Table Of ContentIFMBE Proceedings Volume 16/1
Series Editors: R. Magjarevic and J. H. Nagel
The International Federation for Medical and Biological Engineering, IFMBE, is a federation of national and transnational organizations representing
internationally the interests of medical and biological engineering and sciences. The IFMBE is a non-profit organization fostering the creation, dis-
semination and application of medical and biological engineering knowledge and the management of technology for improved health and quality of
life. Its activities include participation in the formulation of public policy and the dissemination of information through publications and forums.
Within the field of medical, clinical, and biological engineering, IFMBE’s aims are to encourage research and the application of knowledge, and to
disseminate information and promote collaboration. The objectives of the IFMBE are scientific, technological, literary, and educational.
The IFMBE is a WHO accredited NGO covering the full range of biomedical and clinical engineering, healthcare, healthcare technology and man-
agement. It is representing through its 58 member societies some 120.000 professionals involved in the various issues of improved health and health
care delivery.
IFMBE Officers
President: Makoto Kikuchi, Vice-President: Herbert Voigt, Past-President: Joachim H. Nagel
Treasurer: Shankar M. Krishnan, Secretary-General: Ratko Magjarevic
http://www.ifmbe.org
Previous Editions:
IFMBE Proceedings MEDICON 2007 “11th Mediterranean Conference on Medical and Biological Engineering
and Computing 2007”, Vol. 16, 2007, Ljubljana, Slovenia, CD
IFMBE Proceedings BIOMED 2006 “Kuala Lumpur International Conference on Biomedical Engineering”,
Vol. 15, 2004, Kuala Lumpur, Malaysia, CD
IFMBE Proceedings WC 2006 “World Congress on Medical Physics and Biomedical Engineering”,
Vol. 14, 2006, Seoul, Korea, DVD
IFMBE Proceedings BSN 2007 “4th International Workshop on Wearable and Implantable Body Sensor Networks”,
Vol. 13, 2006, Aachen, Germany
IFMBE Proceedings ICBMEC 2005 “The 12th International Conference on Biomedical Engineering”,
Vol. 12, 2005, Singapore, CD
IFMBE Proceedings EMBEC’05 “3rd European Medical & Biological Engineering Conference, IFMBE European
Conference on Biomedical Engineering”, Vol. 11, 2005, Prague, Czech Republic, CD
IFMBE Proceedings ICCE 2005 “The 7th International Conference on Cellular Engineering”,
Vol. 10, 2005, Seoul, Korea, CD
IFMBE Proceedings NBC 2005 “13th Nordic Baltic Conference on Biomedical Engineering and Medical Physics”,
Vol. 9, 2005, Umeå, Sweden
IFMBE Proceedings APCMBE 2005 “6th Asian-Pacific Conference on Medical and Biological Engineering”,
Vol. 8, 2005, Tsukuba, Japan, CD
IFMBE Proceedings BIOMED 2004 “Kuala Lumpur International Conference on Biomedical Engineering”,
Vol. 7, 2004, Kuala Lumpur, Malaysia
IFMBE Proceedings MEDICON and HEALTH TELEMATICS 2004 “X Mediterranean Conference on Medical
and Biological Engineering”, Vol. 6, 2004, Ischia, Italy, CD
IFMBE Proceedings 3rd Latin – American Congress on Biomedical Engineering “III CLAEB 2004”,
Vol. 5, 2004, Joao Pessoa, Brazil, CD
IFMBE Proceedings WC2003 “World Congress on Medical Physics and Biomedical Engineering”,
Vol. 4, 2003, Sydney, Australia, CD
IFMBE Proceedings EMBEC'02 “2nd European Medical and Biological Engineering Conference”,
Vol. 3, Parts 1 & 2, 2002, H. Hutten and P. Kroesl (Eds.), Vienna, Austria
IFMBE Proceedings 12NBC “12th Nordic Baltic Conference on Biomedical Engineering and Medical Physics”,
Vol. 2, 2002, Stefan Sigurdsson (Ed.) Reykjavik, Iceland
IFMBE Proceedings MEDICON 2001 – “IX Mediterranean Conference on Medical Engineering and Computing”,
Vol. 1, Parts 1 & 2, 2001, R. Magjarevic, S. Tonkovic, V. Bilas, I. Lackovic (Eds.), Pula, Croatia
IFMBE Proceedings Vol. 16/1
T. Jarm, P. Kramar, A. Županič (Eds.)
11th Mediterranean Conference on Medical
and Biological Engineering and Computing
2007
MEDICON 2007, 26 – 30 June 2007
Ljubljana, Slovenia
123
Editors
Tomaž Jarm Anže Županič
University of Ljubljana University of Ljubljana
Faculty of Electrical Engineering Faculty of Electrical Engineering
Trzaska 25 Trzaska 25
1000 Ljubljana, Slovenia 1000 Ljubljana, Slovenia
E-Mail:
About IFMBE
The International Federation for Medical and Biological Engineering (IFMBE) was established in 1959 to provide medical
and biological engineering with a vehicle for international collaboration in research and practice of the profession. The Fed-
eration has a long history of encouraging and promoting international cooperation and collaboration in the use of science and
engineering for improving health and quality of life.
The IFMBE is an organization with membership of national and transnational societies and an International Academy. At
present there are 52 national members and 5 transnational members representing a total membership in excess of 120 000
worldwide. An observer category is provided to groups or organizations considering formal affiliation. Personal membership
is possible for individuals living in countries without a member society The International Academy includes individuals who
have been recognized by the IFMBE for their outstanding contributions to biomedical engineering.
Objectives
The objectives of the International Federation for Medical and Biological Engineering are scientific, technological, literary,
and educational. Within the field of medical, clinical and biological engineering it’s aims are to encourage research and the
application of knowledge, and to disseminate information and promote collaboration.
In pursuit of these aims the Federation engages in the following activities: sponsorship of national and international meet-
ings, publication of official journals, cooperation with other societies and organizations, appointment of commissions on
special problems, awarding of prizes and distinctions, establishment of professional standards and ethics within the field, as
well as other activities which in the opinion of the General Assembly or the Administrative Council would further the cause
of medical, clinical or biological engineering. It promotes the formation of regional, national, international or specialized
societies, groups or boards, the coordination of bibliographic or informational services and the improvement of standards in
terminology, equipment, methods and safety practices, and the delivery of health care.
The Federation works to promote improved communication and understanding in the world community of engineering,
medicine and biology.
Activities
Publications of IFMBE include: the journal Medical and Biological Engineering and Computing, the electronic magazine
IFMBE News, and the Book Series on Biomedical Engineering. In cooperation with its international and regional confer-
ences, IFMBE also publishes the IFMBE Proceedings Series. All publications of the IFMBE are published by Springer Ver-
lag. The Federation has two divisions: Clinical Engineering and Health Care Technology Assessment.
Every three years the IFMBE holds a World Congress on Medical Physics and Biomedical Engineering, organized in co-
operation with the IOMP and the IUPESM. In addition, annual, milestone and regional conferences are organized in different
regions of the world, such as Asia Pacific, Europe, the Nordic-Baltic and Mediterranean regions, Africa and Latin America.
The administrative council of the IFMBE meets once a year and is the steering body for the IFMBE: The council is sub-
ject to the rulings of the General Assembly, which meets every three years.
Information on the activities of the IFMBE can be found on the web site at: http://www.ifmbe.org.
Foreword
It is our great pleasure to welcome you at the11th Mediterranean Conference on Medical and Biological Engineering and
Computing – the MEDICON 2007. After 24 years MEDICON conference is coming back to Slovenia, this time into its capi-
tal – Ljubljana. The MEDICON conferences are international events of high scientific standards with long lasting tradition
held every third year in one of the Mediterranean countries under the auspices of the International Federation for Medical
and Biological Engineering.
Biomedical engineering today is a well-recognized area of research. It brings together bright minds from diverse disci-
plines ranging from engineering, physics, and computer sciences on one side to biology and medicine on the other side. With
valuable assistance of members of the International Advisory Committee and Scientific Program Committee, the co-
organizing institutions and societies, our sponsors, and distinguished invited lecturers we will ensure that the research and
development presented at MEDICON 2007 plenary meetings, scientific sessions, and workshops will truly be relevant and
up-to-date.
MEDICON 2007 is taking place at the premises of University of Ljubljana, Faculty of Electrical Engineering. The choice
was obvious: Ljubljana is accessible and vivid, and the academic environment is familiar to all of us. As Ljubljana is located
in the centre of the country it offers an excellent opportunity also to explore on your own the remarkable variety of Slove-
nia’s scenery and national heritage. The Mediterranean coast of Primorska, Alpine resorts of Gorenjska, lovely hills and
primeval forests of Dolenjska and the far-reaching plains of Prekmurje are just few examples of regional diversity you can
encounter here. All these and other regions of Slovenia are easily accessible from Ljubljana within two hours of driving. We
will visit some of our jewels together: Bled and Postojna.
We feel confident that you will enjoy MEDICON 2007 both scientifically and socially. We will make every effort to
make MEDICON 2007 a memorable event. This is also the place where you will meet your old friends and make new ones.
Together we will all face new challenges imposed to us by our society and new technologies. We look forward to meeting
you all in Ljubljana.
Professor Damijan Miklavcic Professor Tadej Bajd
Organizing Committee Slovenian Society of Medical and Biological Engineering,
The Chairman The President
Conference details
Name: University of Maribor, Faculty of Roberto Merletti (Italy)
11th Mediterranean Conference on Electrical Engineering and Computer Lluis M. Mir (France)
Medical and Biological Engineering Science Marko Munih (Slovenia)
and Computing http://www.feri.uni-mb.si/ Mustapha Nadi (France)
podrocje.aspx Joachim Nagel (Germany)
Short name: Eberhard Neumann (Germany)
MEDICON 2007 Franjo Pernus (Slovenia)
Local Organizing Committee
Dejan Popovic (Denmark)
Venue: Damijan Miklavcic (Chairman) Robert Riener (Switzerland)
Ljubljana, SLOVENIA Tadej Bajd Gregor Sersa (Slovenia)
June 26–30, 2007 Imre Cikajlo Franc Solina (Slovenia)
Peter Gajsek Vlado Stankovski (Slovenia)
Tomaz Jarm Martin Stefancic (Slovenia)
Proceedings editors
Tadej Kotnik Vojko Strojnik (Slovenia)
Tomaz Jarm Peter Kramar Johannes Struijk (Denmark)
Peter Kramar Zlatko Matjacic Pascal Verdonck (Belgium)
Anze Zupanic Matjaz Mihelj Max A. Viergever (Netherlands)
Anze Zupanic Veljko Vlaisavljevic (Slovenia)
Robert Cugelj Damjan Zazula (Slovenia)
Organized by
Jadran Lenarcic Ales Zemva (Slovenia)
Slovenian Society for Medical and Sasa Markovic Tatjana Zrimec (Australia)
Biological Engineering Zvonimir Rudolf Anton Zupan (Slovenia)
Tomaz Slivnik Blaz Zupan (Slovenia)
Igor Ticar
In cooperation with:
International Advisory
University of Ljubljana, Faculty of Scientific Programme Committee
Electrical Engineering
Committee
Marcello Bracale (Italy)
http://www.fe.uni-lj.si/
Institute for Rehabilitation of Republic Maria Teresa Arredondo (Spain) Ivan Bratko (Slovenia)
of Slovenia Janez Bester (Slovenia) Mario Cifrek (Croatia)
http://www.ir-rs.si/ Manfred Bijak (Austria) David Elad (Israel)
IFMBE - International Federation for Wolfgang Birkfellner (Austria) Attilio Evangelisti(Italy)
Medical and Biological Engineering Bozidar Casar (Slovenia) Frederique Frouin (France)
http://www.ifmbe.org Stelios Christofides (Greece) Enrique J Gomez (Spain)
Institute of Oncology, Ljubljana, Slo- Igor Emri (Slovenia) Akos Jobbagy(Hungary)
venia Carlo Frigo (Italy) Prodromos Kaplanis (Cyprus)
http://www.onko-i.si/ Borut Gersak (Slovenia) Nicolas Pallikarakis (Greece)
Jozef Stefan Institute, Ljubljana, Slo- Milan Gregoric (Slovenia) Costantinos S. Pattichis (Cyprus)
venia Francis X. Hart (USA) Laura M. Roa (Spain)
http://www.ijs.si/ijsw William Harwin (UK) Herve Saint-Jalmes (France)
Clinical Center Ljubljana, Slovenia Ales Iglic (Slovenia) Mario Forjaz Secca (Portugal)
http://www2.kclj.si/ Paolo Inchingolo (Italy) Thomas Sinkjaer (Denmark)
European Federation of Organisations Franc Jager (Slovenia) Vesna Spasic Jokic (Serbia)
for Medical Physics Joze Jelenc (Slovenia) Stanko Tonkovic (Croatia)
http://www.efomp.org/ Rihard Karba (Slovenia) Jos van der Sloten (Belgium)
University of Ljubljana, Faculty of Nada Lavrac (Slovenia) Peter Veltink (Netherlands)
Computer and Information Science Ratko Magjarevic (Croatia)
http://www.fri.uni-lj.si/ Crt Marincek (Slovenia)
IFMBE Mediterranean Conferences on Medical and Biological Engineering 1977–2007
MEDICON 1977 – I Mediterranean Conference on Medical and Biological Engineering, 12–17 September 1977, Sorrento,
Italy
MEDICON 1980 – II Mediterranean Conference on Medical and Biological Engineering, 15–19 September 1980,
Marseilles, France
MEDICON 1983 – III Mediterranean Conference on Medical and Biological Engineering, 5–9 September 1983, Portoroz,
Yugoslavia
MEDICON 1986 – IV Mediterranean Conference on Medical and Biological Engineering, 9–12 September 1986, Seville,
Spain
MEDICON 1989 – V Mediterranean Conference on Medical and Biological Engineering, 29 August–1 September 1989,
Patras, Greece
MEDICON 1992 – VI Mediterranean Conference on Medical and Biological Engineering, 5–10 July 1992, Capri, Italy
MEDICON 1995 – VII Mediterranean Conference on Medical & Biological Engineering, 17–21 September 1995,
Jerusalem, Israel
MEDICON 1998 – VII Mediterranean Conference on Medical & Biological Engineering, 14–17 June 1998, Limassol,
Cyprus
MEDICON 2001 – IX Mediterranean Conference on Medical Engineering and Computing, 12–15 June 2001, Pula, Croatia
MEDICON and HEALTH TELEMATICS 2004, X Mediterranean Conference on Medical and Biological Engineering,
31 July–5 August 2004, Ischia, Italy
MEDICON 2007 – XI Mediterranean Conference on Medical Engineering and Computing June 26–30 2007, Ljubljana,
Slovenia
Content
Invited Lectures
EMITEL – an e-Encyclopedia for Medical Imaging Technology......................................................................................... 1
S. Tabakov, C. A. Lewis, A. Cvetkov, M. Stoeva, EMITEL Consortium
Control for Therapeutic Functional Electrical Stimulation.................................................................................................. 3
Dejan B. Popovic, Mirjana B. Popovic
Patient-Cooperative Rehabilitation Robotics in Zurich ........................................................................................................ 7
Robert Riener
From Academy to Industry: Translational Research in Biophysics .................................................................................. 10
R. Cadossi, M.D
Information Technology Solutions for Diabetes management and prevention Current Challenges
and Future Research directions............................................................................................................................................. 14
R. Bellazzi
Systemic Electroporation – Combining Electric Pulses with Bioactive Agents................................................................. 18
Eberhard Neumann,
Normal Sessions
Analysis of ECG
Intelligent Internet Based, High Quality ECG Analysis for Clinical Trials ...................................................................... 22
T.K. Zywietz, R. Fischer
Effects of vagal blockade on the complexity of heart rate variability in rats .................................................................... 26
M. Baumert, E. Nalivaiko and D. Abbott
Assessment of the Heart Rate Variability during Arousal from Sleep
by Cohen’s Class Time-Frequency Distributions................................................................................................................. 30
M.O. Mendez , A.M. Bianchi , O.P. Villantieri and S. Cerutti
An algorithm for classification of ambulatory ECG leads according to type of transient ischemic episodes................. 34
A. Smrdel and F. Jager
Phase-Rectified Signal Averaging for the Detection of Quasi-Periodicities in Electrocardiogram ................................. 38
R. Schneider, A. Bauer, J.W. Kantelhardt, P. Barthel and G. Schmidt
Relative contribution of heart regions to the precordial ECG-an inverse computational approach .............................. 42
A.C. Linnenbank, A. van Oosterom, T.F. Oostendorp, P.F.H.M. van Dessel, A.C. van Rossum, R. Coronel, H.L. Tan,
J.M.T. de Bakker
Classification Methods for Atrial Fibrillation Prediction after CABG.............................................................................. 46
S. Sovilj, R. Magjarević and G. Rajsman
Modelling effects of Sotalol on Action Potential morphology using a novel Markov model
of the HERG channel.............................................................................................................................................................. 50
T.P. Brennan, M. Fink, B. Rodriguez, L.T. Tarassenko
Sample Entropy Analysis of Electrocardiograms to Characterize Recurrent Atrial Fibrillation................................... 54
R. Cervigon, C. Sanchez, J.M. Blas, R. Alcaraz, J. Mateo and J. Millet
USB Based ECG Acquisition System .................................................................................................................................... 58
J. Mihel, R. Magjarevic
XII Content
QT Intervals Are Prolonging Simultaneously with Increasing Heart Rate
during Dynamical Experiment in Healthy Horses............................................................................................................... 62
P. Kozelek, J. Holcik
FPGA-based System for ECG Beat Detection and Classification ...................................................................................... 66
M. Cvikl and A. Zemva
Feature extraction and selection algorithms in biomedical data classifiers based on time-frequency
and principle component analysis. ........................................................................................................................................ 70
P. S. Kostka, E. J. Tkacz
Dynamic Repolarization Assessment and Arrhythmic Risk Stratification........................................................................ 74
E. Pueyo, M. Malik and P. Laguna
Fractal analysis of heart rate variability in COPD patients................................................................................................ 78
G. D’Addio, A. Accardo, G. Corbi, N. Ferrara, F. Rengo
Autonomic Modulation of Ventricular Response by Exercise and Antiarrhythmic Drugs
during Atrial Fibrillation ....................................................................................................................................................... 82
VDA Corino, LT Mainardi, D Husser, A Bollmann
Flexible Multichannel System for Bioelectrical Fields Analysis ......................................................................................... 86
P. Kneppo, M. Tysler, K. Hana, P. Smrcka, V. Rosik, S. Karas, E. Heblakova
Neural Networks Based Approach to remove Baseline drift in Biomedical Signals ......................................................... 90
J. Mateo, C. Sanchez, R. Alcaraz, C. Vaya and J. J. Rieta
Non-Linear Organization Analysis of the Dominant Atrial Frequency to Predict Spontaneous Termination
of Atrial Fibrillation ............................................................................................................................................................... 94
R. Alcaraz and J. J. Rieta
Using Supervised Fuzzy Clustering and CWT for Ventricular Late Potentials (VLP) Detection
in High-Resolution ECG Signal............................................................................................................................................. 99
Ayyoub Jafari, M.H. Morradi
Analysis of Surface EMG
An Approach to the Real-Time Surface Electromyogram Decomposition...................................................................... 105
V. Glaser, A. Holobar and D. Zazula
Non-invasive estimation of the degree of motor unit synchronization in the biceps brachii muscle ............................ 109
A. Holobar, M. Gazzoni, D. Farina, D. Zazula, and R. Merletti
EMG Based Muscle Force Estimation using Motor Unit Twitch Model and Convolution Kernel Compensation...... 114
R. Istenic, A. Holobar , R. Merletti and D. Zazula
Model Based Decomposition of Muaps Into Their Constituent Sfeaps............................................................................ 118
M.G. Xyda, C.S. Pattichis, P. Kaplanis, C. Christodoulou and D. Zazula
Fast-Slow phase separation of Near InfraRed Spectroscopy to study Oxigenation v/s sEMG Changes....................... 124
Gian Carlo Filligoi
Analysis of Uterine EMG/EHG
Uterine Electromyography in Humans – Contractions, Labor, and Delivery................................................................. 128
R. E. Garfield and W. L. Maner
Predictive value of EMG basal activity in the cervix at initiation of delivery in humans .............................................. 131
D. Rudel, G. Vidmar, B. Leskosek and I. Verdenik
