Advances in Biomaterials for Biomedical Applications

553 Pages·2017·12.005 MB·English

by  Anuj Tripathi, Jose Savio Melo (eds.)

Advanced Structured Materials
Anuj Tripathi
Jose Savio Melo Editors
Advances in
Biomaterials
for Biomedical
Applications
Advanced Structured Materials
Volume 66
Series editors
Andreas Öchsner, Southport Queensland, Australia
Lucas F.M. da Silva, Porto, Portugal
Holm Altenbach, Magdeburg, Germany
More information about this series at http://www.springer.com/series/8611
Anuj Tripathi Jose Savio Melo
(cid:129)
Editors
Advances in Biomaterials
for Biomedical Applications
123
Editors
AnujTripathi Jose SavioMelo
Nuclear Agriculture andBiotechnology Nuclear Agriculture andBiotechnology
Division Division
Bhabha Atomic Research Centre Bhabha Atomic Research Centre
Mumbai,Maharashtra Mumbai,Maharashtra
India India
ISSN 1869-8433 ISSN 1869-8441 (electronic)
AdvancedStructured Materials
ISBN978-981-10-3327-8 ISBN978-981-10-3328-5 (eBook)
DOI 10.1007/978-981-10-3328-5
LibraryofCongressControlNumber:2016960027
©SpringerNatureSingaporePteLtd.2017
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Preface
Ameteoric scientificand technological revolutionin biomedicineisunderwayand
is ruling by advanced biomaterials. A number offactors involved in biomaterials’
advancement complement each other. Science of materials, synthesis procedures,
andanalyticalcontrivancearesomeofthemajorfactorsthathavetransformedover
a period of time, thus popularizing the biomaterials for their advanced biomedical
applications.Muchofrevolutioninbiomaterialsisfundamentalinnature;however,
advancesareoftenbasedonthenewandextendedunderstandingofbasicprinciples
of biomaterials along with its applications.
Biomaterials are a class of materials that are intended for applications in the
biomedicalfieldwithoutbeingbiologicallyvulnerable.Amongmany,metallicand
polymeric biomaterials have most widely been studied due to several advantages.
The growing number of publications and technology patents in this field has
encouraged us to provide a comprehensive outcome with future scope. We have
selectively chosen topics based on the latest and demanding areas of research in
biomedicine. Each chapter of this book has discussed distinct biomaterial types.
Manychaptersbeginwiththebasicsfollowedbyadvancementandthenapplication
of biomaterial. Overall, this book elaborates on the preparation process and mod-
ificationofpolymers,blends,composites,nanoclusters,andnanohybrids,including
advanced approaches such as bioprinting and plasma processing. These biomate-
rials have further been discussed in terms of their application as a carrier for drug
and gene delivery, imaging and sensing, and also as an adjuvant, which are espe-
cially elaboratedinthe fieldofcartilage regenerationtherapy,cancer management,
and for the induction and treatment of autoimmunity, respectively. The use of
polymeric scaffolds for engineering tumor microenvironment and decellularized
extracellular matrix as the scaffolds for various tissue recreations has also indi-
viduallybeendiscussedinseparatechapters.Thevariousnanohybridsystemssuch
as gold nanoclusters, graphene nanoclusters, and magnetic nanoparticles and var-
ious nanoantimicrobial biomaterials have also been elaborated as advanced thera-
nostics and developing antimicrobial biomaterials, respectively.
Arduous task of compiling recent ‘Advances in Biomaterials for Biomedical
Applications’andsuccinctpretensionabouttheirfuturerequiresgreaterleisureand
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vi Preface
extensive reading. In this book, we have sought to bring together the expertise of
scientists involved in the materials chemistry and theranostics, with the aim of
providing overview on contemporary preparation and diversified applications of
biomaterials. This book is appropriate to advanced graduate, introductory-level
researchers,andalsointerdisciplinaryandmultidisciplinaryscientists.Itshouldalso
serve as a source book for statuary authorities and legislators charged with ethical
monitoring and approving clinical applications.
Weonceagainthankalltheauthorsforthequalityoftheircontributionsthathas
enabled us to make possible this book beyond our own limited experience.
Mumbai, India Anuj Tripathi
Jose Savio Melo
Contents
Polymers, Blends and Nanocomposites for Implants,
Scaffolds and Controlled Drug Release Applications ... .... ..... .... 1
Kumar Abhinav Dubey, Chandrashekhar V. Chaudhari,
Yatendra Kumar Bhardwaj and Lalit Varshney
Polyelectrolyte Complexes (PECs) for Biomedical Applications.... .... 45
Manisha Buriuli and Devendra Verma
Plasma Surface Modification of Biomaterials
for Biomedical Applications.. ..... .... .... .... .... .... ..... .... 95
Ajinkya M. Trimukhe, Krishnasamy N. Pandiyaraj, Anuj Tripathi,
Jose Savio Melo and Rajendra R. Deshmukh
Biomaterials for Induction and Treatment of Autoimmunity ..... .... 167
Akhilesh Kumar Shakya and Kutty Selva Nandakumar
Decellularized Tissue Engineering.. .... .... .... .... .... ..... .... 185
Nana Shirakigawa and Hiroyuki Ijima
Current Progress in Bioprinting ... .... .... .... .... .... ..... .... 227
Xiao-Fei Zhang, Ying Huang, Guifang Gao and Xiaofeng Cui
Controlled Gene Delivery Systems for Articular Cartilage Repair . .... 261
Magali Cucchiarini and Ana Rey-Rico
Biomaterials Based Strategies for Engineering Tumor
Microenvironment.. .... .... ..... .... .... .... .... .... ..... .... 301
Neha Arya and Aurelien Forget
Magnetic Nanoparticles: Functionalization and Manufacturing
of Pluripotent Stem Cells .... ..... .... .... .... .... .... ..... .... 363
Masanobu Horie, Anuj Tripathi, Akira Ito, Yoshinori Kawabe
and Masamichi Kamihira
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Fluorescent Gold Nanoclusters as a Powerful Tool for Sensing
Applications in Cancer Management.... .... .... .... .... ..... .... 385
ShijiR,ManuM.Joseph,UnnikrishnanBS,PreethiGUandSreelekhaTT
Graphene Metal Nanoclusters in Cutting-Edge Theranostics
Nanomedicine Applications .. ..... .... .... .... .... .... ..... .... 429
Kasturi Muthoosamy, RenuGeetha Bai and Sivakumar Manickam
Development of Nano-Antimicrobial Biomaterials
for Biomedical Applications.. ..... .... .... .... .... .... ..... .... 479
Shekhar Agnihotri and Navneet Kaur Dhiman
Editors and Contributors
About the Editors
Dr. Anuj Tripathi is a scientist at the Bhabha Atomic Research Centre, Mumbai,
India.HeisalsoanadjunctfacultyattheHomiBhabhaNationalInstitute,Mumbai,
India.HeisarecipientoftheK.S.KrishnanresearchfellowshipfromtheBoardof
ResearchinNuclearSciences,India.HehasbeenavisitingresearcheratNewcastle
University,UK;KyushuUniversity,Japan;andProtistaInternationalABandLund
University, Sweden. He has received several research fellowships from the
Government of India funding organizations such as DBT, CSIR, DST, and HLL.
He has several international research publications, book chapters, conference arti-
cles,andpatentstohiscredit.Heisanactiveparticipantinmanyscientificdeedsin
India for the promotion of biotechnology and materials science. He is an editorial
board member of many journals and also a member of several international aca-
demic societies. He has received awards from various national and international
organizations such as the Asian Polymer Association, Association of Separation
Scientists and Technologists, and Indian Thermal Analysis Society. His major
research interests are in the area of novel nano- and biomaterials development for
tissue engineering, bioprocessing, and environmental biotechnology.
Dr. Jose Savio Melo is a senior scientist at the Bhabha Atomic Research Centre,
India, where he heads the Enzyme and Microbial Technology Section of the
Nuclear Agriculture and Biotechnology Division. His major research interest is in
the field of applied enzymology with a special focus on designing heterogeneous
biocatalysts for use in bioprocessing, biosensors, and bioremediation. He is also a
professor at the Homi Bhabha National Institute (HBNI), Mumbai. He has several
publications in international journals, books, and workshop proceedings to his
creditandisafellowofboththeMaharashtraAcademyofSciencesandtheSociety
for Applied Biotechnology.
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