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Affinity Capillary Electrophoresis in Pharmaceutics and Biopharmaceutics PDF

381 Pages·2003·3.102 MB·English
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About Affinity Capillary Electrophoresis in Pharmaceutics and Biopharmaceutics

This reference presents the most recent breakthroughs and techniques in affinity capillary electrophoresis (ACE) to measure and determine the physicochemical and thermodynamic parameters of drug compounds. The authors offer strategies to explore and characterize interactions between drugs, drug vehicles, and biological membranes to facilitate developments in controlled drug delivery and targeting. The book contains current applications and procedures to identify binding constants between drugs, biological structures, proteins, nucleic acids, and plasmids, increase drug bioavailability, enhance the permeability, solubility, strength, and function of drug formulations, examine protein-protein exchanges and reactions, and calculate pKa values.

Detailed Information

Author:Reinhard Neubert (Editor), Hans-Hermann Ruttinger (Editor)
Publication Year:2003
ISBN:9780824747367
Pages:381
Language:English
File Size:3.102
Format:PDF
Price:FREE
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