A Clinical Guide to Gluten-Related Disorders

192 Pages·2014·4.873 MB·English

by  Fasano, Alessio

A Clinical Guide to
Gluten-Related Disorders
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A Clinical Guide to
Gluten-Related Disorders
Alessio Fasano, MD
Medical Director
Mucosal Immunology and Biology Research Center and Center for Celiac Research
Massachusetts General Hospital
Division of Pediatric Gastroenterology and Nutrition
Massachusetts General Hospital for Children
Boston, Massachusetts
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Senior Executive Editor: Rebecca S. Gaertner
Product Manager: Ashley Fischer
Production Product Manager: David Orzechowski
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© 2014 by LIPPINCOTT WILLIAMS & WILKINS, a WOLTERS KLUWER business
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All rights reserved. This book is protected by copyright. No part of this book may be reproduced in any form by
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Library of Congress Cataloging-in-Publication Data
A clinical guide to gluten-related disorders / [edited by] Alessio Fasano. — First edition.
p. ; cm.
Includes bibliographical references.
ISBN 978-1-4511-8263-7
I. Fasano, Alessio, editor of compilation.
[DNLM: 1. Celiac Disease—therapy. 2. Celiac Disease—diagnosis. 3. Celiac Disease—psychology.
4. Glutens—adverse effects. 5. Wheat Hypersensitivity—physiopathology. WD 175]
RC862.C44
616.3¿99—dc23
2013017488
Care has been taken to confirm the accuracy of the information presented and to describe generally accepted
practices. However, the authors, editors, and publisher are not responsible for errors or omissions or for any
consequences from application of the information in this book and make no warranty, expressed or implied,
with respect to the currency, completeness, or accuracy of the contents of the publication. Application of the
information in a particular situation remains the professional responsibility of the practitioner.
The authors, editors, and publisher have exerted every effort to ensure that drug selection and dosage set forth
in this text are in accordance with current recommendations and practice at the time of publication. However,
in view of ongoing research, changes in government regulations, and the constant flow of information relating
to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change
in indications and dosage and for added warnings and precautions. This is particularly important when the
recommended agent is a new or infrequently employed drug.
Some drugs and medical devices presented in the publication have Food and Drug Administration (FDA)
clearance for limited use in restricted research settings. It is the responsibility of the health care provider to
ascertain the FDA status of each drug or device planned for use in their clinical practice.
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Dedications
I like to dedicate this book to all those patients affected by gluten-related disorders
who look at us as the best hope to improve their quality of life. This book is also
dedicated to those who are not with us anymore but who have been and continue
to be a strong presence in my life.
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Contributors
Carlo Catassi, MD, MPH Thomas Flass, MD, MS
Professor Fortin Pediatric Specialty Clinic
Department of Pediatrics St. Vincent Physician Network
Università Politecnica delle Marche Billings, Montana
Ancona, Italy
Co-Director, Center for Celiac Research Joel Friedlander, DO, MA
Massachusetts General Hospital for Children Bioethics, Assistant Professor
Boston, Massachusetts Children’s Hospital Colorado Center for
Celiac Disease
Pam Cureton, RD, LDN Digestive Health Institute
Center for Celiac Research Children’s Hospital Colorado
Massachusetts General Hospital for Children University of Colorado School of Medicine
Boston, Massachusetts Aurora, Colorado
Valentina Discepolo, MD
Stefano Guandalini, MD
Pediatric Resident
Professor, Department of Pediatrics
Department of Pediatrics
Chief, Section of Pediatric Gastroenterology,
Section of Pediatric Gastroenterology,
Hepatology and Nutrition
Hepatology, and Nutrition
University of Chicago
University of Chicago
Chicago, Illinois
Chicago, Illinois
Department of Pediatrics
Ivor Hill, MB, ChB, MD
Università di Napoli “Federico II”
Professor of Clinical Pediatrics
Naples, Italy
The Ohio State University College of Medicine
Division of Gastroenterology
Alessio Fasano, MD
Nationwide Children’s Hospital
Medical Director
Columbus, Ohio
Mucosal Immunology and Biology Research
Center and Center for Celiac Research
Massachusetts General Hospital
Division of Pediatric Gastroenterology and
Nutrition
Massachusetts General Hospital for Children
Boston, Massachusetts
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viii Contributors
Edward J. Hoffenberg, MD Nomi Levy-Carrick, MD, MPhil
Professor Clinical Instructor
Children’s Hospital Colorado Center for Department of Psychiatry
Celiac Disease New York University School of Medicine
Digestive Health Institute Mental Health Director
Children’s Hospital Colorado WTC Environmental Health Center
University of Colorado School of Medicine Bellevue Hospital Center
Aurora, Colorado New York, New York
Karoly Horvath, MD, PhD
Edwin Liu, MD
Clinical Professor
Associate Professor
The Florida State University
Children’s Hospital Colorado Center for
Director, Celiac Center
Celiac Disease
Center for Digestive Health and Nutrition
Digestive Health Institute
Arnold Palmer Hospital for Children
Children’s Hospital Colorado
Orlando, Florida
University of Colorado School of Medicine
Aurora, Colorado
Robert Kramer, MD
Associate Professor
Devendra I. Mehta, MD
Children’s Hospital Colorado Center for
Clinical Associate Professor
Celiac Disease
The Florida State University
Digestive Health Institute
Center for Digestive Health and Nutrition
Children’s Hospital Colorado
Arnold Palmer Hospital for Children
University of Colorado School of Medicine
Orlando, Florida
Aurora, Colorado
Sonia Kupfer, MD Naina Mehta, MD
Assistant Professor Neurodevelopmental Pediatrician
Department of Medicine Children’s Medical Services
Division of Gastroenterology Florida Department of Health
University of Chicago Orlando, Florida
Chicago, Illinois
Catherine Newland, MD
Cynthia Kupper, RD Assistant Professor
Executive Director Section of Pediatric Gastroenterology
Gluten Intolerance Group Department of Pediatrics University
Auburn, Washington of Iowa
Iowa City, Iowa
Anne Lee, MSEd, RD, LD
Director of Nutritional Services
Tina Rakitt, MD
Dr. Schar USA, Inc.
Assistant Professor
Lyndhurst, New Jersey
Drexel University College of Medicine
Joseph Levy, MD The Children’s Hospital at Monmouth Medical
Professor Center
Department of Pediatrics Department of Pediatric Gastroenterology
Director Long Branch, New Jersey
Division of Pediatric Gastroenterology
New York University School of Medicine
New York, New York
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Co ntributo rs ix
Anna Sapone, MD, PhD Mary K. Sharrett, MS, RD, CNSC, LD
Department of Gastroenterology Nationwide Children’s Hospital
Experimental Medicine Department Columbus, Ohio
Magrassi-Lanzara Service
Second University of Naples Suzanne Simpson, RD
Naples, Italy Celiac Disease Center
Columbia University
Yamen Smadi, MD New York, New York
Gastroenterology Fellow
Center for Digestive Health Tricia Thompson, MS, RD
and Nutrition Founder
Arnold Palmer Hospital for Children Gluten Free Watchdog, LLC
Orlando, Florida Manchester, Massachusetts
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