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About 4) Conversion of An Active Compound To Another Equally Active Compound (No Change in Activity)
Drug metabolism involves converting substances like drugs and toxins to different chemical forms so they can be more easily eliminated from the body. Biotransformation specifically refers to these chemical transformations that occur in living systems. The goals of biotransformation are to inactivate compounds, activate prodrugs, or change a compound's pharmacological effects. It occurs in two phases: phase I involves reactions like oxidation and hydrolysis, while phase II involves conjugating compounds to make them more polar and excretable, through reactions like glucuronidation and sulfation. Many factors can influence an individual's drug metabolism, such as age, health conditions, genetics, and interactions with other drugs or diet.
Detailed Information
Author: | ['Surjeet Chauhan'] |
---|---|
Publication Year: | 2020 |
Pages: | 5 |
Language: | English |
Format: | |
Price: | FREE |
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