Table Of ContentLippincott’s
Illustrated Reviews:
Biochemistr
Sixth Edition
Lippincott’s
Illustrated Reviews:
Biochemistr
Sixth Edition
Denise R. Ferrier, PhD
Professor
Department of Biochemistry and Molecular Biology
Drexel University College of Medicine
Philadelphia, Pennsylvania
Health
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Sixth Edition
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9 8 7 6 5 4 3 2 1
Library of Congress Cataloging-in-Publication Data
Ferrier, Denise R.
Biochemistry / Denise R. Ferrier. -- 6th ed.
p. ; cm. -- (Lippincott’s illustrated reviews)
Rev. ed. of: Biochemistry / Richard A. Harvey, Denise R. Ferrier. 5th ed. c2011.
Includes bibliographical references and index.
ISBN 978-1-4511-7562-2 (alk. paper)
I. Title. II. Series: Lippincott’s illustrated reviews.
[DNLM: 1. Biochemistry--Examination Questions. QU 18.2]
612.3′9--dc23
2012025941
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Acknowledgments
I am grateful to my colleagues at Drexel University College of Medicine who generously
shared their expertise to help make this book as accurate and as useful to medical
students as possible. I am particularly appreciative of the many helpful comments of Dr.
Åke Rökaeus of the Karolinska Institute as they have enhanced the accuracy of this work.
In addition, the author thanks Dr. Susan K. Fried and Dr. Richard B. Horenstein for their
valuable contributions to the Obesity chapter in previous editions of this text. A special
thank you to Dr. Alan Katz for his helpful comments on the clinical aspects of the cases in
the Appendix. Ms. Barbara Engle was an invaluable sounding board throughout the
process.
The editors and production staff of Lippincott Williams & Wilkins were an important
source of encouragement. I particularly want to acknowledge the contributions of Susan
Ryner, the Acquisitions Editor, and Angela Collins, the Managing Editor. Many thanks are
due to Kelly Horvath, Development Editor, for her assistance in the final editing of this
book. I also want to thank Deborah McQuade for her work in the assembly of the 6th
edition.
This book is dedicated to my
husband John, whose loving
support made the task possible;
to my students, who have taught
me so much over the last 20
years; and to Richard Harvey and
the late Pamela Champe, who
helped me develop as an author.
Contents
UNIT I: Protein Structure and Function
Chapter 1: Amino Acids
Chapter 2: Structure of Proteins
Chapter 3: Globular Proteins
Chapter 4: Fibrous Proteins
Chapter 5: Enzymes
UNIT II: Bioenergetics and Carbohydrate Metabolism
Chapter 6: Bioenergetics and Oxidative Phosphorylation
Chapter 7: Introduction to Carbohydrates
Chapter 8: Introduction to Metabolism and Glycolysis
Chapter 9: Tricarboxylic Acid Cycle and Pyruvate Dehydrogenase Complex
Chapter 10: Gluconeogenesis
Chapter 11: Glycogen Metabolism
Chapter 12: Metabolism of Monosaccharides and Disaccharides
Chapter 13: Pentose Phosphate Pathway and Nicotinamide Adenine Dinucleotide
Phosphate
Chapter 14: Glycosaminoglycans, Proteoglycans, and Glycoproteins
UNIT III: Lipid Metabolism
Chapter 15: Dietary Lipids Metabolism
Chapter 16: Fatty Acid, Ketone Body, and Triacylglycerol Metabolism
Chapter 17: Phospholipid, Glycosphingolipid, and Eicosanoid Metabolism
Chapter 18: Cholesterol, Lipoprotein, and Steroid Metabolism
UNIT IV: Nitrogen Metabolism
Chapter 19: Amino Acids: Disposal of Nitrogen
Chapter 20: Amino Acid Degradation and Synthesis
Chapter 21: Conversion of Amino Acids to Specialized Products
Chapter 22: Nucleotide Metabolism
UNIT V: Integration of Metabolism
Chapter 23: Metabolic Effects of Insulin and Glucagon
Chapter 24: The Feed–Fast Cycle
Chapter 25: Diabetes Mellitus
Chapter 26: Obesity
Chapter 27: Nutrition
Chapter 28: Vitamins
UNIT VI: Storage and Expression of Genetic Information
Chapter 29: DNA Structure, Replication, and Repair
Chapter 30: RNA Structure, Synthesis, and Processing
Chapter 31: Protein Synthesis
Chapter 32: Regulation of Gene Expression
Chapter 33: Biotechnology and Human Disease
Appendix: Clinical Cases
Index
Bonus chapter online! Chapter 34: Blood Clotting (Use your scratch-off code
provided in the front of this book for access to this and other free online resources on
the point.)
UNIT I:
Protein Structure and Function
Amino Acids 1
