Download Animal Models in Disease Research: Honours Department of Pathology University of Melbourne Theo Mantamadiotis PDF Free - Full Version
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About Animal Models in Disease Research: Honours Department of Pathology University of Melbourne Theo Mantamadiotis
Animal models are commonly used in disease research. [1] Transgenic animal models allow the introduction of human genes which can provide insights into disease mechanisms. For example, APP/PS1 mice are used as an Alzheimer's disease model. [2] Gene knockout models are also used to study the effects of removing a gene. However, knockout of some critical genes can lead to embryonic lethality. [3] The Cre-loxP system allows conditional knockout to bypass this issue and study the gene's function. Proper experimental design and adherence to ethical guidelines are important when using animal models in biomedical research.
Detailed Information
| Author: | ['Riv sash'] |
|---|---|
| Publication Year: | 2017 |
| Pages: | 35 |
| Language: | English |
| Format: | |
| Price: | FREE |
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