Atlas of dermoscopy

396 Pages·2012·36.461 MB·English

Atlas of
Dermoscopy
Second Edition
Edited by
Ashfaq A. Marghoob
Josep Malvehy
Ralph P. Braun
Atlas of Dermoscopy

Atlas of Dermoscopy
Second Edition
Edited by
Ashfaq A. Marghoob, MD
Memorial Sloan-Kettering Cancer Center’s regional skin
cancer clinic, Hauppauge, New York, USA
Memorial Sloan-Kettering Cancer Center, New York City,
New York, USA
Josep Malvehy, MD
Melanoma Unit, University Hospital Clinic,
Barcelona, Spain
Ralph P. Braun, MD
Department of Dermatology, University of Zurich,
Zurich, Switzerland
Published in 2012 by Informa Healthcare, 119 Farringdon Road, London EC1R 3DA, UK.
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Dedication
To Alfred W. Kopf, mentor par excellence, who introduced me to dermoscopy and
encouraged me not to settle for mediocrity.
To Allan Halpern, a chief unmatched, for providing the opportunity and means for me to
pursue my passions and for allowing me to reach heights I could never have imagined.
To my fellows, residents, and students, for all your valuable insights, inquisitive nature, and hard
work. You have all profoundly infl uenced my career and knowledge. I will remember
each and every one of you forever!
To my children, Adam, Nadeem, Hannah, and Samir, remember to strive to do your best in all
endeavors you undertake. Always be just, kind, and loving. Remember your
Creator and thank Him every hour of every day for all that He has provided for you.
To Iman, my wife of more than 25 years, thank you for standing by my side. I could not
have journeyed so far without your love, support, help, and patience.
To my parents, Mamnoon and Monika, for your love and for providing me with the foundation
to successfully navigate through this life. To you both I owe everything!
To my sister, Azra, for always being there for me.

AA M
To my son Alexander
To my parents Ulrike und Paul, for always beeing there for us.
RPB
Contents
Contributors viii 6g Three-point checklist 134
Foreword Allan C. Halpern xx Giuseppe Argenziano
1. Introduction 1 6h Revised version of pattern analysis 138
Ashfaq A. Marghoob, Ralph P. Braun, and Josep Malvehy Harald Kittler, Cliff Rosendahl, and Alan Cameron
2. Principles of dermoscopy and dermoscopic equipment 3 7. Benign melanocytic lesions
Steven Q. Wang, Ashfaq A. Marghoob, and Alon Scope
7a Congenital melanocytic nevi 147
3. Histopathologic tissue correlations of Ashfaq A. Marghoob
dermoscopic structures 10
Ralph P. Braun, Alon Scope, Ashfaq A. Marghoob, Katrin Kerl, 7b Dysplastic (atypical) nevi 159
Harold S. Rabinovitz, and Josep Malvehy Ashfaq A. Marghoob and Alfred W. Kopf
4. Two-step algorithm: Differentiating melanocytic from 7c Banal nevi and growing nevi 171
nonmelanocytic lesions 33 Iris Zalaudek
Ashfaq A. Marghoob and Ralph P. Braun
7d Blue nevi and variants 181
5. Nonmelanocytic lesions
Cristina Carrera, Josep Malvehy, and Susana Puig
5a Basal cell carcinoma 40
7e Spitz and Reed nevi 189
Steven Q. Wang and Scott W. Menzies
Gerardo Ferrara and Giuseppe Argenziano
5b Actinic keratosis, Bowen’s disease, keratoacanthoma, 7f Recurrent (persistent) nevi 198
and squamous cell carcinoma 48
Ashfaq A. Marghoob
Iris Zalaudek, Alan Cameron, and Cliff Rosendahl
8. Melanoma
5c Solar lentigines, seborrheic keratoses, and lichen
planus-like keratosis 58 8a Superficial spreading melanoma 203
Steven Q. Wang, Harold S. Rabinovitz, Margaret C. Oliveiro, Scott W. Menzies
and Ashfaq A. Marghoob
8b Acrolentiginous melanoma 210
5d Vascular lesions 70 Josep Malvehy and Susana Puig
Pedro Zaballos, Josep Malvehy, and Susana Puig
8c Nodular melanoma 220
5e Dermatofibromas 79 Scott W. Menzies
Pedro Zaballos, Susana Puig, and Josep Malvehy
8d Lentigo maligna melanoma 223
6. Step 2: Methods to differentiate between melanoma Alon Scope, Steven Q. Wang, and Harold S. Rabinovit
and benign melanocytic nevi
8e Amelanotic and hypomelanotic melanoma 230
6a Analytic features of melanoma vs benign nevi Juergen F. Kreusch, Scott W. Menzies, and Giuseppe Argenziano
on nonglabrous skin: Colors and structures 89
Josep Malvehy and Susana Puig 8f Equivocal lesions, false positive, and false negative 235
Susana Puig, Josep Malvehy, Ashfaq A. Marghoob,
6b Pattern analysis 98 and Giuseppe Argenziano
Ashfaq A. Marghoob
8g Desmoplastic melanoma and metastatic melanoma 247
Steven Q. Wang, Natalia Jaimes-López, and Ashfaq A. Marghoob
6c ABCD rule 113
Ulrike Weigert, Walter H.C. Burgdorf, and Wilhelm Stolz
9. Special locations
6d Menzies method 118 9a Palms and soles 254
Scott W. Menzies Josep Malvehy and Susana Puig
6e Seven-point checklist and the seven rules not 9b Nails 268
to miss melanoma incognito 124
Ralph P. Braun and Luc Thomas
Giuseppe Argenziano
9c Face 276
6f CASH algorithm 131 Nancy H. Kim, Margaret C. Oliviero, Ralph P. Braun,
Jennifer A. Stein and Alfred W. Kopf Ashfaq A. Marghoob, and Harold S. Rabinovitz
vi
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CONTENTS
9d Hair and scalp (trichoscopy) 291 14. Followup of melanocytic skin lesions with
Ralph M. Trüeb, Lidia Rudnicka, Malgorzata A. Olszewska, digital dermoscopy 354
Ralph P. Braun, Isabel Kolm, and Adriana Rakowska Harald Kittler and Scott W. Menzies
9e Mucosal lesions 301 15. Teledermoscopy and computer-assisted diagnosis 362
Andreas Blum and Olga Simionescu Dougal F. Coates and H. Peter Soyer
10. Exceptions to the two-step dermoscopy algorithm 309 16. Beyond dermoscopy 366
Randie H. Kim, Natalia Jaimes-López, Elizabeth A. Quigley, Natalia Jaimes-López and Allan C. Halpern
and Ashfaq A. Marghoob
17. Concluding remarks 371
11. Dermoscopy in general dermatology 325 Ashfaq A. Marghoob and Natalia Jaimes-López
Iris Zalaudek
Index 379
12. Vascular structures 337
Ashfaq A. Marghoob and Tracey N. Liebman
13. Diagnostic accuracy of dermoscopy 351
Harald Kittler and Scott W. Menzies
Contributors
Giuseppe Argenziano Josep Malvehy
Department of Dermatology, Second University of Naples, Naples, Italy Melanoma Unit, Dermatology Department, Hospital Clinic of Barcelona,
Barcelona, Spain
Andreas Blum
Private and Teaching Practice of Dermatology, Konstanz, Germany Ashfaq A. Marghoob
Dermatology Service, Memorial Sloan-Kettering Cancer Center,
Ralph P. Braun Hauppauge, New York, USA
Department of Dermatology, University Hospital Zurich,
Zurich, Switzerland Scott W. Menzies
Department of Dermatology, Sydney Medical School, The University
Walter H.C. Burgdorf of Sydney, Sydney, New South Wales, Australia
Department of Dermatology, Ludwig Maximilian University, Munich, The Sydney Melanoma Diagnostic Centre, Sydney Cancer Center, Royal
Germany Prince Alfred Hospital, Sydney, New South Wales, Australia
Alan Cameron Margaret C. Oliviero
Brisbane, Queensland, Australia Skin and Cancer Associates, Plantation, Florida, USA
Cristina Carrera Malgorzata A. Olszewska
Dermatology Department, Hospital Clínic of Barcelona, Barcelona, Spain Department of Dermatology, Warsaw Medical University, Warsaw, Poland
Dougal F. Coates Susana Puig
Queensland Institute of Dermatology, Queensland Skin & Cancer Melanoma Unit, Dermatology Department, Hospital Clinic
Foundation, Greenslope Private Hospital, Brisbane, Queensland, of Barcelona, Barcelona, Spain
Australia
Elizabeth A. Quigley
Gerardo Ferrara Memorial Sloan-Kettering Cancer Center, New York, New York, USA
Department of Dermatology, Second University of Naples, Naples, Italy
Harold S. Rabinovitz
Allan C. Halpern Skin and Cancer Associates, Plantation, Florida, USA
Dermatology Service, Memorial Sloan-Kettering Cancer Center, New York,
New York, USA Adriana Rakowska
Department of Dermatology, CSK MSWiA, Warsaw, Poland
Natalia Jaimes-López
Memorial Sloan-Kettering Cancer Center, New York, New York, USA Cliff Rosendahl
The Skin Cancer Audit Research Database and Queensland University,
Katrin Kerl Brisbane, Queensland, Australia
Department of Dermatology, Medical University of Graz, Graz, Austria
Lidia Rudnicka
Nancy H. Kim Department of Dermatology, CSK MSWiA, Warsaw, Poland
Spectrum Dermatology, Tucson, Arizona, USA
Alon Scope
Randie H. Kim Dermatology Service, Memorial Sloan-Kettering Cancer Center, New York,
Memorial Sloan-Kettering Cancer Center, New York, New York, USA New York, USA
Harald Kittler Olga Simionescu
Department of Dermatology, Medical University of Vienna, Department of Pathology, Victor Babes National Institute of Pathology,
Vienna, Austria Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Isabel Kolm H. Peter Soyer
Department of Dermatology, University Hospital Zurich, Dermatology Research Centre, The University of Queensland,
Zurich, Switzerland School of Medicine, Princess Alexandra Hospital, Brisbane,
Queensland, Australia
Alfred W. Kopf
Professor Emeritus of Dermatology, NYU School of Medicine, Jennifer A. Stein
Lake George, New York, USA Department of Dermatology, NYU School of Medicine, New York,
New York, USA
Jürgen F. Kreusch
Lübeck, Germany Wilhelm Stolz
Department of Dermatology, Allergology, and Environmental Medicine,
Tracey N. Liebman Hospital Shwabing, Munich, Germany
Memorial Sloan-Kettering Cancer Center, New York, New York, USA Department of Dermatiology, University of Munich, Munich, Germany
viii
ix
CONTRIBUTORS
Luc Thomas Ulrike Weigert
Department of Dermatology, University Centre, Lyon, France Department of Dermatology, Medical University of Vienna,
Vienna, Austria
Ralph M. Trüeb
Department of Dermatology, University Hospital Zurich, Zurich, Pedro Zaballos
Switzerland Dermatology Department, Hospital de Sant Pau i Santa Tecla,
Tarragona, Spain
Steven Q. Wang
Dermatology Service, Memorial Sloan-Kettering Cancer Center, New York, Iris Zalaudek
New York, USA Department of Dermatology, Medical University of Graz, Graz, Austria