Advanced Materials for Biomedical Applications

293 Pages·2022·24.651 MB·English

by  Ashwani Kumar, Yatika Gori, Avinash Kumar, Chandan Swaroop Meena, Nitesh Dutt

Advanced Materials for
Biomedical Applications
This textbook discusses the synthesis, processing, design, simulation, and
characterization of biomaterials for biomedical applications. It synergizes
exploration related to various properties and functionalities in the bio-
medical feld through extensive theoretical and experimental modeling. It
further presents advanced integrated design and nonlinear simulation prob-
lems occurring in the biomedical engineering feld. It will serve as an ideal
reference text for senior undergraduate and graduate students, and aca-
demic researchers in felds including biomedical engineering, mechanical
engineering, materials science, ergonomics, and human factors.
This book
• Employs a problem-solution approach, where, in each chapter, a spe-
cifc biomedical engineering problem is raised and its numerical and
experimental solutions are presented.
• Covers recent developments in biomaterials such as OPMF/KGG bio-
composites, PEEK-based biomaterials, PF/KGG biocomposites, oil palm
mesocarp fber/KGG biocomposite, and polymeric resorbable materials
for orthopedic, dentistry, and shoulder arthroplasty applications.
• Discusses mechanical performance and corrosive analysis of biomate-
rials for biomedical applications in detail.
• Presents advanced integrated design and nonlinear simulation prob-
lems occurring in the biomedical engineering feld.
• Presents biodegradable polymers for various biomedical applications
over the last decade owing to their non-corrosion in the body, biocom-
patibility, and superior strength in growing state.
• Synergizes exploration related to various properties and functional-
ities in the biomedical feld through extensive theoretical and experi-
mental modeling.
Advances in Manufacturing, Design and
Computational Intelligence Techniques
Series Editor:
Ashwani Kumar
Advanced Materials for Biomedical Applications
Ashwani Kumar, Yatika Gori, Avinash Kumar,
Chandan Swaroop Meena, and Nitesh Dutt
For more information about this series, please visit: https://www.routledge.
com/Advances-In-Manufacturing-Design-andComputational-Intelligence-
Techniques/book-series/%20CRCAIMDCIT
Advanced Materials for
Biomedical Applications
Edited by
Ashwani Kumar, Yatika Gori, Avinash Kumar,
Chandan Swaroop Meena, and Nitesh Dutt
First edition published 2023
by CRC Press
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and by CRC Press
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CRC Press is an imprint of Taylor & Francis Group, LLC
© 2023 selection and editorial matter, Ashwani Kumar, Yatika Gori, Avinash Kumar, Chandan
Swaroop Meena and Nitesh Dutt; individual chapters, the contributors
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ISBN: 9781032356068 (hbk)
ISBN: 9781032356075 (pbk)
ISBN: 9781003344810 (ebk)
DOI: 10.1201/9781003344810
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Contents
Preface ix
Acknowledgments xiii
Editors xv
Contributors xix
1 Recent advancements and future trends in next-generation
materials for biomedical applications 1
AVINASH KUMAR, ANKA DATTA, ASHWANI KUMAR, AND ABHISHEK KUMAR
2 Advanced materials in biological implants and
surgical tools 21
ANKA DATTA, AVINASH KUMAR, ASHWANI KUMAR, ABHISHEK KUMAR,
AND VARUN PRATAP SINGH
3 Design and fabrication of augmented glenoid implants
in  total shoulder arthroplasty 45
CHAMAIPORN SUKJAMSRI AND VAMSI KRISHNA PASAM
4 Fabrication and cost optimization of 3D printed mandible
for applications in dentistry 67
ANIL KUMAR BIRRU, AMANDEEP KAUR, AND KHUNDRAKPAM NIMO SINGH
5 Synthesis, properties, and applications of PEEK-based
biomaterials 81
S. SATHISHKUMAR, P. JAWAHAR, AND PRASUN CHAKRABORTI
6 Morphology and Dielectric Characteristics of
OPMF/KGG biocomposites 109
V. SRIKANTH, K. RAJA NARENDER REDDY, AND R. SAI KUMAR
vii
viii Contents
7 Physical Properties of Surface Modification Impact on
Coir Fiber/KGG biocomposites 121
V. SRIKANTH, K. RAJA NARENDER REDDY, AND M. KEERTHIKA
8 Thermo-Mechanical and Morphological analysis of
PF/KGG bio-composites 133
V. SRIKANTH, K. RAJA NARENDER REDDY, P. ANIL KUMAR,
AND K. PUNNAM CHANDER
9 Posture analysis: current status and future trends 145
ARNAB SARMAH, SATOSHI ITO, AND SUBRAMANI KANAGARAJ
10 Turing test to validate perceptually reduced model
for needle insertion simulation 163
RAVALI GOURISHETTI AND M. MANIVANNAN
11 Microfluidics-based isolation of circulating tumor cells 185
ANJU R. BABU, ADHARSH RAJ M. K., AND BANSOD SNEHA BHARAT
12 Advanced abrasive-based nano-finishing process
parameter study for biomedical implants 201
CHINU KUMARI AND SANJAY KUMAR CHAK
13 Thermal and dynamic mechanical analysis of oil
palm mesocarp fiber/Kondagogu gum biocomposites 219
V. SRIKANTH AND K. RAJA NARENDER REDDY
14 Biomedical study of femur bone fracture and healing 235
ASHWANI KUMAR, ARUN KUMAR SINGH GANGWAR, AVINASH KUMAR,
CHANDAN SWAROOP MEENA, VARUN PRATAP SINGH, NITESH DUTT,
ARBIND PRASAD, AND YATIKA GORI
15 Bio-based environmentally benign polymeric resorbable
materials for orthopedic fixation applications 251
ARBIND PRASAD, GOURHARI CHAKRABORTY, AND ASHWANI KUMAR
Index 267
Preface
Advanced Materials for Biomedical Applications consists of the synthe-
sis, processing, design, simulation, and characterization of biomaterials
for biomedical applications. Advanced materials for biomedical appli-
cations are the central theme of the book. Biomaterials are used in bone
plates, joint replacement, bone cement, surgical sutures, clips and staples to
close wounds, pins and screws to stabilize fractures, surgical mesh, breast
implants, artifcial ligaments and tendons, dental implants for teeth stabi-
lization, blood vessel prostheses, heart valves, vascular grafts, stents, nerve
conduits, skin repair devices, intraocular lenses in eye surgery, contact
lenses, drug delivery systems, etc. There is a huge demand for biomedical
fxations devices and implants. The resorbable material plays a vital role
in developing and mimicking the bone. From the industry point of view,
many processing techniques are researched in the biomedical domain in a
very cost-effective way. Many conventional metals such as SS304, titanium
alloys, and magnesium alloys have many biomedical limitations. So, there
is a need of the hour to introduce new materials and their manufacturing
techniques to the medical world. This book content is helpful to practitio-
ners in felds of orthopedic, dental, and cardiology departments.
Chapters 1 and 2 provide details about the recent developments in bioma-
terials and their broad applications. Chapter 1 deals with future trends in
next-generation smart materials for biomedical applications. Smart materi-
als may now provide wonderful capabilities such as controlled treatments
by fne-tuning certain stimulus agents to improve therapeutic effciency.
Dual- or multistimuli-responsive smart materials, which may activate sev-
eral functionalities on a single smart nanomaterial, have lately received
increased attention in order to enhance illness diagnostics. In addition,
Chapter 2 deals with biological implants and surgical tool materials. A vast
range of medical, assistive, and surgical instruments have been developed
to improve human life. The aging population, accidents, and sports-related
injuries are driving the ever-increasing need for ortho-, dental, cardiologic,
ophthalmic, and IVD equipment, as well as enhanced diagnostic tests, in
the worldwide medical device market.
ix