Autism and Pervasive Developmental Disorders (Cambridge Child and Adolescent Psychiatry)

357 Pages·2007·3.45 MB·English

by  Fred R. Volkmar

This page intentionally left blank
CambridgeChildandAdolescentPsychiatry
Childandadolescentpsychiatryisanimportantandgrowingareaofclinicalpsychiatry.Thelastdecade
hasseenarapidexpansionofscientificknowledgeinthisfieldandhasprovidedanewunderstandingof
theunderlyingpathologyofmentaldisordersintheseagegroups.Thisseriesisaimedatpractitioners
and researchers both in child and adolescent mental health services and developmental and clinical
neuroscience.Focusingonpsychopathology,ithighlightsthosetopicswherethegrowthofknowledge
hashadthegreatestimpactonclinicalpracticeandonthetreatmentandunderstandingofmentalillness.
Individualvolumesbenefitbothfromtheinternationalexpertiseoftheircontributorsandacoherence
generatedthroughauniformstyleandstructurefortheseries.Eachvolumeprovides,firstahistorical
overviewandacleardescriptiveaccountofthepsychopathologyofaspecificdisorderorgroupofrelated
disorders.Thesefeaturesthenformthebasisforathoroughcriticalreviewoftheetiology,naturalhistory,
management,prevention,andimpactonlateradultadjustment.Whileeachvolumeisthereforecomplete
initsownright,volumesalsorelatetoeachothertocreateaflexibleandcollectableseriesthatshould
appealtostudentsaswellasexperiencedscientistsandpractitioners.
Editorialboard
Serieseditor ProfessorIanM.Goodyer UniversityofCambridge
Associateeditors
DrRobertN.Goodman ProfessorDrHermanvanEngeland
InstituteofPsychiatry,London AcademischZiekenhuisUtrecht
ProfessorBarryNurcombe ProfessorFredR.Volkmar
TheUniversityofQueensland YaleChildStudyCenter
ProfessorDrHelmutRemschmidt
KlinikumderPhilipps-Universita¨t,Marburg,Germany
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Autism and Pervasive
Developmental
Disorders
Second edition
Editedby
Fred R. Volkmar
CAMBRIDGEUNIVERSITY PRESS
Cambridge, New York, Melbourne, Madrid, Cape Town, Singapore, São Paulo
Cambridge University Press
The Edinburgh Building, Cambridge CB28RU, UK
Published in the United States of America by Cambridge University Press, New York
www.cambridge.org
Information on this title: www.cambridge.org/9780521549578
© Cambridge University Press 2007
This publication is in copyright. Subject to statutory exception and to the provision of
relevant collective licensing agreements, no reproduction of any part may take place
without the written permission of Cambridge University Press.
First published in print format 2007
ISBN-13 978-0-511-27931-7 eBook (NetLibrary)
ISBN-10 0-511-27931-0 eBook (NetLibrary)
ISBN-13 978-0-521-54957-8 paperback
ISBN-10 0-521-54957-4 paperback
Cambridge University Press has no responsibility for the persistence or accuracy of urls
for external or third-party internet websites referred to in this publication, and does not
guarantee that any content on such websites is, or will remain, accurate or appropriate.
Cambridge University Press has no responsibility for the persistence or accuracy of URLs
for external or third-party internet websites referred to in this publication, and does not
guarantee that any content on such websites is, or will remain, accurate or appropriate.
Every effort has been made in preparing this publication to provide accurate and up-to-
date information which is in accord with accepted standards and practice at the time of
publication. Although case histories are drawn from actual cases, every effort has been
made to disguise the identities of the individuals involved. Nevertheless, the authors,
editors, and publishers can make no warranties that the information contained herein is
totally free from error, not least because clinical standards are constantly changing through
research and regulation. The authors, editors, and publishers therefore disclaim all liability
for direct or consequential damages resulting from the use of material contained in this
publication. Readers are strongly advised to pay careful attention to information provided
by the manufacturer of any drugs or equipment that they plan to use.
Contents
Listofcontributors pagevi
Prefacetothesecondedition ix
1 Diagnosisanddefinitionofautismandotherpervasive
developmentaldisorders 1
FredR.VolkmarandCatherineLord
2 Epidemiologicalsurveysofpervasivedevelopmentaldisorders 33
EricFombonne
3 Psychologicalfactorsinautism 69
MargotPriorandSallyOzonoff
4 Communicationanditsdevelopmentinautismspectrumdisorders 129
RheaPaul
5 Geneticepidemiologyofautismspectrumdisorders 157
PeterSzatmariandMarshallB.Jones
6 Theneurobiologyofautism 179
FritzPoustka
7 Psychopharmacology 221
CraigA.Erickson,KimberlyA.Stigler,DavidJ.Posey,andChristopher
J.McDougle
8 Behavioralandeducationalapproachestothepervasive
developmentaldisorders 255
SandraL.Harris
9 TheoutcomeinadultlifeforpeoplewithASD 269
PatriciaHowlin
10 Autism,socialneuroscience,andendophenotypes 307
LynnWaterhouse,DeborahFein,andEmilyG.W.Nichols
Index 337
v
Contributors
CraigA.Erickson PatriciaHowlin
DepartmentofPsychiatry DepartmentofPsychology
IndianaUniversitySchoolofMedicine InstituteofPsychiatry
1111W.10thStreet DenmarkHill
Indianapolis LondonSE58AF
IN46202-4800 UK
USA
MarshallB.Jones
DepartmentofPsychiatry
DeborahFein McMasterUniversity
234BlissHall FacultyofHealthSciences
TheCollegeofNewJersey P.O.Box850
Ewing HamiltonL8N3S5
NJ08629 Canada
USA
CatherineLord
DepartmentsofPsychology
EricFombonne
Psychiatry
DepartmentofPsychiatry
andPediatrics
MontrealChildren’sHospital
UniversityofMichiganAutismand
4018Ste.CatherineWest
CommunicativeDisordersCenter(UMACC),
Montreal
DepartmentsofPsychology,Psychiatry,and
QC,H3Z1P2
Pediatrics
Canada
AnnArbor
Michigan
SandraL.Harris USA
GraduateSchoolofAppliedandProfessional
ChristopherJ.McDougle
Psychology
DepartmentofPsychiatry
P.O.Box819
IndianaUniversitySchoolofMedicine
Rutgers
1111W.10thStreet
TheStateUniversityofNewJersey
PBA305
Piscataway
Indianapolis
NJ08855-0819
IN46202-4800
USA
USA
vi
vii Listofcontributors
EmilyG.W.Nichols MargotPrior
234BlissHall SchoolofBehaviouralSciences
TheCollegeofNewJersey UniversityofMelbourne
Ewing VIC3010
NJ08629 Australia
USA
KimberlyA.Stigler
SallyOzonoff DepartmentofPsychiatry
MINDInstituteandDepartmentof IndianaUniversitySchoolofMedicine
Psychiatry 1111W.10thStreet
UniversityofCalifornia–Davis Indianapolis
Sacramento IN46202-4800
CA95817 USA
USA
PeterSzatmari
RheaPaul OffordCentreforChildStudies
SouthernConnecticutStateUniversity McMasterUniversity
P.O.Box207900 ChedokeSite
NewHaven PattersonBldg
CT06520 Hamilton,Ontario
USA CanadaL8N3Z5
DavidJ.Posey FredR.Volkmar
DepartmentofPsychiatry ChildStudyCenter
IndianaUniversitySchoolofMedicine YaleUniversity
1111W.10thStreet P.O.Box207900
Indianapolis NewHaven
IN46202-4800 CT06520
USA USA
FritzPoustka LynnWaterhouse
DepartmentofChildandAdolescent 234BlissHall
Psychiatry TheCollegeofNewJersey
J.W.GoetheUniversity Ewing
Deutschordenstrasse50 NJ08629
D-60590Frankfurt-am-Main USA
Germany