisms for ras proteins 177
Drake, J. W. Mutation rates 137
Duboule, D. The vertebrate limb: A model system to study the
Hox/HOM gene network during development and evolution
375
Dupont, G. and Goldbeter, A. Oscillations and waves of
Abbott, C. M. See Darling, S. M. cytosolic calcium: Insights from theoretical models 485
Adinolfi, M., Stone, S. and Moralli, D. Carrier detection of Dziegielewska, K. M. See Brown, W. M.
deletions in female relatives of X-linked disorders by non-
isotopic in situ hybridisation 421 Easteal, S. A mammalian molecular clock? 415
Adler, P. N. The genetic control of tissue polarity in Drosophila Edgar, L. G. Genes controlling specific cell fates in C. elegans
735 embryos 705
Albertini, D. F. Regulation of meiotic maturation in the Emmons, S. W. From cell fates to morphology: Developmental
mammalian oocyte: Interplay between exogenous cues and the genetics of the Caenorhabditis elegans male tail 309
microtubule cytoskeleton 97 Engels, W. R. The origin of P elements in Drosophila
Arkhipova, I. R. and Ilyin, Y. V. Control of transcription of melanogaster 681
Drosophila retrotransposons 161 Epstein, H. Polycomb and friends 411
Estelle, M. The plant hormone auxin: Insight in sight 439
Baldock, R., Bard, J., Kaufman, M. and Davidson, D. A real
mouse for your computer 501 Filbin, M. T. and Tennekoon, G. I. Myelin Po-protein, more
Bard, J. See Baldock, R. than just a structural protein? 541
Benbow, R. M., Zhao, J. and Larson, D. D. On the nature of Fincham, J. R. S. Boris Ephrussi - His work in genetics 347
origins of DNA replication in eukaryotes 661 Finlay, C. A. p53 loss of function: Implications for the processes
Bertrand-Garcia, R. See Freeling, M. of immortalization and tumorigenesis 557
Blow, J. A protein complex present at origins of DNA replication Freeling, M., Bertrand-Garcia, R. and Sinha, N. Maize mutants
in yeast cells 561 and variants altering developmental time and their
Blundell, T. See Murray-Rust, J. heterochronic interactions 227
Boswell, D. R. See Lesk, A. M. Furlong, R. A. The biology of hepatocyte growth factor/scatter
Bradbury, E. M. Reversible histone modifications and the factor 613
chromosome cell cycle 9
Brown, M. C. See Perry, V. H. Garrod, D. R. See Legan, P. K.
Brown, W. M., Saunders, N. R., Mollgard, K. and Goate, A. See Crawford, F.
Dziegielewska, K. M. Fetuin - an old friend revisited 749 Gober, J. W. Compartmentalized transcription and the
Burchell, A. The molecular basis of the type | glycogen storage establishment of cell type during sporulation in Bacillus subtilis
diseases 395 125
Burger, M. M. See Rusciano, D. Goldbeter, A. See Dupont, G.
Burridge, K. See Chrzanowska-Wodnicka, M. Golden, A. and Sternberg, P. W. The roles of SH2/SH3 domains
in nematode development 481
Campbell, R. D. See Milner, C. M. Goll, D. E., Thompson, V. F., Taylor, R. G. and Zalewska, T.
Cavener, D. R. Transgenic animal studies on the evolution of Is calpain activity regulated by membranes and autolysis or by
genetic regulatory circuitries 237 calcium and calpastatin? 549
Chrispeels, M. J. See Vitale, A. Gorbsky, G. J. Chromosome motion in mitosis 73
Chrzanowska-Wodnicka, M. and Burridge, K. Rho, rac and the Gould, S. J. Ontogeny and phylogeny - Revisited and reunited
actin cytoskeleton 777 275
Collins, J. E. See Legan, P. K. Gruss, C. and Sogo, J. M. Chromatin replication |
Crawford, F. and Goate, A. Alzheimer’s disease untangled 727
Creighton, T. E. Protein folding pathways determined using Hamlin, J. L. Mammalian origins of replication 651
disulphide bonds 195 Handel, M. A. and Hunt, P. A. Sex-chromosome pairing and
Cross, F. R. See Hirsch, J. P. activity during mammalian meiosis 817
Cummings, R. D. and Smith, D. F. The selectin family of Hardie, D. G. and MacKintosh, R. W. AMP-activated protein
carbohydrate-binding proteins: Structure and importance of kinase - an archetypal protein kinase cascade? 699
carbohydrate ligands for cell adhesion 849 Harris, E. See Treisman, J.
Hayes, J. J. and Wolffe, A. P. The interaction of transcription
Darling, S. M. and Abbott, C. M. Mouse models of human factors with nucleosomal DNA 597
single gene disorders: I Non-transgenic mice 359 Heitman, J. How the EcoRI endonuclease recognizes and cleaves
Davidson, D. See Baldock, R. DNA 445
Dawid, I. B. Mesoderm induction and axis determination in Hellung-Larsen, P. See Leick, V.
Xenopus laevis 687 Henneberry, R. C. Cloning of the genes for excitatory amino
De Loof, A. All animals develop from a blastula: Consequences acid receptors 465
of an undervalued definition for thinking on development 573 High, S. Membrane protein insertion into the endoplasmic
Desplan, C. See Treisman, J. reticulum - another channel tunnel? 535
Devine, P. L. and McKenzie, I. F. C. Mucins: Structure, Hill, H. Z. The function of melanin or six blind people examine
function, and associations with malignancy 619 an elephant 49
876 BioEssays Vol. 14, No. 12 - December 1992
Hirsch, J. P. and Cross, F. R. Pheromone response in yeast 367 Mathews, C. K. and Ji, J. DNA precursor asymmetries,
Hitoshi, Y. See Tominaga, A. replication fidelity, and variable genome evolution 295
Hodgkin, J. Genetic sex determination mechanisms and evolution Matrisian, L. M. The matrix-degrading metalloproteinases 455
253 McKenzie, I. F. C. See Devine, P. L.
Holdener-Kenny, B., Sharan, S. K and Magnuson, T. Mouse McLeod, A. N. See Murray-Rust, J.
albino deletions: From genetics to genes in development 831 Merlie, J. P. See Phillips, W. D.
Holder, N. See Maden, M. Merrill, G. F., Morgan, B. A., Lowndes, N. F. and Johnston, L.
Holland, P. W. H. Homeobox genes in vertebrate evolution 267 H. DNA synthesis control in yeast: An evolutionarily
Hsu, T. C. My favorite cytological subject: Chromosomes 785 conserved mechanism for regulating DNA synthesis genes?
Hughes, C., Stanley, P. and Koronakis, V. E.coli hemolysin 823
interactions with prokaryotic and eukaryotic cell membranes Metcalf, D. The hemopoietic regulators - An embarrassment of
519 riches 799
Hunt, P. A. See Handel, M. A. Milner, C. M. and Campbell, R. D. Genes, genes and more
genes in the human major histocompatibility complex 565
Ilyin, Y. V. See Arkhipova, I. R.
Mollgard, K. See Brown, W. M.
Mommaerts, W. F. Who discovered actin? 57
Jeffery, W. R. and Swalla, B. J. Evolution of alternate modes of
Moralli, D. See Adinolfi, M.
development in ascidians 219
Morgan, B. A. See Merrill, G. F.
Ji, J. See Mathews, C. K.
Morgan, J. E. and Partridge, T. A. Cell transplantation and gene
Johnston, L. H. See Merrill, G. F.
therapy in muscular dystrophy 641
Jones, A. M. and Prasad, P. V. Auxin-binding proteins and their
Morris, R. Thy-1, the enigmatic extrovert on the neuronal
possible roles in auxin-mediated plant cell growth 43
surface. 715
Jones, P. A., Rideout, W. M., Shen, J. C., Spruck, C. H. and
Mouritsen, O. G. and Jérgensen, K. Dynamic lipid-bilayer
Tsai, Y. L. Methylation, mutation and cancer 33
heterogeneity: A mesoscopic vehicle for membrane function?
Jorgensen, K. See Mouritsen, O. G.
129
Murray-Rust, J., McLeod, A. N., Blundell, T. and Wood, S. P.
Kaufman, M. See Baldock, R.
Structure and evolution of insulins: Implications for receptor
Koronakis, V. See Hughes, C.
binding 325
Ko, M. S. H. Induction mechanism of a single gene molecule:
Stochastic or deterministic 341
Neupert, W. See Wienhues, U.
Krumlauf, R. Evolution of the vertebrate Hox homeobox genes
Newell, P. C. and Liu, G. Streamer F mutants and chemotaxis of
245
Dictyostelium 473
Kubli, E. The sex-peptide 779
Nislow, C. See Kuriyama, R.
Kunkel, T. A. Biological asymmetries and the fidelity of
eukaryotic DNA replication 303
O’Donnell, M. Accessory protein function in the DNA
Kuriyama, R. and Nislow, C. Molecular components of the
polymerase III holoenzyme from E. coli 105
mitotic spindle 81
Kurland, C. G. Evolution of mitochondrial genomes and the
Partridge, T. A. See Morgan, J. E.
genetic code 709
Perry, V. H. and Brown, M. C. Role of macrophages in
Laird-Offringa, I. A. What determines the instability of c-myc peripheral nerve degeneration and repair 401
proto-oncogene mMRNA? 119 Phillips, W. D. and Merlie, J. P. Recombinant neuromuscular
Larson, D. D. See Benbow, R. M. synapses 671
Lasko, P. F. Molecular movements in oocyte patterning and pole Plasterk, R. H. A. Reverse genetics of Caenorhabditis elegans
cell differentiation 507 629
Leckie, B. J. High blood pressure: hunting the genes 37 Pouliot, Y. Phylogenetic analysis of the cadherin superfamily
Legan, P. K., Collins, J. E. and Garrod, D. R. The molecular 743
biology of desmosomes and hemidesmosomes: ‘What’s in a Poulton, J. Mitochondrial DNA and genetic disease 763
name?’ 385 Prasad, P. V. See Jones, A. M.
Leick, V. and Hellung-Larsen, P. Chemosensory behaviour of Pratt, W. B. Control of steroid receptor function and
Tetrahymena 61 cytoplasmic-nuclear transport by heat shock proteins 841
Lesk, A. M. and Boswell, D. R. Does protein structure determine Prescott, D. M. Cutting, splicing, reordering and elimination of
amino acid sequence? 407 DNA sequences in hypotrichous ciliates 317
Liu, G. See Newell, P. C. Price, J. See Williams, B. P.
Lowndes, N. F. See Merrill, G. F.
Lutz, R. J. See Sinensky, M. Raff, R. A. Direct-developing sea urchins and the evolutionary
reorganization of early development 211
MacKintosh, R. W. See Hardie, D. G. Reiter, R. J. The aging pineal gland and its physiological
Maden, M. and Holder, N. Retinoic acid and development of the consequences 169
central nervous system 431 Reuter, G. and Spierer, P. Position-effect variegation and
Magnuson, T. See Holdener-Kenny, B. chromatin proteins 605
Maher, J. L. DNA triple-helix formation: An approach to Rideout, W. M. See Jones, P. A.
artificial gene repressors? 807 Rusciano, D. and Burger, M. M. Why do cancer cells
Maloney, P. C. The molecular and cell biology of anion transport metastasize into particular organs? 185
by bacteria 757 Rushlow, C. and Warrior, R. The rel family of proteins 89
BioEssays Vol. 14, No. 12-December 1992 877
Saunders, N. R. See Brown, W. M. Treisman, J., Harris, E., Wilson, D. and Desplan, C. The
Schmid, S. L. The mechanism of receptor-mediated endocytosis: homeodomain: A new face for the helix-turn-helix? 145
More questions than answers 589 Tronche, F. and Yaniv, M. HNF1, a homeoprotein member of
Shapiro, J. A. Barbara McClintock, 1902-1992 791 the hepatic transcription regulatory network 579
Sharan, S. K See Holdener-Kenny, B. Tsai, Y. L. See Jones, P. A.
Shen, J. C. See Jones, P. A. Tucker, J. The microtubule-organizing centre 861
Sinensky, M. and Lutz, R. J. The prenylation of proteins 25
Sinha, N. See Freeling, M. Ullman, A. Complementation in B-galactosidase: From protein
Sleigh, M. J. Differentiation and proliferation in mouse structure to genetic engineering 201
embryonal carcinoma cells 769
Smith, D. F. See Cummings, R. D. Vitale, A. and Chrispeels, M. J. Sorting of proteins to the
Sogo, J. M. See Gruss, C. vacuoles of plant cells 151
Sommerville, J. RNA-binding proteins: Masking proteins
revealed 337 Wahle, E. The end of the message: 3’-end processing leading to
Spierer, P. See Reuter, G. polyadenylated messenger MRNA 113
Spruck, C. H. See Jones, P. A. Warrior, R. See Rushlow, C.
Stanley, P. See Hughes, C. Weiss, M. C. Contributions of Boris Ephrussi to the development
Steinman-Zwicky, M. How do germ cells choose their sex? of somatic cell genetics 349
Drosophila as a paradigm 513 Wienhues, U. and Neupert, W. Protein translocation across
Sternberg, P. W. See Golden, A. mitochondrial membranes 17
Stone, S. See Adinolfi, M. Wilkins, A. S. Hydra moves! 67
Sullivan, N. F. and Willis, A. E. Cancer predisposition in Wilkins, A. S. Evolution and development: Crete, 14-20 October
Bloom’s syndrome 333 289
Swalla, B. J. See Jeffery, W. R. Wilkins, A. S. Evolution and development: a thematic issue 209
Szybalski, W. Use of the HPRT gene and the HAT selection Wilkins, A. S. Origins of the gonadal mesoderm in Drosophila
technique in DNA-mediated transformation of mammalian 627
cells: First steps toward developing hybridoma techniques and Wilkins, A. S. Evolving ideas in development: A variety of
gene therapy 495 perspectives 869
Williams, B. P. and Price, J. What have tissue culture studies
Takaki, S. See Tominaga, A. told us about the development of oligodendrocytes? 693
Takatsu, K. See Tominaga, A. Willis, A. E. See Sullivan, N. F.
Tautz, T. Redundancies, development and the flow of Wilson, D. See Treisman, J.
information 263 Wolffe, A. P. See Hayes, J. J.
Taylor, R. G. See Goll, D. E. Wood, S. P. See Murray-Rust, J.
Tennekoon, G. I. See Filbin, M. T. Wood, W. B. Assembly of a complex bacteriophage in vitro 635
Thompson, V. F. See Goll, D. E. aaa re ‘ha E
Tominaga, A., Takaki, S., Hitoshi, Y. and Takatsu, K. Role of Re toe CaF
interleukin 5 receptor system in hematopoiesis: Molecular Zalewska, T. See Goll, D. E.
basis for overlapping function of cytokines 527 Zhao, J. See Benbow, R. M.
878 BioEssays Vol. 14, No. 12 - December 1992
Chromatin replication 1.
On the nature of origins of DNA replication in eukaryotes 661.
Subject Index Ascidian development
Evolution of alternate modes of development in ascidians 219.
Astrocytes
What have tissue culture studies told us about the development
of oligodendrocytes? 693.
Auxins
Acetylcholine receptors (AChRs) Auxin-binding proteins and their possible roles in auxin-
Recombinant neuromuscular synapses 671. mediated plant cell growth 43.
Actin The plant hormone auxin: Insight in sight 439.
Rho, rac and the actin cytoskeleton 777.
The genetic control of tissue polarity in Drosophila 735.
Who discovered actin? 57. Bacterial metabolism
Actin genes The molecular and cell biology of anion transport by bacteria
Direct-developing sea urchins and the evolutionary tah
reorganization of early development 211. Bacteriophage T4
Activin Assembly of a complex bacteriophage in vitro 635.
Mesoderm induction and axis determination in Xenopus laevis DNA precursor asymmetries, replication fidelity, and variable
687. genome evolution 295.
Acylation Behaviour
E.coli hemolysin interactions with prokaryotic and eukaryotic The sex-peptide 779.
cell membranes 519. Bithorax complex
Adaptor proteins Origins of the gonadal mesoderm in Drosophila 627.
The mechanism of receptor-mediated endocytosis: More Position-effect variegation and chromatin proteins 605.
questions than answers 589. Bloom’s syndrome
Adhesion molecules Cancer predisposition in Bloom’s syndrome 333.
Myelin Po-protein, more than just a structural protein? 541. Bombyx mori
Ageing How do germ cells choose their sex? Drosophila as a paradigm
The aging pineal gland and its physiological consequences 169. 513.
Aggregulons
Evolution and development: Crete, 14-20 October 289.
Ca*+-binding sites
Albino deletions
Mouse albino deletions: From genetics to genes in Is calpain activity regulated by membranes and autolysis or by
development 831. calcium and calpastatin? 549.
Cadherin
Alchohol dehydrogenase
Transgenic animal studies on the evolution of genetic Phylogenetic analysis of the cadherin superfamily 743.
regulatory circuitries 237. The molecular biology of desmosomes and hemidesmosomes:
Alzheimer’s Disease “What’s in a name?’ 385.
Alzheimer’s disease untangled 727. Caenorhabditis elegans
amber mutants From cell fates to morphology: Developmental genetics of the
Assembly of a complex bacteriophage in vitro 635. Caenorhabditis elegans male tail 309.
Amoebal aggregation Genes controlling specific cell fates in C. elegans embryos 705.
Streamer F mutants and chemotaxis of Dictyostelium 473. Genetic sex determination mechanisms and evolution 253.
AMP.-activated protein kinases Redundancies, development and the flow of information 263.
AMP-activated protein kinase - an archetypal protein kinase Reverse genetics of Caenorhabditis elegans 629.
cascade? 699. The roles of SH2/SH3 domains in nematode development 481.
6-Amyloid Calcium
Alzheimer’s disease untangled 727. Oscillations and waves of cytosolic calcium: Insights from
Anaesthetics theoretical models 485.
Dynamic lipid-bilayer heterogeneity: A mesoscopic vehicle for Calpain
membrane function? 129. Is calpain activity regulated by membranes and autolysis or by
Angiotensin calcium and calpastatin? 549.
High blood pressure: hunting the genes 37. Calpastatin
Anion exchange Is calpain activity regulated by membranes and autolysis or by
The molecular and cell biology of anion transport by bacteria calcium and calpastatin? 549.
TS Cancer
ou- Antitrypsin Cancer predisposition in Bloom’s syndrome 333.
Transgenic animal studies on the evolution of genetic Methylation, mutation and cancer 33.
regulatory circuitries 237. Mucins: Structure, function, and associations with malignancy
Arabidopsis 619. ‘
The plant hormone auxin: Insight in sight 439. p53 loss of function: Implications for the processes of
ARS elements immortalization and tumorigenesis 557.
A protein complex present at origins of DNA replication in The function of melanin or six blind people examine an
yeast cells 561. elephant 49.
BioEssays Vol. 14,No.12-December 1992 879
Why do cancer cells metastasize into particular organs? 185. Cell movement
cdc2 kinase Rho, rac and the actin cytoskeleton 777.
Regulation of meiotic maturation in the mammalian oocyte: Cell transplantation
Interplay between exogenous cues and the microtubule Cell transplantation and gene therapy in muscular dystrophy
cytoskeleton 97. 641.
Cell adhesion Cell-cell interactions
Phylogenetic analysis of the cadherin superfamily 743. Genes controlling specific cell fates in C. elegans embryos 705.
Cell adhesion molecules The selectin family of carbohydrate-binding proteins: Structure
The molecular biology of desmosomes and hemidesmosomes: and importance of carbohydrate ligands for cell adhesion
“What’s in a name?’ 385. 849.
Cell cycle Central nervous system
DNA synthesis control in yeast: An evolutionarily conserved Retinoic acid and development of the central nervous system
mechanism for regulating DNA synthesis genes? 823. 431.
Mammalian origins of replication 651. Chaperonins
Regulation of meiotic maturation in the mammalian oocyte: Control of steroid receptor function and cytoplasmic-nuclear
Interplay between exogenous cues and the microtubule transport by heat shock proteins 841.
cytoskeleton 97. Membrane protein insertion into the endoplasmic reticulum -
Reversible histone modifications and the chromosome cell another channel tunnel? 535.
Mitochondrial DNA and genetic disease 763.
cycle 9.
Cell differentiation Protein translocation across mitochondrial membranes 17.
All animals develop from a blastula: Consequences of an Chemotaxis
Chemosensory behaviour of Tetrahymena 61.
undervalued definition for thinking on development 573
Differentiation and proliferation in mouse embryonal Streamer F mutants and chemotaxis of Dictyostelium 473.
Chick development
carcinoma cells 769.
The vertebrate limb: A model system to study the Hox/HOM
HNFI1, a homeoprotein member of the hepatic transcription
gene network during development and evolution 375.
regulatory network 579.
Cholesterol
What have tissue culture studies told us about the development
Dynamic lipid-bilayer heterogeneity: A mesoscopic vehicle for
of oligodendrocytes? 693.
membrane function? 129.
Cell fate determination
Chromatin structure
From cell fates to morphology: Developmental genetics of the
Chromatin replication 1.
Caenorhabditis elegans male tail 309.
Polycomb and friends 411.
Genes controlling specific cell fates in C. elegans embryos 705.
Position-effect variegation and chromatin proteins 605.
Cell fusion
Reversible histone modifications and the chromosome cell
Use of the HPRT gene and the HAT selection technique in
cycle 9.
DNA-mediated transformation of mammalian cells: First
Sex-chromosome pairing and activity during mammalian
steps toward developing hybridoma techniques and gene
meiosis 817.
therapy 495.
The interaction of transcription factors with nucleosomal DNA
Cell growth
597.
p53 loss of function: Implications for the processes of
Chromosome movement
immortalization and tumorigenesis 557.
Chromosome motion in mitosis 73.
The biology of hepatocyte growth factor/scatter factor 613. Molecular components of the mitotic spindle 81.
Thy-1, the enigmatic extrovert on the neuronal surface 715. Chromosomes
Cell lineage My favorite cytological subject: Chromosomes 785.
Direct-developing sea urchins and the evolutionary Cilia
reorganization of early development 211. Chemosensory behaviour of Tetrahymena 61.
Evolution of alternate modes of development in ascidians 219. Ciliates
From cell fates to morphology: Developmental genetics of the Cutting, splicing, reordering and elimination of DNA sequences
Caenorhabditis elegans male tail 309. in hypotrichous ciliates 317.
Genes controlling specific cell fates in C. elegans embryos 705. Circadian rhythms
What have tissue culture studies told us about the development The aging pineal gland and its physiological consequences 169.
of oligodendrocytes? 693. Clathrin
Cell membranes The mechanism of receptor-mediated endocytosis: More
Auxin-binding proteins and their possible roles in auxin- questions than answers 589.
mediated plant cell growth 43. Cleavage
Dynamic lipid-bilayer heterogeneity: A mesoscopic vehicle for Direct-developing sea urchins and the evolutionary
membrane function? 129. reorganization of early development 211.
E.coli hemolysin interactions with prokaryotic and eukaryotic Coated pits
cell membranes 519. The mechanism of receptor-mediated endocytosis: More
Membrane protein insertion into the endoplasmic reticulum - questions than answers 589.
another channel tunnel? 535. Codon usage
Cell motility Evolution of mitochondrial genomes and the genetic code 709.
The biology of hepatocyte growth factor/scatter factor 613. Collagen
Why do cancer cells metastasize into particular organs? 185. The matrix-degrading metalloproteinases 455.
880 BioEssays Vol. 14, No. 12 - December 1992
Colony stimulating factors (CSF) DNA rearrangements
The hemopoietic regulators - An embarrassment of riches 799. Cancer predisposition in Bloom’s syndrome 333.
Co-evolution Cutting, splicing, reordering and elimination of DNA sequences
Observing development through evolutionary eyes: A practical in hypotrichous ciliates 317.
approach 281. DNA replication
a-crystallin gene A protein complex present at origins of DNA replication in
Mouse models of human single gene disorders: I Non- yeast cells 561.
transgenic mice 359. Accessory protein function in the DNA polymerase III
Cyclic AMP holoenzyme from E. coli 105.
Streamer F mutants and chemotaxis of Dictyostelium 473. Biological asymmetries and the fidelity of eukaryotic DNA
Cyclic GMP replication 303.
Streamer F mutants and chemotaxis of Dictyostelium 473. Chromatin replication 1.
Cytokines DNA precursor asymmetries, replication fidelity, and variable
Role of interleukin 5 receptor system in hematopoiesis: genome evolution 295.
Molecular basis for overlapping function of cytokines 527. DNA synthesis control in yeast: An evolutionarily conserved
The matrix-degrading metalloproteinases 455. mechanism for regulating DNA synthesis genes? 823.
Cytoskeleton Mammalian origins of replication 651.
All animals develop from a blastula: Consequences of an My favorite cytological subject: Chromosomes 785.
undervalued definition for thinking on development 573 On the nature of origins of DNA replication in eukaryotes 661.
Control of steroid receptor function and cytoplasmic-nuclear DNA structure
transport by heat shock proteins 841. DNA triple-helix formation: An approach to artificial gene
Molecular movements in oocyte patterning and pole cell repressors? 807.
differentiation 507. On the nature of origins of DNA replication in eukaryotes 661.
Reversible histone modifications and the chromosome cell
Recombinant neuromuscular synapses 671.
cycle 9.
Rho, rac and the actin cytoskeleton 777.
The interaction of transcription factors with nucleosomal DNA
Streamer F mutants and chemotaxis of Dictyostelium 473.
597.
The microtubule-organizing centre 861.
DNA transformation
C-jun
Use of the HPRT gene and the HAT selection technique in
Differentiation and proliferation in mouse embryonal
DNA-mediated transformation of mammalian cells: First
carcinoma cells 769.
steps toward developing hybridoma techniques and gene
c-met
therapy 495.
The biology of hepatocyte growth factor/scatter factor 613.
dorsal
The rel family of proteins 89.
Darwin, Charles
Dosage compensation
Ontogeny and phylogeny - Revisited and reunited 275.
Genetic sex determination mechanisms and evolution 253.
Databases
Drosophila
Does protein structure determine amino acid sequence? 407.
Boris Ephrussi - His work in genetics 347.
Deoxnucleotide triphosphate (ANTP) pools
Cloning of the genes for excitatory amino acid receptors 465.
Biological asymmetries and the fidelity of eukaryotic DNA
Control of transcription of Drosophila retrotransposons 161.
replication 303.
Evolution of the vertebrate Hox homeobox genes 245.
DNA precursor asymmetries, replication fidelity, and variable Genetic sex determination mechanisms and evolution 253.
genome evolution 295. Homeobox genes in vertebrate evolution 267.
Desmosomes How do germ cells choose their sex? Drosophila as a paradigm
The molecular biology of desmosomes and hemidesmosomes: S13.
‘What’s in a name?’ 385. Molecular movements in oocyte patterning and pole cell
Development - Reconstruction of databases differentiation 507.
A real mouse for your computer 501. Observing development through evolutionary eyes: A practical
Dictyostelium discoideum approach 281.
Streamer F mutants and chemotaxis of Dictyostelium 473. Origins of the gonadal mesoderm in Drosophila 627.
Dihydrofalate reductase (DAFR) Polycomb and friends 411.
Mammalian origins of replication 651. Position-effect variegation and chromatin proteins 605.
Disulphide bonds Redundancies, development and the flow of information 263.
Protein folding pathways determined using disulphide bonds The genetic control of tissue polarity in Drosophila 735.
195. The homeodomain: A new face for the helix-turn-helix? 145.
DNA binding proteins The microtubule-organizing centre 861.
DNA triple-helix formation: An approach to artificial gene The origin of P elements in Drosophila melanogaster 681.
repressors? 807. The rel family of proteins 89.
DNA polymerase The sex-peptide 779.
Accessory protein function in the DNA polymerase III Transgenic animal studies on the evolution of genetic
holoenzyme from E. coli 105. regulatory circuitries 237.
Biological asymmetries and the fidelity of eukaryotic DNA Drug metabolism
replication 303. The function of melanin or six blind people examine an
Mutation rates 137. elephant 49.
BioEssays Vol. 14, No. 12-December1992 881
Dystrophin Evolution of alternate modes of development in ascidians 219.
Cell transplantation and gene therapy in muscular dystrophy Evolution of mitochondrial genomes and the genetic code 709.
641. Evolution of the vertebrate Hox homeobox genes 245.
Mouse models of human single gene disorders: I Non- Genetic sex determination mechanisms and evolution 253.
transgenic mice 359. Maize mutants and variants altering developmental time and
their heterochronic interactions 227.
Egg structure Mutation rates 137.
Evolution of alternate modes of development in ascidians 219. Observing development through evolutionary eyes: A practical
Embryonal carcinoma cells approach 281.
Differentiation and proliferation in mouse embryonal Ontogeny and phylogeny - Revisited and reunited 275.
carcinoma cells 769. Redundancies, development and the flow of information 263.
Embryonic axes The origin of P elements in Drosophila melanogaster 681.
Mesoderm induction and axis determination in Xenopus laevis
Transgenic animal studies on the evolution of genetic
687.
regulaiory circuitries 237.
Embryonic development
Excitotoxic hypothesis
Direct-developing sea urchins and the evolutionary
Cloning of the genes for excitatory amino acid receptors 465.
reorganization of early development 211.
Extracellular matrix (ECM)
Evolution of alternate modes of development in ascidians 219.
The matrix-degrading metalloproteinases 455.
Homeobox genes in vertebrate evolution 267.
Endocytosis
Fate-mapping
The mechanism of receptor-mediated endocytosis: More
Origins of the gonadal mesoderm in Drosophila 627.
questions than answers 589.
Fatty acid synthesis
Endoplasmic reticulum
Auxin-binding proteins and their possible roles in auxin- AMP-activated protein kinase - an archetypal protein kinase
mediated plant cell growth 43. cascade? 699.
Membrane protein insertion into the endoplasmic reticulum - Fetal development
another channel tunnel? 535. Fetuin - an old friend revisited 749.
Sorting of proteins to the vacuoles of plant cells 151. Fetuin
Endothelial cells Fetuin - an old friend revisited 749.
Why do cancer cells metastasize into particular organs? 185. Fibroblast cells
Enzyme induction Recombinant neuromuscular synapses 671.
Induction mechanism of a single gene molecule: Stochastic or Flowering
deterministic 341. Maize mutants and variants altering developmental time and
Enzyme-substrate interactions their heterochronic interactions 227.
How the EcoRI endonuclease recognizes and cleaves DNA Francois, Jacob
445. Complementation in B-galactosidase: From protein structure to
Epithelia genetic engineering 201.
All animals develop from a blastula: Consequences of an Contributions of Boris Ephrussi to the development of somatic
undervalued definition for thinking on development 573 cell genetics 349.
Ephrussi, Boris Evolution and development: a thematic issue 209.
Boris Ephrussi - His work in genetics 347. Functional redundancy
Contributions of Boris Ephrussi to the development of somatic Redundancies, development and the flow of information 263.
cell genetics 349.
Escherichia coli G proteins
Accessory protein function in the DNA polymerase III
Pheromone response in yeast 367.
holoenzyme from E. coli 105.
f-galactosidase
Complementation in B-galactosidase: From protein structure to
Complementation in B-galactosidase: From protein structure to
genetic engineering 201.
genetic engineering 201.
How the EcoRI endonuclease recognizes and cleaves DNA
Induction mechanism of a single gene molecule: Stochastic or
445.
deterministic 341.
On the nature of origins of DNA replication in eukaryotes 661.
Gene density
Protein translocation across mitochondrial membranes 17.
The molecular and cell biology of anion transport by bacteria Genes, genes and more genes in the human major
73) histocompatibility complex 565.
E.coli hemolysin interactions with prokaryotic and eukaryotic Gene structure
cell membranes 519. Control of transcription of Drosophila retrotransposons 161.
Evolution Fetuin - an old friend revisited 749.
A mammalian molecular clock? 415. Mitochondrial DNA and genetic disease 763.
AMP.-activated protein kinase - an archetypal protein kinase Mucins: Structure, function, and associations with malignancy
cascade? 699. 619.
Direct-developing sea urchins and the evolutionary Phylogenetic analysis of the cadherin superfamily 743.
reorganization of early development 211. The genetic control of tissue polarity in Drosophila 735.
Evolution and development: Crete, 14-20 October 289. Gene targeting
Evolution and development: a thematic issue 209. Reverse genetics of Caenorhabditis elegans 629.
882 BioEssays Vol. 14, No. 12 - December 1992
Gene therapy The molecular biology of desmosomes and hemidesmosomes:
Cell transplantation and gene therapy in muscular dystrophy “What’s in a name?’ 385.
641. Goldschmidt, Richard
Genetic code Maize mutants and variants altering developmental time and
Evolution of mitochondrial genomes and the genetic code 709. their heterochronic interactions 227.
Genetic complementation Gonadal mesoderm
Complementation in B-galactosidase: From protein structure to Origins of the gonadal mesoderm in Drosophila 627.
genetic engineering 201. goosecoid
Genetic defects Mesoderm induction and axis determination in Xenopus laevis
Alzheimer’s disease untangled 727. 687.
Cancer predisposition in Bloom’s syndrome 333. Granulocyte colony stimulating factors (GCSF)
High blood pressure: hunting the genes 37. The hemopoietic regulators - An embarrassment of riches 799.
Methylation, mutation and cancer 33. Growth
Mitochondrial DNA and genetic disease 763. Why do cancer cells metastasize into particular organs? 185.
Mouse albino deletions: From genetics to genes in Growth factors
development 831. The hemopoietic regulators - An embarrassment of riches 799.
Mouse models of human single gene disorders: I Non- GTPases
transgenic mice 359. Regulatory mechanisms for ras proteins 177.
The molecular basis of the type | glycogen storage diseases
395. Haeckel, Ernst
Genetic recombination Direct-developing sea urchins and the evolutionary
Sex-chromosome pairing and activity during mammalian reorganization of early development 211.
meiosis 817. Ontogeny and phylogeny - Revisited and reunited 275.
The origin of P elements in Drosophila melanogaster 681. Harris, Henry
Genome mapping Contributions of Boris Ephrussi to the development of somatic
Alzheimer’s disease untangled 727. cell genetics 349.
Carrier detection of deletions in female relatives of X-linked HAT selection technique
disorders by non-isotopic in situ hybridisation 421. Use of the HPRT gene and the HAT selection technique in
Genes, genes and more genes in the human major DNA-mediated transformation of mammalian cells: First
histocompatibility complex 565. steps toward developing hybridoma techniques and gene
High blood pressure: hunting the genes 37. therapy 495.
Mouse albino deletions: From genetics to genes in Heat shock proteins
development 831. Control of steroid receptor function and cytoplasmic-nuclear
Mouse models of human single gene disorders: I Non- transport by heat shock proteins 841.
transgenic mice 359. Hematopoiesis
Genome structure Role of interleukin 5 receptor system in hematopoiesis:
Biological asymmetries and the fidelity of eukaryotic DNA Molecular basis for overlapping function of cytokines 527.
replication 303. Hemidesmosomes
Cutting, splicing, reordering and elimination of DNA sequences The molecular biology of desmosomes and hemidesmosomes:
in hypotrichous ciliates 317. ‘What’s in a name?’ 385.
DNA precursor asymmetries, replication fidelity, and variable Hemoglobin
genome evolution 295. Does protein structure determine amino acid sequence? 407.
Genomic imprinting Hemolysin
Imprintor or imprinted 857. E.coli hemolysin interactions with prokaryotic and eukaryotic
Germ line development cell membranes 519.
How do germ cells choose their sex? Drosophila as a paradigm Hemopoiesis
513. The hemopoietic regulators - An embarrassment of riches 799.
Molecular movements in oocyte patterning and pole cell Hepatic nuclear factor (HNF)
differentiation 507. HNFI, a homeoprotein member of the hepatic transcription
Sex-chromosome pairing and activity during mammalian regulatory network 579.
meiosis 817. Hepatocyte growth factor
Glucocorticoid receptor The biology of hepatocyte growth factor/scatter factor 613.
The interaction of transcription factors with nucleosomal DNA Heterochromatin
597. My favorite cytological subject: Chromosomes 785.
Glucose-6-phosphatase Position-effect variegation and chromatin proteins 605.
The molecular basis of the type | glycogen storage diseases Heterochrony
395. Direct-developing sea urchins and the evolutionary
Glutamine reorganization of early development 211.
Cloning of the genes for excitatory amino acid receptors 465. Evolution and development: Crete, 14-20 October 289.
Glycogen Evolution and development: a thematic issue 209.
The molecular basis of the type | glycogen storage diseases Evolution of alternate modes of development in ascidians 219.
395. Maize mutants and variants altering developmental time and
Glycoproteins their heterochronic interactions 227.
Fetuin - an old friend revisited 749. Ontogeny and phylogeny - Revisited and reunited 275.
BioEssays Vol. 14, No. 12-December 1992 883
Histones In situ hybridisation
Chromatin replication 1. Carrier detection of deletions in female relatives of X-linked
Reversible histone modifications and the chromosome cell disorders by non-isotopic in situ hybridisation 421.
cycle 9. Induction
History of ideas Evolving ideas in development: A variety of perspectives 869.
Evolving ideas in development: A variety of perspectives 869. Inositol phosphatides
HIV Oscillations and waves of cytosolic calcium: Insights from
RNA-binding proteins: Masking proteins revealed 337. theoretical models 485.
HMG-CoA reductase Insulin receptor
AMP.-activated protein kinase - an archetypal protein kinase Structure and evolution of insulins: Implications for receptor
binding 325.
cascade? 699.
Integrins
Homeobox genes
The molecular biology of desmosomes and hemidesmosomes:
Evolution of the vertebrate Hox homeobox genes 245.
“What’s in a name?’ 385.
Homeobox genes in vertebrate evolution 267.
Interleukin 5
The vertebrate limb: A model system to study the Hox/HOM
Role of interleukin 5 receptor system in hematopoiesis:
gene network during development and evolution 375.
Molecular basis for overlapping function of cytokines 527.
Homeodomain
Interleukins
Evolution of the vertebrate Hox homeobox genes 245.
The hemopoietic regulators - An embarrassment of riches 799.
Homeodomain proteins
Intermediate filaments
HNFI, a homeoprotein member of the hepatic transcription
The molecular biology of desmosomes and hemidesmosomes:
regulatory network 579. “What’s in a name?’ 385.
The homeodomain: A new face for the helix-turn-helix? 145. Intracellular signalling
Homologous recombination Oscillations and waves of cytosolic calcium: Insights from
Reverse genetics of Caenorhabditis elegans 629. theoretical models 485.
Hox genes Intracellulose metabolism
Evolution of the vertebrate Hox homeobox genes 245. AMP-activated protein kinase - an archetypal protein kinase
Hydra moves! 67. cascade? 699.
The vertebrate limb: A model system to study the Hox/HOM Contributions of Boris Ephrussi to the development of somatic
gene network during development and evolution 375. cell genetics 349.
hsdr gene
Mouse albino deletions: From genetics to genes in Keratinocytes
development 831. The function of melanin or six blind people examine an
Human genome elephant 49.
Genes, genes and more genes in the human major Kinetochores
histocompatibility complex 565. Chromosome motion in mitosis 73.
hunch back (hb) The microtubule-organizing centre 861.
Observing development through evolutionary eyes: A practical Kruppel (kn)
approach 281. Redundancies, development and the flow of information 263.
Redundancies, development and the flow of information 263.
Hunter syndrome Larval development
Evolution of alternate modes of development in ascidians 219.
Carrier detection of deletions in female relatives of X-linked
Lectins
disorders by non-isotopic in situ hybridisation 421.
The selectin family of carbohydrate-binding proteins: Structure
Hybrid dyogenesis
and importance of carbohydrate ligands for cell adhesion
* The origin of P elements in Drosophila melanogaster 681.
849.
Hydra
Limb development
Hydra moves! 67.
The vertebrate limb: A model system to study the Hox/HOM
Hypertension
gene network during development and evolution 375.
High blood pressure: hunting the genes 37.
Lipid bilayer
Hypoxanthine-guanine phospkecribosyl transference
Dynamic lipid-bilayer heterogeneity: A mesoscopic vehicle for
Use of the HPRT gene and the HAT selection technique in membrane function? 129.
DNA-mediated transformation of mammalian cells: First Liver metabolism
steps toward developing hybridoma techniques and gene The molecular basis of the type | glycogen storage diseases
therapy 495. 395.
Lymphocytes
Immune system Role of interleukin 5 receptor system in hematopoiesis:
Role of interleukin 5 receptor system in hematopoiesis: Molecular basis for overlapping function of cytokines 527.
Molecular basis for overlapping function of cytokines 527.
Thy-1, the enigmatic extrovert on the neuronal surface 715. Macromolecular assembly
Immunoglobulin gene Assembly ofa complex bacteriophage in vitro 635.
Myelin Po-protein, more than just a structural protein? 541. Macronuclear structure
Imprinting Cutting, splicing, reordering and elimination of DNA sequences
Position-effect variegation and chromatin proteins 605. in hypotrichous ciliates 317.
884 BioEssays Vol. 14, No. 12 - December 1992
