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106 Pages·2014·1.91 MB·English

ALPHA ΩMEGA

ALPHA

45TH ANNUAL SCIENTIFIC
RESEARCH SYMPOSIUM

Friday, august 8, 2014
Great hall
The Mary Duke Biddle Trent Semans Center for
Health Education

ALPHA OMEGA ALPHA MEDICAL HONOR SOCIETY
45th ANNUAL SCIENTIFIC RESEARCH SYMPOSIUM

Robert J. Lefkowitz, MD
Nobel Prize in Chemistry, 2012
Investigator, Howard Hughes Medical Institute
James B. Duke Professor of Medicine
“Seven Transmembrane Receptors”
Friday, August 8, 2014
The Mary Duke Biddle Trent Semans Center for Health Education
Great Hall

7:30-8:15 AM Platform Presentation Setup
Breakfast – Served the Great Hall Lobby

8:30-10:45 AM Platform Presentations - Great Hall

***Class of 2018 arrives for the rest of the afternoon***

10:45 AM -12:30 PM Open Poster Presentations
(10:45 AM – 12:30 PM: Judging)

12:30 Pick up lunch – The Learning Hall, 2nd Floor (enter from NOSH side and exit the
room through the west entrance)

RETURN TO THE GREAT HALL FOR 1:00 PM PRESENTATIONS!

1:00 – 1:45 PM Dr. Ed Buckley and Dr. Colleen Grochowski - Curriculum Updates

1:45 – 2:00 PM Allison Webb, Nick Tsipis, and John Yerxa - The Feagin Medical Leadership Model
and the Duke Leadership, Education, and Development (LEAD) Curriculum

2:00 - 3:00 PM Keynote Address: Robert J. Lefkowitz, MD

3:00 – 3:15 PM Presentation of Awards

3:15 PM Adjourn

The Duke AΩA Chapter would like to thank the following for their
participation in today’s Symposium:

Platform Judges
Edward Buckley, M.D., Vice Dean for Education, Professor of Pediatrics

Philip Rosoff, M.D., M.A., Pediatrics-Hematology/Oncology, Medicine - Oncology

Daniel Laskowitz, M.D., MHS, Associate Professor of Medicine, Neurology; Associate Professor
of Anesthesiology & Neurobiology

Gerard Blobe, M.D., Ph.D., Professor of Medicine; Professor of Pharmacology & Cancer Biology

Joseph Lo, Ph.D., Associate Professor in the Department of Radiology

Poster Judges
Allingham, Rand, M.D., Professor of Ophthalmology; Chief of Glaucoma Service
Andolsek, Kathryn, M.D., MPH, Associate Director, Graduate Medical Education; Community and
Family Medicine.
Bagley, Carlos, M.D., Associate Professor of Surgery- Neurosurgery
Bennett, Ellen, Ph.D, Assistant Professor of Neurology
Blitzblau, Rachel, M.D., Ph.D., Assistant Professor of Radiation Oncology
Blobe, Gerard, M.D., Ph.D., Professor of Medicine; Professor of Pharmacology & Cancer Biology
Brennan, Todd, M.D., MS, Assistant Professor of Surgery- Abdominal Transplant
Challa, Pratap, M.D., Associate Professor of Ophthalmology
Chin, Bennett, M.D., Associate Professor of Radiology / Nuclear Medicine
Chino, Junzo, M.D., Assistant Professor of Radiation Oncology; Duke Cancer Institute
Chu, Vivian, M.D., MHS, Associate Professor of Medicine-Infectious Diseases
Corsino, Leonor, M.D., FACE, MHS, Assistant Professor of Medicine; Associate Chair- Department
of Medicine Minority Recruitment and Retention Committee
Crow, Jennifer, M.D., Assistant Professor of Pathology
Daubert, James, M.D., Professor of Cardiology- General Electrophysiology
Dawson, Hana, Ph.D, Assistant Professor of Neurology
Dement, John, Ph.D., Professor in Community and Family Medicine- Occupational & Envir Med-Gen
Edelman, David, M.D., Associate Professor of Medicine
Graffagnino, Carmen, M.D., Professor of Neurology; Chief- Division of Neurocritical Care Medicine;
Medical Director- Neuroscience Critical Care Unit
Guy, Cynthia, M.D., Associate Professor of Pathology
Hall, Russell P., M.D., Professor of Dermatology/ Immunology; Chair-Department of Dermatology
Hartwig, Matthew, M.D., Assistant Professor of Surgery-Cardiovascular & Thoracic
Hauser, Beth, PhD, Professor of Medical Genetics
Hayden, Kathleen, Ph.D., Associate Professor in Psychiatry and Behavioral Sciences
Inman, Brant, M.D., MS, Associate Professor of Surgery; Vice Chief of Urology
Karhausen, Jöern, M.D., Assistant Professor Anesthesiology
Kernagis, Dawn, Ph.D, Research Fellow- Brain Injury Translational Research Center at DUMC
Kim, Charles, M.D., Assistant Professor of Radiology- Vascular/Intervention Radiology
Klitzman, Bruce, Ph.D., Associate Professor of Plastic Max & Oral Surgery
Kraft, Monica, M.D., Director, Duke Asthma, Allergy, and Airway Center
Kraus, William, M.D., Professor of Medicine, Professor in the School of Nursing- Cardiology
Kwatra, Madan, Ph.D., Associate Professor in Anesthesiology, Associate Professor of Pharmacology
& Cancer Biology, Associate Professor in Psychiatry and Behavioral Sciences
Ledford, Julie, Ph.D, Assistant Professor in Medicine-Pulmonary; Assistant Research Professor in Cell
Biology
Leppert, Phyllis, M.D., Professor of Obstetrics and Gynecology
Levinson, Howard, M.D., Associate Professor of Surgery- Plastic Max & Oral Surgery
Liedtke, Wolfgang, M.D., PhD, Associate Professor of Neurology/Neurobiology/Anesthesiology
Lisanby, Holly, M.D., Chair- Department of Psychiatry & Behavioral Sciences
McFarlin, Jessica, M.D., Medical Instructor in the Department of Neurology
McNeill, Diana, M.D., Professor of Medicine- Endocrinology and Metabolism;
Obstetrics-Gynecology
Michener, James L., M.D., DTMI - Duke Center for Community Research (DCCR); Professor of
Community and Family Medicine; Clinical Professor, School of Nursing; Chair, Department of
Community and Family Medicine
Moon, Richard, M.D., Chief, Division of General, Vascular, and Transplant Anesthesia Medical;
Director, Hyperbaric Center
Nadler, Victor J., Ph.D., Professor of Pharmacology & Cancer Biology, Department of Neurobiology
Neelon, Sara, PhD, Associate Professor of Community and Family Medicine and Global Health;
Director of DGHI Postdoctoral Fellowship Program; Faculty Fellow of the Center for Child and
Family Policy
Nelson, Rendon, M.D., Reed and Martha Rice Professor of Radiology
Pappas, Theodore, M.D., Professor of Surgery- Surgical Innovation; Interim Chair- Department of
Surgery; Chief of General and Advanced Gastrointestinal Surgery; Vice Dean for Medical
Affairs
Paulson, Erik K., M.D., Chairman-Department of Radiology; Professor of Radiology
Permar, Sallie, M.D., Ph.D., Assistant Professor of Pediatrics- Infectious Diseases
Pickup, David, Ph.D., Associate Professor of Virology in the Department of Molecular Genetics and
Microbiology
Raghunathan, Karthik, M.D., MPH, Assistant Professor of Anesthesiology-VAMC Division
Rao, Vasantha, Ph.D., Associate Professor in Ophthalmology
Reiman, Robert, M.D., Assistant Professor of Radiology
Rosenberg, Paul, M.D., Associate Professor of Medicine- Cardiology
Rosoff, Philip, M.D., M.A., Pediatrics-Hematology/Oncology, Medicine - Oncology
Sangvai, Devdutta, M.D., MBA, Assistant Professor in Community and Family Medicine/Pediatrics/
Psychiatry and Behavioral Sciences; Associate Chief Medical Officer, DUHS; Medical Director,
DukeWELL
Shah, Svati, M.D., Associate Professor of Cardiology
Sidhu, Kolby, M.D., FRCPC, Associate Professor of Radiation Oncology
Silberberg, Mina, Ph.D., Associate Professor of Community and Family Medicine; Vice-Chief for
Research and Evaluation of the Division of Community Health
Smith, Brian P., M.D., MHS, MPH, Associate Professor of Pediatrics; Chief-Division of Quantitative
Sciences, Pediatrics
Stafford-Smith, Mark, M.D., Professor of Anesthesiology; Director-Adult Cardiothoracic Anesthesia
and Critical Care Fellowship; Director- Fellowship Education Program; Vice Chair-Education
Sunday, Mary, M.D., Ph.D., Professor of Pathology
White, Rebekah, M.D., Associate Professor of Surgery-Oncology
Willett, Christopher, M.D., Professor of Radiation Oncology; Member of Duke Cancer Institute;
Chair- Department of Radiation Oncology
Wolf, Matthew, M.D., Ph.D., Associate Professor of Medicine-Cardiology
Yoo, David, Ph.D., Assistant Professor of Radiation Oncology
Zafar, Syed Yousef, M.D., Associate Professor of Medicine, Member of DCRI, Member of Duke
Cancer Institute

Special Thanks
Mr. E. Arthur Palumbo , a 1949 Duke University graduate, established The Palumbo Family Medical
Scholarship which provides a full-tuition scholarship for the fourth year of medical school and will be
awarded today. Mr . Palumbo is a great friend of Duke Medicine who has also provided major funding
to Duke Children’s Hospital, and who also established The Leonard Palumbo, Jr., MD Faculty
Achievement Award in memory of his brother – a Duke University School of Medicine alumnus (MD
’44) and former Duke Obstetrics and Gynecology faculty member. The award is given annually to one
or more Duke School of Medicine faculty members who best exemplify the qualities of compassionate
patient care and dedication to teaching and mentoring young physicians that his late brother embodied.
PLATFORM
PRESENTATIONS

PLATFORM PRESENTATIONS SCHEDULE
8:30 - Bangura, Fatu
Gestational diabetes mellitus and DNA methylation in regulatory sequences of genomically
imprinted genes in the offspring
Mentor: Cathrine Hoyo, PhD, MPH
Clinical Research Study Program, Vivian Chu, MD, Director

8:40 - Irene J. Pien
Mammary Adipose Stem Cells: Evaluating Specimens from Breast Cancer Patients
Mentor: Victoria L. Seewaldt, MD
Molecular Medicine/Oncological Sciences Study Program, David Hsu, MD, PhD, Director;
Cory Adamson, MD, PhD, Co-Director

8:50 - Jesse Fitzpatrick
Inhibitors of Quinone Oxidoreductase 2 Improve Learning and Decrease Inflammation in a
Murine Model of Vascular Dementia
Mentor: Christopher Lascola, MD, PhD
Neuroscience Study Program, Christopher Lascola, MD, PhD, Director

9:00 - Whitney Lane
Improved endothelial integrity and functionality of rat vessel grafts with enhanced physiologic
storage solution
Mentor: Hardean Achneck, MD
Anesthesiology, Surgery and Environmental Physiology Study Program, Richard Moon, MD,
Director

9:10 - Pierre Elias
Development of an Electronic Health Record Data-Mining Algorithm to Predict In-Hospital
Venous Thromboembolism
Mentor: Bob Wachter, MD; University of California, San Francisco
Clinical Research Study Program, Vivian Chu, MD, Director

9:20 - Allison Ta
Fully Quantitative Pixel-wise Analysis of Cardiovascular MRI Perfusion Improves Diagnostic
Accuracy by Discriminating Dark Rim Artifact from True Perfusion Defects
Mentor: Andrew Arai, MD; NIH: National Heart, Lung and Blood Institute, Washington, DC
Clinical Research Study Program, Vivian Chu, MD, Director

9:30 - Nina Anne Fainberg
Behavioral and neural phenotypes in a new mouse model containing a knock-in Atp1a3
mutation
Mentor: Mohamad A. Mikati, MD
Neuroscience Study Program, Christopher Lascola, MD, PhD, Director

9:40 - Yiannis Koullias
Evaluating Cancer Metastasis Using Engineered Metastatic Platforms
Mentor: Rhoda M. Alani, MD; Boston University School of Medicine
Biomedical Engineering Study Program, Bruce Klitzman, PhD, Director
9:50 - Laura Platt
The Role of Gender in Violence Experienced by People with Developmental Disabilities
Mentor: Christina Nicolaidis, MD, MPH; Oregon Health & Science University
Primary Care Leadership Program, Anh Tran, PhD, MPH, Director

10:00 - Matt Susko
Enhancing pancreatic cancer responsiveness to chemotherapy agents through inhibition of the
pentose phosphate pathway
Mentor: Sally Kornbluth, PhD
Molecular Medicine/Oncological Sciences, David Hsu, MD, PhD, Director; Cory Adamson,
MD, PhD, Co-Director

10:10 - Ethan B. Ludmir
Proteomic Analysis of TrkB-Mediated Synaptic Changes following Status Epilepticus
Mentor: James O. McNamara, MD
Neuroscience Study Program, Christopher Lascola, MD, PhD, Director