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ALTERNATIVEAPPROACHESTOHUMANBLOODRESOURCES IN CLINICALPRACTICE DEVELOPMENTS IN HEMATOLOGYAND IMMUNOLOGY Volume 33 Thetitlespublishedinthisseriesarelistedattheendofthisvolume. Alternative Approaches to Human Blood Resources in Clinical Practice Proceedings of the Twenty-Second International Symposium on Blood Transfusion, Groningen 1997, organized by the Red Cross Blood Bank Noord Nederland edited by C. Th. SMIT SIBINGA and P. C. DAS Red Cross Blood Bank Noord Nederland, The Netherlands and J.C. FRATANTONI c.L. McIntosh & Ass., Rockville, MD, U.S.A. SPRINGER SCIENCE+BUSINESS MEDIA, B.V. A C.I.P. Catalogue record for this book is available from the Library of Congress. ISBN 978-1-4613-7571-5 ISBN 978-1-4615-5619-0 (eBook) DOI 10.1007/978-1-4615-5619-0 Printed on acid-free paper AII Rights Reserved © 1998 Springer Science+Business Media Dordrecht Originally published by Kluwer Academic Publishers in 1998 Softcover reprint of the hardcover 1s t edition 1998 No part of the material protected by this copyright notice may be reproduced or utilized in any form or by any means, electronic or mechanical, inciuding photocopying, recording or by any information storage and retrieval system, without written permission from the copyright owner Dr. ee Th. SmitSibinga Dr.10'ephC. Fratantoni Prof. Dr.10nJ. van Rood Initiatorand Organizer Chairman OpcningAddrc Baxter Acknowledgement ThispublicationhasbeenmadepossiblethroughthesupportofBaxter,which isgratefully acknowledged. VII CONTENTS ModeratorsandSpeakers XI Foreword XIII I.TheClinicalSetting: HowtoOptimiseSupportiveHaemotherapy PrinciplesofSupportiveHaemotherapy 3 W.G. vanAken WhatShouldTriggeraTransfusion? 9 W.G. Murphy TheEfficacyofTechnologiestoMinimisePeri-OperativeAllogeneic Transfusion 17 A. Laupacis Evidence-BasedTransfusionMedicineortheNeedtoEvaluateClinical Outcome 37 lTh.M. de Wolf Discussion 43 II.ChemicalandBiologicalAlternatives TheRole ofO TransportintheDevelopmentoftheTransfusionTrigger........55 2 R.M. Winslow RecombinantHumanErythropoietin- CouldItBeUsedinaBetterWay?.......75 1.T. Goodnough TheImpactofHaematopoieticGrowthFactorsonSupportiveCarein ClinicalOncology: WithSpecialAttentiontoPotentialTumourCell ContaminationintheStemCellHarvest... 81 E.G.E. deVries VIII TheDevelopmentofSynthocytesTM,aNovel PlateletSubstitute 97 S.M.Middleton RecentDevelopmentsintheConstructionofBispecificAntibodies 103 L. de Leij Re-Appraisingthe WasteStatusofBuffyCoats: Natural Human Interferon... 119 D.M.Nicolson Discussion 123 III. AlternativeApproachesinClinicalPractice Volume: AMatterofReplacement 135 P.L. Baele TheManagementofAnaemiain the Surgical Patient: What'sNew? 147 R.K. Spence HowtoSaveBlood: Alternative Approaches in Anaesthesiology andSurgery 161 A.W.M.M. Koopman-vanGernert The UseofTechnologiesto Decrease PerioperativeAllogeneic Blood Transfusion: An International SurveyofPractice 167 D. Fergusson UmbilicalCordBloodas an AlternativeSourceofHaernatopoieticStem CellsforTransplantation 175 F. Fa1kenburg CordBlood BankingandTransplantin Europe 183 V. Rocha Discussion 197 IV.The BalanceofRisks, Benefitsand Costs Indicationsfor Red BloodCellTransfusion 209 C.R. Valeri Cost-EffectivenessofConventional andAlternative Approachesin TransfusionPractice:The ValueofDecision Analysis 215 J.P. AuBuchon IX TheDesignofTransfusion in RandomisedControlledTrials inCritically III Patients 223 P.C. Hebert TheFutureofHumanBloodResources 239 J.c. Fratantoni Discussion 245 Index 253 Xl MODERATORS AND SPEAKERS Moderators J.F. Fratantoni -c.L. Mcintosh& Associates Inc., Rockville, MD, USA (chairman) P.C. Das - RedCrossBlood BankNoordNederland,Groningen,NL L.T. Goodnough - WashingtonUniversitySchoolofMedicine, St. Louis, MO, USA C.Th. SmitSibinga- Red CrossBlood BankNoordNederland,Groningen,NL C.R. Valeri - Naval Blood Research Laboratory, Boston,MS, USA H.J.C. de Wit - Red CrossBloodBankNoordNederland,Groningen,NL J.Th.M. de Wolf -Academic HospitalGroningen, Departmentof Haematology,Groningen,NL Speakers W.G. van Aken - Central LaboratoryfortheBloodTransfusionofthe Dutch Red Cross, Amsterdam, NL J.P. AuBuchon - Dartmouth-HitchcockMedical Center, Lebanon,NH, USA P.L. Baele - UniversityClinic St. Luc, DepartmentofAnaesthesiology, Brussels, B P.C. Hebert - LoebMedical Research Institute, Ottawa, Ontario,C F. Falkenburg - Eurocord FoundationNederland, Leiden, NL D. Fergusson - OttawaCivic Hospital,Clinical Epidemiology Unit, Ottawa,Ontario,C A.W.M.M. Koop - Hospital Gooi-Noord, Blaricum,NL man-vanGernert A. Laupacis - OttawaCivic Hospital,Ottawa,Ontario,C L. de Leij - AcademicHospitalGroningen, DepartmentofClinical Immunology,Groningen, NL XII W.G. Murphy - BloodTransfusionServiceBoard,Dublin,IRL D.M.Nicolson - Viragen(Scotland)Ltd.,Midlothian,UK. V. Rocha - EuropeanResearcProjectofCordBloodTransplantation, Paris,F R.K. Spence - StatenIslandUniversityHospital,StatenIsland,NY,USA E.G.E. deVries - AcademicHospitalGroningen,DepartmentofClinical Oncology,Groningen,NL R.M. Winslow - VeteransAffairsMedicalCenter,UCSanDiego, SanDiego,CA,USA Prepareddiscussant S. Middleton - AndarisLtd.,Nottingham,UK.

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Currently blood is a volatile issue. The safety of blood and the quantification of transfusion risks have been dominant themes that have stimulated the development of alternative approaches in this rapidly developing area. In clinical medicine conventional blood and its components are used in suppor

Alternative Approaches to Human Blood Resources in Clinical Practice: Proceedings of the Twenty-Second International Symposium on Blood Transfusion, Groningen 1997, organized by the Red Cross Blood Bank Noord Nederland PDF

257 Pages·1998·6.97 MB·English

by W. G. van Aken (auth.)

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Author:	W. G. van Aken (auth.)
Publication Year:	1998
Pages:	257
Language:	English
File Size:	6.97
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